ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Haoyue Qin,Yuanqiang Sun,Xin Geng,Keran Zhao,Hongmin Meng,Ran Yang,Lingbo Qu,Zhaohui Li
In this work, a novel bright yellow fluorescent carbon dots (CDs) was synthesized from N-methyl-1,2-phenylenediamine hydrochloride in ethanol solvent through the solvothermal method . The obtained carbon dots had no fluorescence in water, but could specifically light up in the cell which makes the staining process without washing. Interestingly, the imaging process can be performed by simply shaking the culture with the cells for only 1 min, indicating ultrafast and easy to operate fluorescence imaging. Moreover, the carbon dots with abundant amino functional groups had good lysosome targeting properties (the Pearson’s correlation coefficient is 0.92) and could achieve the ultrafast lysosome imaging in cell and zebrafish and monitoring cell apoptosis status. This is the first lysosome targeting carbon dots that allows the combination of a short incubation at the second-level with wash-free process providing great potential for continuous observation lysosome in vivo.
研究领域:
生物医学工程
·
细胞生物学
·
荧光成像
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DOI
PubMed
高影响因子
ENERGY & FUELS
·
2024
·
IF 5.2
Yan Li,Zhenyuan Yin,Yizhi Rao,Hongfeng Lu,Chenlu Xu,Xuejian Liu,Yang Li,Jianzhong Zhao,Praveen Linga
Hydrate-based CO2 sequestration (HBCS) technology is one promising method for reducing the CO2 level in the atmosphere for climate mitigation. However, the sluggish kinetics and low conversion rate of the CO2 hydrate hindered its practical applications. This study presents an innovative approach by coupling magnesium (Mg) with an amino acid l-leucine (l-Leu) to speed up the CO2 hydrate nucleation and realize the ultrarapid CO2 growth in the static system. The addition of a Mg sheet speeds up CO2 hydrate nucleation, resulting in an induction time less than 10 s compared with traditional ∼10 h in a static system. The coupling Mg sheet with l-Leu (1.0 wt %) shows optimal synergistic promotion effects on both CO2 hydrate nucleation and growth. The resulting final CO2 gas uptake is 78.9 Vg/Vw compared with 67.8 Vg/Vw without Mg. However, the t90 used is significantly shortened to 1.4 h compared with a t90 of 13.0 h without Mg. We further analyzed the possible promotion mechanism of Mg using a series of analytical methods, including Mg sheet surface morphology observation with element composition analysis, gas phase compositions analysis by GC and Mg2+ concentration in aqueous phase by ICP-MS. Corrosion of the Mg sheet surface is observed based on SEM images. A significant reduction of Mg is identified in the element composition analysis with additional C and N after corrosion. A small trace of hydrogen (∼1%) is identified in the gas phase with the Mg2+ in solution reaching 68 mg/L. Based on the experimental evidence, we propose that the abundant H2 bubbles released from the surface of the Mg sheet due to corrosion in the acidic environment of CO2 solution are one critical factor explaining the ultrarapid nucleation observed. Our study demonstrated that employing Mg corrosion to assist the nucleation of CO2 hydrate is effective in the static system and the coupling of amino acid can further enhance CO2 hydrate kinetics. The developed method can also be utilized for other hydrate-based technologies, such as flue gas separation and hydrogen storage, by coupling Mg with suitable promoters.
研究领域:
环境科学
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化学工程
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 77
·72985-72998
·
IF 3.289
Atian Xie,Jiangdong Dai,Xiang Chen,Jinsong He,Zhongshuai Chang,Yongsheng Yan,Chunxiang Li
Herein, waste paper towels, a mass garbage product from daily life, were used as precursors for the production of hierarchical porous carbon (PTHPC) via KOH activation to be used for the removal of tetracycline. In this study, the influence of KOH content on porosity and adsorption capacity was investigated, and the optimal property of hierarchical porous carbon was obtained at weight ratios of carbonization: KOH = 1 : 4 (PTHPC-4). The physico-chemical properties of PTHPC-4 were characterized by different technology. Notably, PTHPC-4 possesses an ultrahigh specific surface area of 3524 m2 g−1 and a large pore volume of 1.839 cm3 g−1. Additionally, the isothermal adsorption results showed that PTHPC-4 displayed an ultrahigh adsorption capacity of 1661.13 mg g−1 for tetracycline, which is superior to other previously reported adsorbents. Moreover, PTHPC-4 also has excellent kinetics performance: when C0 = 100 mg L−1, the pseudo-second-order kinetics constant k2 values at 298, 308 and 318 K are 1.055 × 10−2, 5.731 × 10−2 and 8.916 × 10−2 g mg−1 min−1, respectively, which were 1–3 magnitude higher than previously reported adsorbents. In addition, the investigation of the effect temperature, pH and ionic strength on the adsorption property for tetracycline are included in this study.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Lei Xing,Jieru Bao,Shiyu Zhou,Yulong Qiu,Hongji Sun,Shuai Gu,Jianguo Yu
Poor economics is the principal factor that hinders the commercialization of hydrometallurgy processing of spent lithium-ion batteries cathode materials. Here, ultra-fast leaching of spent cathode materials (97.72% Li and 97.25% Co leached under S/L ratio: 10 g/L, temperature: 363 K within 10 min) was achieved in 0.5 M hydrochloric acid and 0.5 M L -ascorbic acid system as part of reducing the costs of hydrometallurgy process. The correlations of both acids with the leaching ratios were studied for the first time with the Pearson correlation coefficient. The mixture of 0.5 M hydrochloric acid and 0.5 M L -ascorbic acid demonstrated both faster kinetics and higher leaching volume than those of aqua regia. Adopting quantum chemistry and thermodynamic calculations, four hypothetical mechanisms were proposed to interpret the reaction mechanisms. Synergy-coordination, with the lowest energy, was considered to be the most reasonable mechanism for the leaching of cathode materials. Three scenarios with different leaching systems and conditions were compared to identify the key parameters determining the economics of the leaching process.
研究领域:
环境科学
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化学工程
·
材料科学
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DOI
高影响因子
TALANTA
·
2015
·
IF 3.545
Xinpei Li,Yuanpeng Wang,Qun Sun,Bo Xu,Yong Yu,Xinghua Wang
A novel, cost-effective and simple solid phase extraction (SPE) method, by using a syringe connected with a nylon membrane filter as the adsorbent container, was developed for the extraction of triazine herbicides from Radix Paeoniae Alba (RPA) samples. The selective molecularly imprinted polymers (MIPs) synthesized with the template of atrazine were employed as the adsorbents for the enrichment and purification of analytes. The extraction parameters, including the volume and type of loading solvent, the type of washing solvent and eluting solvent, were investigated. Under the optimized conditions, the final extracts were analyzed by ultra-fast liquid chromatography (UFLC). Recoveries of the developed method range from 92.4% to 107.3% with intra- and inter-day relative standard deviations (RSDs) lower than 8.2%. The calibration curve is linear in the concentration range of 0.005–2.4 µg g −1 for desmetryn , atrazine and terbumeton , and 0.005–1.5 µg g −1 for dimethametryn and dipropetryn, with the correlation coefficient ( R 2 ) higher than 0.9995. The limits of detection (LODs) of five triazine herbicides are in the range of 0.09–0.39 ng g −1 , which are lower than the maximum residue levels (MRLs) established by various official organizations. Analytical results of three real Radix Paeoniae Alba samples indicate that the proposed method is cost-effective and easy-to-use than other routine pretreatment methods.
研究领域:
分析化学
·
中药学
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Jiawen Han,Xujuan Lv,Yuwei Zhang,Juan Wang,Daoqing Fan,Shaojun Dong
DNA logic nanodevices are powerful tools for both molecular computing tasks and smart bioanalytical applications. Nevertheless, the hour-level operation time and high cost caused by the frequent redesign/reconstruction of gates, tedious strand-displacement reaction, and expensive labeled probes (or tool enzymes) in previous works are ineluctable drawbacks. Herein, we report an ultrafast and cost-effective system for engineering concurrent DNA logic nanodevices (CDLNs) by combining polythymine CuNCs with SYBR Green I (SG I) as universal dual-output producers. Particularly, benefiting from the concomitant minute-level quick response of both unlabeled illuminators and the exquisite strand-displacement-free design, all CDLNs including contrary logic pairs (YES∧NOT, OR∧NOR, and Even∧Odd number classifier), noncontrary ones (IDE∧IMP, OR∧NAND), and concatenated circuits are implemented in just 10 min via a “one-stone-two-birds” method, resulting in only 1/12 the operation time and 1/4 the cost needed in previous works, respectively. Moreover, all of them share the same threshold value, and the dual output can be easily visualized by the naked eye under a portable UV lamp, indicating the universality and practicality of this system. Furthermore, by exploiting the “positive/negative cross-verification” advantages of concurrent contrary logic, the smart in vitro analysis of the polyadenine strand and its polymerase is realized, providing novel molecular tools for the early diagnosis of cancer-related diseases.
研究领域:
生物化学
·
分子生物学
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 189
·期 1
·1-13
·
IF 5.833
Xu Yeqing,Huang Ting,Meng Minjia,Yan Yongsheng
A highly effective fluorescent molecularly imprinted sensor (F-PDA-MIS) based on fluorescent polydopamine (F-PDA) was successfully synthesized for selective and ultrafast detection of p-nitrophenol (P-NP) in drinking water. F-PDA with abundant surface functional groups has been artfully modified to firstly serve as both fluorescent monomer and functional monomer in the synthesis of a uniform luminous F-PDA-MIS, which can greatly improve the detection efficiency. As expected, F-PDA-MIS had an obvious emission wavelength of 535 nm with the optimal excitation wavelength at 400 nm. Specially, F-PDA-MIS could detect P-NP in the range 100 to 1100 nM with much lower detection limit of 24.2 nM within 120 s compared with other conventional imprinted fluorescent sensors based on pure quantum dots (QDs) or dyes. This excellent test phenomenon is mainly ascribed to the rapid electron transfer between F-PDA and P-NP. Satisfactory recovery of 98.0–104% for mineral water and 98.6–106% for boiling water were obtained with relative standard deviations (RSDs) of 2.7–3.4% and 2.6–3.5% respectively. The detection reliability of F-PDA-MIS was verified by the comparison with high-performance liquid chromatography (HPLC–UV). Consequently, F-PDA as a fluorescence functional monomer has been shown to be a possible strategy to effectively improve the detection limit and shorten response time of the target determination in water.. Graphical abstract
研究领域:
环境科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·11573
·
IF 15.7
Wang Hongxing,Xu Yiheng,Li Panpan,Liu Qingjun,Cheng Longdi,Yu Jianyong,Si Yang
The Leidenfrost effect—where liquid droplets levitate on superheated surfaces—hinders efficient heat transfer. Conventional mitigation strategies typically rely on rigid materials with complex surface engineering, but their applicability is limited by stringent weight requirements, especially in aerospace systems where every gram counts. Here, through controlled tuning of the drying stress field and targeted welding of hollow nanofibers, we construct an aerogel-based Leidenfrost vapor percolator featuring directed nano/micro tunnels for efficient vapor evacuation and flow-topology reconstruction. This ultralight (7 mg cm −3 ) permeator robustly suppresses the Leidenfrost effect up to 1000 °C and achieves a high heat flux of 110.43 W cm −2 . Moreover, the permeator delivers a temperature drop of 760 °C under multi-flow injection, corresponding to a density-normalized Leidenfrost temperature reaching 142.9 °C cm 3 mg −1 . This two-order-of-magnitude enhancement over conventional materials highlights the pivotal roles of hierarchical structuring and vapor-channel regulation in overcoming the Leidenfrost barrier.
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-11
·
IF 14.7
Li Juanhua,Liu Yiren,Wu Tianyu,Xiao Zihan,Du Jianhang,Liang Hongrui,Zhou Cuiping,Zhou Jianhua
Acute myocardial infarction (AMI) has become a public health disease threatening public life safety due to its high mortality. The lateral-flow assay (LFA) of a typical cardiac biomarker, troponin I (cTnI), is essential for the timely warnings of AMI. However, it is a challenge to achieve an ultra-fast and highly-sensitive assay for cTnI (hs-cTnI) using current LFA, due to the limited performance of chromatographic membranes. Here, we propose a barbed arrow-like structure membrane (BAS Mem), which enables the unidirectional, fast flow and low-residual of liquid. The liquid is rectified through the forces generated by the sidewalls of the barbed arrow-like grooves. The rectification coefficient of liquid flow on BAS Mem is 14.5 (highest to date). Using BAS Mem to replace the conventional chromatographic membrane, we prepare batches of lateral-flow strips and achieve LFA of cTnI within 240 s, with a limit of detection of 1.97 ng mL −1 . The lateral-flow strips exhibit a specificity of 100%, a sensitivity of 93.3% in detecting 25 samples of suspected AMI patients. The lateral-flow strips show great performance in providing reliable results for clinical diagnosis, with the potential to provide early warnings for AMI.
研究领域:
生物医学工程
·
心脏病学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2020
·
IF 16.683
Kexin Li,Yun Zhong,Shenglian Luo,Wenying Deng
In this article, a series of powder and modular H 3 PW 12 O 40 /Ag 3 PO 4 composites were successfully fabricated for the first time by simple strategies. The as-prepared powder and modular H 3 PW 12 O 40 /Ag 3 PO 4 composites showed the unique photocatalytic characteristic of ultra-fast degradation of organic pollutants in water under visible-light. For the best powder H 3 PW 12 O 40 /Ag 3 PO 4 , 4-fluorophenol (4-FP) and methyl orange (MO) in water can be completely degraded and rhodamine B (RB) in water can be degraded to 78 % after 360 s of visible-light irradiation. For the best modular H 3 PW 12 O 40 /Ag 3 PO 4 , 4-FP, MO, and RB can be degraded to 84 %, 72 %, and 92 % after 30 min of visible-light irradiation. The reasons for this unique photocatalytic characteristic of as-prepared powder and modular H 3 PW 12 O 40 /Ag 3 PO 4 composites were systematically studied by various modern characterization strategies. The "four-step" strategy was proposed in order to realize the practical engineering application of as-prepared powder and modular H 3 PW 12 O 40 /Ag 3 PO 4 composites in photocatalytic organic wastewater treatment technology.
研究领域:
环境科学
·
材料科学
·
化学工程
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DOI
高影响因子
iScience
·
2023
·Vol. 26
·期 11
·108246-108246
·
IF 5.8
Peng Xie,Xiaoyue Yao,Zhenyu Chu,Yang Yang,Haifeng Li,Siyuan Tan,Haodong Tang,Jiahua Zhou,Wanqin Jin
The detection of circulating tumor cells (CTCs) in peripheral blood is a novel and accurate technique for the early diagnosis of cancers. However, this method is challenging because of the need for high collection efficiency due to the ultralow content and similar size of CTCs compared with other blood cells. To address the aforementioned issue, we proposed a homoporous polydimethylsiloxane (PDMS) membrane and its microfilter device to perform the ultrafast isolation and identification of CTCs directly from peripheral blood without any labeling treatment. The membrane pores can be homogenously controlled at a size of 6.3 μm through the cross-linking time of PDMS during a filtration-coating strategy. Within only 10 s, the designed device achieved a retention rate greater than 70% for pancreatic cancer cells, and it exhibited excellent cell compatibility to support cell proliferation. The isolated CTCs on this membrane can be easily observed and identified using a fluorescence microscope.
研究领域:
生物医学工程
·
癌症诊断
·
微流控技术
·
细胞分离
✓ 已验证
DOI
PubMed
高影响因子
Science Advances
·
2019
·Vol. 5
·期 4
·
IF 12.804
Wenxin Fan,Caiyun Shan,Hongyu Guo,Jianwei Sang,Rui Wang,Ranran Zheng,Kunyan Sui,Zhihong Nie
The design of materials that can mimic the complex yet fast actuation phenomena in nature is important but challenging. Herein, we present a new paradigm for designing responsive hydrogel sheets that can exhibit ultrafast inverse snapping deformation. Dual-gradient structures of hydrogel sheets enable the accumulation of elastic energy in hydrogels by converting prestored energy and rapid reverse snapping (<1 s) to release the energy. By controlling the magnitude and location of energy prestored within the hydrogels, the snapping of hydrogel sheets can be programmed to achieve different structures and actuation behaviors. We have developed theoretical model to elucidate the crucial role of dual gradients and predict the snapping motion of various hydrogel materials. This new design principle provides guidance for fabricating actuation materials with applications in tissue engineering, soft robotics, and active medical implants.
研究领域:
材料科学
·
仿生学
·
软体机器人
·
高分子科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）