CHEMISTRY OF MATERIALS
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2024
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IF 7.2
Xiaojiao Shi,Linli Xu,Qiuli Xu,Na Li,Xinyu Li,Yubin Zhang,Zhihui Qin,Tifeng Jiao
Conducting polymer hydrogels have been considered as promising materials for flexible sensors. The integrated performances of ultrasoftness, high deformation, mechanical robustness, conformal adhesion, and high sensitivity are of great importance for their applications in wearable sensors but still remains challenging. Herein, a highly deformable conducting polymer hydrogel with ultrasoftness, tear resistance, and self-adhesiveness is fabricated by incorporating poly(3, 4-ethylenedioxythiophene):poly(styrene sulfonic acid) (PEDOT:PSS) and silk sericin (SS) into a covalently cross-linked polyacrylamide (PAM) network. Owing to abundant noncovalent interactions among the folded SS chains, PAM chains, and PEDOT:PSS, the obtained hydrogel shows a low modulus (10.3 kPa), ultrastretchability (>2000%), particularly large biaxial strain (an areal strain of 1700%), high toughness (tearing energy of 2.5 kJ/m2), and good conformal adhesion. As a result, this hydrogel demonstrates superior strain-sensitivity (gauge factor = 13.8) in a broad strain range (2000%) and excellent sensing reproducibility. The hydrogel-based wearable sensor can be used for accurately monitoring large and tiny human movements in real time and serves as bioelectrodes for precise gathering of electrocardiography and electromyography signals, showing great potential for applications in flexible sensing devices.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
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2025
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IF 16
Bingsen Wang,Fagui Dong,Xisheng Sun,Yanan Bu,Haonan Wang,Dawei Tang,Lin Li
Achieving stable bioelectronic interfaces is hindered by inherent mechanical–electrochemical mismatches, limiting long-term device functionality in dynamic tissues. Current hydrogel-based bio-ionotronic devices face a fundamental trade-off: soft hydrogels lack sufficient ionic carriers, while ionic hydrogels compromise softness due to high cross-linking density. Here, we developed a biphasic ionic hydrogel (BIH) by integrating microgel-rich ionic reservoirs (microgel phase) into a continuous hydrogel matrix (CH phase) via hydrogen bonds. The microgel phase and CH phase of BIH work synergistically, reducing cross-linking density while maintaining the ion monomer content of the hydrogel. This synergistic structure decouples ionic storage from mechanical compliance, enabling ultrasoftness (2 kPa) and high ionic conductivity (8.55 S m–1), surpassing conventional ionic hydrogels. By tuning the microgel content, we increased the polymer network’s characteristic length, facilitating ion diffusion while maintaining structural integrity and reducing interfacial impedance. Demonstrations in real-time electromyography and mechanical motion sensing validated its potential for soft bioelectronics.
研究领域:
生物材料
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软体电子
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Matter
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2022
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IF 19.967
Xiao Wang,Xiaotong Sun,Donglin Gan,Manon Soubrier,Hsin-Yin Chiang,Liwei Yan,Yingqi Li,Junjun Li,Shuang Yu,Yang Xia,Kefeng Wang,Qiaozhen Qin,Xiaoxia Jiang,Lu Han,Taisong Pan,Chaoming Xie,Xiong Lu
Summary Brain-machine interfaces (BMIs) enable communication between the brain and external machines. However, mechanical and biological mismatches, as well as weak physical adhesion-induced shifts between rigid electronic devices and soft brain tissue, generally trigger a host immune response, affecting signal recording and reducing the lifespan of BMIs in clinics. Herein, we design a bioadhesive ultrasoft BMI based on integration of bioelectronics with a dopamine methacrylate-hybridized poly(3,4-ethylenedioxythiophene) nanoparticle (dPEDOT NP)-incorporated hydrogel with high conductivity. The hydrogel exhibits robust adhesiveness, enabling tight integration with metallic microcircuits and seamless adhesion to the brain tissue. Most importantly, the hydrogel exhibits a brain-level modulus that reduces its mechanical discrepancy with brain tissue. Meanwhile, the hydrogel possesses immune-evasive ability, which actively prevents fibrous tissue encapsulation and neuroinflammation after implantation. Consequently, the immune-evasive, bioadhesive, ultrasoft, and conductive hydrogel-integrated BMI permits long-term and accurate electroencephalographic signal acquisition and communication with minimal foreign body reaction.
研究领域:
神经科学
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生物医学工程
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材料科学
✓ 已验证
DOI
高影响因子
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