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TALANTA · 2022 · IF 6.556

Ultra-precise weak measurement-based interfacial biosensors

Lizhong Zhang,Qiang Huang,Xiaonan Zhang,Zhen Zeng,Hailong Zhang,Tian Guan,Yang Xu,Chongqi Zhou,Lingqin Meng,Gengyu Liang,Zhangyan Li,Bei Wang,Le Liu,Cuixia Guo,Yonghong He

In this study, an interfacial biosensing scheme with ultra-precision is proposed. The scheme uses weak measurement techniques to ensure ultra-high sensitivity of the sensing system while improving the stability of the system through self-referencing and pixel point averaging, thus achieving ultra-high detection accuracy of biological samples. In specific experiments, we have used the biosensor in this study to perform specific binding reaction experiments for protein A and Mouse IgG with a detection line of 2.71 ng/mL for IgG. In addition, the sensor is non-coated, simple in structure, easy to operate, and low in cost of use.

CAS / MDL: 62-31-7 77-86-1

研究领域: 生物传感器 · 生物技术 · 分析化学

✓ 已验证产品关联 DOI PubMed 高影响因子

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JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS · 2025 · IF 3

Investigation on sedimentation, magnetization, and polishing characteristics for magnetorheological shear thickening polishing fluids

Yebing Tian,Cheng Qian,Xiangyu Yuan,Kunal Arora,Guangyi Wu,Zepeng Chen,Qi Wang

Magnetorheological shear thickening polishing (MRSTP) has garnered significant attention in the field of ultra-precision polishing. However, current studies have primarily concentrated on the rheological properties of MRSTP fluids (MRSTPFs) and their application in polishing planar workpieces. The study investigated the sedimentation behavior, magnetization property of MRSTPFs, and their polishing performance on ring-shaped silicon carbide ceramic. The MRSTPFs were prepared by blending diamond particles, carbonyl iron particles, and a carrier fluid consisting of polyethylene glycol 200 and silicon dioxide. MRSTPFs with higher concentration of carrier fluid exhibited superior resistance to sedimentation. Specifically, the MRSTPFs with carrier fluid concentrations of 15 % and 20 % showed sedimentation ratios of 4 % and 2 %, respectively, after 49 days. The magnetic hysteresis loop of MRSTPFs revealed excellent magnetic stability and minimal hysteresis loss. The coercive force, remanence, and saturation magnetization were 6 Oe, 0.16 emu/g, and 43 emu/g, respectively. Furthermore, polishing experiments were conducted on ring-shaped silicon carbide ceramic using various polishing parameters, including feed rate, tool rotation speed, diamond particle size, and working gap. Under the optimal polishing parameters, the surface roughness was significantly reduced from 767 nm to 37 nm, indicating a remarkable improvement in surface quality. This study provides valuable insights into the fundamental characteristics of the MRSTPFs and highlights their significant potential for applications in ultra-precision polishing.

CAS / MDL: 112945-52-5 60676-86-0 7631-86-9

研究领域: 材料科学 · 机械工程 · 表面工程 · 流变学 · 磁性材料

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Ultra-precise weak measurement-based interfacial biosensors

Investigation on sedimentation, magnetization, and polishing characteristics for magnetorheological shear thickening polishing fluids