ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 23
·23981-23993
·
IF 2.914
Li Lincheng,Zhong Dengjie,Xu Yunlan,Zhong Nianbing
In order to improve the adsorption efficiency of the adsorbent and solve the problem of separation difficulty, a novel superparamagnetic micro-nano-bio-adsorbent (PDA/Fe 3 O 4 /BC) was prepared by in situ self-assembly of polydopamine (PDA). The results of scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared spectrometer (FT-IR), X-ray photoelectron spectrometer (XPS), and vibrating sample magnetometer (VSM) characterization showed that the size of bio-adsorbent was about 200 nm. PDA and Fe 3 O 4 modifications increased the specific surface area of adsorbent, changed the surface functional group of biochar (BC), and made the adsorbent have super-high magnetization (294.76 emu g −1 ). PDA/Fe 3 O 4 /BC was applied to treat Cr wastewater. The results show that the adsorption of Cr by PDA/Fe 3 O 4 /BC includes single-layer and multilayer adsorption. The adsorption follows the pseudo-second-order kinetic model. The adsorption is spontaneous and endothermic, and its maximum adsorption capacity and activation energy are 25.25 mg g −1 at 318 K and 23.108 kJ mol −1 , respectively. After adsorption treatment, PDA/Fe 3 O 4 /BC still possesses high magnetization (233.04 emu g −1 ). PDA/Fe 3 O 4 /BC can treat actual electroplating wastewater with Cr(VI) concentration from 20 mg L −1 to less than 0.2 mg L −1 , which met the PRC discharge standard (GB/21900-2008) of electroplating pollutants.
Graphical abstract
研究领域:
环境科学
·
环境工程
·
纳米材料
·
水污染治理
·
应用化学
✓ 已验证
DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2013
·
IF 2.072
Jun Liang,Huiru Ma,Wei Luo,Shouling Wang
Magnetite submicrospheres with an average size range of 90–490 nm were obtained by a facile polyol process. The effects of reaction conditions on the morphology and static magnetism of magnetite submicrospheres were studied when the reaction time, the concentration of component, and the types of the solvent or surfactant changed. The average size of primary crystals was controlled by changing the concentration of surfactant thus the superparamagnetism was obtained, meanwhile the average size of secondary clusters was tuned by changing the concentration of ferrous precursor FeCl 3 ·6H 2 O. The ratio of ethylene glycol and diethylene glycol , the concentration of NaAC, and the reaction time all exhibited novel effects on the morphology of magnetite submicrospheres facilitating our understanding about the synthesis mechanism. The synthesized magnetite submicrospheres were successfully used for photonic crystal .
研究领域:
材料科学
·
纳米技术
·
磁性材料
·
生物医学工程
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2016
·
IF 3.15
Pengfei Xu,Zhiwei Shen,Baolin Zhang,Jun Wang,Renhua Wu
Superparamagnetic iron oxide nanoparticles (SPIONs) as T2 contrast agents have great potential to sense calcium ion (Ca 2+ ) using magnetic resonance imaging (MRI). Here we prepared calcium-responsive SPIONs for MRI, formed by combining poly(ethylene glycol) (PEG) and polyethylenimine (PEI) coated iron oxide nanoparticle (PEI/PEG-SPIONs) contrast agents with the straightforward calcium-sensing compound EGTA (ethylene glycol tetraacetic acid). EGTA was conjugated onto PEI/PEG-SPIONs using EDC/sulfo-NHS method. EGTA-SPIONs were characterized using TEM, XPS, DSL, TGA and SQUIID. DSL results show that the SPIONs aggregate in the presence of Ca 2+ . MRI analyses indicate that the water proton T2 relaxation rates in HEPES suspensions of the EGTA-SPIONs significantly increase with the calcium concentration because the SPIONs aggregate in the presence of Ca 2+ . The T2 values decreased 25% when Ca 2+ concentration decreased from 1.2 to 0.8 mM. The aggregation of EGTA-SPIONs could be reversed by EDTA. EGTA-SPIONs have potential as smart contrast agents for Ca 2+ -sensitive MRI.
研究领域:
医学影像学
·
纳米医学
·
生物材料学
✓ 已验证
DOI
高影响因子
Journal of Biomedical Research
·
2024
·Vol. 39
·期 1
·87
·
IF 2.2
Chunming Tang,Yanling Wang,Min Wu,Zhiji Wang,Yupeng Zhou,Ya Lin,Yijun Wang,Huae Xu
Glioblastoma multiforme (GBM) is a highly aggressive and lethal brain tumor with limited treatment options. To improve therapeutic efficacy, we developed a novel multifunctional nanoplatform, GM@P(T/S), comprised of polymeric nanoparticles coated with GBM cell membranes as well as co-loaded with temozolomide (TMZ) and superparamagnetic iron oxide (SPIO) nanoparticles. The successful preparation was confirmed in terms of particle size, morphology, stability, the in vitro drug release, and cellular uptake assays. We demonstrated that GM@P(T/S) exhibited the enhanced homotypic targeting, the prolonged blood circulation, and efficient blood-brain barrier penetration in both in vitro and in vivo studies. The combination of TMZ and SPIO nanoparticles within GM@P(T/S) synergistically improved chemo-radiation therapy, leading to a reduced tumor growth, an increased survival, and minimal systemic toxicity in the orthotopic GBM mouse models. Our findings suggest that GM@P(T/S) holds a great promise as a targeted and efficient therapeutic strategy for GBM.
研究领域:
肿瘤学
·
纳米医学
·
神经科学
✓ 已验证
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 31
·32345-32359
·
IF 2.914
Yu Binglong,Wang Jie,Yang Xiaoxin,Wang Wenlong,Cai Xiulan
In this paper, we synthesized a polyglycerol(PG)-mediated superparamagnetic graphene oxide nanocomposite called MGON, consisting of PG-modified superparamagnetic iron oxide nanoparticles (SPION) covalently bonded to PG-functionalized graphene oxide (GO). MGON exhibits better dispersibility and colloidal stability in aqueous solution than the magnetic graphene oxide reported in the literature. The physicochemical properties of MGON were analyzed by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), and UV-vis spectroscopy. Applied to the adsorption of tetracycline (TC) in aqueous solution as an adsorbent, the MGON showed excellent adsorption performance with the maximum adsorption capacity of 684.93 mg/g at 298 K. Adsorption kinetics and isotherm results indicate that the adsorption process conforms to the pseudo-second-order kinetics and Langmuir isotherm models. Adsorption thermodynamics has confirmed that the adsorption process of TC on MGON is spontaneous and endothermic. With the increase of temperature, the adsorption capacity of MGON increases continuously, and the adsorption capacity of MGON is the largest when the pH value is 7. Furthermore, the π-π and cation-π interaction, amidation reaction, and hydrogen bonding can be used to explain the adsorption mechanism of TC on MGON. Desorption and regeneration experiments showed that MGON still had 67.65% regenerative performance after five cycles. Hence, MGON is a promising adsorbent in the removal of tetracycline from wastewater.
研究领域:
环境科学
·
纳米材料学
·
污染物吸附
·
水污染治理
·
环境功能材料
✓ 已验证
DOI
高影响因子
Polymer Chemistry
·
2014
·Vol. 5
·期 14
·4332-4338
·
IF 5.368
Feng Wang,Liyan Huang,Jun Li,Lina Lin,Zhengping Liu,Zhaoxia Dong
Well-defined superparamagnetic and conductive Fe3O4/polyaniline (PANI) hollow spheres were fabricated using positively charged polystyrene (PS) spheres as templates. The negatively charged Fe3O4 particles, which were decorated by citric acid, can be attached onto the surface of the PS spheres via electrostatic interaction. Subsequently, the PANI layer was coated onto the PS/Fe3O4 templates by in situ chemical oxidative polymerization. Finally, removal of the PS core by dissolving with tetrahydrofuran provided the electromagnetic hollow spheres. Morphologies and compositions of Fe3O4/PANI hollow spheres were investigated by using SEM, TEM, FTIR and XRD. Magnetic analysis demonstrates that the synthesized composite spheres possess the characteristic of superparamagnetism and the saturation magnetization value is 26.2 emu g−1. Batch adsorption shows that the Fe3O4/PANI hollow spheres exhibit high uptake property of Pb2+ in aqueous solution. The adsorption kinetics follows the mechanism of pseudo-second-order kinetics and the sorption agrees well with the Langmuir isotherm.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2018
·
IF 5.08
Huikang Yang,Nianhua Wang,Lei Mo,Mei Wu,Ruimeng Yang,Xiangdong Xu,Yugang Huang,Jiantao Lin,Li-Ming Zhang,Xinqing Jiang
Tumor-targeted multifunctional nanocarriers play an important role in tumor diagnosis and treatment. Herein, disulfide bonds linked amphiphilic hyaluronan-SS-poly(ε-caprolactone) diblock copolymers (HA-SS-PCL) were synthesized and studied as theranostic nanocarriers for tumor diagnosis and treatment. The chemical structure of HA-SS-PCL was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance ( 1 H NMR). The self-assembling behavior of the HA-SS-PCL into GSH-responsive micelles and their degradation were characterized by fluorescence spectroscopy, dynamic light scattering (DLS) and transmission electron microscopy (TEM). Theranostic nanocarriers encapsulating doxorubicin (DOX) and superparamagnetic iron oxide (SPIO) were formed via a dialysis. In vitro drug release results suggested that the HA-SS-PCL micelles possessed reductant-triggered doxorubicin release ability, which was confirmed by 100% of DOX release from HA-SS-PCL micelles within 12 h under 10 mM of glutathione (GSH), whereas about 40% of DOX was released under non-reductive condition within 24 h. Both flow cytometry and confocal laser scanning microscopy (CLSM) analysis revealed that the HA-SS-PCL micelles loaded with DOX were internalized in HepG2 cell via a receptor mediated mechanism between hyaluronan and the CD44 receptor. Furthermore, the MTT assay and cell apoptosis analysis revealed that the DOX-loaded HA-SS-PCL micelles exhibited pronounced antitumor ability towards HepG2 cells compared with that of the reduction-insensitive HA-PCL micelles at the same DOX dosage. The r 2 relaxivity value of the DOX/SPIO loaded HA-SS-PCL micelles was up to 221.2 mM −1 s −1 (Fe). Thus, the obtained HA-SS-PCL block copolymers demonstrate promising potential as tumor targeting theranostic nanocarriers in the field of tumor diagnosis and treatment.
研究领域:
生物材料
·
肿瘤学
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Polymer Chemistry
·
2012
·Vol. 4
·期 5
·1425-1429
·
IF 5.321
Xinjia Yang,Buyi Li,Irfan Majeed,Liyun Liang,Xuejun Long,Bien Tan
Magnetic microporous polymer nanoparticles (MMPNs) with high surface area and superparamagnetic properties have been designed and synthesized successfully. Their application in removing toxic organic compound by adsorption and magnetic separation have been proved. The MMPNs were also evaluated for their ability to uptake and control the release of ibuprofen.
研究领域:
材料科学
·
纳米医学
·
药物递送
·
环境修复
·
生物材料
·
药剂学
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2015
·Vol. 15
·期 6
·4608-4618
·
IF 1.556
Cui Qinmin,Zhu Shudi,Yan Yingjie,Ye Quanlin,Ziener Ulrich,Cao Zhihai
In the present study, superparamagnetic Fe3O4/poly(N-isopropyl acrylamide) nanocomposites were synthesized by one-step inverse miniemulsion copolymerization of N-isopropyl acrylamide and N,N'-methylene diacrylamide. The loading of Fe3O4 nanoparticles
in the nanocomposites was 27 wt%, and the saturation moment of the nanocomposites was 12.4 emu · g−1. Fe3O4 nanoparticles were prepared through a coprecipitation method. The amount of stabilizer (poly(acrylic acid)) significantly influenced the
size and size distribution of the Fe3O4 nanoparticles, and, therefore, their magnetic properties. Superparamagnetism of the Fe3O4 nanoparticles was preserved in the nanocomposites. The effects of synthetic parameters on the particle properties, namely
surfactant loading, concentration of ferrofluid, type of lipophobe and initiator, and amount of cross-linker were investigated. Nanocomposites of Fe3O4/poly(N-isopropyl acrylamide) displayed a guava-like morphology, which they could retain after being redispersed
in polar solvents.
研究领域:
材料科学
·
纳米技术
·
化学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2014
·Vol. 49
·期 20
·7181-7191
·
IF 2.305
Mu Bin,Zhang Wenbo,Wang Aiqin
A novel superparamagnetic gold/halloysite nanotubes/Fe 3 O 4 (Au/HNTs/Fe 3 O 4 ) nanocomposite with coaxial structure was designed and fabricated by selective decoration of the inner lumen and the external wall of halloysite nanotubes (HNTs) based on the difference inside/outside surface charges. The structure and composition of Au/HNTs/Fe 3 O 4 were characterized by transmission electron microscope, powder X-ray diffraction, and X-ray fluorescence. The results indicated that Au nanorods selectively generated within the lumen of HNTs, while Fe 3 O 4 nanoparticles uniformly deposited on the external wall. It was particularly worth mentioning that the structure of HNTs was not destroyed in the preparation process of Au/HNTs/Fe 3 O 4 nanocomposites. The catalytic activity of the as-prepared Au/HNTs/Fe 3 O 4 was investigated for the reduction of 4-nitrophenol in the presence of NaBH 4 . The Au/HNTs/Fe 3 O 4 nanocomposites exhibited excellent catalytic activity and cycling stability according to the kinetic data of the catalytic reduction reaction. In addition, the Au/HNTs/Fe 3 O 4 catalysts can be easily manipulated by an external magnetic field for recycling.
研究领域:
纳米材料学
·
催化化学
·
无机化学
·
环境功能材料
·
纳米复合材料
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2014
·
IF 2.538
Songbo Xie,Baolin Zhang,Lei Wang,Jun Wang,Xuan Li,Gao Yang,Fabao Gao
PEG and PEG/PEI modified superparamagnetic iron oxide nanoparticles (SPIONs) were synthesized by the thermal decomposition of iron (III) acetylacetonate (Fe(acac) 3 ) in poly (ethylene glycol) (PEG) containing poly (ethylene imine) (PEI) (0 or 0.3 g). PEG/PEI-SPIONs were coated with Tween 80 (PEG/PEI/Tween 80-SPIONs). Fourier transform infrared spectroscopy (FTIR) analyses indicated that PEG , PEG/PEI and PEG/PEI/Tween 80 were attached to the surfaces of the SPIONs. The PEG-SPIONs, PEG/PEI-SPIONs and PEG/PEI/Tween 80-SPIONs performed excellent colloidal stability in the phosphate buffered saline (PBS), and in deionized water with the mean hydrodynamic sizes of 19.5, 21.0, 24.0 nm and the zeta potentials of -5.0, 35.0, 19.0 mV, respectively. All the SPIONs showed low cytotoxicity assessed by the MTT assay. In vivo magnetic resonance imaging (MRI) of the Kunming (KM) mouse brains were performed, the PEG-SPIONs, PEG/PEI-SPIONs and PEG/PEI/Tween 80-SPIONs exhibited vascular imaging effects in bulbus olfactorius, frontal cortex, temporal, thalamus and brain stem of the mouse brains after 24 h intravenous injection of the nanoparticles . The SPIONs have potentials as MRI contrast agents in the mouse brains.
研究领域:
生物医学工程
·
纳米医学
·
影像学
✓ 已验证
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2014
·
IF 2.736
Jingting Zhou,Huanbao Fa,Wei Yin,Jin Zhang,Changjun Hou,Danqun Huo,Dong Zhang,Haifeng Zhang
Superparamagnetic iron oxide nanoparticles (SPIONs) have been proposed for use in magnetic resonance imaging as versatile ultra-sensitive nanoprobes for Alzheimer's disease imaging. In this work, we synthetized an efficient contrast agent of Alzheimer's disease using 1,1-dicyano-2-[6-(dimethylamino)naphthalene-2-yl]propene (DDNP) carboxyl derivative to functionalize the surface of SPIONs. The DDNP-SPIONs are prepared by conjugating DDNP carboxyl derivative to oleic acid-treated SPIONs through ligand exchange. The structure, size distribution and magnetic property were identified by IR, TGA–DTA, XRD, TEM, Zetasizer Nano and VSM. TEM and Zetasizer Nano observations indicated that the DDNP-SPIONs are relatively mono-dispersed spherical distribution with an average size of 11.7 nm. The DDNP-SPIONs were then further analyzed for their MRI relaxation properties using MR imaging and demonstrated high T 2 relaxivity of 140.57 s − 1 Fe mM − 1 , and the vitro experiment that DDNP-SPIONs binding to β-Amyloid aggregates were then investigated by fluorophotometry, the results showed that the combination had induced the fluorescence enhancement of the DDNP-SPIONs and displayed tremendous promise for use as a contrast agent of Alzheimer's disease in MRI.
研究领域:
纳米技术
·
生物医学成像
·
神经退行性疾病
·
磁共振成像
·
生物偶联化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）