ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2025
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IF 6.1
Fan Gao,Lingyun Zhu,Fan Zhang,Meng Li,Hairong Lian,Sen Feng,Xinfeng Cheng,Xianling Xiang
Metformin (MET) and its metabolite guanylurea (GUA) are prevalent in aquatic environments, raising concerns about their potential risks to aquatic organisms. However, the toxicity of these compounds through different exposure routes has not been reported. This study evaluated the effects of MET and GUA on the growth of the green algae Tetradesmus obliquus and on life table parameters of the freshwater rotifer Brachionus calyciflorus through various exposure routes, including waterborne, foodborne, and combined waterborne + foodborne. Our results indicated that both MET and GUA, at concentrations of 1 mg/L and 100 mg/L, inhibited algae growth, with GUA causing greater stress than MET. Additionally, compared to waterborne exposure, foodborne and combined waterborne + foodborne exposures of MET and GUA at these concentrations significantly decreased the net reproductive rate (R 0 ), intrinsic rate of population increase (r m ), and life expectancy (e 0 ) of B. calyciflorus . Notably, the impact of exposure routes on the life table parameters of B. calyciflorus was generally greater than the impact of exposure concentrations. Therefore, previous studies focusing solely on waterborne exposure may have underestimated the toxicity of MET and GUA.
研究领域:
环境科学
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2023
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IF 9.8
Fan Gao,Hao Wen,Sen Feng,Meng Li,Lingyun Zhu,Yongzhi Zhang,Yilong Xi,Xianling Xiang
The emerging contaminants metformin (MET) and its degradation product guanylurea (GUA) are released into aquatic environments through wastewater treatment plants (WWTPs). Thus, the environmental risks of wastewater with more treatments may be underestimated due to the lower effect concentration of GUA and the higher detected concentration of GUA in treated wastewater in comparison with MET. In this study, we aimed to investigate the combined toxicity mode of MET and GUA to Brachionus calyciflorus by simulating the degrees of wastewater treatments through adjustments to the ratio of MET and GUA in medium. The results showed that the 24 h-LC 50 of MET, GUA, their mixtures of equal concentrations and the mixtures of equal toxic units to B. calyciflorus were 907.44, 544.53, 1185.82 and 940.52 mg/L, respectively, demonstrating GUA is significantly more toxic than MET. An antagonistic interaction between MET and GUA was found in mixture toxicity assessments. Compared with the control, MET treatments only significantly affected the intrinsic rate of population increase of rotifers (r m ), while all life-table parameters were significantly affected by GUA. In addition, at medium and high concentrations (120 and 600 μmol/L), the net reproductive rate (R 0 ) and r m of rotifers under GUA were significantly lower than those under MET. Notably, increased proportion of GUA relative to MET in binary-mixture treatments resulted in increased survival risk and reduced fecundity of rotifers. Moreover, the responses of population dynamics to exposures of MET and GUA were mainly attributed to the reproduction of rotifer, indicating that an improved wastewater treatment process is necessary to protect aquatic ecosystems . The study highlights the importance of considering the combined toxicity of emerging contaminants and degradation product in environmental risk assessment , especially the unintentional transformations of parent compound in treated wastewater.
研究领域:
环境科学
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PLANKTON RESEARCH
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2024
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IF 1.9
Bian Shijun,Niu Cuijuan
Maternal effect plays important role in adaptive evolution and population dynamics. Methylparaben (Mep) is a common organic pollutant exerting diverse impacts on aquatic organisms. However, the impact of maternal Mep exposure on offspring remains poorly understood. This study was designed to explore whether maternal Mep exposure can affect the offspring’s population performance, either by amictic mothers in parthenogenesis phase, or by mictic mothers in sexual reproduction phase of the rotifer Brachionus calyciflorus. Here, we exposed either amictic or mictic mothers from one clonal laboratory population to 20 mg/L Mep (T environment) until the offspring or resting eggs were collected. A parallel control group without Mep (C environment) was also set. Thereafter, offspring from amictic mothers or stem female from resting eggs of mictic mothers were treated similarly in T or C environment. Population growth, life history traits and antioxidant indices of the offspring were examined. The results demonstrated that maternal Mep exposure inhibited population performance of offspring in both life history phases, while the negative effects were markedly buffered in sexual reproduction phase. This study clarifies toxicity of Mep on rotifers and highlights the different response patterns of maternal Mep exposure in different life history phase.
研究领域:
生态毒理学
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环境科学
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动物学
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2024
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IF 8.1
Qingqing Yu,Gongyuan Wang,Zhihao Shao,Yunfei Sun,Zhou Yang
The increasing use of ultraviolet filters has become an emerging contaminant on the coast, posing potential ecological risks. Rotifers are essential components of marine ecosystems , serving as an association between primary producers and higher-level consumers. These organisms frequently encounter ultraviolet filters in coastal waters. This study aimed to assess the comprehensive effects of organic ultraviolet filters, specifically 2-ethylhexyl-4-methoxycinnamate (EHMC), and inorganic ultraviolet filters, namely, titanium dioxide nanoparticles (TiO 2 NPs), on the rotifer Brachionus plicatilis . We exposed B. plicatilis to multiple combinations of different concentrations of EHMC and TiO 2 NPs to observe changes in life history parameters and the expression of genes related to reproduction and antioxidant responses. Our findings indicated that increased EHMC concentrations significantly delayed the age at first reproduction, reduced the total offspring, and led to considerable alterations in the expression of genes associated with reproduction and stress. Exposure to TiO 2 NPs resulted in earlier reproduction and decreased total offspring, although these changes were not synchronised in gene expression. The two ultraviolet filters had a significant interaction on the age at first reproduction and the total offspring of rotifer, with these interactions extending to the first generation. This research offers new insights into the comprehensive effects of different types of ultraviolet filters on rotifers by examining life history parameters and gene expression related to reproduction and stress, highlighting the importance of understanding the impacts of sunscreen products on zooplankton health.
研究领域:
生态毒理学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
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2023
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IF 7.7
Zihang Ma,Zuhan Ge,Kexuan Liu,Cong Wang,Tao Wu,Jibiao Zhang
In this study, calcium peroxide (CaO 2 ) was added to two types of water to remove turbidity . The effects of CaO 2 on water quality, Ca content and microbial communities were also examined. The results showed that CaO 2 significantly improved the transparency of highly turbid water induced by algae. Compared with the control group, 5, 10, and 20 mg/L CaO 2 reduced the turbidity by 56.80%, 81.66%, and 82.54%, respectively. Considering the actual effect and cost, 10 mg/L CaO 2 was the recommended dosage. Furthermore, the addition of CaO 2 increased the degree of humification in the water and Ca content in the sediment. However, the addition of CaO 2 did not significantly increase the concentration of Ca 2+ in the water. Additionally, CaO 2 first decreased the richness and diversity of the bacterial and fungal communities. However, this effect gradually disappeared over time. The abundance of cyanobacteria decreased to 0 after 168 h. Actinobacteria and Compilobacteria were also inhibited by CaO 2 . At the genus level, Flavobacterium , Sphingomonas , Pseudomonas , and Limnohabitans , which occupied key nodes, were tolerant to CaO 2 , and CaO 2 had only a minor impact on the microbial ecological networks. Moreover, the eukaryotic rotifer community was destroyed. CaO 2 increased the abundance of chemotrophic heterotrophic functional groups but decreased that of the functional groups. These findings provide guidance for the use of CaO 2 to improve water turbidity and water ecological restoration.
研究领域:
环境科学
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水处理
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微生物学
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生态学
✓ 已验证
DOI
高影响因子
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