Building Simulation
·
2020
·Vol. 13
·期 4
·873-886
·
IF 2.472
Xia Tongling,Bian Ye,Shi Shanshan,Zhang Li,Chen Chun
When the outdoor PM 2.5 pollution is severe, if the windows are open, the occupants tend to be exposed to higher indoor PM 2.5 of outdoor origin. However, if the windows are closed, the ventilation rate tends to be insufficient for removing air pollutants generated indoors. Opening windows with the use of nanofiber window screens can be an alternative strategy that can balance between indoor PM 2.5 of outdoor origin and ventilation rate. This study fabricated a number of nanofiber window screens and conducted a series of experiments in a laboratory setup to measure the PM 2.5 removal efficiency and pressure drop with different window opening angles. A simple model was then developed for predicting the pressure drop, and the measured data was used to validate the model. Finally, the measured data and the validated model were used for two application cases. In the natural ventilation case, the use of nanofiber window screens can effectively reduce indoor PM 2.5 of outdoor origin, and the ventilation rate can be improved when compared with infiltration in the house. However, the nanofiber window screens could not reduce the PM 2.5 level in the kitchen with a range hood when the cooking PM 2.5 emission rate was high.
研究领域:
环境科学
·
公共卫生
✓ 已验证
产品关联
DOI
高影响因子
PROCESS BIOCHEMISTRY
·
2024
·
IF 3.7
Shaoyang Zhang,Guorong Zhu,Zhixiang Pan,Yi Wei,Zuoming Nie,Qing Sheng,Zhongyi Yang
L-threo-methylsulonylphenylserine (L-threo-MSPS) is a crucial intermediate in florphenicol and thiamphenicol synthesis. L-threo-MSPS can be synthesized from L-threonine and p-methylsulfonylbenzaldehyde (p-MSBA) chiral selectively under the catalyse of L-threonine transaldolase . However, the byproduct acetaldehyde formed during the reaction process severely hinders the biosynthesis of high-quality L-threo-MSPS. The accumulated acetaldehyde reacts with L-thero-MSPS and L-threonine to form N-derivatives, and the activity of L-threonine transaldolase decreases to 14.10% even when the concentration of acetaldehyde is as low as 0.5 g/L. The acetaldehyde could be removed by aeration, and the removal efficiency is closely related to the aeration conditions, which was described by the volumetric oxygen transfer coefficient k L a in this paper. Regular aeration through pipes cannot provide enough aeration efficiency, and filters or sintered rods were used to increase the k L a value during the reaction. The residual concentration of acetaldehyde depended on the balance between the formation and removal speed of acetaldehyde. When the optimal enzyme concentration was applied and the k L a value of 5.5 min -1 , the L-threo-MSPS concentration reached 293.28 mM in a 1-L reaction, and the highest conversion reached 90.03%. The need of coenzyme NAD + was cut off in this method, and only one enzyme was applied. Consequently, the reaction was simpler and easier to control.
研究领域:
生物化学
·
制药工程
✓ 已验证
产品关联
DOI
高影响因子
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
·
2015
·
IF 0.541
N. N. Jiang,T. Xing,P. Wang,C. Xie,X. L. Xu
Effects of water-misting sprays with forced ventilation after transport during summer on meat quality, stress parameters, glycolytic potential and microstructures of muscle in broilers were investigated. A total of 105 mixed-sex Arbor Acres broilers were divided into three treatment groups: i) 45-min transport without rest (T group), ii) 45-min transport with 1-h rest (TR group), iii) 45-min transport with 15-min water-misting sprays with forced ventilation and 45-min rest (TWFR group). The results showed the TWFR group significantly increased (p<0.05) initial muscle pH (pH i ) and ultimate pH (pH u ) and significantly reduced L* (p<0.05), drip loss, cook loss, creatine kinase, lactate dehydrogenase activity, plasma glucose content, lactate and glycolytic potential when compared with other groups. Microstructure of the muscle from TWFR group broilers under light microscopy showed smaller intercellular spaces among muscle fibers and bundles compared with T group. In conclusion this study indicated water-misting sprays with forced ventilation after transport could relieve the stress caused by transport under high temperature, which was favorable for the broilers’ welfare. Furthermore, water-misting sprays with forced ventilation after transport slowed down the postmortem glycolysis rate and inhibited the occurrence of PSE-like meat in broilers. Although rest after transport could also improve the meat quality, the effect was not as significant as water-misting sprays with forced ventilation after transport.
研究领域:
畜牧学
·
动物福利
·
食品科学
✓ 已验证
DOI
PubMed
高影响因子
ENVIRONMENT INTERNATIONAL
·
2019
·
IF 7.943
Guodi Zheng,Bao Yu,Yuewei Wang,Chuang Ma,Tongbin Chen
Triclosan (TCS) is widely used as an antibacterial disinfectant in personal care products, especially in rapidly-urbanizing countries, such as China. Almost all TCS enters wastewater treatment plants (WWTPs), but the fate of the TCS in the WWTPs is unclear. TCS may be present in sewage sludge or in effluent, and the discharge of TCS into an ecosystem can pose environmental risks. In the present study, influent, effluent, and sewage sludge were collected from four typical urban WWTPs, and the fate of TCS in the plants was investigated. The study was conducted in Zhengzhou, a city in the middle reaches of the Yellow River in China. The sewage sludge was used for aerobic composting to study the influences of different ventilation treatments on the biodegradation effects of TCS and the changes in the microbial community during the composting process. The results showed that the mean concentration of TCS in the influent of the four typical WWTPs was 397.1 ng/L. The mean level of TCS in the effluent was 8.0 ng/L. The mean concentration of TCS in the sewage sludge was 814.4 ng/g. For the four WWTPs, the percentages of TCS removal were 97.6% (Nansanhuan), 97.6% (Xinzheng), 98.8% (Wulongkou), and 97.9% (Chenyu), respectively. The sewage sludge enrichment rates for TCS ranged between 36.4% and 49%. Therefore, there is a need to focus on the environmental risks from sewage sludge. During aerobic composting, the TCS was effectively degraded under three ventilation strategies. Thus, improved ventilation could enhance the degradation rate of TCS. Moreover, TCS degradation occurred in the mesophilic period and in the early stage of the thermophilic phase period. Finally, the degradation rates of TCS in sewage sludge samples composted with low-, medium-, and high-ventilation treatments were 48.1%, 59.0%, and 59.5%, respectively. Thus, high ventilation could provide enough oxygen for the pile and enhanced microorganism activity, benefiting the degradation of TCS. In addition, the microbial communities change during the composting process, and a diversity index of the changes can help explain the composting process.
研究领域:
环境科学
·
微生物学
✓ 已验证
DOI
PubMed
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Shanshan Wu,Dingwu Zhang,Siyi Hu,Cunyu Li,Zhanbo Dong,Yurong Hu,Fangyuan Fan,Jianhui Ye,Xinqiang Zheng,Yuerong Liang,Liaoyuan Yu,Jianliang Lu
Lack of optimal sealed yellowing (SY) technique and suitable tea cultivars limits the yield and quality improvement of the Pingyang Huangtang (PYHT) tea. In this study, the effect of SY temperature, relative humidity (RH) and ventilation operation on the PYHT quality had been investigated. Results showed total sensory score was significantly influenced by SY temperature and RH, and optimal PYHT quality could be achieved when SY was performed at 60 °C, 70 % RH for 10 h with 2 ventilation operation. Quality formation of PYHT was mainly associated with degradation of chlorophylls, fluctuation of volatile with different odor notes, and decrease in level of galloylated catechins and the ratio of total polyphenols to amino acids. The quality of tea made from the shoots of ‘Zhenong 801’, ‘Zhongcha 108’, ‘Jiukengzao’ and ‘5–21’ was higher than that of the commonly used cultivar ‘Pingyang Tezao’, therefore, these cultivars were recommended to apply in PYHT industry.
研究领域:
食品科学
·
茶叶加工学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2017
·Vol. 33
·期 6
·965-970
·
IF 1.024
Liu Shankui,Liu Pengcheng,Niu Ruyue,Wang Shuang,Li Jinping
Flower-like Co 3 O 4 hierarchical microspheres composed of self-assembled porous nanoplates were prepared by employing Pluronic F127 block-copolymer as template. The samples were characterized by powder X-ray diffraction(PXRD), scanning/transmission electron microscopy(SEM/TEM), and nitrogen adsorption-desorption at 77 K. The results show that the catalytic activity of Co 3 O 4 nanoflowers for the combustion of ventilation air methane is higher than that of commercial Co 3 O 4 . The superior catalytic performance of this material can be related to its dominantly exposed {112} crystal planes and higher content of surface Co 3+ .
研究领域:
材料科学
·
环境催化
✓ 已验证
DOI
高影响因子
FUEL
·
2022
·
IF 8.035
Yuzeng Zheng,Fashe Li,Huicong Zhang,Shuang Wang,Zhongjin Zhao,Wenchao Wang,Renyi Chen
The effects of light, ventilation and antioxidant on biodiesel performance and the corresponding influence mechanisms are investigated during long-term storage. The biodiesel exhibits slow autoxidation and its physical/chemical properties change during storage. Light and ventilation conditions can accelerate the oxidation of biodiesel, thereby aggravating its degradation. During the autoxidation process of biodiesel, the grinding spot diameter firstly decreases from 165.01 μm to 131.45 μm and then increases to 362.5 μm, similar to the shape of a fishhook. During the initial storage stage, the fatty acid methyl ester in biodiesel is decomposed into carboxylic acid and small molecular substances such as aldehydes and ketones, thereby improving the lubricity of biodiesel and reducing the grinding spot diameter. After long-term storage, insoluble resins and sediments are generated, causing an increase in the grinding spot diameter. Specifically, the kinematic viscosity of biodiesel is increased to 4.407 mm 2 /s even under dark and sealed storage conditions.
研究领域:
化学工程
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
·
2025
·
IF 1.3
Junying Wu,Qiong An,Zhenggen Liao,Yulin Feng,Wuliang Yang,Haifang Chen,Wugang Zhang
Hyperuricemia arises from an imbalance between uric acid production and excretion, resulting in elevated systemic uric acid levels. Consequently, therapeutic strategies targeting both production and excretion pathways offer a promising approach for managing hyperuricemia. TongFengTangSan has been frequently utilized as the Tibetan prescription in treating hyperuricemia or gout, and its anti-hyperuricemia effect has been confirmed in our previous study. However, the urate-lowering components still remain unclear. Therefore, an integrative strategy was constructed to screen potential urate-lowering components from TongFengTangSan by combination with affinity ultrafiltration, molecular docking and in vitro validation. In the present study, the main active fraction of TongFengTangSan with xanthine oxidase inhibitory effect was screened out by xanthine oxidase inhibitory assay. The potential ligands in main active fraction were identified by affinity ultrafiltration experiment combined with enzyme channel blocking technology and explored by ultra-high performance liquid chromatography-linear ion trap-Orbitrap mass spectrometry. Then, the screened ligands were further validated by in vitro xanthine oxidase inhibitory assay and molecular docking technique. Furthermore, the regulation effect on uric acid transporters of xanthine oxidase inhibitors was further evaluated by the over-expression of uric acid transporters in uric acid stimulated human Kidney-2 cell model by Western blot assay. In this study, the 60% ethanol-eluted fraction from the ethanol extract of TongFengTangSan was confirmed as the main fraction of TongFengTangSan with the best xanthine oxidase inhibitory effect. Three potential xanthine oxidase inhibitors were screened out from the 60% ethanol-eluted fraction, including 1,3,6-trigalloylglucose, 1,2,3,6-tetragalloylglucose and 1,2,3,4,6-pentagalloylglucose. Half maximal inhibitory concentration values of 1,3,6-trigalloylglucose, 1,2,3,6-tetragalloylglucose and 1,2,3,4,6-pentagalloylglucose for xanthine oxidase were 54.46, 15.91, 6.58 μg/mL, respectively. 1,3,6-trigalloylglucose, 1,2,3,6-tetragalloylglucose and 1,2,3,4,6-pentagalloylglucose were identified as mixed-type xanthine oxidase inhibitors. Additionally, these compounds demonstrated inhibitory effects on urate transporters 1 and glucose transporter 9. The combination strategy is suitable for screening active components with dual properties of inhibiting uric acid production and promoting uric acid excretion. 1,3,6-trigalloylglucose,1,2,3,6-tetragalloylglucose and 1,2,3,4,6-pentagalloylglucose were identified as a potential urate-lowering drug and exhibited dual-target characteristics in uric acid metabolism.
研究领域:
药理学
·
代谢组学
·
药物化学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Environmental Science and Technology
·
2023
·Vol. 20
·期 12
·13119-13142
·
IF 3.1
Li W.,Du Z.,Wu Z.,Yu M.
In the context of epidemic normalization, it is particularly important to explore environmental health from the perspective of adaptation of patient pathological characteristics to achieve sustainable goals. Although recent studies have confirmed the effects of ventilation and sound on human health and revealed that improvement in the quality of patient recovery can be achieved by controlling the material exchange between people and the environment, it remains unclear in terms of the mutual drivers of intangible material (ventilation and sound) and patient recovery quality. This study establishes a link between the physical environment and the quality of rehabilitation by reporting on the ventilation and noise levels at a rehabilitation facility for people with cognitive disorders. Second, a successful design optimization technique based on the adaption of pathological traits is suggested. The Centre fails to fulfil the ventilation and acoustic criteria for indoor comfort, according to the findings of the real testing. The study procedure demonstrates that (1) enhancing the space's openness to unblock the airflow can only have its effect maximised if the layout is taken into account to accommodate the wind direction.; (2) the spatial scale is not the only factor affecting the sound quality of the environment; and (3) increasing the openness of the area can improve the quality of sound transmission and reduce noise in the area, but at the same time, it will have some impact on other areas.
研究领域:
公共卫生
·
环境医学
·
康复医学
·
建筑环境与健康
·
临床环境科学
·
老年医学
·
生物医学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）