JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2021
·
IF 2.694
Yangyi Huang,Yuning Zhang,Haoran Liu,Weiping Luo
In this study, the solubilities of isophthalic acid (IPA) in N-methylformamide (NMFM), N-methylformanilide (NMFL), propanoic acid (PA), sulfolane, and dimethyl sulfoxide (DMSO) and m-toluic acid (m-TA) in acetone, cyclohexanone (CYC), 1-methyl-2-pyrrolidinone, NMFM, NMFL, N,N-dimethylformamide, PA, sulfolane, and DMSO were determined by the dynamic laser method at atmospheric pressure (101.2 kPa), and the solubility ratios between IPA and m-TA in different solvents were calculated. The temperature range of the experiment was between 290.15 and 348.15 K, in which the solubilities of IPA and m-TA in selected solvents were positively correlated with temperature. The maximum ratio between the mole fraction of solubilities of m-TA and IPA was in CYC and ranged from 68 to 84 for the temperature range under study. The experimental data were correlated by the Apelblat model, the Buchowski–Ksiazczak λh model, and the modified nonrandom two-liquid (NRTL) activity coefficient model.
研究领域:
化学
·
物理化学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Shengnan Hu,Hanzhu Kong,Yuting Sun,Ronghui Wu,Jing Xu,Ming Guo
Biological enzyme-driven degradation of environmental pollutants has attracted widespread attention because it is ecofriendly and highly efficient. Immobilized enzyme technology has emerged as a promising technique in enzymology that addresses the limitations associated with free enzymes. Traditional solid-loaded enzyme substrates are often affected by blockages and restricted substrate accessibility. In this study, we synthesized an efficient heterogeneous pepsin catalyst, named PEP@M-MIL100(Fe), by covalently combining carboxylated ferrite structural expanded metal–organic frameworks with pepsin. This catalyst demonstrated excellent environmental adaptability and remarkable catalytic degradation capabilities. Notably, it rapidly degraded the persistent microplastic pollutant diisononyl phthalate (DINP) within just 150 min, with a removal efficiency of up to 95.88%. Impressively, even after 10 consecutive uses, the catalyst maintained its high performance. We proposed an innovative steady-state heterogeneous enzyme-catalyzed degradation mechanism, i.e., diffusion (D)–absorption (A)–binding (B)–reaction (R)–degradation (D)–link mechanism, which emphasizes the influence of substrate diffusion rates in this process. This work presents the first successful application of pepsin to DINP degradation and offers a sustainable and effective approach for addressing contemporary pollution challenges.
研究领域:
环境科学
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酶学
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材料科学
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污染控制
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Ning Lu,Junzhuo Cai,Baoling Niu,Ye Zhou,Guohua Zhao
Endowing traditional photocatalysis with selectivity for a class of characteristic pollutants is important in environmental science. Using PAEs-TiO 2 as a selective photocatalyst, 302.5 μg L −1 of 11 phthalic esters (PAEs) were preferentially removed to 4.94 μg L −1 in the presence of 10 mg L −1 of natural organic matter via specific hydrogen bonds or cation-π interactions. Further, degradation of PAEs is a lower risk pathway for PAEs-TiO 2 . The in-situ photocatalytic electron paramagnetic resonance initially revealed that PAEs-TiO 2 facilitated the ring opening and mineralization of PAEs, resulting in nearly 100 % detoxification. In actual wastewater, PAEs were not detected after treatment with PAEs-TiO 2 . Further, the energy cost was reduced by 48.1 %, reaching discharge standard. This study offers new sights into selective photocatalysis of a class of pollutants with similar molecular structure.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
Toxicology Research
·
2022
·Vol. 11
·期 5
·863-871
·
IF 2.68
Xia Ling-Zi,Jiang Ming-Zhe,Liu Li-Lan,Wu Yi,Zhang Yi-Lin,Yang Li-Xia,Shen Xin-Yue,Zhang Qiu-Yu,Lin Min,Gao Hai-Tao
Humans are increasingly exposed to ubiquitous phthalates (PEs), e.g. butyl benzyl phthalate (BBP), dibutyl phthalate (DBP), and di(2-ethylhexyl) phthalate (DEHP), which are widely used plasticizers in polymer products. This study was aimed to investigate the effect of phytochemical quercetin (Que) on hepatotoxicity caused by the mixture of the 3 commonly used PEs (MPEs), and further to explore the underlying mechanism. Forty male Sprague–Dawley rats were randomly divided into control group, MPEs group, and MPEs combined Que at Low-, Median-, and High-dose groups; rats in MPEs group were orally administered with 900 mg/kg/d MPEs, whereas rats in MPEs combined Que groups were simultaneously treated with 900 mg/kg/d MPEs and respectively 10, 30, and 90 mg/kg/d Que. The intervention last 30 days. Compared with control group, serum ALT, AST, LDH and AKP, and hepatic MDA, SOD, CAT and GPx were significantly increased, whereas, serum albumin and total protein were significantly decreased in MPEs group (P < 0.05); hepatic histopathological observation showed numerous inflammatory cells infiltration, hepatocyte ballooning degeneration, and numerous residual erythrocytes in the central vein in MPEs group. Western-blot analysis showed that hepatic Keap1 was downregulated, whereas Nrf2 and HO-1 were upregulated in MPEs group (P < 0.05). However, the alterations of these parameters were alleviated in MPEs combined Que at Median- and High-dose groups. The results indicated that MPEs-induced hepatic oxidative stress, and caused hepatic injuries; whereas, Que inhibited MPEs’ hepatotoxicity, which might relate to Que’s ability of quenching free radicals directly, and restored the regulation of Nrf2 signaling pathway.
研究领域:
毒理学
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药理学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Yinghua Yan,Yujie Lu,Baichun Wang,Yiqian Gao,Lingling Zhao,Hongze Liang,Dapeng Wu
The development of covalent organic framework (COF)-derived materials with additional functions and applications is highly desired. In this work, a unique COF-functionalized hydrophilic magnetic nanosphere (Fe3O4@PDA@TbBd) with Fe3O4 as a magnetic core, polydopamine (PDA) as a hydrophilic middle layer, and TbBd as an outer COF shell was facilely prepared as a novel hydrophilic platform for efficient detection of phthalic acid esters (PAEs). The resultant Fe3O4@PDA@TbBd nanosphere displayed strong magnetic response, high surface area, and good hydrophilicity. Accordingly, the newly synthesized COF exhibited great potential in phthalate analysis with a wide linearity (50–8000 ng/mL), good recovery (92.3–98.9%), a low limit of detection (0.0025–0.01 ng/mL), and a small relative standard deviation (for intraday less than 4.6% and for interday less than 6.8%). More excitingly, the new COF was applied to analyze nine PAEs in the human plasma sample. This work opens up new avenues for the development and application of functionalized COF-derived materials.
研究领域:
材料科学
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分析化学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
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2017
·Vol. 53
·期 3
·459-461
·
IF 0.603
Liu X. J.,Yan Y. N.,Wang S. Q.,Li X.,Liu X. G.
A new synthetic route to 4-methoxyisophthalic acid, the key intermediate in the synthesis of Picotamide, is reported. The new protocol starts from commercially available and cheap 4-methylphenol and includes four steps: esterification, Fries rearrangement, methylation, and oxidation; the overall yield is 49%. Unlike the traditional Blanc chloromethylation/oxidation scheme, the proposed procedure avoids using volatile and corrosive hydrochloric acid.
研究领域:
有机化学
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药物化学
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DOI
高影响因子
CATALYSIS TODAY
·
2015
·
IF 3.893
Jun Fu,Dezhang Ren,Lu Li,Yunjie Liu,Fangming Jin,Zhibao Huo
An efficient conversion of dimethyl phthalate (DMP) to phthalide (PHT) over CuO in aqueous media was investigated. Among the catalysts we tested, various metals or metal oxides were effective for the conversion of DMP to PHT in water, and CuO showed excellent catalytic activity and gave the best result. The PHT yield of 85% was achieved when Zn acted as a reductant. Mechanism study for the conversion of DMP suggested that an intermediate 2-hydroxymethyl benzoic acid was produced in the process. The present study provides a useful route for the production of PHT from DMP.
研究领域:
化学工程
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催化科学
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DOI
高影响因子
CHEMOSPHERE
·
2020
·
IF 5.778
Xiaotong Gu,Ning Qin,Guangfeng Wei,Yiqiong Hu,Ya-nan Zhang,Guohua Zhao
It is stubborn to remove the lowly concentrated phthalic acid esters (PAEs) that usually coexist with other highly concentrated but low-toxic pollutants in municipal sewage. Herein, we report a novel strategy for completely removing the PAEs over a bi-functional {001}TiO 2 surface (with highly exposed {001} facet), which not only serve as functional sites to specifically adsorb the target PAEs pollutants, but also contribute to an enhanced oxidation ability. The adsorption behavior of PAEs on {001}TiO 2 is analyzed deeply through kinetic experiments combining with in situ ATR-FTIR spectroscopy and theoretical calculations. The results reveal that the adsorption capacities of PAEs on {001}TiO 2 are about 4–5 times higher than that on TiO 2 , both of which follow the pseudo-second-order and Langmuir model. This is mainly attributed to the interfacial Lewis Acid-Base Pair between {001} facet Ti 5c sites and C O of PAEs. Benefitting from the specific adsorption capability toward target pollutant and enhanced oxidation ability of {001} facets, nearly 100% of DMP or DEP in simulated wastewater can be eliminated by {001}TiO 2 within 2 h illumination, and the relevant degradation rate constants ( k ) (3.67 h −1 for DMP and 2.19 h −1 for DEP) are 5.73 and 3.08 folds higher than that of pure TiO 2 , respectively. In the application of municipal wastewater , nearly 76% of DMP and 85% DEP can be eliminated by {001}TiO 2 within 2 h illumination, which are nearly 3–6 fold higher than that of pure TiO 2 .
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Journal of Food Measurement and Characterization
·
2023
·Vol. 17
·期 6
·6168-6179
·
IF 3.4
Xiang Gang,Li Wenzhuo,Nong Qiuxiang,Zhang Cuizhong,Zhang Zhengfa,Lian Huan,Peng Jinyun,Jiang Yufen,Tan Yiqiu,Sun Jing
Conjugated microporous polymers (CMPs) have been widely used in various fields as a new class of porous materials. In this study, a quinoxaline-based CMP (BQP-CMP) was prepared and used as the coating in SPME for the extraction and enrichment of nine phthalate esters (PAEs) in juice, soya sauce, cooking wine, and blended edible oil samples. Several parameters affecting solid-phase microextraction (SPME) were optimized. The feasibility of the developed method was verified using real samples, which showed low LODs (0.014–0.032 µg L −1 ), wide linearities (0.05–50 µg L −1 ), good repeatability (2.8–6.6%), and a long service life. The real liquid samples were successfully analyzed using this proposed method and spiked recoveries of 70.16–96.36% were obtained. Moreover, the interaction model and binding energies between BQP-CMP and the PAEs were explored using molecular docking. Satisfactory extraction efficiency was achieved owing to the high specific surface area (601.62 m 2 g −1 ), high hydrophobicity, and the conjugated planar structural unit distribution of BQP-CMP. This study demonstrates that BQP-CMP is excellent as a rapid and sensitive analysis material for PAEs at trace levels in various types of samples and that CMP materials are also excellent candidates for SPME coatings.
研究领域:
分析化学
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食品科学
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产品关联
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2025
·
IF 3.4
Zhonghua Li,Songgu Wu,Junbo Gong
The influence of halogen-atom substitution for a dimethyl isophthalate compound on the polymorphic behavior and isostructurality property was explored in this paper. Sublimation was demonstrated to exhibit remarkable advantages. Specifically, two polymorphs (Form I and Form II) of dimethyl 5-bromoisophthalate and two polymorphs (Form A and Form B) of dimethyl 5-iodoisophthalate were discovered for the first time. Moreover, the corresponding single crystals suitable for crystal structure determination were also successfully harvested within a few hours. More interestingly, the crystal packing similarities between the stable Form II and metastable Form A were established with the evaluation of quantitative analysis tools. The success in achieving the regulation of luminescence emission with the changes of crystal packing patterns, molecular conformations, and interactions via halogen substitution will provide some inspiration for the development of novel flexible optical solid-state systems in the future.
研究领域:
材料科学
·
晶体学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2020
·
IF 3.573
Yuan Liu,Jun Zhao,Yunyan Peng,Jun Luo,Lijun Cao,Xiaoqing Liu
Epoxy derived from heteroaromatic compounds and its properties are seldom reported. In this work, two model epoxy monomers (EP-B and EP-F) were synthesized from isophthalic acid and 2,5-furandicarboxylic acid. After curing with 4,4-diaminodiphenylmethane (DDM) in a stoichiometric quantity of 2:1, their properties were comparatively investigated, especially the formation and role of hydrogen bonding in them were identified. Results obtained from differential scanning calorimetry (DSC), dynamic thermomechanical analysis (DMA), fluorescence emission spectra, and static contact angle measurements showed that the cured EP-F/DDM system exhibited unexpected performance in higher glass transition temperature (Tg), fluorescence intensity, and hydrophilicity. And temperature-dependent Fourier transform infrared (FT-IR) analysis further confirmed that it was the more hydrogen bonding in the cured EP-F/DDM, involved with the oxygen heteroatoms in the furan ring, which led to its better properties. This work gives us some new insights into the role of electronegative heteroatoms in epoxy resin synthesized from heteroaromatic compounds.
研究领域:
材料科学
·
化学
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Ning Wang,Nan Zhang,Mei-Ling Sun,Yan Sun,Qing-Yu Dong,Yu Wang,Zeng-Tian Gu,Hai-Tao Ding,Qi-Long Qin,Yong Jiang,Xiu-Lan Chen,Yu-Zhong Zhang,Chao Gao,Chun-Yang Li
Phthalate esters (PAEs) are emerging hazardous and toxic chemicals that are extensively used as plasticizers or additives. Diethyl phthalate (DEP) and dimethyl phthalate (DMP), two kinds of PAEs, have been listed as the priority pollutants by many countries. PAE hydrolases are the most effective enzymes in PAE degradation, among which family IV esterases are predominate. However, only a few PAE hydrolases have been characterized, and as far as we know, no crystal structure of any PAE hydrolases of the family IV esterases is available to date. HylD1 is a PAE hydrolase of the family IV esterases, which can degrade DMP and DEP. Here, the recombinant HylD1 was characterized. HylD1 maintained a dimer in solution, and functioned under a relatively wide pH range. The crystal structures of HylD1 and its complex with monoethyl phthalate were solved. Residues involved in substrate binding were identified. The catalytic mechanism of HylD1 mediated by the catalytic triad Ser140-Asp231-His261 was further proposed. The hylD1 gene is widely distributed in different environments, suggesting its important role in PAEs degradation. This study provides a better understanding of PAEs hydrolysis , and lays out favorable bases for the rational design of highly-efficient PAEs degradation enzymes for industrial applications in future.
研究领域:
环境科学
·
生物化学
·
酶学
·
结构生物学
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产品关联
DOI
PubMed
高影响因子
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