ChemCatChem
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2020
·Vol. 12
·期 8
·2341-2347
·
IF 4.853
Bai-Chuan Zhou,Qing-Nan Wang,Xue-Fei Weng,Lei He,Wen-Cui Li,An-Hui Lu
Graphical Direct production of benzyl alcohol : The distribution of aromatic alcohols on cobalt-hydroxyapatite is greatly switched from methylbenzyl alcohol (feeding ethanol) to benzaldehyde (C 7 , BA=O) and benzyl alcohol (C 7 , BA−OH) by cofeeding of methanol and ethanol. Aromatic alcohols, often used for the synthesis of plasticizers, coatings and pharmaceuticals, are currently produced from the oxidation of petroleum-derived aromatic hydrocarbons. Herein, we report a non-petroleum and environmentally friendly route for the production of aromatic alcohols: cofeeding methanol with ethanol over cobalt-hydroxyapatite catalyst, in which the distribution of aromatic alcohols products can be regulated by varying methanol pressure. Co species on hydroxyapatite can activate both methanol and ethanol to yield their corresponding aldehydes (formaldehyde and acetaldehyde). The followed cross- and self-condensations of aldehydes are catalyzed by hydroxyapatite to produce acrolein and 2-butenal, which are the key intermediates for the formation of aromatic oxygenates. The sequential cross-condensation and dehydrocyclization of acrolein and 2-butenal yield benzaldehyde, which is then hydrogenated to benzyl alcohol. The direct production of benzyl alcohol from methanol and ethanol could be regarded as a cutting-edge example, which ensures a promising route for sustainable aromatic alcohols production.
研究领域:
化学工程
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催化科学
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环境科学
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DOI
高影响因子
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2022
·Vol. 101
·期 7
·4217-4229
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IF 2.5
Jia Wang,Rongchun Shen,Yueqiang Cao,Wei Li,Jinghong Zhou
1,2-butanediol (1,2-BDO) and 1,2-propanediol (1,2-PDO) are inevitably side produced in the ethylene glycol (EG) production processes from non-petroleum routes, but are very difficult to separate by the ordinary distillation method because of the closeness of their boiling temperatures to EG, thus compromise the economy of these processes. The azeotropic distillation process using 1-octanol (CPO) as an entrainer to separate EG and 1,2-BDO mixture with or without 1,2-PDO was studied in this paper. Four binary vapour–liquid equilibrium data of EG-1,2-BDO, EG-CPO, 1,2-BDO-CPO, and 1,2-PDO-CPO were measured using an Ellis equilibrium kettle and regressed with the thermodynamic model of non-random two liquid to obtain the corresponding binary interaction parameters. On this basis, azeotropic distillations with CPO as an entrainer were designed to separate EG and 1,2-BDO with or without 1,2-PDO. The complete separation processes, including the azeotropic distillation and CPO recovery process consisting of extraction with H 2 O and subsequent distillation, were simulated and optimized with Aspen Plus for both the EG-1,2-BDO binary mixture and the EG-1,2-BDO-1,2-PDO ternary mixture. The simulation results show that the azeotropic distillation method with CPO as an entrainer can effectively separate the mixture of EG-1,2-BDO and EG-1,2-BDO-1,2-PDO, achieving EG of 99.90% purity with 99.98% recovery and 1,2-BDO of 99.30% purity with 99.45% recovery for the binary mixture, and achieving EG of 99.90% purity with 99.80% recovery, 1,2-BDO of 99.35% purity with 99.35% recovery, and 1,2-PDO of 90.59% purity with 94.38% recovery for the ternary mixture. These processes are promising for industrial application and can significantly improve the economy of non-petroleum EG production.
研究领域:
化学工程
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分离技术
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DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2012
·
IF 2.422
Tianfei Zhang,Hengde Li,Weigang Zhang,Kazuhiro Tamura
(Liquid + liquid) equilibrium (LLE) data for {water (1) + methanol (2) + β-citronellol (3)} and {water (1) + ethanol (2) + β-citronellol (3)} ternary systems at T = (283.15, 298.15, and 313.15) K are reported. The immiscible region of (water + methanol + β-citronellol) system was found to be larger than that for the ethanol system at the same temperature. The effect of the temperature on the ternary (liquid + liquid) equilibria was examined and discussed. The experimental (liquid + liquid) equilibrium data have been satisfactorily represented by using extended UNIQUAC and modified UNIQUAC models.
研究领域:
化学工程
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物理化学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Xianglei Cao,Changyan Guo,Liugen Zhang,Meng Wang,Jia Guo,Yanfang Ma,Tingxiang Chen,Jide Wang
Photocatalytic alcohols decomposition is of great significance for the preparation of hydrogen and alcohol derivatives. Among which, the improvement of the hydrogen purity is very important for the later utilization. In this study, the photocatalytic gas-liquid products and formation rules/paths with C1-3 alcohols as substrates were summarized, and the reaction mechanisms were inferred based on the cycle experimental data and DFT calculation. For gaseous products, CH 4 , CO, C 2 H 4 or C 2 H 6 were also detected during the photocatalyzed alcohols decomposition in addition to hydrogen. The hydrogen yield from photocatalytic decomposition of isopropyl alcohol reached 65.98 mmol/g within 6 h, and it was proved to be the best substrate for hydrogen production due to the lowest CO content. For liquid products, the selectivity of acetal produced from ethanol can up to 99%. This work could facilitate the development of photocatalytic alcohol decomposition to produce higher purity hydrogen coupled with higher value-added liquid products.
研究领域:
化学
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材料科学
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能源科学
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产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Zixing Chen,Chi Ho Jacky Chau,Andrew Erickson,Huafang Ding,Shouhe Huang,Wen-Sen He,Hanyue Zhu,Zhen-Yu Chen
Phytosterols have long been used to prevent hypercholesterolemia-related diseases, although their effects on intestinal cholesterol metabolism remain elusive. This study applied comparative proteomics to investigate the effects of various sterols on proteomic changes in differentiated Caco-2 cells. A total of 206, 231, 180, and 197 differentially expressed proteins were identified following treatment with cholesterol, β-sitosterol, stigmasterol, and campesterol, respectively. Functional enrichment analysis revealed that phytosterols significantly altered the proteome of Caco-2 cells, though their effect on cholesterol transport protein expression was negligible. Notably, while phytosterols did not regulate the expression of acyl-CoA:cholesterol acyltransferase 2 (ACAT2), β-sitosterol and stigmasterol significantly lowered the level of cholesterol oleate in Caco-2 cells by 57.1 ± 0.8% and 51.4 ± 3.9%, respectively, demonstrating that they inhibited ACAT2-catalyzed cholesteryl esterification activity. In view of the fact that cholesterol needs to be converted to cholesteryl esters before incorporation into chylomicrons, it was concluded that phytosterols primarily reduce intestinal cholesterol absorption by inhibiting ACAT2 enzyme activity rather than its gene expression. This study provides new insights into the regulation of cholesterol homeostasis by phytosterols in the small intestine.
研究领域:
营养生物化学
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分子生物学
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细胞生物学
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脂质代谢
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药理学
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蛋白质组学
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产品关联
DOI
PubMed
高影响因子
POLYMER
·
2025
·
IF 4.5
Haoting Yin,Dongyuan Ye,Tianyu Wu,Xiaoyu Meng,Hai-Mu Ye
The sluggish crystallization kinetics of poly(ethylene succinate) (PES), a biodegradable aliphatic polyester with promising mechanical properties, severely restricts its industrial processing and application. To address this limitation, this study introduces two bio-derived hexahydric alcohols, myo -inositol (MIS) and dipentaerythritol (DPE), as nucleating agents to regulate PES crystallization. Non-isothermal and isothermal differential scanning calorimetry, polarized optical microscopy, and wide angle X-ray diffraction analyses reveal that both MIS and DPE significantly enhance nucleation density and crystallization rates via epitaxial templating and hydrogen-bonding interactions. DPE outperforms MIS, achieving 19.1 °C increase in crystallization temperature and 28% improvement in relative crystallinity at 2 wt% loading, attributed to its superior epitaxial surface provision and stronger intermolecular interactions for PES chains. Fourier transform infrared spectroscopy further confirms the plasticizing effect of these agents, which reduces rigid amorphous fractions and enhances chain mobility. The synergistic mechanism combines heterogeneous epitaxial nucleation and chain lubrication, enabling accelerated crystallization kinetics without compromising biodegradability. This work provides a sustainable strategy to optimize PES processing efficiency and performance, advancing its potential as a viable alternative to conventional thermoplastics.
研究领域:
材料科学
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生物化学
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产品关联
DOI
高影响因子
FLUID PHASE EQUILIBRIA
·
2013
·
IF 2.379
Xiang Liu,Yonghong Hu,Wenge Yang,Yan Liu,Mengmeng Liang
Data on corresponding solid–liquid equilibrium of erythritol in methanol, ethanol and methanol + ethanol was measured with temperature range from 283.15 K to 333.15 K under atmospheric pressure by employing the gravimetric method. The experimental results indicated that the solubility of erythritol in the solvents increases with increasing both temperature and mass fraction of organic solvents. The experimental data were well-correlated with the modified Apelblat equation, the λh equation and the van’t Hoff equation. In addition, the calculated solubilities showed good agreement with the experimental results. It was found that the modified Apelblat equation could obtain the better correlation results than the other two models. The standard enthalpy, standard entropy, and Gibbs free energy change of solution of erythritol were calculated from the solubility data by using the modified Apelblat model and the van’t Hoff equation. What's more, the experimental data and model parameters would be useful for optimizing the process of purification of erythritol in industry.
研究领域:
食品科学
·
化学工程
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产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2020
·
IF 3.573
Tiefeng Wang,Xu Li,Jinxiang Dong
Ethylene glycol (EG), synthesized from coal-based syngas, is frequently contaminated with refractory impurities 1,2-butanediol (BDO) and 1,2-propanediol (PDO), which affect the quality of EG for polyester production. Distillation, one of the existing methods employed, is still difficult for separation and purification due to the close boiling points. Melt crystallization is an effective technology to obtain high-purity organic compounds based on the difference in the melting points of each component in the mixture. Thus, in this work, we have explored the feasibility of the static melt crystallization on the separation of these two binary systems, EG/BDO and EG/PDO, respectively. For this purpose, a jacketed crystallization tube was adopted and the process was divided into three stages: seed generation, crystallization, and sweating. The crystallization parameters were investigated and fractal porous media theory was used to describe the state of the crude crystals. Furthermore, sweating was applied as a finishing treatment. The purity of ethylene glycol was recorded using gas chromatography, and its corresponding UV transmittance spectrum was studied. The results showed that the purity of ethylene glycol could reach ≥99.8% from the two binary systems studied and its UV transmittance at 220 nm was significantly improved by the tertiary separation process. Overall, melt crystallization has been proved as an effective way to solve the difficulty of separating these short-chain glycols.
研究领域:
化学工程
·
材料科学
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DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2017
·
IF 3.648
Junwei Zhang,Hang Li,Xiao Ma,Huanxin Li,Shuai Yang,Li Xu,Guoji Liu
The solubility of 1,6-Hexanediol in (ethyl acetate + methanol) and (ethyl acetate + n-butanol) binary solvents was determined by isothermal saturation method at atmospheric pressure of 101 kPa. The solubility of 1,6-Hexanediol in the two binary solvents increases with the increase of temperature at fixed mass fraction of ethyl acetate from 278.15 K to 298.15 K, and decreases with the increase of mass fraction of ethyl acetate at fixed temperature. In addition, experimental solubility data were correlated by modified Apelblat equations, Jouyban-Acree model and Sun model. Furthermore, the standard dissolution enthalpy was calculated.
研究领域:
物理化学
·
热力学
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2020
·
IF 2.888
Xingchuan Yang,Huanxin Li,Chunmei Cao,Li Xu,Guoji Liu
Liquid-liquid equilibria (LLE) data for ternary systems of water + 1,6-hexanediol + 1-pentanol/ 3-methyl-1-butanol/ 2-methyl-2-butanol were measured at (293.15, 303.15, 313.15 and 323.15) K under 101.3 kPa. Cloud-point method was applied to determine the solubility curves data. Distribution coefficient and separation factors for 1,6-hexanediol were calculated from the measured tie-line data to evaluate the extraction effect of alcohols on 1,6-hexanediol. The reliability of experimental LLE data were tested by Othmer–Tobias equation and Hand equation, NRTL and UNIQUAC models were applied to correlate the measured data and the calculated results show that both models can fit the experimental data very well.
研究领域:
化学工程
·
热力学
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DOI
高影响因子
FOOD CHEMISTRY
·
2020
·
IF 6.306
Hailong Sun,Shuangping Liu,Jieqi Mao,Ziwei Yu,Zhijie Lin,Jian Mao
Although huangjiu is a popular alcoholic beverage in China, the occurrence of quick-intoxication suppresses huangjiu consumption and impedes development of the huangjiu industry. In this study, the Cryprinus carpio intoxication model was used to compare the differences in intoxication effect of alcoholic beverages and to assess the impacts of huangjiu components on intoxication for the first time. Exposure to huangjiu led to the most rapid physical imbalance of C. carpio , followed by red wine and Western liquor. Higher alcohols, biogenic amines and aldehydes could cause physical imbalance of fish by themselves, and synergistic effects were observed when combined with ethanol. 2-Phenylethanoland and isopentanol had the greatest positive effect on huangjiu intoxication, followed by histamine and phenethylamine. No synergistic effect was observed between individual aldehydes and ethanol. Identification of these impactful huangjiu components provides a new perspective on the establishment of more rigorous control on the quality and flavor of huangjiu.
研究领域:
食品科学
·
饮料化学
·
水生毒理学
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Bingke Tian,Chaofeng Huang,Yingshuang Zhang,Cong li,Hongru Jiang,Chongqing Wang,Hui Wang,Shangbo Zhang,Liuchuang Zhao
Plastics are extensively used in packaging, automobiles, sanitation, agriculture, and architecture due to their lightweight, malleability, corrosion resistance, and low cost. However, their short lifespan leads to the rapid accumulation of plastic waste. Therefore, recycling waste plastics is crucial to conserve resources and protect the environment from "white pollution." This study developed a flotation process to facilitate the recycling of common polyesters by separating polyamide (PA), polycarbonate (PC), polyethylene terephthalate (PET), polymethyl methacrylate (PMMA), and polyurethane (PU). The flotation process was based on a hydrophilic gradient induced by modification with methanol, ethanol, and ethanolamine. The floatability sequence of the polyesters was PA < PU < PET < PC < < PMMA in the methanol-based system, PA < PU < PET < < PC ≈ PMMA in the ethanol-based system, and PET < PU < PA < < PC < PMMA in the ethanolamine-based system. The floatability of the polyesters was closely related to the reactivity of ester exchange. Based on the hydrophilic gradients, a cascaded flotation process was designed, following the ester exchange mechanism, to sequentially recover PET, PA, PC, and PMMA. PA, PET, and PU were the sinking plastics after modification with methanol, ethanol, and ethanolamine, respectively, while only PC remained hydrophilic after methanol modification. The purity of PA, PC, PET, and PMMA was 95.10 %, 93.68 %, 89.39 %, and 86.42 %, respectively, with recovery rates of 82.96 %, 83.90 %, 96.08 %, and 100 %. This study presents a promising approach for the flotation separation of waste polyesters.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）