Materials
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2017
·Vol. 10
·期 2
·191
·
IF 2.654
Yan Liu,Yuxuan Wu,Lei Zhou,Zhengao Wang,Cong Dai,Chengyun Ning,Guoxin Tan
Integration and stability of hydrogels and surrounding cartilage/bone tissue is crucial for both immediate functionality and long-term performance of the tissue. In this work, chondroitin sulphate (CS) a polysaccharide found in cartilage and other tissues was used to synthesize a tough hydrogel that was chemically functionalized with methacrylate and aldehyde groups, bonding to surrounding tissue via a dual-bonded approach. The hydrogel can not only chemically anchor onto implanted titanium at the subchondral bone, but also on cartilage tissue via the Schiff-base reaction. In vitro experiments confirmed that the strategy improved hydrogel implant stability with cartilage tissue, was favorable for chondrocyte attachment, and has the potential to quickly and effectively repair cartilage defects and maintain joint functionality for a long time.Keywords:titanium;chondroitin sulphate;cartilage tissue;aldehyde;adhesion
研究领域:
生物医学工程
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组织工程
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产品关联
DOI
PubMed
高影响因子
Desalination and Water Treatment
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2024
·
IF 1
Jingbo Ni,Ruyi Liu,Changhao Yan
The surface aldehyde assembled polystyrene microspheres (PS-CHO) were synthesized via the copolymerization of styrene and acrolein and characterized by Fourier-transform infrared spectroscopy and transmission electron microscopy. Some characteristic parameters, such as specific surface area, pore diameter distribution and zeta potential, were also determined. The content of aldehyde groups in the PS-CHO microspheres was inferred through potentiometric titration. Adsorption of uranium(VI) from an aqueous solution was investigated in a series of variable experiments. Effect of pH value, ionic strength, adsorbent dose, contact time and temperature on uranium(VI) adsorption were also discussed. Results showed that the optimum condition was the temperature of 313 K, 0.4 g L –1 of adsorbent dosage, pH value of 6.0 for 20 mg L –1 of uranium(VI) concentration. The maximum removal efficiency of uranium(VI) ions was 92.13%. Kinetic studies certified the pseudo-second-order was the best-suited model and the fitting linear plot of the intraparticle diffusion model did not pass the origin, indicating that chemical sorption was the rate-determining step of the adsorption mechanism rather than mass transfer. Also, the Elovich equation was consistent with the experimental data, meaning chemical interactions between microspheres and adsorbates. The adsorption capacity at the equilibrium of PS-CHO microspheres was estimated to be 46.07 mg g –1 at 313 K. Furthermore, about 96% of adsorbed uranium(VI) could be recovered by laconic perchloric acid treatment, suggesting the stability and reusability of PS-CHO microspheres.
研究领域:
环境科学
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材料科学
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化学工程
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DOI
高影响因子
DYES AND PIGMENTS
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2021
·
IF 4.889
Peng Wu,Yuan Xiong,Chen Lei,Yuan Li,Xiang Liu,Cheng Zhang,Yudie Sun,Jian Zhang,Chun-Sing Lee,Kui Zhang
Carbon dots or Carbon quantum dots (herein after abbreviated as CDs) with bight luminescence, derived from carbohydrates such as citric acid , glucose or sucrose, have been widely reported in recent publications. However, as to which functional groups and structures in CDs are responsible for luminescence, most explanations in current references are normally based on assumptions, instead of being convinced by the accurate information resting on experimental facts. Herein, we conducted an experimental study targeting at finding the fluorophores of CDs prepared from citric acid and glycine by fluorescent quenching. The experimental results revealed that the essence of fluorescence was manipulated by fluorophores of conjugated C C double bonds and aldehyde groups. The destruction of aldehyde groups or C C double bonds in the CDs led to a complete decay of luminescence. In addition, the results of this experiment were similar to those of CDs prepared from the sole citric acid, glucose or sucrose, which predicted the analogy of the CDs in chemical structures . Such information about fluorophore of CDs was valuable for further exploring more extensive application of CDs in sense technologies.
研究领域:
材料科学
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化学
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DOI
高影响因子
GREEN CHEMISTRY
·
2019
·Vol. 21
·期 21
·5828-5840
·
IF 9.405
Xinli Tong,Pengfei Guo,Shengyun Liao,Song Xue,Haigang Zhang
The selective transformation of the aldehyde group (–CHO) in multifunctional oxygenates is a key challenge in the development of sustainable biomass feedstock. Herein, a smart Ni-MFC catalyst was developed from a 2D Ni-based metal–organic framework (MOF), which efficiently promoted the transformation of –CHO in the presence of H2 to a methyl group (–CH3) via the reductive etherification and hydrogenolysis of the C–O ether bond in methanol. Moreover, the catalytic process could be controlled to directionally produce methyl ether (–CH2OR) using the reductive etherification protocol. For the catalytic reduction of vanillin, the Ni-MFC-700 catalyst guaranteed the full conversion of vanillin and 96.5% yield of the desired 2-methoxy-4-methylphenol (MMP), while the Ni-MFC-500 catalyst afforded about 82.7% yield of 4-(methoxymethyl)-2-methoxyphenol in methanol solvent. This is a novel and promising approach for the valorization of multifunctional oxygenates and biomass-derived platform compounds.
研究领域:
化学催化
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生物质转化
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有机合成
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DOI
高影响因子
Polymers
·
2022
·Vol. 14
·期 15
·3158
·
IF 4.967
Chunxia Zhu,Shuyu Pang,Zhaoxia Chen,Lehua Bi,Shuangfei Wang,Chen Liang,Chengrong Qin
At present, the synthesis methods of crystalline porous materials often involve powder products, which not only affects the practical application but also has complex synthesis operations and limited scale. Based on the mechanochemical method, we choose COF-TpPa-1, preparing TpPa-1-DANC composites. Covalent organic frameworks (COFs) are a kind of crystalline material formed by covalent bonds of light elements. COFs possess well pore structure and high thermal stability. However, the state of synthesized powders limits their application. Cellulose nanocrystals (CNCs) are promising renewable micron materials with abundant hydroxyl groups on their surface. It is possible to prepare high-strength materials such as film, water, and aerogel. Firstly, the nanocellulose was oxidized by the sodium periodate method to obtain aldehyde cellulose nanocrystals (DANC). TpPa-1-DANC not only had the crystal characteristic peak of COFs at 2θ ≈ 5° but also had a BET surface area of 247 m2/g. The chemical bonds between COFs and DANC formed by Schiff base reaction appeared in FTIR and XPS. The pyrolysis behavior of the composite was characterized by TG-IR, which showed that the composite had good thermal stability. With the advantages of nanocellulose as a material in every dimension, we believe that this method can be conducive to the large-scale synthesis of COFs composites, and has the possibility of multi-form synthesis of COFs.Keywords:covalent organic frameworks;aldehyde cellulose nanocrystals;mechanochemistry;TGA/FTIR
研究领域:
材料科学
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化学工程
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分析化学
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产品关联
DOI
PubMed
高影响因子
RSC Advances
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2020
·Vol. 10
·期 4
·1956-1965
·
IF 3.119
Weiqi Xie,Shiwen Huang,Donglin Tang,Shumei Liu,Jianqing Zhao
A furfural-based DOPO-containing flame retardant, 6,6′-(((methylenebis(4,1-phenylene))bis(azanediyl))bis(furan-2-ylmethylene))bis(dibenzo[c,e][1,2]oxaphosphinine 6-oxide) (MBF-DOPO), was synthesized and utilized as a co-curing agent of 4,4′-diaminodiphenyl methane (DDM) for fire-safe epoxy thermosets. For the cured epoxy resin containing 4.0% MBF-DOPO, the limiting oxygen index (LOI) reached 32.9% (with the V-0 rating in UL-94 test), and the peak heat release rate and total smoke production values were respectively decreased by 29.3% and 33.6%, compared to pure epoxy resin. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) results confirmed that the furfural-based flame retardant MBF-DOPO promoted the charring formation of the epoxy matrix, which effectively isolated the gas and heat transfer during combustion and thus enhanced the fire-safety performance of the epoxy thermosets. This work provides an effective route for synthesizing a furfural-based flame retardant, which possesses great potential for application in fire-safe epoxy thermosets.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
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2024
·
IF 5.6
Jiayi Lv,Chenglong Zou,Qi Dai,Yin Zhao,Mengqi Zhu,Xiyue Liu,Siqi Huan,Shuo Dou,Long Bai
Pickering emulsions stabilized by nanocelluloses have been utilized within food, cosmetic, and pharmaceutical industries owing to their prolonged stability. However, high hydrophilicity and large dimension of cellulose nanofibrils (CNF) obtained through mechanical disintegration limit their adsorption at the oil/water interface. Herein, aldehyde-modified TEMPO-oxidized CNF (ACNF) with different oxidation degrees is prepared to improve Pickering emulsion stability, broadening its application in asphalt recovery. A battery of characterization methods (TEM, turbidity, contact angle, etc.) demonstrate the installation of aldehyde groups on the ACNF and change of the properties. The aldehyde groups improve hydrophobicity of ACNF while maintaining sufficient carboxyl groups to retain electrostatic repulsion. The fiber length of ACNF decreases with increasing aldylation degree, influencing the amount of ACNF absorbed at the droplet surface. Pickering emulsion stabilized by ACNF-0.12 show optimal performances. The obtained ACNF effectively stabilizes high oil content and different oil types with long-term stability. Flowable Pickering emulsions containing asphalt are obtained. This study offers comprehensive investigation on the influence of aldehyde-modified ACNF on Pickering emulsion preparation, aiming at developing new approaches for various applications.
研究领域:
材料科学
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化学工程
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环境科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2020
·
IF 5.162
Chunyu Liu,Chenyu Liu,Simiao Yu,Ning Wang,Weihe Yao,Xia Liu,Guozhen Sun,Qiling Song,Weihong Qiao
Montmorillonite (MMT) powder, as the most effective hemostats in natural silicates, is restricted for commercial application due to its embolic effect. Until now, it's still a challenge to control the leakage of MMT and avoid its side-effects. Herein, poly aldehyde dextran (PDA)/MMT composite sponge (PM) with commendable tissue adhesion, antibacterial, and wound healing performances is developed for massive hemorrhage control. Based on the high degree of perfect synergism of PDA and MMT, the PM sponge can rapidly seal the wound, and promote cells aggregation and adhesion, whole coagulation system activation, resulting in shortened clotting time from 480 s to <10 s in vitro. Therefore, PM sponge with low exothermic effects achieves hemostasis in limited time, decreasing nearly 95% blood loss in the femoral artery and vein incision in rat models. Furthermore, with the intensive tissue adhesion (~47 kPa), PM sponge not only exhibits antibacterial activity to Escherichia coli , but also succeeds in accelerating wound healing. Importantly, the low cytotoxic sponge verifies to be a little hemolytic and skin irritant hemostat. Thus, the biocompatible PM sponge may provide a new strategy for reintroduction of MMT in hemostatic fields, and a safe-effective avenue for clays to control bleeding.
研究领域:
生物材料学
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医学工程
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创伤修复
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产品关联
DOI
PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
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2020
·
IF 3.862
Xunzheng Su,Zhen Zhou,Jingcheng Liu,Jing Luo,Ren Liu
In this paper, a high-performance epoxy resin was synthesized from vanillin , and the polyimine-epoxy cross-linked network was prepared via in-situ formation of the Schiff base structure. The chemical structures, thermal and mechanical properties of vanillin-based epoxy resin (DADE) and diglycidyl ether of bisphenol A epoxy resin (DGEBA) were characterized by fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance spectra ( 1 H NMR), differential scanning calorimetry (DSC), and dynamic thermomechanical analysis (DMA). The results indicated that the DADE showed better thermal and mechanical properties than DGEBA after cured by the same primary amine (D230). The prepared DADE-D230 showed higher Tg (106℃), tensile strength (57.4 MPa) and elongation at break (3.1%) than DGEBA-D230 (98℃, 45.1 MPa, and 2.4%, respectively). Moreover, it can be recycled at a hot pressing, and the reprocessed samples showed a comparable performance with DGEBA.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Kangming Xiong,Fangjun Huo,Yongbin Zhang,Ying Wen,Jianbin Chao,Caixia Yin
In this study, we have developed two fluorescent probes for hypochlorite based on a novel recognition mechanism: aldehyde group oxidized into carboxyl group by sodium hypochlorite. The new mechanism was proved by 1 H NMR, 13 C NMR and ESI–MS analysis for their reacting products. UV–vis and fluorescence titration spectra for ClO − were investigated in PBS (pH 7.4). The detection limits of probe 1 and probe 2 were found to be as low as 77.82 nM and 61.14 nM, respectively. Furthermore, the probes could be used to monitor intracellular ClO − in RAW264.7 macrophage cells.
研究领域:
生物化学
·
分析化学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
De-qiang Li,Maryamgul Tohti,Yong-sheng Fu,Yue Zhang,Zi-wei Xiong,Jun Li,Yan-Feng Guo
Periodate oxidation has been the widely accepted route for obtaining aldehyde group-functionalized polysaccharides but significantly influenced the various physicochemical properties due to the ring opening of the backbone of polysaccharides. The present study, for the first time, presents a novel method for the preparation of aldehyde group-functionalized polysaccharides that could retain the ring structure and the consequent rigidity of the backbone. Pectin was collected as the representative of polysaccharides and modified with cyclopropyl formaldehyde to obtain pectin aldehyde (AP), which was further crosslinked by DL-lysine (LYS) via the Schiff base reaction to prepare injectable hydrogel. The feasibility of the functionalization was proved by FT-IR and 1 H NMR techniques. The obtained hydrogel showed acceptable mechanical properties, self-healing ability, syringeability, and sustained-release performance. Also, as-prepared injectable hydrogel presented great biocompatibility with a cell proliferation rate of 96 %, and the drug-loaded hydrogel exhibited clear inhibition of cancer cell proliferation. Overall, the present study showed a new method for the preparation of aldehyde group-functionalized polysaccharides, and the drug-loaded hydrogel has potential in drug release applications.
研究领域:
生物材料学
·
药剂学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF POLYMER SCIENCE
·
2021
·Vol. 59
·期 13
·1390-1398
·
IF 0
Yaochen Zheng,Peng Song,Shaoxiang Liu,Mengqing Wu,Hui Xu,Chenghui Qiao,Jian Liu,Zhengguo Gao,Qingfu Ban
Spiroacetal moieties containing linear telechelic polymers (LTPs) with two terminal epoxy groups were facilely synthesized via the successive thiol-ene and thiol-epoxy click additions. The LTPs were incorporated into epoxy matrix to fabricate the transparent and toughening thermosets. In term of the miscibility of epoxy with the adduct of ethanedithiol and 3,9-divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane (BTU), it is proposed that the size of the formed nanostructures was small enough to allow light penetrate. Therefore, the modified thermosets were transparent, which was further confirmed by small-angle X-ray scattering (SAXS) measurements. The LTPs with an alternating structure of rigid spiroacetal moiety and soft thioether could formed heterogeneous crosslinked networks (HCNs) and obviously toughen epoxy thermosets. Flexural strength increased from 1.06 GPa for neat epoxy to 2.09 GPa for toughening thermosets modified with 15 wt% LTPs. The stress field intensity ( K IC ) value reached up to 3.93 by more than 125% compared with that of the control sample (1.75). This work uncovered the role of HCNs on performance and paved a way for technological advances toward transparent and toughening materials in epoxy thermosets. Graphical
研究领域:
材料科学
·
高分子化学
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产品关联
DOI
危险品化学品经营许可证（带存储）