SENSORS AND ACTUATORS B-CHEMICAL
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2019
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IF 6.393
Zhen Li,Mei Li,Cong Wang,Xinhui Zhou,Jianfeng Li,Daoliang Li
Based on modified diazo reaction, a novel surface-enhanced resonance Raman scattering (SERRS) method employed for ultrasensitive, highly selective, and ultra-trace determination of nitrite in aquaculture water was demonstrated. The azo dyes, which are formed by 4-aminothiophenol, nitrite, and N-(1-naphthyl) ethylenediamine dihydrochloride in acid conditions, can exhibit high SERS signal on Ag nanoparticles. Subsequently, the concentration of nitrite can be determined from the intensity of SERRS of derivative. Under optimal conditions, a linear relationship between Raman intensity and the nitrite concentration was found in the range of 0.1–15.0 μmol L −1 with a good correlation coefficient (R 2 = 0.9921) at 1380 cm −1 , and the limit of detection can reach as low as 16.4, 24.0, 9.0, and 24.6 nmol L −1 at 1138, 1332, 1380 and 1418 cm −1 , respectively. Additionally, the results indicate that the present method can be applied to detect nitrite in real aquaculture water samples without influence of interfering ions. This study provides a feasible method for accurate, trace, and fast field detection of nitrite in aquaculture water with strong potential to be used for on-line and on-site optical sensors of nitrites.
研究领域:
环境科学
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分析化学
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产品关联
DOI
高影响因子
RSC Advances
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2015
·Vol. 5
·期 55
·44492-44498
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IF 3.84
Yuwei Wang,Linghui Meng,Liquan Fan,Guangshun Wu,Lichun Ma,Yudong Huang
Raw carbon nanotube (CNT)/carbon fiber (CF) hybrids were achieved through a two-step aryl diazonium reaction in mild, eco-friendly conditions. Raman spectra, Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) confirmed the grafting of CNT onto the CF surface. The surface topography and surface free energy of the modified CFs were examined by scanning electron microscopy (SEM), transmission electron microscope (TEM) and dynamic contact angle (DCA) tests, respectively. The resulting CNT/CF hybrid formed a strong chemical bond between the fiber and matrix and enhanced the surface wettability of the modified CFs. The interfacial shear strength (IFSS) of the CNT/CF hybrid reinforced composites increased by 104% compared with that of the untreated CFs. Moreover, the mechanical properties of the CNT/CF hybrid showed a slight improvement after modification.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
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2014
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IF 2.538
Yuwei Wang,Linghui Meng,Liquan Fan,Lichun Ma,Meiwei Qi,Jiali Yu,Yudong Huang
Polyacrylonitrile-based carbon fibers were functionalized with phenyl amine group via aryl diazonium reaction “on water” to improve their interfacial bonding with resin matrix. Raman spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy were employed to characterize ordered degree, functional groups, chemical states and morphology of carbon fiber surface, respectively. The results showed that phenyl amine groups were grafted on the fiber surface successfully. Mechanical property test results indicated that the aryl diazonium reaction in this paper could improve the interfacial shear strength by 73%, while the tensile strength was down very slightly. Hence aryl diazonium reaction “on water” could be a facile green platform to functionalize carbon fibers for many interesting applications.
研究领域:
材料科学
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表面化学
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产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2020
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IF 5.977
Min Fan,Dechan Lu,Ruiyun You,Cairou Chen,Yudong Lu,Yang Wu,Huiying Shen,Shangyuan Feng
Tryptophan plays an important role in the metabolic pathway and tryptophan metabolism is abnormal in tumor tissues. Therefore, Trp and its metabolites in body fluids can be used as tumor markers for cancer monitoring. However, the traditional tryptophan detection method has many shortcomings, such as low sensitivity, time-consuming and so on, which is difficult to meet the clinical needs. Herein, a rapidly, sensitive and reliable method for indirectly detecting Tryptophan (Trp) in serum was proposed by combining diazo-coupling reaction mechanism with surface-enhanced Raman scattering (SERS). The limit of detection (LOD) of Trp can be as low as 20 nM, which is much lower than existing detection methods. In addition, because of obvious change in color in diazo-coupling reaction, a colorimetric detection was applied for convenient determination of Trp in the concentration ranged from 3 × 10 −5 - 10 −3 M. Furthermore, with the support of good results by SERS assay, the presented method was successfully carried out for the determination of Trp in serum that came from healthy people and colorectal cancer patients. Comparing the difference of Trp content in serum between the two groups, it was found that tryptophan metabolism disorder exists in colorectal cancer patients, which suggested that the accurate detection of tryptophan content may provide important reference for the pathogenesis, prediction and prevention of colorectal cancer.
研究领域:
分析化学
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癌症研究
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生物化学
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临床诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
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IF 8.5
Rui Tan,Mei Zeng,Qiuwen Huang,Na Zhou,Mengjiang Deng,Yuanyuan Li,Xiaojun Luo
The presence of nitrite in food products has generated significant public concern. A simple and rapid dual-mode surface-enhanced Raman spectroscopy (SERS)/colorimetric detection of nitrite is proposed based on a diazo reaction and multifunctional gold nanoparticle-doped covalent organic framework (Au@COF) composite. Under acidic conditions, the reaction between toluidine blue and nitrite yielded a colorless diazo salt, simultaneously attenuating its characteristic absorption peak and Raman signal. The multifunctional Au@COF materials enhanced the Raman signal and ensured good reproducibility. Additionally, the reaction rates improved, and the sensitivity was enhanced due to the excellent adsorption capacity of the COF. The proposed method demonstrated high sensitivity and excellent recovery rates for nitrite detection in food samples. This approach shows potential for precisely detecting nitrite content in real-world food samples by integrating the simplicity of colorimetric analysis with the enhanced sensitivity of SERS.
研究领域:
分析化学
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食品科学
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纳米技术
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光谱学
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2020
·Vol. 412
·期 4
·993-1002
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IF 3.637
Li Wenshuai,Huang Saipeng,Wen Huiyun,Luo Yane,Cheng Jiewei,Jia Zhao,Han Pu,Xue Weiming
The nitrite ion (NO 2 − ) is a vital inorganic species that occurs both in natural ecological systems and human bodies. The high concentration of NO 2 − can be harmful for animal and human health. It is important to develop a simple, sensitive, reliable, and economic methodology to precisely monitor NO 2 − in various environmental and biological fields. Thus, a novel nitrite biosensor based on carbon quantum dots (PA-CDs) has been constructed and prepared via a high-efficiency, one-pot hydrothermal route using primary arylamines (PA) such as m -phenylenediamine. The device exhibits bright green fluorescence and a high quantum yield of 20.1% in water. In addition, the PA-CDs also possess two broad linear ranges: 0.05–1.0 μM and 1.0–50 μM with a low detection limit of 7.1 nM. The classical diazo reaction is firstly integrated into the PA-CD system by primary arylamines, which endows the system with high sensitivity and specific selectivity towards nitrite. Importantly, the nanosensor can detect NO 2 − in environmental water and serum samples with high fluorescence recoveries, demonstrating its feasibility in practical applications. This work broadens a new method to fabricate novel nanosensors and provides a prospective application for fluorescent carbon quantum dots (CDs).
Graphical abstract
研究领域:
分析化学
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环境科学
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纳米技术
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生物化学
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产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
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2019
·
IF 9.518
Xiang Pan,Linhu Li,Hangduo Lin,Jiayi Tan,Haitao Wang,Mengling Liao,Caiju Chen,Beibei Shan,Yingfan Chen,Ming Li
We report a paper-based surface-enhanced Raman spectroscopy (SERS) biosensor integrating the enrichment capability, namely enPSERS biosensor, for the sensitive, label-free detection of free bilirubin in blood serum for the accurate diagnosis of jaundice and its related diseases. This biosensor comprises multifunctional graphene oxide-plasmonic gold nanostar (GO-GNS) hybrids decorated on the filter paper, which integrates the high sensitivity of SERS detection, enrichment for serum bilirubin and fluorescence superquenching capability of GO-GNS hybrids for sensitive detection of serum bilirubin. The study of adsorption kinetics reveals that both electrostatic and π-π interactions between the GO-GNS hybrids and targets are responsible for the enrichment of bilirubin, and the adsorption process follows the pseudo-second-order kinetic model . The results of SERS detection of bilirubin in blood serum show two differential linear response ranges from 5.0 to 150 μM and 150–500 μM with the detection limit as low as 0.436 μM. The comparison of the results obtained from our present enPSERS biosensor with the commercial diazo reaction method for determination of free bilirubin in blood serum reveals the clinical effectiveness and suitability of the developed paper-based SERS biosensor. We believe that this sensitive and label-free SERS biosensor holds considerable promise for clinical translation in accurate diagnosis of jaundice.
研究领域:
纳米技术
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生物传感
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分析化学
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医学诊断
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）