TALANTA
·
2020
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IF 5.339
Rui Gao,Dan Li,Siqing Zheng,Haixin Gu,Wei Deng
Accurate and selective in-field detection of metal ions in complex media has gained wide interests due to the complexed matrices and weak affinity towards sensing surface. Herein, we develop a first trimodal method for sensing of Zn 2+ in complex matrices by stimuli-responsive N-[6-piperazinyl-2-pyridinyl]-N-(2-pyridinylmethyl)-2-Pyridinemethanamine dithiocarbamates (DPY) modified gold nanorods (GNRs-DPY). The presence of Zn 2+ triggers the aggregation of GNRs-DPY, leading to increment of color and fluorescence intensity of the sensing system, which could be visually discerned with bare eye. Moreover, the intensive electromagnetic enhancement among “hot spots” of GNRs, generated during self-aggregation of the GNRs-DPY caused by Zn 2+ , lowers the detection limit of SERS assay to 6 × 10 −3 pM. It is noteworthy that GNRs-DPY based sensing platform not only enables distinguishing Zn 2+ from Cd 2+ , with simplicity and rapidity, but also demonstrates as trimodal nanoprobe for sensitive and selective quantitative determination of Zn 2+ in different matrices. Therefore, the GNRs-DPY provides a new strategy for accurate and credible on-spot determination of Zn 2+ in complicated specimens, as well as offering multiple applications in point-of-care monitoring.
研究领域:
分析化学
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纳米生物技术
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环境监测
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分子诊断
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金属离子传感
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高影响因子
MATERIALS RESEARCH BULLETIN
·
2019
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IF 3.355
Yanqiu Zhang,Sai Xu,Xiangping Li,Jinsu Zhang,Jiashi Sun,Haiping Xia,Ruinian Hua,Baojiu Chen
Novel nanoplatform with excellent photothermal conversion and temperature feedback are preferable in clinical photothermal therapy (PTT). In this work, a hybrid of NaYF 4 :Er 3+ ,Yb 3+ @NaYF 4 upconversion nanoparticles (UCNPs) conjugated with gold nanorods (GNRs) was fabricated in order to achieve effective photothermal conversion and excellent temperature detection. In this nanoplatform, the GNRs as photo-activated nano-heaters could effectively convert the 808 nm photoenergy into heat, meanwhile UCNPs as 980 nm triggered temperature probe could read the temperature in an exact microdomain where the nanocomposite was located at. The effects of excitation source, GNRs concentration and power density on photothermal conversion were investigated. In addition, the difference between eigen temperature of nanoparticles and solution temperature, and the potential for temperature feedback were analyzed under double lasers excitation. Moreover, the photothermal conversion efficiency was experimentally confirmed from thermodynamic analysis. It was found that the nanocomposite can be an excellent nanoplatform for potential application in advanced PTT.
研究领域:
生物医学工程
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纳米医学
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肿瘤治疗
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光热疗法
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分子影像
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热疗监测
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转化医学
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
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IF 8.3
Yunli Peng,Guoquan Wang,Guifeng Li,Yuan Gong,Xi Yang,Xiaotian Tan,Tao Zhu,Chaoyang Gong
Apoptosis detection is significant for understanding fundamental biological processes and is closely associated with numerous diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. However, limited by the intrinsic complexity of physiological environments, achieving highly sensitive detection of apoptotic signals at the single-molecule level remains a major challenge. Here, we propose a label-free single-molecule apoptosis assay based on fiber-optic interferometric imaging. The interference pattern generated by scattered light on the microfiber surface was utilized to resolve localized phase changes, enabling single-particle and single-molecule sensitivity. We found that the dynamic evolution of the interference patterns correlates with the physical heterogeneity among different molecular species, including the surface charge and molecular weight of individual molecules. We achieved single-molecule detection of small proteins down to 5.8 kDa, demonstrating the broad applicability of our method across a wide range of clinically relevant proteins and nucleic acids. After functionalizing the fiber surface with antibodies, the interference patterns exhibited excellent specificity toward the antigen molecules. The dynamic interference pattern was further employed to perform an apoptosis assay at the single-molecule level. Our method enables label-free quantification of biomarkers in complex physiological environments with ultrahigh sensitivity, opening new avenues for fundamental studies of cell-death pathways and early disease diagnosis.
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npj Flexible Electronics
·
2026
·
IF 15.4
Kan Xinyuan,Fan Qian,Guo Wenlan,Sun Chen,Wang Yan,Duan Xuexin,Xue Qiannan
Ocular blood oxygen saturation is critical for detecting vision-threatening and systemic diseases. Existing wearable oxygen sensors are unsuitable for ocular use, and current ocular SpO₂ measurements rely on bulky equipment. This work introduces a flexible plasmonic nano-confinement (PNC) nanowire photodetector, based on a PNC nanowire array consisting of highly aligned and ordered PEDOT:PSS nanowires with embedded gold nanoparticles, for high-sensitivity oxygen saturation sensing. The PNC nanowire array acts as an anode interfacial modification layer, where nanowire-geometry-induced confinement and localized surface plasmon resonance synergistically lower the hole-extraction barrier, suppress interfacial recombination, and enhance photoconversion efficiency. Its flexible and transparent design, combined with a compact backend circuit using wavelet-threshold denoising, enables integration into a smart contact lens for accurate and stable non-invasive ocular oxygen monitoring. In vivo experiments demonstrate that this smart contact lens could provide a simple, non-invasive platform for continuous ocular SpO₂ monitoring, with potential relevance to systemic oxygen-status assessment.
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Cell Communication and Signaling
·
2026
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IF 11.6
Diao Jiayong,He Qixuan,Liu Quanzhen,Liu Yuxuan,Chen Simiao,Zhang Yuzhe,Gui Houda,Chen Jingyi,wu Dongni,Pang Xinyu,Zhang Qingyue,Wang Ya-nan,Zhang Dongjiao
Background Mitochondria, as crucial organelles in eukaryotic cells, are deeply involved in cellular energy metabolism and biogenesis. Currently, mitochondria have been found to transfer between cells and regulate a range of cellular functions and research has found that mitochondrial transfer has been shown to play an important role in regulating bone homeostasis. Methods Laser confocal imaging was used to confirm the occurrence of mitochondrial transfer between cells. JC-1 staining explains the state of free mitochondria in receptor cells. In order to reveal the relationship between the state and function of free mitochondria, osteogenic induction, Western blotting, flow cytometry, and in vivo experiments were conducted. RNA seq is used to analyze changes in cells. Different inhibitors were used to verify the specific mechanism of action of free mitochondrial transfer. Results Free mitochondrial transfer can improve the function of receptor cells through lysosomal pathway. Free mitochondria are degraded by cathepsin H (Ctsh) in lysosomes and release a large amount of cysteine after entering the receptor cells. In this process, the existence of membrane potential of free mitochondria is not critical. Cysteine, as the most important raw material for glutathione synthesis, can enhance the number and function of mitochondria in receptor cells. Conclusion Our study demonstrates that free mitochondrial transfer promotes bone regeneration by increasing cysteine supply, and provides innovative insights for understanding mitochondrial transfer.
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PubMed
高影响因子
ChemCatChem
·
2026
·Vol. 18
·期 16
·e71036
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IF 4.1
Xiang Gao,Longfei Hong,Yuting Jiang,Yixuan Li,Lian-Hua Xu,Qingyu Liu,Huiyan Zhang,Sheng Chu
Polyolefin plastics, such as polyethylene (PE), possess chemically inert and nonpolar C–C backbones, making them difficult to recycle and causing persistent environmental pollution. The lack of green and highly selective upcycling methods has led to severe environmental concerns and resource waste. Photoelectrocatalysis utilizes high-energy photogenerated charge carriers to directionally upgrade plastic-derived small molecules into value-added chemicals. However, current photoelectrocatalytic technologies still face challenges in processing structurally inert bulk polymer plastics. In this study, we report a hydrothermal-photoelectrocatalytic tandem strategy to realize the upcycling of PE and other polyolefin plastics. The acetic acid product obtained from hydrothermal treatment are further converted into ethanol over an Au nanoparticle‑decorated GaN/Si (Au/GaN/Si) photocathode, achieving an optimal performance of a Faradaic efficiency of 57.6%. This tandem strategy also demonstrates excellent generality in the conversion of polypropylene (PP) and polyvinyl chloride (PVC), providing a green route for the upcycling of polyolefin plastics. Graphical Hydrothermal-photoelectrocatalytic tandem upcycling enables the conversion of chemically inert polyolefin plastics into value-added ethanol. The Au/GaN/Si photocathode achieves a Faradaic efficiency of 57.6% for ethanol production, while demonstrating broad applicability to PE, PP, and PVC plastics.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Shuhan Hou,Inseob Noh,Xinlu Shi,Yanbin Wang,Hyung Do Kim,Hideo Ohkita,Biaobing Wang
Flexible superhydrophobic surfaces have been attracting more and more attention due to their foldable property. However, the superhydrophobic structure was easily damaged or destroyed owing to their poor interfacial force between substrate and superhydrophobic coating. Herein, fluorinated silica nanoparticles (F-SiO 2 ) were sprayed onto the wet poly(amide–imide) (PAI) surface, which made F-SiO 2 easily went into PAI substrate to enhance the durability of superhydrophobic surface. The PAI/F-SiO 2 flexible surface exhibited a water contact angle (CA) of beyond 160° and a sliding angle (SA) of as low as 3°, while the tensile strength (34 MPa) was comparable to that of PAI substrate (35.8 MPa). Encouragingly, the superhydrophobicity and hierarchical porous structure of PAI/F-SiO 2 surface were maintained even they were folded by 5000 times or underwent sandpaper abrasion test (500 cm of wear on a 1200 grit sandpaper under 50 g load), while the nanocomposites failed the sandpaper abrasion test when F-SiO 2 were sprayed onto completely dried PAI surface. More importantly, the CA and SA just slightly decreased when PAI/F-SiO 2 surfaces were heated at 300 °C for 24 h due to the unique surface morphology and high thermal stability of PAI, which is one of the highest thermal stabilities for flexible superhydrophobic films. In addition, PAI/F-SiO 2 surfaces maintained superhydrophobic after hot water jet impact, acid–base immersing, UV irradiation , and ultrasonic treatment , indicating the fabricated surfaces could be used for practical application especially under harsh conditions. Furthermore, the superhydrophobic surfaces possessed icephobic properties. It should be noted that PAI/F-SiO 2 surfaces showed such excellent properties, although their fabricating procedure did not undergo any optimization. This wet spraying method was also used to fabricate flexible superhydrophobic surfaces with other polymers as substrates such as poly(acrylic acid) (PAA), thermoplastic polyurethane (TPU), polystyrene (PS), and poly(vinyl alcohol) (PVA). Therefore, the simple strategy provided a general route to prepare flexible superhydrophobic films with high durability.
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ACS Omega
·
2023
·
IF 4.1
Bolin Wang,Yuxue Yue,Yuliang Li,Lu Yu,Hong Tang,Haifeng Zhang,Feng Feng
Imidazolium-based ionic liquid mixtures with [NO3]− and [AlCl4]− anions were used as oxidizing agents for the dissolution of Au, Pd, and Pt metals under mild conditions. The thermodynamic reduction of [NO3]− to [NO] is catalyzed by [AlCl4]− anions and coupled with the oxidation process of noble metals. The developed ionic liquid system for dissolving Au can reactivate the Au0 formed in the deactivation process of the catalyst in vinyl chloride production. This demonstrates the relevance of the here-presented work for technical noble metal recycling.
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PubMed
高影响因子
ORGANIC ELECTRONICS
·
2023
·
IF 3.2
Jinyao Zhong,Haitao Xu,Junwei Zhao,Fuhao Gao,Jinxin Zhou,Yongbing Long
Microcavity-based semitransparent organic solar cells (ST-OSCs) have become a hot issue in the research field of green energy harvesting due to their wider potential applications in colored photovoltaic glass, building-integrated photovoltaics, and so on. However, for this kind of ST-OSCs, high photoelectric conversion efficiency (PCE) and high peak transmittance cannot usually be achieved simultaneously. To circumvent the problem, this paper proposes MgF 2 microcavity with a structure of Au/Ag/MgF 2 /Ag for ST-OSCs so that high peak transmittance can be achieved at low cost of PCE. The device structure of ST-OSCs is Glass/ITO/ZnO/PTB7-Th: IEICO-4F/MoO 3 /Au/Ag/MgF 2 /Ag. By combining the high transmittance of MgF 2 microcavities with the low absorption of IEICO-4F in the blue light, a colorful ST-OSCs with high blue light transmittance can be obtained. The IEICO-4F in the active layer shows strong optical absorption in the near-infrared wavelength region, but weak absorption in the visible region. The results demonstrate that the peak transmittance of ST-OSCs reached a high value of 48% at 440 nm and the PCE reached 10.4%. Such a high peak transmittance is achieved while the PCE reduction compared to the control opaque device is about 5%. The PCE loss rate at each peak transmittance is the lowest among the reported values for the similar ST-OSCs devices. By adjusting the thickness of MgF 2 , ST-OSCs with different colors can be obtained, the peak transmittance of which is over 32% and the PCE loss rate is less than 7.25%. This report provides a new approach to solve the trade-off between efficiency and transmittance of ST-OSCs.
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JOURNAL OF MOLECULAR LIQUIDS
·
2022
·
IF 6.633
Pengcheng Li,Shujuan Dai,Xiaoan Li,Wenhan Sun,Shujie Liu
The leaching rates for gold in the roasting oxidation pretreatment-cyanidation gold leaching process are generally low. An adsorption experiment for quartz baking slag (roasting time of 3 h, roasting temperature of 650℃) and gold cyanide solution was carried out under different stirring time conditions. It is found that after high temperature activation of the quartz surface, gold cyanide can be adsorbed. When the stirring time reaches 50 min, the adsorption rate is 6.08%, and the unit adsorption amount is 0.05 mg·g −1 . The EDS spectrum clearly shows that the Au element is distributed among Si and O, and 0.02% Au is adsorbed on the surface of the quartz baking slag. To further prove the adsorption mechanism for the gold cyanide solution and quartz slag, infrared spectroscopy (IR) and X-ray photoelectron spectroscopy (XPS) were used to characterize the surface of quartz slags. Infrared spectroscopy analysis shows that new peaks emerge at 1429 cm −1 , 1878 cm −1 , and 1996 cm −1 after the elution experiment, and the characteristic peaks for inorganic cyanide are observed at 1878 cm −1 and 1996 cm −1 . This shows that after high-temperature activation of the quartz baking slag, chemical adsorption of gold cyanide occurs. The results obtained from X-ray photoelectron spectroscopy (XPS) show that during the adsorption process, Au-Si is adsorbed together, and Au shows a valence of + 1, which indicates that Au(CN) 2− ions are adsorbed onto the quartz activated at high temperature. Density functional theory (DFT) was used to determine the adsorption mechanism for Au(CN) 2− ions and different sites on the surface of quartz (1 0 1) before and after high-temperature activation (three Au-O, Au-Si, and N-Si adsorption sites). During the high-temperature activation process, the Au-O bonds and interactions on the surface of gold cyanide and quartz gradually transform into Au-Si bonds and interactions, and the N-Si bonds are also enhanced. This shows that the adsorption of gold cyanide onto quartz baking slag is enhanced after high-temperature activation. The simulation calculation result is consistent with the experimental results.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Rui Zhou,Dong-Jie Cui,Qi Zhao,Kai-Kai Liu,Wen-Bo Zhao,Qian Liu,Ruo-Nan Ma,Zhen Jiao,Lin Dong,Chong-Xin Shan
The microbial spoilage of soybeans during soaking process severely deteriorates the quality of soybean products and threatens human health. Herein, water-soluble aminated zinc oxide nanoparticles (ZnO NPs) were developed to effectively control the microbial spoilage in soybeans during soaking. ZnO NPs achieved significant inactivation of three dominant spoilage bacteria ( bacillus cereus , bacillus megaterium and enterococcus faecium ) isolated from the deteriorated soybeans, which could adhere to the bacterial surface and damage the cell wall/membrane, but also generate large amounts of reactive oxygen species (ROS). Compared to two commercial ZnO, water-soluble ZnO exhibited superior antibacterial properties due to producing more ROS and bacteria-adhered ability. After ZnO NPs treatment, the content of the residual Zn (51.1 mg/kg) in soybeans was the safety standards of Zn element in soybeans products for human). Therefore, the water-soluble ZnO NPs showed great potentials as efficient and safe antimicrobial agents for soybeans preservation during soaking process.
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PubMed
高影响因子
Arabian Journal of Chemistry
·
2023
·
IF 6
Zhujuan Li,Shuliang Chen,Futing Zi,Xianzhi Hu,Yunlong Chen
A fast and efficient Au (I) recovery adsorption method from an actual leaching solution of Cu 2+ -en-S 2 O 3 2- is presented. Aminophosphonic acid derivatized polyacrylonitrile fibers (PAN-NP), prepared with triethylenetetramine and phosphoric acid by chemical grafting, were used as the adsorbent. The adsorbent was well characterized by FT-IR, SEM, TGA and XPS. The effects of contact time, pH, temperature, and Au (Ⅰ) concentration were also investigated. PAN-NP can rapidly capture Au(S 2 O 3 ) 2 3– (20 min) and has a maximum adsorption capacity of 14.68 kg/t. Compared with -SH modified, PAN-NP has better stability and without oxidized. The adsorption process was described based on the Langmuir isothermal model ( R 2 > 0.99). Thermodynamic parameters indicated that the adsorption of Au(S 2 O 3 ) 2 3– on PAN-NP was exothermic ( ΔH θ = −9.906 kJ/mol) and adsorption mechanism involved a collective effect resulting the anion exchange of Au(S 2 O 3 ) 2 3– with –RNH 3 + H 2 PO 3 - , electrostatic attraction between –RNH 3 + and Au(S 2 O 3 ) 2 3– and complexation of P = O with Au (Ⅰ). Besides, PAN-NP-Au can be effectively eluted by sodium sulfite. Importantly, in the Cu 2+ -en-S 2 O 3 2- actual leaching solution, the PAN-NP can efficiently recover Au (I) with an adsorption percentage of up to 97 % at a the solidliquid ratio of 1:50, thereby affording a satisfactory application result. This is a meaningful method for recovering Au (Ⅰ) from thiosulfate solution.
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