JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2020
·Vol. 167
·期 4
·047514
·
IF 3.721
Yanyan Liu,Ruirui Xie,Peipei Yang,Ling Lu,Lin Shen,Jia Tao,Zhi Liu,Peng Zhao
Quercetin is one of the most important nutrients in human daily diet, the accurate and efficient analytical approaches for quercetin is highly required as it's closely related to many biological activities. In this paper, the three-dimensional highly porous gold film (hp-Au) modified gold electrode (Au) was prepared by a facile two steps self-templating method, it was found that hp-Au possess high surface-to-volume ratio and excellent conductivity. Combining with the multiple merits of hp-Au, the hp-Au/Au showed an excellent detection performance towards quercetin compared with bare electrode and Au nanoparticles modified gold electrode (AuNPs/Au), the detection limit was 3.9 nM in a wide concentration range from 20 nM to 100 μM. Meantime hp-Au/Au also showed decent stability, satisfied selectivity and desirable reproducibility. Moreover, the practical application of this sensor was verified by detecting QR in drink or food and medicine samples and the satisfactory recoveries of 97.43% to 101.59% and low RSD value (n = 3) no more than 3% were obtained.
研究领域:
分析化学
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食品科学
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药物分析
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2015
·
IF 4.513
Ye Zhu,Chuqing Zhou,Xupeng Yan,Yan Yan,Qiang Wang
In the present work, a highly sensitive and selective biosensor based on aptamer-functionalized nanoporous gold film (NPGF) was successfully developed for direct electrochemical detection of bisphenol A (BPA). NPGF was prepared by dealloying Ag from Au/Ag alloy leaf in concentrated nitric acid. The obtained NPGF was attached onto glassy carbon electrode and then was functionalized with BPA-specific aptamer via the formation of Au S bond. The fabrication of the sensor was characterized by scanning electron microscopy and X-ray photoelectron spectroscopy. NPGF exhibited excellent electrocatalytic activity towards the redox reaction of BPA, which ensured high sensitivity of the sensor. The aptamer-captured BPA showed a pair of redox peaks around 0.35/0.28 V (vs. Ag/AgCl). The experimental parameters in terms of aptamer concentration, reaction time, pH, and temperature were optimized. The calibration plot showed a linear range from 0.1 nM to 100 nM BPA with a remarkable detection limit of 0.056 ± 0.004 nM BPA. Particularly, the successful application of the developed sensor for the detection of BPA in human serum samples suggests its promising potential for clinical diagnosis.
研究领域:
分析化学
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生物传感器
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环境科学
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DOI
PubMed
高影响因子
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2012
·Vol. 59
·期 7
·879-883
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IF 0.678
Jing Zhou,Ying Xu,Le Wang,Jie Liu,Yamin Li,Baoxian Ye
An ultrastable chemical modified electrode (CME) was fabricated conveniently based on gold film by pulse plating of chloroauric acid on Pt disk electrode. As a novel modifying method of making CME, the CME was characterized by electrochemical impedance spectroscopy (EIS) and used as a voltammetric sensor for Ketamine. This thin gold film modified electrode exhibited excellent electrocatalysis to Ketamine oxidation. Based on this CME, detection of Ketamine by voltammetry was first erected with a fast-response and wide responding linear range. Further experiments demonstrated that this CME has good stability, repeatability and reproducibility. The established method is accurate, reliable, and can be used for the quality control of Ketamine hydrochloride injection.
研究领域:
分析化学
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电化学
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产品关联
DOI
高影响因子
Journal of Physical Chemistry C
·
2025
·
IF 3.2
Yulu Ye,Jiahang Zhou,Minqiang Xia,Yunbo Li
Membrane catalysts have garnered considerable attention in recent years owing to their outstanding stability, high recyclability, environmental compatibility, and convenience. Herein, nanogold membrane catalysts have been successfully fabricated with ultrathin gold nanowires in the presence of thiourea by a vacuum filtration deposition method aimed at facilitating charge transport and enhancing the catalytic performance. By maintaining the thiourea treatment concentration at 500 μg/mL, the catalytic time of the nanogold membrane remained below 1.0 min for 2-nitrophenol, specifically at 15 s. The 500 μg/mL thiourea-treated nanogold membranes are also capable of rapidly catalyzing the reduction of 4-nitrophenol, methylene blue, and methyl orange, causing their respective UV characteristic peaks to disappear expeditiously within 20 s. Overall, this novel method offers a simple and convenient approach to obtaining nanogold membrane catalysts, holding great potential promise for applications in materials, catalysts, and environment fields.
研究领域:
材料科学
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催化化学
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环境科学
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产品关联
DOI
高影响因子
ADVANCED ENGINEERING MATERIALS
·
2020
·Vol. 22
·期 4
·1901521
·
IF 3.217
Rongxiang He,Meilin Ruan,Yuyang Qi,Hongni Liu,Zhengtao Zhang,Chaohui Chen,Yiping Chao,Yumin Liu,Yong Chen
Droplet-based technologies, which utilize the surface charge characterization of droplets, are used in fluorescence-activated cell sorting and energy harvesting. Herein, the influence of droplet charges on microchips is investigated via surface engineering. An electrical field is applied to deflect the droplets in a microchannel, thereby enabling a qualitative analysis of the droplet charge. In a glass polydimethylsiloxane (PDMS)-boned microchip, the droplet charge decreases when the microchannel is changed from a single-sided to a three-sided rectangular microstructure. When the ionic concentration of the droplet increases from 1 μ m to 10 m m , droplet charges decrease by ≈78%. Meanwhile, a Au film is patterned in the microchannel, and 11-aminoundecanethiol hydrochloride (AUT) and 12-mercaptododecanoic acid (MDA) are modified to modulate the Au surface characterization. Compared with the glass–PDMS-bonded microchannel, the Au film can suppress the streaming potential to decrease the droplet charges. After modification with MDA and AUT, the droplet charges increase. Therefore, the microchannel structures, ionic concentration, and substrate surface properties can be utilized to modulate the droplet charges, which can be widely used in droplet-based energy harvesting and biological and chemical sample sorting.
研究领域:
生物技术
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材料科学
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微流体技术
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Xueling Shan,Qingyuan Song,Chang Su,Chunping Dong,Ding Jiang,Wenchang Wang,Zhidong Chen
Normally, analytical applications of metal oxide semiconductors (MOS) in electrochemiluminescence (ECL) sensors need to be coupled with electrochemical catalysts, some special coreactants or resonance energy transfer method, since MOS exhibited relatively low ECL intensity. In this research, we developed a simple ECL intensity enhancement method for MOS by covering a nanogold-film (NAuF) on the surface of fluorine-doped tin oxide-coated (FTO) conductive glass electrode. Aminated MnO 2 nanoparticles (NH-MnO 2 ) was chosen as exemplary MOS emitter to discuss the role of NAuF in ECL system. The results indicated that the NAuF bridged ECL sensor using NH-MnO 2 as emitter (NH-MnO 2 -NAuF/FTO) exhibited a stronger ECL intensity and extremely better stability. In furazolidone (FZD) determination test, the quenched ECL intensity showed a good linear relationship to FZD concentrations in the range 1.0 × 10 −8 M ∼ 1.0 × 10 −5 M, with a detection limit of 6.6 × 10 −9 M, in optimized conditions. Given these attributes, we developed a novel platform for ECL system that could simply enhance the intensity and stability. This work also efficiently offered insights into application potential of ECL analysis.
研究领域:
分析化学
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传感器技术
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2018
·
IF 4.244
Xi Su,Yi Xu,Huazhou Zhao,Shunbo Li,Li Chen
A microfluidic SERS chip integrated with blood separation and in-situ detection was designed and fabricated for the rapid detection of clinical blood samples. Each functional unit in the microfluidic SERS chip consist of separation-decantation cavity based on centrifugal separation principle, mixing channels and SERS detection chamber built with integrated nano-Au on Ag film microstructure. The serum creatinine was selected as a typical sample to demonstrate the capability of microfluidic SERS chip. It was found that the creatinine SERS characteristic peaks at 678 cm −1 can be effectively identified and the detection limit could be as low as 4.42 × 10 −3 μmol mL −1 in water. The blood samples were also tested in microfluidic SERS chip. The whole separation and test process could be completed within 2 min, which is a significant improvement in the field of creatinine detection. The whole blood of six cases clinical blood samples were also tested, and the results were consistent with the enzymatic results. The developed microfluidic SERS chip has advantages including reduction of the required quantity of blood sample, reusable and easy to operate. It is expected to provide a new method for rapid diagnostics .
研究领域:
生物医学工程
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分析化学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2020
·Vol. 8
·期 39
·20414-20419
·
IF 11.301
Mei Zhang,Ziqiang Wang,Hongjie Yu,Shengqi Wang,You Xu,Xiaonian Li,Liang Wang,Hongjing Wang
Electrocatalytic reduction of N2 is a promising alternative technology for the green and sustainable production of NH3. The development of this process is highly dependent on the identification of active electrocatalysts. Herein, a self-supported mesoporous Au-based film with sulfur decoration on Ni foam (S-mAu film/NF) has been synthesized by a micelle assembly replacement route. The obtained S-mAu film/NF exhibits superior electrochemical performance for nitrogen reduction reaction (NRR), resulting in a high NH3 yield (22.7 μg h−1 mgcat.−1) and Faraday efficiency (17.2%) under neutral conditions. This work offers a facile strategy for the synthesis of a self-supported mesoporous architecture with surface sulfur modification, which is favourable to the improvement of the electrocatalytic NRR performance.
研究领域:
电化学
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催化
·
材料科学
·
可持续化学
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产品关联
DOI
高影响因子
MOLECULES
·
2015
·Vol. 20
·期 4
·6299-6309
·
IF 2.416
Kun Guo,Rui Xiao,Xiaoye Zhang,Chaoguang Wang,Qiqi Liu,Zhen Rong,Lin Ye,Suhong Chen
Surface-enhanced Raman detection of thiram is demonstrated by using Ag-nanoparticles (Ag NPs) on Au film over nanosphere (AuFON) substrate as the hybrid substrate. The SERS signal of the Ag NPs attached to solid supports is studied. The close coupling together of thousands of Ag NPs on AuFON leads to the generation of hot spots for SERS. The Ag NPs on AuFON can be applied to detect rhodamine-6G (R6G) with the detection limitation of 10−11M and the pesticide thiram in acetone with a detection limit of as low as 0.24 ppm, which is much lower than the maximal residue limit (MRL) of 7 ppm in fruit prescribed by the U.S. Environmental Protection Agency (EPA). The hybrid substrates are shown to be highly sensitive for the detection of thriam, which produce highly enhanced Raman signals with good uniformity and reproducibility due to having plenty of hot spots on its surface.Keywords:SERS;Ag NPs;Au film over nanosphere;hybrid substrate;trace chemical detection
研究领域:
分析化学
·
环境科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Chenxi Wu,Huajun Lai,Feng Wang,Dianhui Wang,Weijiang Gan,Yulai She,Zhongmin Wang
V-based alloy membranes have huge potential for hydrogen separation and purification due to their higher hydrogen permeability , but suffer from hydrogen embrittlement . To address this matter, Pd and Fe have been chosen as alloying additions in V-based membranes to inhibit hydrogen embrittlement and maintain high hydrogen permeation performance based on the lattice-matching strategy. The phase structure, composition, microstructure and hydrogen permeation properties of V-Pd-Fe ternary alloy are investigated systematically, and the V-Fe and V-Pd binary alloys are presented for comparison. The results show that the prepared V-Pd-Fe ternary can match almost perfectly with pure V in lattice constants . Attributing to the lattice-matching strategy, the V-Pd-Fe ternary alloy exhibits more excellent hydrogen permeable properties than that of V-Fe and V-Pd binary alloys . The reduction of hydrogen embrittlement is ascribed to the lower hydrogen solubility that induced by the lattice distortion and electronegativity of Fe and Pd. Meanwhile, the manipulated lattice constant that parallel to pure V maintains high hydrogen permeation performance. Additionally, the designed ternary V 87.8 Pd 8 Fe 4.2 alloy exhibits exceptional long-term hydrogen permeation stability at 573 and 623 K, and hydrogen flux gradually decreases at 673 and 723 K is observed due to the interdiffusion between Pd film and V 87.8 Pd 8 Fe 4.2 substrate and defects in the Pd coating. This study offers new scenario and method for optimized hydrogen permeable properties and restrains hydrogen embrittlement in the alloy membrane.
研究领域:
材料科学
·
氢能与储能
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金属膜分离技术
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固态氢传输
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合金设计
·
物理冶金学
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DOI
高影响因子
Small
·
2019
·Vol. 15
·期 6
·1804769
·
IF 10.856
Hongjing Wang,Hongjie Yu,Ziqiang Wang,Yinghao Li,You Xu,Xiaonian Li,Hairong Xue,Liang Wang
Electrochemical reduction of N 2 to NH 3 provides an alternative strategy to replace the industrial Haber–Bosch process for facile and sustainable production of NH 3 . The development of efficient electrocatalysts for the nitrogen reduction reaction (NRR) is highly desired. Herein, a micelle-assisted electrodeposition method is presented for the direct fabrication of porous Au film on Ni foam (pAu/NF). Benefiting from its interconnected porous architectonics, the pAu/NF exhibits superior NRR performance with a high NH 3 yield rate of 9.42 µg h −1 cm −2 and a superior Faradaic efficiency of 13.36% at −0.2 V versus reversible hydrogen electrode under the neutral electrolyte (0.1 m Na 2 SO 4 ). The proposed micelle-assisted electrodeposition strategy is highly valuable for future design of active NRR catalysts with desired compositions toward various electrocatalysis fields.
研究领域:
电化学
·
催化
·
材料科学
·
可持续化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 11
·1-14
·
IF 5.3
Liu Yansheng,Sun Yukun,Jia Xiaobo,Zhou Jin,Li Kang,Li Zhaoxu,Wang Guofu
A method for detecting methamphetamine (MET), ketamine (KET), and morphine (MOP) molecules is presented using a reusable substrate based on SERS. The SERS substrate was prepared by etching the Au/Ag alloy film to synthesize a nanoporous Au membrane (AuNPM). By optimizing the preparation conditions and using rhodamine 6G (R6G) as an analyte, the AuNPM exhibited good SERS performance with a limit of detection (LOD) of 10 −9 mol L −1 . A competitive immunoassay category has been applied to the detection of MET, KET, and MOP. The MET, KET, and MOP antigens were functionalized on the surface of the AuNPM to specifically bind to the related drug antibodies. The Au nanoparticles (AuNPs) modified with 4-mercaptobenzoic acid (4-MBA) and antibodies against MET, KET, and MOP were used as nanotags. The 4-MBA served as the reporting molecule and drug antibodies were used to bind to free drug molecules in the target solution. The mixture of nanotags and target solution was dropped onto the antigen-modified AuNPM (antigen/AuNPM), and the free nanotags bind to the antigen/AuNPM. By comparing the SERS intensity of 4-MBA with the presence or absence of drug molecules, the drugs were qualitatively and quantitatively identified. Through this category, the LODs for detecting MET, KET, and MOP were 0.1, 1, and 1 ng mL −1 , respectively. This study proposes an effective method for constructing SERS-based detection of drug molecules with good potential for practical applications. Graphical abstract
研究领域:
分析化学
·
药物检测
·
纳米材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）