ACS Nano
·
2025
·
IF 16
Yufei Yao,Hongyang Qu,Zehui Sun,Yequan Chen,Shenglong Yang,Wei Ma
Oxygen reduction reaction (ORR) plays a crucial role in both the chemical and energy industries. Despite substantial advancements in theoretical, computational, and experimental studies, identifying both the in situ activity and selectivity in ORR electrocatalysis remains a major challenge. Here, using a suite of correlative operando scanning electrochemical probe and electrochemiluminescence microscopy techniques, we establish a link between the morphological structure and the local ORR activity and selectivity of single Au and Au@Pt platelets at the subparticle level. It is clearly shown that the edge facets of Au and Au@Pt platelets exhibit higher activity for 4e– ORR compared to basal planes, whereas the basal planes of both Au and Au@Pt platelets demonstrate superior 2e– selectivity relative to the edge facets. These findings deepen our understanding of ORR activity and selectivity across different facets at the subparticle level, which offers valuable guidance for the rational design of highly efficient ORR electrocatalysts.
研究领域:
电化学
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材料科学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Chen-Yang Han,Hai-Xiang Li,Bo Zhao,Mei-Na Chen,Zhencheng Chen,Guo-Cheng Han,Xiao-Zhen Feng,Heinz-Bernhard Kraatz
MicroRNA-21 (miRNA-21) is a class of small non-coding RNAs that play a crucial role in the regulation of post-transcriptional gene expression. By leveraging the principle of base complementary pairing, the detection of miRNA-21 can be achieved through its analogue, MicroDNA-21 (miDNA-21), which possesses an identical sequence. Utilizing screen-printed carbon electrodes (SPCE), a conducting polymer (polypyrrole, Ppy), and metal nanocomposites (gold-platinum nanoparticles, Au@Pt NPs) were sequentially electrodeposited to create an electrochemical biosensor for the detection of miDNA-21. This biosensor employed ferrocyanide/ferricyanide (Fe(CN) 6 3−/4− ) as the electrochemical signaling probe, and its structure was elucidated via field emission scanning electron microscopy (FESEM) and Energy Dispersive Spectrometer (EDS). Quantitative detection was facilitated through differential pulse voltammetry (DPV), yielding a concentration range and linear fitting equation of 10.00–7.00 × 10.00 −14 mol/L: ΔI = 0.5143 lg c + 9.191, R 2 = 0.9986. The limit of detection (LOD) was determined to be 2.90 × 10 −15 mol/L, with a sensitivity of 9.42 μA/μmol/L·cm 2 . Subsequent performance assessments confirmed the sensor’s excellent selectivity, reproducibility, and stability. Evaluation using the standard addition method, with normal human serum as the matrix, yielded recoveries ranging from 98.97 % to 102.70 %, and relative standard deviation (RSD) values below 1.00 %. These results demonstrate the method’s viability for practical application in detecting miRNA in human serum.
研究领域:
生物化学
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医学诊断
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材料科学
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DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2014
·Vol. 18
·期 9
·2487-2496
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IF 2.234
Wang Zhihua,Li Jinshu,Xu Lijuan,Feng Yanjun,Lu Xiaoquan
A sensitive and selective imprinted electrochemical sensor for the determination of aflatoxin B 1 (AFB 1 ) was constructed on a glassy carbon electrode by stepwise modification of functional multiwalled carbon nanotubes (MCNTs), Au/Pt bimetallic nanoparticles (Au/PtNPs), and a thin imprinted film. The fabrication of a homogeneous porous poly o -phenylenediamine (POPD)-grafted Au/Pt bimetallic multiwalled carbon nanotubes nanocomposite film was conducted by controllable electrodepositing technology. The sensitivity of the sensor was improved greatly because of the nanocomposite functional layer; the proposed sensor exhibited excellent selectivity toward AFB 1 owing to the porous molecular imprinted polymer (MIP) film. The surface morphologies of the modified electrodes were characterized using a scanning electron microscope. The performance of the imprinted sensor was investigated by cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy in detail. A linear relationship between the sensor response signal and the logarithm of AFB 1 concentrations ranging from 1 × 10 −10 to 1 × 10 −5 mol L −1 was obtained with a detection limit of 0.03 nmol L −1 . It was applied to detect AFB 1 in hogwash oil successfully.
研究领域:
分析化学
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食品安全检测
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纳米材料应用
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2016
·
IF 4.509
Yajie Xu,Lingli Liu,Hanbao Chong,Sha Yang,Ji Xiang,Xiangming Meng,Manzhou Zhu
AuPt alloy nanoparticles (NPs) were facilely synthesized with oleylamine as the stabilizing ligand and characterized by high-resolution transmission electron microscopy, powder X-ray diffraction, inductively coupled plasma-atomic emission spectrometer analysis, and so on. In addition, the AuPt alloys supported by the nano CeO2 exhibit high selectivity and efficiency in hydrogenation of benzylidene acetone under ambient temperature and pressure. By analyzing the catalytic performance over the NPs with different Au:Pt compositions, we found that the TONPt values (based on the number of Pt atoms) vary in the same trend with the change of conversion. Despite that gold itself shows no catalytic activity, the improved conversion and TONPt with the alloy catalysts clearly show the promotion effect of gold on the catalytic activity of the platinum. The inactive metal significantly improves the catalytic activity of active metal, which shows that the AuPt alloy exhibits an interesting synergistic effect.
研究领域:
化学
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材料科学
·
催化研究
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Junkui Li,Chen Li,Wang Guo,Yiqing Guo,Xiaobo Zou,Zongbao Sun
The development of a capsaicin detection system that integrates facile preliminary evaluation with high sensitivity and accuracy across a wide detection range is crucial for the discrimination of gutter oil and the protection of human health. In this study, we constructed a novel colorimetric/SERS dual-mode detection system utilizing peroxidase-like Au@Pt nanoparticles (NPs) that exhibit SERS-activity. The Au@Pt NPs feature a spherical gold nanoparticle core with synapse-like platinum nanoparticles distributed intermittently on their surface, this structure enhances the catalytic activity of the PtNPs and the SERS activity of the AuNPs, making them ideal for designing colorimetric/SERS dual-mode probes. Based on the colorimetric assay, we achieved a capsaicin detection range from 1 to 10,000 μM, with a limit of detection (LOD) of 3.48 μM, as determined by absorption spectroscopy analysis. Additionally, a linear calibration curve for capsaicin ranging from 10 −9 to 10 −5 M was established using the SERS method, yielding an LOD of 7.38 nM. By integrating the advantages of facile detection through colorimetric analysis with the high-sensitivity trace assay provided by SERS, this proposed dual-mode detection system demonstrates excellent sensitivity, reliability, selectivity, and wide detection range compared to previous probes and methods. Consequently, this method can serve as an efficient tool for monitoring oil quality.
研究领域:
分析化学
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食品安全
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
·
2018
·
IF 2.207
Xiong-Fei Zhang,Zhongguo Wang,Yuxia Zhong,Jianhao Qiu,Xingguang Zhang,Yuan Gao,Xiaoli Gu,Jianfeng Yao
In this study, homogeneous alloy Au Pt nanoparticles were successfully immobilized on ultrathin TiO 2 nanorods via a facile photodeposition technique. The Au Pt/TiO 2 hybrid exhibited high photocatalytic activity and stability during the selective photosynthesis of benzaldehyde from benzyl alcohol under visible light . The optimal performance was obtained with the Au 1 Pt 1 /TiO 2 sample, which had a benzyl alcohol conversion rate of 65.3%. The engineered TiO 2 nanorods (304 m 2 /g) can be employed as a stabilizing matrix and an excellent dispersant for noble metal particles. Moreover, the formation of the alloy structure substantially enhances the photoinduced carrier separation efficiency compared with loading Au or Pt alone on TiO 2 . The bimetallic nanoparticles exhibited the properties related to the individual metals, as well as new properties due to synergistic effects of the electron-accumulating function of Pt and the surface plasmon resonance of Au.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 61
·35887-35894
·
IF 3.049
Ting Bian,Biao Sun,Sai Luo,Long Huang,Shan Su,Chunfeng Meng,Shichuan Su,Aihua Yuan,Hui Zhang
Pt-based nanocrystals with a twinned structure are highly desirable to achieve high performances in both catalytic activity and durability for methanol oxidation reaction (MOR). However, it still remains great challenge for producing such twinned nanocrystals due to the high internal strain energy of Pt. Here we present a seed-mediated approach to generate Au@PtCu nanostars with a five-fold twinned structure using Au decahedra as seeds. The composition of Pt/Cu in the nanocrystals was tuned by varying the molar ratio of Pt to Cu salt precursors with the amount of Au seeds being the same. Through composition optimization, Au@Pt1.2Cu nanostars achieved the highest specific (1.06 mA cm−2) and mass (0.18 mA mgPt−1) activities for MOR, which were about 5.9 and 1.6 times higher than those of commercial Pt/C, respectively. After accelerated stability test (ADT) for 1500 cycles, such nanostars remained ∼95% of specific activity compared to a loss of ∼28% for commercial Pt/C, indicting their superior durability for MOR. We believed that this enhancement may arise from the unique twinned structure and possible synergetic effect between Pt and Cu components.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 7
·1-10
·
IF 5.3
Gao Bao,Ding Yu,Cai Zhihe,Wu Shi,Wang Juan,Ling Na,Ye Qinghua,Chen Moutong,Zhang Youxiong,Wei Xianhu,Ye Yingwang,Wu Qingping
A dual-recognition strategy is reported to construct a one-step washing and highly efficient signal-transduction tag system for high-sensitivity colorimetric detection of Staphylococcus aureus ( S. aureus ). The porous (gold core)@(platinum shell) nanozymes (Au@PtNEs) as the signal labels show highly efficient peroxidase mimetic activity and are robust. For the sake of simplicity the detection involved the use of a vancomycin-immobilized magnetic bead (MB) and aptamer-functionalized Au@PtNEs for dual-recognition detection in the presence of S. aureus. In addition, we designed a magnetic plate to fit the 96-well microplate to ensure consistent magnetic properties of each well, which can quickly remove unreacted Au@PtNEs and sample matrix while avoiding tedious washing steps. Subsequently, Au@PtNEs catalyze hydrogen peroxide (H2O2) to oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) generating a color signal. Finally, the developed Au@PtNEs-based dual-recognition washing-free colorimetric assay displayed a response in the range of S. aureus of 5 × 10 1 –5 × 10 5 CFU/mL, and the detection limit was 40 CFU/mL within 1.5 h. In addition, S. aureus -fortified samples were analyzed to further evaluate the performance of the proposed method, which yielded average recoveries ranging from 93.66 to 112.44% and coefficients of variation (CVs) within the range 2.72–9.01%. These results furnish a novel horizon for the exploitation of a different mode of recognition and inexpensive enzyme-free assay platforms as an alternative to traditional enzyme-based immunoassays for the detection of other Gram-positive pathogenic bacteria. Graphical abstract
研究领域:
生物化学
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纳米医学
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微生物学
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产品关联
DOI
PubMed
高影响因子
Sustainable Energy & Fuels
·
2020
·Vol. 4
·期 9
·4878-4883
·
IF 5.503
Hongjie Yu,Ziqiang Wang,Zechuan Dai,Qiqi Mao,You Xu,Xiaonian Li,Liang Wang,Hongjing Wang
Porous metal catalysts are considered as excellent catalysts for water electrolysis because of their large surface area, tunable pore size, abundant active sites and facilitated charge/mass transfer channels. Herein, a Au3Pt alloy film with interconnected network pores was in situ grown on Ni foam (pAu3Pt/NF) by a micelle-assisted replacement route. Benefiting from the interwoven network porous structure and bimetallic component, pAu3Pt/NF exhibits remarkable electrocatalytic HER activity that delivers an overpotential of −40.1 mV at a current density of 50 mA cm−2 with a Tafel slope of 42.3 mV dec−1 in 1.0 M KOH electrolyte. The proposed strategy paves the way to the rational design of self-supporting interwoven network porous nanomaterials for high-efficiency water electrolysis and beyond.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2009
·
IF 5.712
Jingming Gong,Ting Zhou,Dandan Song,Lizhi Zhang,Xianluo Hu
A new, highly sensitive and selective sensor for the electrochemical assay of Hg(II) by anodic stripping voltammetry has been developed, whereby a glassy carbon electrode is modified with a novel inorganic−organic hybrid nanocomposite, namely, bimetallic Au−Pt nanoparticles/organic nanofibers (labeled as Au−PtNPs/NFs). The sensor possesses a three-dimensional (3D) porous network nanoarchitecture, in which the bimetallic Au−Pt NPs serving as metal NP-based microelectrode ensembles are homogenously distributed in the matrix of interlaced organic NFs. The surface structure and composition of the sensor were characterized by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). Its electrochemical performance was systematically investigated. Our results show that such a newly designed, Au−PtNPs/NF nanohybrid modified electrode provides remarkably improved sensitivity and selectivity for the stripping assay of Hg(II). The detection limit is found to be as low as 0.008 ppb (S/N = 3) that is much below the guideline value from the World Health Organization (WHO). Interferences from other heavy metal ions such as Cu(II), Cr(III), Co(II), Fe(II), Zn(II), and Mn(II) ions associated with mercury analysis are effectively inhibited. Toward the goal for practical applications, the sensor was further evaluated by monitoring Hg(II) in tap and river water specimens.
研究领域:
分析化学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 106
·87061-87068
·
IF 3.84
Pei Song,Shan-Shan Li,Li-Li He,Jiu-Ju Feng,Liang Wu,Shu-Xian Zhong,Ai-Jun Wang
In this work, bimetallic Au–Pt alloyed nanowire networks (AuPt NNs) were facilely synthesized by a simple and rapid one-pot wet-chemical method on a large-scale, using N-methylimidazole as a structure-directing agent and a weak stabilizing agent. The surface of AuPt NNs was clean owing to the easy removal of the adsorbed N-methylimidazole. The control experiments demonstrated that the morphologies of AuPt NNs were strongly correlated with the amount of N-methylimidazole and reaction temperature. The formation mechanism included the four-stage growth processes: rapid nucleation, selective adsorption, π–π induced assembly, and oriented attachment growth. The as-synthesized AuPt NNs exhibited enhanced electrocatalytic activity and improved stability for methanol oxidation reaction (MOR) and oxygen reduction reaction (ORR) as compared to commercial Pt black and individual Pt nanoparticles.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2021
·
IF 4.464
Haolin Xiao,Liangli Cao,Huishan Qin,Shanshan Wei,Miao Gu,Feijun Zhao,Zhencheng Chen
Lactic acid (LA) is an energy product of anaerobic metabolism and also used as an important biomarker in clinical medical diagnosis. Herein, a facile and efficient non-enzymatic electrochemical sensor had been successfully developed to determine LA using gold platinum bimetallic nanoparticles modified molybdenum disulfide nanosheet (MoS 2 -AuPt) as a sensing platform. The presence of AuPtNPs not only increased the electron transfer rate but also could replace enzymes for electrochemical oxidation of LA. Thus, MoS 2 -AuPt could be acted as an efficient electrocatalyst for non-enzymatic LA detection. Finally, the non-enzymatic LA sensor was used to detect different concentrations of LA, its linear range was 0.005–3 mM, the detection limit was 0.00033 mM, and the response time was less than 15 s. Moreover, the developed LA sensor had been successfully applied to detect LA in human sweat, which provided a broad prospect for the analysis of LA in some other complicated samples.
研究领域:
生物医学工程
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）