ChemCatChem
·
2019
·Vol. 11
·期 6
·1779-1788
·
IF 4.495
Wei Zhang,Ziqiang Xiao,Jiajun Wang,Wenqin Fu,Rong Tan,Donghong Yin
Graphical Alloys of Catalysis ! Synergistic effect in Au−Pd alloy catalysts enhanced selective aerobic oxidation of alcohols using air at atmospheric pressure in water. A series of bimetallic Au−Pd alloy nanoparticles (NPs) with varied Au/Pd molar ratios was supported on Gamma-alumina (γ-Al 2 O 3 ) surface through the co-impregnation-reduction method using HAuCl 4 and PdCl 2 as metal precursors. Characterization results suggested the high dispersion of Au−Pd alloy NPs, as well as the interplay between the two compositions. Benefitting from the synergistic effects of Au−Pd alloying, the bimetallic Au-Pd x @γ-Al 2 O 3 catalysts were highly efficient for selective aerobic oxidation of various alcohols either aromatic or aliphatic in water using air at atmospheric pressure as a sole oxidant without the need for any cocatalyst. Quantitative yields of corresponding aldehydes or ketones were achieved over Au-Pd 1.2 @γ-Al 2 O 3 within 2 h, whereas pure Au@γ-Al 2 O 3 or Pd@γ-Al 2 O 3 was far less efficient. More importantly, the “alloying effect” appeared to stabilize the bimetallic NPs against aggregation and poisoning, which made the Au-Pd x @γ-Al 2 O 3 more stable and reusable in the aerobic oxidation of alcohols.
研究领域:
化学
·
催化材料科学
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DOI
高影响因子
ANALYST
·
2022
·Vol. 147
·期 24
·5655-5662
·
IF 5.227
Ying Zhou,Ruichun Li,Guomei Zhang,Yan Zhang,Caihong Zhang,Shaomin Shuang
Metal–organic frameworks (MOFs) have emerged as interesting nanomaterials owing to their large surface area, high porosity, tunable pore architecture and easy functionalization. However, an inferior electrical conductivity hinders their application in electrochemical sensing. In this paper, gold–palladium alloy/UiO-66-NH2/graphene (AuPd/UiO-66-NH2/GN) composites were synthesized by loading alloys on the surfaces of MOFs and then attaching them to the graphene surface. The addition of metal nanoparticles and graphene enhanced the electron transfer ability of MOFs. Then, composites were used to modify a glassy carbon electrode (GCE) to construct a sensitive dopamine (DA) electrochemical sensor. The developed sensor manifested two linear relationships in lower concentration ranges and in higher concentration ranges with a 0.21 × 10−6 mol L−1 low detection limit (3σ/k) under optimal conditions. The results certified that the constructed sensor had high selectivity, excellent reproducibility and good stability, and had been used successfully for DA detection in actual human serum samples.
研究领域:
材料科学
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分析化学
·
生物医学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Jin Wang,Peina Zhang,Yujiao Xiahou,Dayang Wang,Haibing Xia,Helmuth Möhwald
The present work introduces a new way to prepare Au–Pd alloy nanowire networks (NWNs) via deposition of Pd atoms onto Au nanowires in reaction media at room temperature without the aid of additional reducing agents. Thanks to their excellent colloidal stability in water as well as in ethanol, the resulting NWNs can be utilized to produce composite thin films with Nafion (perfluorinated sulfonic acid) with dimensions above dozens of square centimeters by means of solution casting on the glass substrate. Most importantly, these films can be easily transferred onto different solid substrates by lift-off technology. Moreover, the resulting Au–Pd alloy NWNs can also be easily and thoroughly loaded into macroscopic carbon fiber cloth (CFC). Both the Au–Pd alloy NWN/Nafion composite film and the Au–Pd alloy NWN-loaded CFC can be used as flexible electrodes for electrocatalysis of ethanol oxidation, with electrocatalytic performance at different distorted states superior by 2 orders of magnitude to those reported in the literature (e.g., commercial Pd/C catalysts and Pd-based nanostructured catalysts). This work opens new possibilities for the large-scale manufacturing of electrodes for fuel cells.
研究领域:
材料科学
·
电化学
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DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-18
·
IF 14.7
Meng Xiangqin,Fan Huizhen,Chen Lei,He Jiuyang,Hong Chaoyi,Xie Jiaying,Hou Yinyin,Wang Kaidi,Gao Xingfa,Gao Lizeng,Yan Xiyun,Fan Kelong
Developing strategies that emulate the killing mechanism of neutrophils, which involves the enzymatic cascade of superoxide dismutase (SOD) and myeloperoxidase (MPO), shows potential as a viable approach for cancer therapy. Nonetheless, utilizing natural enzymes as therapeutics is hindered by various challenges. While nanozymes have emerged for cancer treatment, developing SOD-MPO cascade in one nanozyme remains a challenge. Here, we develop nanozymes possessing both SOD- and MPO-like activities through alloying Au and Pd, which exhibits the highest cascade activity when the ratio of Au and Pd is 1:3, attributing to the high d-band center and adsorption energy for superoxide anions, as determined through theoretical calculations. The Au 1 Pd 3 alloy nanozymes exhibit excellent tumor therapeutic performance and safety in female tumor-bearing mice, with safety attributed to their tumor-specific killing ability and renal clearance ability caused by ultrasmall size. Together, this work develops ultrasmall AuPd alloy nanozymes that mimic neutrophil enzymatic cascades for catalytic treatment of tumors.
研究领域:
生物医学工程
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肿瘤学
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
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2022
·Vol. 24
·期 3
·1-15
·
IF 2.533
Zhang Haifeng,Zhang Gongguo,Zheng Yiqun,Zhao Na,Ma Yanyun,Liu Feng,Liu Maochang
Gold–palladium (AuPd) alloy nano-corolla are successfully prepared in high purity, followed by exploration as electrocatalysts for electroxidation of ethanol (EOR) in alkaline medium. Applying kinetics control on the one-pot formation process using a syringe pump is emphasized, where the Au/Pd precursor solution is dropwise titrated into the reaction mixture containing capping agent and reductant at an elevated temperature. We perform systematical investigation towards the morphology evolution pathway and effects of several key parameters. After loading on carbon black, the current AuPd alloy nano-corolla exhibit superb specific activity, reaction kinetics, and operation stability for EOR, showing morphological and structural merit. The present study provides insight into fabrication of bimetallic alloy nanocrystals with open structure, which could find important use in crystal engineering for multimetallic nanocrystals and rational design of fuel cell electrocatalyst. Graphical abstract Gold–palladium (AuPd) alloy nanocrystals in the form of corolla are successfully prepared via kinetic-controlled synthesis in high purity, exhibit improved activity and stability as EOR electrocatalysts in KOH solution
研究领域:
材料科学
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电化学
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催化科学
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DOI
高影响因子
MICROCHEMICAL JOURNAL
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2025
·
IF 5.1
Tianwen Liu,Wei Yuan,Mengyao Si,Xiaoning Wang,Xiangping Liu,Xiaoying Wang
The concentration fluctuations of cellular-myelocytomatosis oncogene (c-Myc) protein may be related to a variety of tumors such as lymphoma, therefore, detection of abnormal trace-level changes is of great significance for early predictions. Conventional detection methods suffer from time-consuming analytical processes and insufficient sensitivity. Thus, the development of a sensitive detection method for c-Myc protein in blood is particularly crucial. We developed an electrochemical sensor for the sensitive detection of c-Myc protein based on gold–palladium alloy nanoparticles (AuPd NPs), leveraging its dual-function for both electrode modification and signal tag. Specifically, AuPd NPs were rapidly formed on the electrode surface by electrodeposition techniques to anchor the capture antibodies (Ab I ), which can increase the conductivity and load capacity of the electrode. Subsequently, using toluidine blue (TB) as a reducing agent, TB-AuPd was synthesized in one step, and further utilized to anchor the detection antibodies (Ab II ), which improved the load quantity and electrocatalytic activity of TB. When the target was present, the sandwich sensor was successfully constructed, benefiting from dual amplifications to achieve sensitive detection of c-Myc protein. Eventually, the proposed sensor exhibited a wider linear range (1–1000 pg mL −1 ) and a lower detection limit (0.5 pg mL −1 , S/N = 3). The developed method demonstrated strong concordance with commercially available ELISA kits, with no statistically significant difference observed in detection results. Thus, the proposed sensor realized sensitive detection of c-Myc protein, and can render valuable guidance for prospective clinical test applications.
研究领域:
生物医学工程
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肿瘤学
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分析化学
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DOI
高影响因子
CATALYSIS TODAY
·
2022
·
IF 6.562
Peng Bai,Tao Zhou,Xiaohua Wang,Xiaofei Liu,Yi Wang,Yue Wang,Edgar Muhumuza,Yonghui Zhang,Pingping Wu
A series of γ-Al 2 O 3 supported gold-palladium (Au-Pd) alloy nanoparticles (NPs) catalysts were synthesized by a one-pot approach applying mercapto-propyl-trimethoxysilane (MPTMS) as an anchoring ligand. Homogeneously dispersed Au-Pd alloy NPs were observed on the prepared catalysts and their catalytic performance in benzyl alcohol partial oxidation was investigated. Results showed that the highest benzaldehyde yield was achieved on catalyst Au-Pd/7%MPTMS-γ-Al 2 O 3 with a benzaldehyde selectivity of 90%. By establishing the structure-performance relationship, the high activity of catalysts with MPTMS modification was attributed to the anchoring and dispersion effect of MPTMS on Au-Pd NPs, while the high benzaldehyde selectivity was due to the formation of more surface Lewis acid sites after introducing MPTMS, protecting the benzaldehyde from over-oxidation to byproducts.
研究领域:
催化化学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF CATALYSIS
·
2024
·
IF 6.5
Hang Li,Kaisheng Yao,Tianhang Liu,Tianhang Han,Qi Wang,Aozhou Wang,Weiwei Lu
Bimetallic AuPd plasmonic photocatalyst is a promising candidate for catalyzing selective oxidation of aromatic alcohol. However, developing a simple one-step method for the preparation of free-standing AuPd nanostructures with excellent photocatalytic performance remains a huge challenge. Here, a facile liquid–liquid interface route was exploited to one-pot prepare free-standing AuPd alloy nanowires (NWs) under mild conditions. Specifically, Au 1 Pd 1 NWs are grown via oriented attachment at chloroform-water interface and 40 °C with Na 2 PdCl 4 and HAuCl 4 as precursors and 1-naphthol as reductant. Au 1 Pd 1 NWs possess many advantages, such as thin diameter (4.0 nm), large aspect ratio, abundant defects and strong Au-Pd electronic interaction. During benzyl alcohol oxidation to benzaldehyde, Au 1 Pd 1 NWs exhibit excellent photocatalytic activity and durability. At 40 min of visible light illumination, 98 % conversion of benzyl alcohol and 100 % selectivity to benzaldehyde are finished. After five cycles, Au 1 Pd 1 NWs still maintain high photocatalytic activity. Compared to pure Au NWs, alloying Pd with Au in Au 1 Pd 1 NWs dramatically enhances photocatalytic activity. The results indicate that the generated abundant •O 2 – under illumination play an important role in significantly improving benzyl alcohol oxidation to benzaldehyde.
研究领域:
材料科学
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催化化学
·
纳米技术
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Weiwei Chen,Fan Yang,Xi Chen,Cheng Jin,Ninghong Yin,Mengya Sun,Yinbang Zheng,Ke Yang,Zefeng Wang,Dinggeng He,Li Wang,Luo Hai
An ultrasmall bimetallic Au2Pd3 nanozyme with self-cascade enzyme-like activities and robust photothermal heating properties is synthesized and encapsulated into a poly(vinyl alcohol)/hyaluronic acid (PVA/HA) matrix via a repeated freezing and thawing process to yield a hydrogel microneedle patch (Au2Pd3@PH). This microneedle displays a good tissue-piercing capability and thermal-responsive melting behavior. Upon exposure to an 808 nm near-infrared laser, Au2Pd3@PH dissolves and releases Au2Pd3, which shows glucose oxidase (GOx)-like catalytic activity for the conversion of endogenous glucose into gluconic acid and hydrogen peroxide (H2O2), thereby reducing the glucose level and local pH at the wound site. The reduced pH induces the peroxidase-like activity of Au2Pd3 to further oxidize H2O2 into the hydroxyl radical (•OH). In vitro experiments reveal that Au2Pd3@PH exhibits antibacterial rates exceeding 99% against both Staphylococcus aureus and Salmonella typhimurium, showing a photothermal/chemodynamic dual-mode synergistic antibacterial effect. Further in vivo assays demonstrate that the Au2Pd3@PH treatment group achieves near-complete healing of infected diabetic wounds within 7 days, indicating an enhanced wound healing process. The treatment with Au2Pd3@PH effectively modulates inflammatory factor expression, including marked downregulation of TNF-α and IL-6, while simultaneously promoting collagen deposition and angiogenesis, with no adverse biological effects observed. Therefore, the proposed Au2Pd3@PH hydrogel microneedle provides a promising strategy for treating diabetic wound infections with a high performance.
研究领域:
生物医学工程
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纳米医学
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感染性疾病治疗
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创伤修复与再生医学
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免疫调节
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炎症调控
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转化医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Xuefei Chen,Hanlu Guo,Zhiwei Hu,Lei Dong,Jianhua Shen,Yihua Zhu,Chunzhong Li
Developing photocatalytic systems capable of simultaneously synthesizing value-added heterocycles and producing green hydrogen is of great importance for solar-driven chemical transformations and sustainable manufacturing. In this work, we report a highly efficient bifunctional photocatalyst composed of Au 4 Pd 5 alloy nanoparticles anchored on nitrogen-doped TiO 2 (N-TiO 2-x ), wherein the reinforced Pd Lewis acidic (LA) sites and reinforced O Lewis basic (LB) sites synergistically activate o-phenylenediamine (OPD) and ethanol, respectively. This cooperative interaction facilitates a single-intermediate pathway (ethanol - ethoxy radical - acetaldehyde), leading to the selective formation of 2-methylbenzimidazole (2MBZ) and concurrent H 2 evolution. Under optimal conditions, the system achieves a 2MBZ yield of 3.80 mmol·g −1 ·h −1 , H 2 generation rate of 14.17 mmol·g −1 ·h −1 , and a selectivity of 94.43 %, outperforming all previously reported photocatalytic systems to date. Mechanistic insights derived from in-situ characterizations, and density functional theory (DFT) calculations reveal that electron redistribution at the Au-Pd interface and oxygen vacancy (O v ) induced charge modulation in N-TiO 2-x are responsible for the enhanced charge separation, reactant adsorption, and activation. The system maintains excellent performance under natural sunlight, with H 2 and 2MBZ production rates of 11.96 and 3.11 mmol·g −1 ·h −1 , respectively, which will be more economical than the conventional thermal route and demonstrating strong scalability.
研究领域:
光催化
·
材料化学
·
可持续能源
·
有机合成
·
多相催化
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）