Journal of Nanomaterials
·
2014
·
IF 1.611
Wang Li,Fa-gen Li,Jun Wang,Guo-meng Zhao
Uniform magnetic hollow nanospheres (GdNi2, Co5Gd) coated with Gd2O3 have been successfully prepared on a large scale via a urea-based homogeneous precipitation method using silica (SiO2) spheres as sacrificed templates, followed by subsequent heat treatment. Nitrogen sorption measurements and scanning electron microscope reveal that these hollow-structured magnetic nanospheres have the mesoporous shells that are composed of a large amount of uniform nanoparticles. After reduction treatment, these nanoparticles exhibit superparamagnetism that might have potential applications in medicine. Furthermore, the developed synthesis route may provide an important guidance for the preparation of other multifunctional hollow spherical materials.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2013
·
IF 1.941
Songbai Liu,Kuo Jiang,Hongbo Zhang,Yi Liu,Li Zhang,Bingye Su,Yibao Liu
Ceramics with structure on nanometer-length scales have a thermal conductivity much lower than their coarser-grained ceramics. But the relatively low activation energy for grain growth of nanoparticles limits the stability of nano-material at high temperatures. The objective of the present study was to investigate the preparation of the composite powders of nano (La,Gd) 2 Zr 2 O 7 and nano (Zr,Gd)O 2 − δ by a sol-spray pyrolysis method. The XRD results indicated that the reaction products of 0.2LaO 1.5 –xGdO 1.5 –(0.8 − x)ZrO 2 (0.15 ≤ × ≤ 0.25) ternary system were composed of pyrochlore (La,Gd) 2 Zr 2 O 7 and cubic (Zr,Gd)O 2 phases. The composition with 0.2LaO 1.5 –0.2GdO 1.5 –0.6ZrO 2 had a grain size much smaller than the lower GdO 1.5 content counterpart for both the (La,Gd) 2 Zr 2 O 7 and (Zr,Gd)O 2 − δ phases. The relationship between grain size and GdO 1.5 content was explained in terms of lattice matching.
研究领域:
材料科学
·
陶瓷学
✓ 已验证
产品关联
DOI
高影响因子
Molecular Imaging
·
2016
·
IF 2.216
Pu Zhang,Zhide Guo,Deliang Zhang,Chang Liu,Guibing Chen,Rongqiang Zhuang,Manli Song,Hua Wu,Xianzhong Zhang
The aim of this study is to develop a copolymer-based single-photon emission computed tomography/magnetic resonance (SPECT/MR) dual-modality imaging agent that can be labeled with both technetium-99m (99mTc) and gadolinium (Gd) and target asialoglycoprotein receptor (ASGPR) via galactose. Monomers of N-p-vinylbenzyl-6-(2-(4-dimethylamino)benzaldehydehydrazono) nicotinate (VNI) for labeling of 99mTc, 5,8-bis(carboxymethyl)-3-oxo-11-(2-oxo-2-((4-vinylbenzyl)amino)ethyl)-1-(4-vinylphenzyl)-2,5,8,11-tetraazatridecan-13-oic acid (V2DTPA) for labeling of Gd, and vinylbenzyl-O-β-d-galactopyranosyl-d-gluconamide (VLA) for targeting ASGPR were synthesized, respectively. Then the copolymer P(VLA-co-VNI-co-V2DTPA) (pVLND2) was synthesized and characterized by gel permeation chromatography, dynamic light scattering, and high-performance liquid chromatography analysis. After labeling with 99mTc and Gd simultaneously, the radiochemical purity, toxicity, relaxivity (r1), and in vivo SPECT/MR imaging in mice were evaluated. Single-photon emission computed tomography/magnetic resonance imaging and biodistribution results showed that pVLND2 could target ASGPR well. The significantly improved signal to noise ratio was observed in mice liver during MR imaging. All the results suggest that this novel kind of copolymer has the potential to be further developed as a functional SPECT/MR imaging agent.
研究领域:
医学影像学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2014
·
IF 4.287
ChengCai Zeng,XiaoNi Shi,Bo Wu,Dong Zhang,WeiLu Zhang
A type of novel macromolecular colloid was prepared from gadolinium-based poly( l -succinimide) and gold nanoparticles (GNPs) with Au S covalent bonds. The colloid displayed improved stability in aqueous media and regular arrays in partial region. Moreover, these materials enhanced the contrast 9 times more than that of the corresponding uncoated Au compound when the Au mass content was only 0.15%. Therefore, these materials might have potential as dual-modality contrast agents for magnetic resonance imaging (MRI) and computed tomography (CT).
研究领域:
医学影像学
·
纳米医学
✓ 已验证
DOI
高影响因子
Small
·
2021
·Vol. 17
·期 52
·2105683
·
IF 13.281
Lingfeng Gao,Lude Wang,Artem V. Kuklin,Jie Gao,Shouchun Yin,Hans Ågren,Han Zhang
The present work demonstrates a facile hydrothermal approach to synthesize lanthanide-doped carbon quantum dots (CQDs) with europium and/or gadolinium elements. Taking the advantage of broadband adsorption in the ultraviolet-visible region, the doped QDs are directly used as building blocks for photo-electrochemical (PEC)-type photodetectors (PDs) and their performance is systematically investigated under various conditions. The europium (Eu) and gadolinium (Gd) co-doped (C:EuGd) QDs exhibit better photo-response than the single-elemental doped ones and also show outstanding long-term stability. According to the apparent response to light from 350 to 400 nm, the C:EuGd QDs are demonstrated to hold great potential for narrow-band PDs. This work highlights the practical applications of lanthanide-doped CQDs for PDs, and the results are beneficial for the development of elemental-doped CQDs in general.
研究领域:
材料科学
·
光电器件
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2020
·
IF 4.189
Lixin Zang,Huimin Zhao
Metalloporphyrins are suitable for medical oxygen sensing without disturbance to local tissue environment. To understand the correlation between the first triplet-state (T1) energy of metalloporphyrins and their phosphorescence responses to oxygen, the luminescence and oxygen sensing properties of two porphyrins (hematoporphyrin monomethyl ether, HMME; tetraphenylporphyrin, TPP) coordinated to gadolinium(III) (Gd) were studied comparatively. The absorption and luminescence of Gd-TPP are red-shifted relative to that of Gd-HMME, indicating that Gd-TPP has a lower T1 energy. The phosphorescence quantum yield (ΦP) of Gd-TPP is ∼10% of that of Gd-HMME. The large difference in ΦP is due to the increased nonradiative decay rate of T1 in Gd-TPP, as demonstrated by a shorter phosphorescence lifetime. The oxygen response (KSV) is related to the unquenched phosphorescence lifetimes (τ0) and oxygen quenching constants (kq) according to the equation KSV = τ0kq. KSV of Gd-HMME phosphorescence is larger than that of Gd-TPP. The larger kq of Gd-HMME stems from a better energy overlap between its T1 and the second excited state of oxygen, as demonstrated by its higher singlet oxygen quantum yield. Thus, the difference between the kq values of metalloporphyrins is another factor contributing to their diverse oxygen responses.
研究领域:
生物医学
·
光化学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2015
·Vol. 39
·期 9
·7363-7371
·
IF 3.086
Wen-Yong Hu,Huan Liu,Yuan-Zhi Shao
In this study, four bi-modal core-shelled contrast agents of SiO2(FITC)@Gd2O(CO3)2·H2O with varying shell thicknesses but the same cores have been prepared via a two-step wet chemistry method. The four samples were quite close to sphericity and their averaged diameters were 127, 140, 148.7 and 174.0 nm. The composition of their shells was also examined. As the shell thickness increased, the fluorescence intensity halved but the longitudinal relaxivity remained high (28, 29, 27, 24 mM−1 s−1). The measured relaxivities of the samples were more than 5.8 times higher than the relaxivity of Gd-DTPA-BMA in a 0.55 T MR (magnetic resonance) system. The levels of cytotoxicity were tested on four cell lines (293, HeLa, HFL1, MCF-7) and the results indicated that the samples were safe. The intracellular fluorescence in HeLa cells was clearly observed using laser confocal microscopy. These results showed that this material had potential for application in MR-fluorescence bi-modal imaging.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Physical Chemistry C
·
2014
·
IF 4.835
Bing Chen,Xvsheng Qiao,Dengfeng Peng,Xianping Fan
In this study, hexagonal-phase NaY0.6–xCe0.1Gd0.3EuxF4 nanorods were synthesized via a mild solvothermal method. By modifying the Eu3+ dopant concentration, the crystal phase, morphology, and luminescent properties were well controlled. A broad excitation band centered at around 260 nm corresponding to the 2F5/2 → 4f-5d transition of Ce3+ was detected in the hosts containing Gd3+ ions by monitoring the Eu3+ emissions, indicating that an efficient Ce3+ → Eu3+ energy transfer occurred via the Gd3+ sublattice. Luminescence decay behaviors of the NaY0.6–xCe0.1Gd0.3EuxF4 nanorods were studied, and the energy transfer mechanism was discussed. An obvious rising edge on the luminescence decay curve of Eu3+ ions in the NaY0.6–xCe0.1Gd0.3EuxF4 nanorods was observed. The rising time is proposed to describe the energy migration time from Ce3+ to Eu3+ via the Gd3+ sublattice.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
BIOMATERIALS
·
2018
·
IF 8.806
Zhe Yang,Wenshan He,Hongyi Zheng,Jielin Wei,Pei Liu,Wei Zhu,Leping Lin,Li Zhang,Changfeng Yi,Zushun Xu,Jinghua Ren
Theranostic agents with perfect properties are needed urgently for the development of imaging guided photothermal therapy (PTT). In this work, Gd-integrated polypyrrole nanotheranostic agent (PPy@BSA-Gd) was successfully built through selecting bovine serum albumin (BSA) as both stabilizers for polymerization and biomimetic mineralization in "one pot". The obtained PPy@BSA-Gd possessed high stability and excellent photothermal property. Besides, relevant cellular assays indicated that PPy@BSA-Gd had fantastic cytocompatibility which could be further internalized by cancer cells. Due to their high longitudinal relaxivity value (r 1 = 10.203 mM −1 s −1 ), PPy@BSA-Gd could serve as considerable probe for T 1 -weighted magnetic resonance imaging (MRI). After tail vein injection of PPy@BSA-Gd, the MR signal of tumor section exhibited a time-dependent increase, indicating effective tumor accumulation of PPy@BSA-Gd. Notably, when exposed to 808 nm laser, the tumor growth of PPy@BSA-Gd treated mice could be inhibited by photothermal ablation successfully. All the results demonstrated the well-designed PPy@BSA-Gd have the potential for tumor diagnose and photothermal therapy.
研究领域:
生物医学工程
·
纳米医学
·
影像医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2021
·
IF 9.028
Ying Xiong,Yumei Zhao,Xingkun Qi,Jiayi Qi,Yuanyuan Cui,Haibiao Yu,Ying Cao
In this paper, Gd-promoted Co3O4 catalysts were prepared via a facile coprecipitation method for low-temperature catalytic N2O decomposition. Due to the addition of Gd, the crystallite size of Co3O4 in the Gd0.06Co catalyst surprisingly decreased to 4.9 nm, which is much smaller than most additive-modified Co3O4 catalysts. This huge change in the catalyst’s textural structure endows the Gd0.06Co catalyst with a large specific surface area, plentiful active sites, and a weak Co–O bond. Hence, Gd0.06Co exhibited superior activity for catalyzing 2000 ppmv N2O decomposition, and the temperature for the complete catalytic elimination of N2O was as low as 350 °C. Meanwhile, compared with pure Co3O4, Ea decreased from 77.4 to 46.8 kJ·mol–1 and TOF of the reaction increased from 1.16 × 10–3 s–1 to 5.13 × 10–3 s–1 at 300 °C. Moreover, Gd0.06Co displayed a quite stable catalytic performance in the presence of 100 ppmv NO, 5 vol % O2, and 2 vol % H2O.
研究领域:
催化化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2018
·
IF 3.794
Biao Lu,Yingbang Yao,Xiaodong Jian,Tao Tao,Bo Liang,Q.M. Zhang,Sheng-Guo Lu
The electrocaloric effect (ECE) in gadolinium and tin ions doped lead lanthanum zirconate titanate ceramics was investigated. Five samples with different compositions and hence different relaxor behaviors and polarization properties were prepared via a conventional solid-state reaction process. The ECE was measured directly by a high resolution thermometer from 293 K to 423 K. The results show that the ECE is mainly determined by the number of polarization states and polar-correlation strength . Furthermore, the results reveal that the temperature variation of ECE around Curie temperature is associated with the generation rate, activation energy , size and freezing temperature of polar nanoregions. As a result, Sn doped PLZT composition exhibits the best ECE, i.e. , a peak ΔT > 2 K obtained at 5 MV/m, and ΔT > 1.78 K achieved in the whole temperature range measured at the same field, which are very attractive for high performance ECE devices.
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
Journal of Materiomics
·
2021
·
IF 6.425
Jing Chen,Nan Su,Xiao Li Zhu,Xiao Qiang Liu,Jin-Xing Zhang,Xiang Ming Chen
BiFeO 3 has been recognized as one of the most important room-temperature single-phase multiferroic materials, but it still suffers from several drawbacks especially the weak magnetoelectric coupling. In the present work, the electric-field-controlled magnetism is achieved in Bi 1-x Gd x FeO 3 system, which involves a field-induced transition of Pna 2 1 / R 3 c at the morphotropic phase boundary region, and the magnetic state is switched between cycloidal state and canted antiferromagnetic state. The electric-field-controlled magnetism becomes reversible with the help of annealing, which is confirmed by magnetic hysteresis loops and the quantitative ratio of the involved phases for the as-sintered, as-poled and as-annealed samples. Compared with the systems of Bi 1-x Nd x FeO 3 and Bi 1-x Sm x FeO 3 , it is easier to tune the symmetry from R 3 c to Pna 2 1 with lower rare earth-content, and the field-induced transition is more apparent and subsequently leads to more significant electric-field-controlled magnetism in a wider composition range.
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）