DENTOMAXILLOFACIAL RADIOLOGY
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2021
·Vol. 50
·期 7
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IF 2.419
Hu ZiYang,Wang TieMei,Pan Xiao,Cao DanTong,Liang JiaHao,Gao AnTian,Xie Xin,Xu Shi,Miao LeiYing,Lin ZiTong
Objectives:To evaluate the diagnostic accuracy using sodium iodide (NaI) and dimethyl sulfoxide (DMSO) as contrast agent in cone beam computed tomography (CBCT) scanning, and compare this with micro-CT.Methods:18 teeth were cracked artificially by soaking them cyclically in liquid nitrogen and hot water. After pre-treatment with artificial saliva, the teeth were scanned in four modes: CBCT routine scanning without contrast agent (RS); CBCT with meglumine diatrizoate (MD) as contrast agent (ES1); CBCT with NaI + DMSO as contrast agent (ES2); and micro-CT (mCT). The number of crack lines was evaluated in all four modes. Depth of crack lines and number of cracks presented from the occlusal surface to the pulp cavity (Np) in ES2 and micro-CT images were evaluated.Results:There were 63 crack lines in all 18 teeth. 45 crack lines were visible on ES2 images as against four on the RS and ES1 images (p<0.05) and 37 on micro-CT images (p>0.05). Further, 34 crack lines could be observed on both ES2 and micro-CT images, and the average depth presented on ES2 images was 4.56 ± 0.88 mm and 3.89 ± 1.08 mm on micro-CT images (p<0.05). More crack lines could be detected from the occlusal surface to the pulp cavity on ES2 images than on micro-CT images (22 vs 11).Conclusion:CBCT with NaI +DMSO as the contrast agent was equivalent to micro-CT for number of crack lines and better for depth of crack lines. NaI + DMSO could be a potential CBCT contrast agent to improve diagnostic accuracy for cracked tooth.
研究领域:
口腔医学
·
影像学
✓ 已验证
DOI
高影响因子
Journal of the Mechanical Behavior of Biomedical Materials
·
2022
·
IF 4.042
Ziyang Hu,Xiao Pan,Yanni Hu,Shi Xu,Antian Gao,Dantong Cao,Zitong Lin
Objectives To explore the feasibility of using sodium iodide (NaI)+dimethyl sulfoxide (DMSO)+ethyl alcohol+ethyl acetate as a cone-beam CT (CBCT) contrast agent in the diagnosis of vertical root fracture (VRF). Methods 21 endodontically treated VRF teeth of 21 patients were collected in this study. All these 21 teeth were confirmed subtle fracture lines under transillumination, the number and position of fracture lines were recorded. All these patients had CBCT routine scanning (RS1) before extraction. After extraction, the teeth was performed micro-CT scanning and 3 in vitro CBCT scanning: CBCT routine scanning in vitro (RS2), CBCT enhanced scanning using meglumine diatrizoate (MD) as contrast agent(ES1); and CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent(ES2). The number of fracture lines was evaluated on all the 5 scanning modes and the accuracy of diagnosis was calculated. Results In all, there were 43 fracture lines on the 21 teeth. The accuracy of detection of fracture lines of CBCT RS1, RS2, ES1, ES2 and micro-CT was 0%, 20.9% (9/43), 11.6% (5/43), 93% (40/43) and 95.3% (41/43) respectively. Significant differences were found between ES2 vs. RS2, ES2 vs. ES1 ( p < 0.01); however, no significant difference was found between ES2 vs. micro-CT ( p > 0.05). Conclusion CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent could be a prospective technique in the diagnosis of VRF.
研究领域:
牙医学
·
影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Heliyon
·
2024
·
IF 3.4
Ziyang Hu,Yanni Hu,Shi Xu,Jia Zhuang,Dantong Cao,Antian Gao,Xin Xie,Zitong Lin
Objectives This study aims to investigate the use of sodium iodide (NaI), dimethyl sulfoxide (DMSO), ethyl alcohol, and ethyl acetate as cone-beam CT (CBCT) contrast agents for diagnosing cracked teeth. The optimal delay time for detecting the number of crack lines beyond the dentino-enamel junction (Nd), the number of cracks extending from the occlusal surface to the pulp cavity (Np), and the depth of the crack lines was explored. Methods 14 human extracted cracked teeth were collected, 12 were used for enhanced scanning, and 2 were used for exploring the characteristic of crack lines. The teeth were scanned in 3 CBCT enhanced scanning (ES) modes: ES1 using meglumine diatrizoate (MD); ES2 using NaI and DMSO, ES3 using NaI, DMSO, ethyl alcohol and ethyl acetate. Three delay times (15mins, 30mins, and 60mins) were set for scanning. Nd, Np, and depth of crack lines were evaluated. Results There were totally 24 crack lines on 12 cracked teeth. Nd was 10 in ES1 at 60mins, 24 in ES2 at 60mins and 24 in ES3 at 15mins. Np was 1 in ES1 at 60mins, 10 in ES2 at 60mins and 21 in ES3 at 60mins, and there were significantly different among them ( p < 0.01). The average depth presented on ES3 was significantly deeper than ES1 and ES2 ( p < 0.01). Conclusion NaI, DMSO, ethyl alcohol and ethyl acetate show potential as contrast agents for enhanced CBCT scanning in diagnosis of cracked teeth and their depth in vivo . A delay time of 15 min is necessary to confirm the existence of crack lines, while a longer delay time is required to ascertain if these crack lines extend to the pulp cavity.
研究领域:
牙医学
·
影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Bin Jiang,Kai Cheng,Na Zhang,Na Yang,Luhong Zhang,Yongli Sun
Herein, hydrophobic PVDF membranes were facilely transformed into highly hydrophilic and underwater superoleophobic ones via one-step dip-coating in tannic acid (TA)/sodium periodate (NaIO 4 )-mixed solution. The employment of NaIO 4 could not only facilitate TA oxidation and deposition, but also introduce abundant hydrophilic carboxyl groups on membrane surface. Consequently, compared with the pristine PVDF membrane, the modified membrane showed much higher hydrophilicity and underwater oleophobicity with water contact angle decreasing from 121° to 32°, oil contact angle increasing from 116° to 162° and a tilt angle of just 2°. In contrast to the two-step modification (deposition of TA followed by post-oxidation by NaIO 4 ), our approach endowed the membrane with dramatically improved permeability (>2400 LMH/bar) and oil rejection (>98%) when dealing with different types of oil-in-water emulsions. Additionally, the membrane displayed excellent antifouling performance with flux recovery ratios of above 95% and favorable reusability after 5-cycle filtration tests. Moreover, the membrane possessed a stable TA coating even being subjected to harsh pH solutions or sonication. This work provides a simple, robust and cost-effective strategy for membrane modification.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
Journal of Cleaner Production
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2020
·
IF 7.246
Li Ping Liao,Yan Qing Yao,Gang Wang,Cun Yun Xu,De Bei Liu,Guang Dong Zhou,Yuan Xin Zhong,Qun Liang Song
Hot carriers in hybrid perovskite have been proven to have eminent properties with long carrier cooling time and long carrier migration distance. The invention of the internally photoemitted hot carrier (IPHC) solar cell recently makes it possible to utilize the hot electrons in CH 3 NH 3 PbI 3 perovskite and capture their excess energies under steady state illumination. How to further improve the efficiency of IPHC cells is challenging and crucial to demonstrate their effectiveness. In this work, sodium iodide (NaI) is added into the CH 3 NH 3 PbI 3 precursor solution for inducing a P-type doping and downshifting its Fermi level. The lowered energy barrier at the interface of Au/doped CH 3 NH 3 PbI 3 promotes the hot electron extraction, thereby enhancing the power conversion efficiency of IPHC devices. The FTO/TiO 2 /Au/Na + -doped MAPbI 3 construction with considerable photocurrent would be an alternative approach for light-to-electricity conversion.
研究领域:
材料科学
·
能源技术
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Qinggele Borjihan,Xuefang Liang,Ting Chen,Douxin Xiao,Yanling Zhang,Haixia Wu,Qing Zhang,Alideertu Dong
ABSTRACT The growing incidence of thyroid disease triggered by excess iodine uptake poses a severe health threat throughout the world. Extracellular interference therapies impede iodine transport across the sodium-iodide symporter (NIS) membrane protein and thus prevent excessive iodine uptake by thyroid cells, which may lessen the occurrence of disease. Herein, we for the first time utilized nano-starch particles (St NPs) to regulate iodine transport across the NIS protein of thyroid cells by using extracellular interference therapy. By precisely encapsulating iodine within the cavity of a glucan α-helix via hydrogen bonding, extracellular St NPs prevented excess iodine uptake by thyroid cells in vitro and in vivo ; this down-regulated the expression of NIS protein (0.06-fold) and autophagy protein LC3B-II (0.35-fold). We also found that St NPs regulated the metabolic pathway of iodine in zebrafish. We believe this proposed strategy offers a novel insight into controlling iodine uptake by the thyroid and indicates a new direction for preventing iodine-induced thyroid disease.
研究领域:
内分泌学
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纳米技术
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治疗学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Chao Hu,Yeqing Xu,Mingmin Wang,Shixuan Cui,Hangjun Zhang,Liping Lu
Bisphenol analogues are widely used in industrial and daily-use consumer products having imperfect thyroid hormones (THs) structures. Widespread exposure interferes with thyroid-related health outcomes in human. The mechanisms of disruption on TH synthesis and subsequent thyroid dysfunction by different bisphenol analogues remain unclear. Here, we evaluated bisphenol-induced thyroid endocrine disruption in C57BL/6 mice at doses of 0.002, 0.02, 2, and 20 mg/kg body weight/day (BW/d) for five consecutive weeks. Administration of 20 mg/kg BW/d bisphenol S (BPS) and 2 mg/kg BW/d tetrabromobisphenol S (TBBPS) significantly increased serum thyrotropin (TSH) levels to 1.21-fold and 1.20-fold of control group, respectively, indicating that bisphenols induced thyroid dysfunction in mice. Height of the thyroid follicle epithelium significantly increased to 1.27-, 1.24-, 1.26-, and 1.36-fold compared to control group with BPA, BPS, TBBPA, and TBBPS at 20 mg/kg BW/d, respectively, indicating impairment of the thyroid gland structure, and TBBPS showed potent effect. Exposure to bisphenol analogues of 0.02 mg/kg BW/d downregulated the protein expression levels of thyrotropin receptor, the sodium/iodide symporter, thyroperoxidase. The TH-dependent effects were further determined using the T-Screen assay at 10 −11 M to 10 −5 M concentrations. Bisphenol analogues significantly decreased TH-dependent GH3 cell proliferation, indicating the antagonistic activity of bisphenol analogues. The gene responsible for THs synthesis of thyrotropin releasing hormone receptor and TSH were upregulated, but downregulation of thyroid receptor β was observed. Our results suggest that bisphenol analogues distinctly induce thyroid dysfunction via TH synthesis, implying adverse effect of bisphenol analogues on TH homeostasis and subsequent physiological processes.
研究领域:
内分泌学
·
毒理学
·
环境健康
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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