RSC Advances
·
2014
·Vol. 4
·期 93
·51696-51702
·
IF 3.708
Jingwen Zhao,Shichao Jiang,Reila Zheng,Xin Zhao,Xinliang Chen,Cunyi Fan,Wenguo Cui
A smart and stable electrospun fibrous drug carrier was fabricated to release an incorporated drug in response to the local presence of acid and to provide a favourable micro-environment for tissue regeneration. To fabricate the electrospun fibrous scaffolds responsive to the local pH variation, sodium bicarbonate, a component of acid response, was facilely incorporated into drug-loaded electrospun fibers by co-electrospinning. The analysis of X-ray photoelectron spectroscopy, Fourier-transform infrared spectrometry, X-ray diffraction, Differential scanning calorimetry and water contact angles demonstrated that the sodium bicarbonate was successfully incorporated into the electrospun fibers. The in vitro drug release results showed that the release rate of an anti-cancer drug 5-fluorouracil in an acidic environment from the electrospun fibrous scaffolds was proportional to the concentration of sodium bicarbonate, and the structure of the electrospun fibrous scaffolds was well maintained before and after the drug release. The acid-responsive release of 5-fluorouracil for a short time was found to effectively inhibit osteosarcoma cell growth, and the electrospun fibrous scaffolds with long-term stability supported fibroblast adhesion and proliferation, indicating the potential for subsequent tissue regeneration.
研究领域:
生物材料学
·
肿瘤学
·
药剂学
✓ 已验证
DOI
高影响因子
CHEMICAL PAPERS
·
2023
·
IF 2.2
Zhang Lie-yuan,Liu Jie-guang,Han Ying,Zhang Shu-min,Jiang Long-fa,Zhan Chun-rui,Zeng Chen-hui,Wang Wen-jun
An automatic potentiometric setting dynamic pH titration method for the determination of sodium bicarbonate in compositions of smoke-type fireworks was developed. After wetting the sample with 0.1 mL ethanol, added 60 mL of deionized water for dissolution, ultrasound for 10 min, filtered and removed the insoluble matter, and then used a potentiometric titrator to drop 0.1 mol/L of hydrochloric acid. The experimental results showed that the limit of quantitation was 0.1%, the recoveries were 96.1–104.8% and the relative standard deviation was 0.56–3.11% when the sample weigh 0.2 g. The automatic potentiometric setting dynamic pH titration method is simple to operate and can accurately and quickly determine the content of sodium bicarbonate in compositions of smoke-type fireworks.
研究领域:
化学分析
·
烟花爆竹安全
✓ 已验证
产品关联
DOI
高影响因子
BIORESOURCE TECHNOLOGY
·
2024
·
IF 9.7
Wenlong Wu,Jinwei Zhang,Weijie Zhu,Shouhui Zhao,Yuchen Gao,Yan Li,Lei Ding,Heng Ding
A novel porous manganese and nitrogen co-doped biochar (Mn-N@SBC) was synthesized via one-step pyrolysis, utilizing loofah agricultural waste as the precursor and NaHCO 3 as the activator. The behavior of bisphenol A adsorbed on Mn-N@SBC was evaluated using static batch adsorption experiments. Compared to direct manganese-nitrogen co-doping, co-doping based on NaHCO 3 activation significantly increased the specific surface area (231 to 1027 m 2 ·g −1 ) and adsorption capacity (15 to 351 mg·g −1 ). Wide pH (2–10) and good resistance to cation/anion, humic acid and actual water demonstrated the robust adaptability of Mn-N@SBC to environmental factors. The significantly reduced specific surface area after adsorption, adverse effects of ethanol and phenanthrene on the removal of bisphenol A, and theoretically predicted interaction sites indicated the primary adsorption mechanisms involved pore filling, hydrophobicity, and π-π-electron-donor–acceptor interaction. This work presented an approach to create high-efficiency adsorbents from agricultural waste, offering theoretical and practical guidance for the removal of pollutants.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Energy Materials
·
2022
·
IF 6.959
Huichao Liu,Wanhui Shi,Hua Song,Yunzhen Chang,Liping Feng,Wenjing Hou,Yanping Li,Yun Zhao,Sheng Zhu,Gaoyi Han
Hierarchically porous carbons (HPCs) have attracted much attention because of their potential application in carbon-based supercapacitors. Here, we list a facile and green method to obtain HPCs by annealing a coal tar pitch with sodium bicarbonate. The produced gases and sodium carbonate template can guide the formation of carbon products with a multiscale pore structure. Further activation by KOH endows HPC with a surface area of 2851.7 m2 g–1 and a total pore volume of 2.4 cm3 g–1. Accordingly, such an HPC electrode achieves a specific capacitance of 321.5 F g–1 (0.5 A g–1) and retains 230.0 F g–1 (100.0 A g–1). Moreover, the HPC-based symmetric supercapacitor exhibits superior cyclic stability (1.1% capacity decay after 30,000 cycles) in an aqueous electrolyte. In the TEABF4/acetonitrile electrolyte, the assembled device displays a high energy density of 53.0 Wh kg–1 and still retains 77.9% even when the power density is increased from 750.0 to 15,000.0 W kg–1. We believe that the salt-assisted synthesis strategy for HPC paves a green way to developing high-performance supercapacitors.
研究领域:
材料科学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）