Novel, portable, probe-free, liquid cellulose biosensor was explored via a facile one-pot process for Cu 2+ ions detection by naked eyes. The as-prepared biosensor displayed specific recognition towards Cu 2+ ions in aqueous solution, even in complex urine and serum samples within 10 s, showing fast response characteristic. There is barely any interference on the Cu 2+ ions detection by other metal ions or other complex substances in urine and serum, and the corresponding detection limit is as low as 1.185, 1.9309 and 1.9154 ppm, respectively. Moreover, the cellulose biosensor could act as an excellent candidate to sense Cu 2+ ions in biological samples including urine and serum from SD rats with satisfying accuracies and biocompatibility. This study exploits a potential application of cellulose in biosensing and monitoring related to Cu 2+ ions.
Fluorescent sensor has demonstrated to be a facile and effective method to detect heavy metal ions owing to its unique characteristics such as simplicity, ease of operation and cost-effectiveness. In this work, a novel fluorescent probe with aggregation-induced emission (AIE) feature that contains an amide ligand base on the tetraphenylethylene (TPE) dye was designed and successfully synthesized. The utilization of the AIE-active fluorescent probe (named as FDPA) for detection of Cu 2+ in aqueous solution has also been examined. We demonstrated that the resultant AIE-active molecule displays amphiphilic property and can self-assemble in aqueous solution with remarkable enhancement of fluorescent intensity owing to its AIE feature. The detection limit of probe for Cu 2+ determination is 6.11 × 10 −9 M and shows excellent selectivity in the presence of competitive ions. This work provides a useful route to overcome the fluorescence quenching of conventional fluorescent probes in aqueous solution and an elegant way to prepare fluorescent probes with better fluorescence properties.
危险品化学品经营许可证（带存储）