Lignin is the largest renewable source of aromatic building blocks in nature and has great potential as a starting material for the production of bulk or functionalized aromatic compounds, providing a suitable alternative to widely used petroleum-derived chemicals. In this work, we present a novel 1,4-cyclohexanediol (CHDO) preparation from lignocellulose. In contrast to conventional methods, this pathway has taken the lignin-degrading monomers as a starting point, and flexibly employs a series of oxidative and catalytic reactions to achieve the preparation of CHDO. The proposed pathway consists of a two-step chemical process to efficiently obtain high yields of CHDO from lignocellulose. The first step is the oxidation of lignin-derived monophenols to p -hydroxyl phenolic compounds using the Dakin oxidation reaction (yield>80%), and finally the de-functionalization and hydrogenation of the resulting monomers using the hydrodeoxygenation (HDO) reaction.
Funneling complex lignocellulose into simple and valuable building blocks has garnered significant interest in the field of biorefinery as a competitor to the petrochemical industry. Reductive Catalytic Fractionation (RCF) of lignocellulose, an innovative biorefinery technology, provides a promising strategy for complete valorization of lignocellulose into various valuable chemicals. In this study, integrated processes utilizing RCF strategies were developed to achieve complete conversion of lignocellulose into various simple and valuable platform chemicals. The core of this system is the flexible use of commercial Ni catalysts including Raney Ni and Ni/SiO 2 -Al 2 O 3 which brings great benefits for future upscale and industrial applications. Surprisingly, both monomers derived from lignin and high molecular weight fractions could be converted to 4-ethylcyclohexanol while carbohydrate pulp was converted to furfural and 5-methoxymethylfurfural (MMF) in one-pot. MMF could be further upgraded to 2,5-Furandicarboxylicacid (FDCA) via catalytic oxidation by Ru/C catalysts. This work could inspire the development of more sustainable and economically viable biorefinery processes.
危险品化学品经营许可证（带存储）