Journal of the Mechanical Behavior of Biomedical Materials
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2022
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IF 4.042
Ziyang Hu,Xiao Pan,Yanni Hu,Shi Xu,Antian Gao,Dantong Cao,Zitong Lin
Objectives To explore the feasibility of using sodium iodide (NaI)+dimethyl sulfoxide (DMSO)+ethyl alcohol+ethyl acetate as a cone-beam CT (CBCT) contrast agent in the diagnosis of vertical root fracture (VRF). Methods 21 endodontically treated VRF teeth of 21 patients were collected in this study. All these 21 teeth were confirmed subtle fracture lines under transillumination, the number and position of fracture lines were recorded. All these patients had CBCT routine scanning (RS1) before extraction. After extraction, the teeth was performed micro-CT scanning and 3 in vitro CBCT scanning: CBCT routine scanning in vitro (RS2), CBCT enhanced scanning using meglumine diatrizoate (MD) as contrast agent(ES1); and CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent(ES2). The number of fracture lines was evaluated on all the 5 scanning modes and the accuracy of diagnosis was calculated. Results In all, there were 43 fracture lines on the 21 teeth. The accuracy of detection of fracture lines of CBCT RS1, RS2, ES1, ES2 and micro-CT was 0%, 20.9% (9/43), 11.6% (5/43), 93% (40/43) and 95.3% (41/43) respectively. Significant differences were found between ES2 vs. RS2, ES2 vs. ES1 ( p < 0.01); however, no significant difference was found between ES2 vs. micro-CT ( p > 0.05). Conclusion CBCT enhanced scanning using NaI+DMSO+ethyl alcohol+ethyl acetate as contrast agent could be a prospective technique in the diagnosis of VRF.
研究领域:
牙医学
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影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Laser & Photonics Reviews
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2023
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IF 11
Peng Ran,Xinya Chen,Zeng Chen,Yirong Su,Juan Hui,Lurong Yang,Tianyu Liu,Xiangyang Tang,Haiming Zhu,Xiao-Jian She,Yang (Michael) Yang
Copper-based halides have emerged as promising scintillator materials for X-ray imaging due to their favorable photophysical characteristics, such as negligible self-absorption, high light output, and fast decay. Among these materials, Cs 3 Cu 2 I 5 , a blue emitter, currently delivers the highest scintillation light output under steady-state X-rays. However, there is a significant spectral mismatch between its emission band and the spectral responsivity of regular flat-panel photodiode arrays. In this study, a comprehensive analysis of the physical properties of the CsCu 2 I 3 scintillator is conducted, and its perfect spectral compatibility is discovered, which results in a higher photodiode signal despite its relatively lower light output compared to typical Cs 3 Cu 2 I 5 scintillators. Furthermore, CsCu 2 I 3 exhibits faster light decay properties, making it especially suitable for Computed Tomography (CT) X-ray imaging. High-quality X-ray cone beam computed tomography (CBCT) imaging is successfully demonstrated using the fast-decaying CsCu 2 I 3 scintillator screen. Additionally, the flexibility of the scintillator allows for non-planar imaging, showcasing advantages not available with traditional rigid scintillators. These results not only highlight the significant promise of the CsCu 2 I 3 scintillator but also emphasize the necessity of considering spectral compatibility when designing novel scintillator materials.
研究领域:
医学影像学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Heliyon
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2024
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IF 3.4
Ziyang Hu,Yanni Hu,Shi Xu,Jia Zhuang,Dantong Cao,Antian Gao,Xin Xie,Zitong Lin
Objectives This study aims to investigate the use of sodium iodide (NaI), dimethyl sulfoxide (DMSO), ethyl alcohol, and ethyl acetate as cone-beam CT (CBCT) contrast agents for diagnosing cracked teeth. The optimal delay time for detecting the number of crack lines beyond the dentino-enamel junction (Nd), the number of cracks extending from the occlusal surface to the pulp cavity (Np), and the depth of the crack lines was explored. Methods 14 human extracted cracked teeth were collected, 12 were used for enhanced scanning, and 2 were used for exploring the characteristic of crack lines. The teeth were scanned in 3 CBCT enhanced scanning (ES) modes: ES1 using meglumine diatrizoate (MD); ES2 using NaI and DMSO, ES3 using NaI, DMSO, ethyl alcohol and ethyl acetate. Three delay times (15mins, 30mins, and 60mins) were set for scanning. Nd, Np, and depth of crack lines were evaluated. Results There were totally 24 crack lines on 12 cracked teeth. Nd was 10 in ES1 at 60mins, 24 in ES2 at 60mins and 24 in ES3 at 15mins. Np was 1 in ES1 at 60mins, 10 in ES2 at 60mins and 21 in ES3 at 60mins, and there were significantly different among them ( p < 0.01). The average depth presented on ES3 was significantly deeper than ES1 and ES2 ( p < 0.01). Conclusion NaI, DMSO, ethyl alcohol and ethyl acetate show potential as contrast agents for enhanced CBCT scanning in diagnosis of cracked teeth and their depth in vivo . A delay time of 15 min is necessary to confirm the existence of crack lines, while a longer delay time is required to ascertain if these crack lines extend to the pulp cavity.
研究领域:
牙医学
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影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）