ANALYTICAL LETTERS
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2024
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IF 1.6
Jing Yang,Zhe Lv,Bo Yang,Xiangdong Guo,Feiyong Qu,Yanping Miao,Dehui Li,Hongmei Gao,Wei Li
Photoluminescence enhancement provides an effective way to improve the performance of quantum dots. In this study, lead(II) determination was demonstrated based on phosphorescence enhancement using 1-thioglycerol-capped Mn-doped ZnS quantum dots. Under the optimized conditions, good linear correlations were obtained for Pb2+ from 10.00 to 5000 nM and 0.05000 to 100.0 mM with correlation coefficients of 0.9997 and 0.9979 and a detection limit of 2.56 nM. The method demonstrates good linearity and selectivity, suitable sensitivity, easy operation, and the determination of Pb2+ in Chinese herbal medicine.
研究领域:
分析化学
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环境科学
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DOI
高影响因子
ANALYTICAL CHEMISTRY
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2014
·
IF 5.825
Li-Jia Sang,He-Fang Wang
Discrimination of glycoproteins with different glycans is a significant but difficult issue. We presented here a new strategy for strengthening the discrimination of glycoproteins by introducing a new signaling channel, fluorescence polarization (FP), into a “single probe with three signaling channels” sensor array. The single probe was aminophenylboronic-acid-conjugated poly(acrylic acid)–Mn-doped ZnS quantum dots, and the three signaling channels were FP, room temperature phosphorescence and light scattering. Ten glycoproteins, including ovalbumin, fibrinogen, transferrin, horseradish peroxidase, vascular endothelial growth factor, immunoglobulin G, avidin, hyaluronidase, cellulase R-10, and glucose oxidase, were involved for evaluating the discriminating capability. The introduction of the FP signaling channel improved the discriminating power of the sensor array, so that the 10 glycoproteins at 0.15 μM could be well discriminated both in PBS buffer and in the presence of human serum sample. The identification accuracy of the unknown samples was 96.25% (77 out of 80) at the 0.15 μM level and 97.50% (78 out of 80) at the 0.2 μM level. The integration of the signaling patterns with different responsive principles was demonstrated as the promising way to enhance the discrimination power of the single-probe-based sensor arrays.
研究领域:
生物化学
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分析化学
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DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2018
·
IF 2.891
Tingting Gan,Nanjing Zhao,Gaofang Yin,Jianguo Liu,Wenqing Liu
As a kind of serious concern environmental toxic pollutants, sulfide is widely used in various industrial processes, and generated from the process of biological metabolism. However, the sensitive, rapid and effective detection of sulfide still remains challenge. In this paper, a simple and rapid room-temperature phosphorescence (RTP) method for the detection of sulfide with a high selectivity and sensitivity was proposed by using mercaptopropionic acid (MPA)-capped Mn-doped ZnS quantum dots (QDs) and Pb 2+ as a sensing system. Highly water-soluble MPA-capped Mn-doped ZnS QDs with phosphorescence emission property were successfully synthesized by microwave-assisted hydrothermal synthesis method. We discovered that the as-prepared QDs displayed effectively phosphorescence quenching to Pb 2+ in pH 11.5 borax-NaOH buffer solution, then demonstrated remarkable phosphorescence recovery after the addition of sulfide to the QDs-Pb 2+ system. Therefore, based on the phosphorescence "off-on" behavior of MPA-capped Mn-doped ZnS QDs, a simple, sensitive and selective phosphorescence method for rapid detection of sulfide was successfully developed. The quenching and recovery of the phosphorescence of MPA-capped Mn-doped ZnS QDs have been studied in detail. Under the optimized conditions, the recovered degree of RTP intensity had a very good linear relationship with sulfide concentration in the range of 2 × 10 −7 –80 × 10 −7 mol L −1 with a correlation coefficient of 0.9982, and a lower detection limit of 6.89 × 10 −8 mol L −1 . The relative standard deviations for eleven times repeated detections of 5 × 10 −6 and 8 × 10 −6 mol L −1 sulfide were 3.24% and 4.50%, respectively. The proposed method could effectively avoid the interferences of common anions, fluorescence substances and scattering light. Furthermore, it was successfully applied to detect sulfide in real water samples with satisfactory results, and the recoveries were in the range from 94.2% to 107.1%. This work will provide the basis of method for the development of fast and on-line monitoring sensors of small molecule pollutions in water.
研究领域:
环境科学
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分析化学
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DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Wenjuan Dong,Zhuorong Fan,Ziyu Feng,Jia Shi,Xinyu Shi,Shengmei Song,Xiaojuan Gong,Wenting Liang
Phenolic compounds have increasingly serious damage to the environment, and it is imperative to develop new detection means for them. In this study, Mn-doped ZnS quantum dot (Mn/ZnS QDs) were synthesized and conjugated with horseradish peroxidase (HRP) via its ligand N-acetyl-L-cysteine (NAC) to form a bionanoconjugates with the phosphorescent response, named Mn/ZnS QDs-HRP. In the presence of a small amount of hydrogen peroxide, phenolic compounds can quench the phosphorescence of Mn/ZnS QDs-HRP, and the quenching type is speculated to be a synergistic effect of dynamic mechanism and internal filtration effect. Taking catechol as an experimental object, the phosphorescence signal of Mn/ZnS QDs-HRP showed a good linear correlation with the concentration of catechol, and the detection limit was 0.068 μM (S/N = 3). The strong anti-interference ability of room temperature phosphorescence endows the probe with excellent sensitivity, and the specific recognition performance of the enzyme makes it have excellent selectivity. Moreover, the probe exhibits good repeatability and stability. When used for actual sample detection, Mn/ZnS QDs-HRP provides stable and reliable quantification of catechol in different water samples with spiked recoveries of 92.3–104.4 %. This study provides a sensitive, convenient, and efficient phosphorescent response sensor for detecting phenolic compounds, which is of positive significance for environmental protection.
研究领域:
环境科学
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生物化学
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纳米技术
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DOI
高影响因子
FOOD CHEMISTRY
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2020
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IF 6.306
Xinyue Yuan,Dianwei Zhang,Xuecheng Zhu,Huilin Liu,Baoguo Sun
Manganese-doped zinc sulfide quantum dots (Mn-ZnS QDs) are promising candidates for multi-channel sensing analysis due to their multi-dimensional optical properties. In this study, we integrated amino-silane and ionic liquid co-modified Mn-ZnS QDs and covalent organic frameworks (COFs) into optosensing nanoparticles to provide triple-dimensional optical response signals and combined them with chemometrics for the analysis of multiple pesticide residues . Through the exploration and optimization of a series of conditions, fluorescence, room temperature phosphorescence, and ultraviolet−visible combined with chemometrics were used for the discrimination and recognition of multiple pesticide residues in fruits and vegetables. The ionic liquid of 1-vinyl-3-ethylimidazolium tetrafluoroborate was used to modify Mn-ZnS QDs to improve the optical response and enrichment of pesticide adsorption sites, which were also synergistically enhanced by the COF support. This is a potential method to discriminate pesticides efficiently and enables fast and reliable analysis of pesticides in the agricultural and food industries.
研究领域:
分析化学
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食品科学
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环境科学
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
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2011
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IF 5.874
Huan Yan,He-Fang Wang
Room-temperature phosphorescence (RTP) turn-on assay of heparin with tunable sensitivity and detection window was demonstrated on the basis of the target induced self-assembly of polyethyleneimine capped Mn-doped ZnS (PEI-Mn-ZnS) QDs. The proposed method can cover the whole therapeutic dosing concentration range in postoperation and long-term therapy (0.2–1.2 U/mL, 1.7–10 μM) and cardiovascular surgery (2–8 U/mL, 17–67 μM) in 10 mM Tris–HCl (pH 7.4) buffer and can be applied for heparin determination in 100-fold diluted human serum samples. The tunable sensitivity and detection window was ascribed to the tunable particle size and ligand loading amount of PEI-Mn-ZnS QD arising from the chain length (or molecule weight) and feed amount of PEI. The chain length of PEI exhibited significant effect on the particle size and ligand loading amount and ultimately had important influence on both the sensitivity and detection window. The feeding amount of PEI, however, greatly affected the ligand loading amount alone and, in turn, affected only the detection window.
研究领域:
生物化学
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分析化学
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医学检测
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DOI
PubMed
高影响因子
LUMINESCENCE
·
2013
·Vol. 29
·期 2
·151-157
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IF 1.273
Wei Bian,Jing Ma,Qiaoling Liu,Yanli Wei,Yingfu Li,Chuan Dong,Shaomin Shuang
N -acetyl- l -cysteine-capped Mn-doped ZnS quantum dots (QDs) were prepared by hydrothermal methods. It could emit phosphorescence at 583 nm with the excitation wavelength at 315 nm. The phosphorescence intensity of QDs could be quenched dramatically by increasing the concentration of Co 2+ ion. The novel phosphorescence sensor based on N -acetyl- l -cysteine-capped QDs was developed for detecting Co 2+ ion with a linear dynamic range of 1.25 × 10 –6 –3.25 × 10 –5 m . The limit of detection and RSD were 6.0 × 10 –8 m and 2.3%, respectively. Interference experiments showed excellent selectivity over numerous cations such as alkali, alkaline earth and transitional metal ions. The possible quenching mechanism was also examined by phosphorescence decays. The proposed phosphorescence method was further applied to the trace determination of Co 2+ ion in tap and pond water samples with recoveries of 97.75–103.32%. Copyright © 2013 John Wiley & Sons, Ltd.
研究领域:
分析化学
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材料科学
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环境科学
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DOI
PubMed
高影响因子
RSC Advances
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2016
·Vol. 6
·期 86
·83110-83116
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IF 3.289
Lijia Sang,Meiding Yang,Huipeng Zhou,Xinan Huang,Cong Yu
A bright white light emitting benzoperylene probe-polyethyleneimine capped quantum dot nanocomposite has been synthesized for the first time. The negatively charged benzoperylene probe with a carboxylic acid functional group tends to self-assemble in the presence of a polycation, and exhibits distinct induced excimer fluorescence. Phosphorescence emitting manganese doped zinc sulfide quantum dots (Mn-ZnS QDs) were capped with polyethyleneimine (PEI). The PEI capped Mn-ZnS QDs were used to induce the benzoperylene probe self-assembly. A bright white light emitting nanocomposite was obtained both in solution and in solid state. The white emission has Commission Internationale de l'Eclairage (CIE) coordinates of (0.33, 0.32), a color-rendering index (CRI) of 72.61 and correlated color temperature (CCT) of 5697 K. Multiple color emissions from blue to orange could also be obtained in a controllable manner via simple adjustment of the ratio of the PEI capped Mn-ZnS QDs and the benzoperylene probe. The nanocomposite displays good photo, chemical and long-term stability. A strong white light emitting LED device based on the nanocomposite was demonstrated.
研究领域:
材料科学
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光学
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2015
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IF 4.097
Qing Jin,Yan Li,Jianzhong Huo,Xiaojun Zhao
The phosphorescent 3-mercaptopropionic acid (MPA) capped Mn-doped ZnS quantum dots (MPA-Mn:ZnS QDs)-KMnO 4 hybrid system was developed to be an “off–on” phosphorescent switch based on chemical redox mechanism for detection of glutathione (GSH) in food, wine, and biological samples. By employing KMnO 4 as the quencher to the phosphorescence of MPA-Mn:ZnS QDs, GSH recovered the emission for its determination by the use of its reducibility. The possible mechanism for the restored phosphorescence was elucidated that SO 4 2− oxidized by KMnO 4 on the surface of the Mn:ZnS QDs was reduced to S 2− with the addition of GSH. The phosphorescent hybrid system allowed highly sensitive detection of GSH in aqueous solution with a detection limit of 97 nM and a wide linear range of 0.3–280 μM. The precision for 11 replicate detection of 200 μM GSH was 3.5% (relative standard deviation, RSD). The developed method was applied for the detection of GSH in food, wine, and biological samples with the quantitative spike recoveries from 95% to 104%.
研究领域:
分析化学
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生物分析
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DOI
高影响因子
RSC Advances
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2020
·Vol. 10
·期 30
·17906-17913
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IF 3.119
Xiaodong Lv,Peng Gao
Based on the optical quenching phenomenon, a smart mesoporous phosphorescent microsensor was built. It is a phenol microsensor, which inherits a high selectivity of molecularly imprinted polymers (MIPs) and room-temperature phosphorescence (RTP) properties of Mn-doped ZnS quantum dots (QDs). On the surface of silane-modified Mn-doped ZnS QDs, the phenol microsensor was synthesized by a sol–gel process. Because of the presence of a porogenic agent, a mesoporous structure played an important role in increasing the detection sensitivity. The MPTS-modified Mn-doped ZnS QDs were used as solid supports and auxiliary monomers. Under optimal conditions, the experiment for the detection of phenol had a linear range of 5.0 to 50 μmol L−1 with a correlation coefficient of 0.9983 and a high imprinting factor (IF) of 3.28. In addition, the as-prepared Mn-doped ZnS QD@ms-MIPs were successfully applied for phenol determination and selectivity in water samples. Therefore, this study provides a highly selective and sensitive mesoporous phosphorescent microsensor for the detection of phenol.
研究领域:
分析化学
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材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2014
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IF 2.291
Li-Na Wen,Meng-Xia Xie
s G-quadruplex DNA is an effective target for anticancer drug, and investigation of the G-quadruplex DNA with natural compounds plays a key role in the development of anticancer drugs. In this article, room temperature phosphorescence sensing system based on l -cysteine-capped Mn-doped ZnS QDs has been established. Sanguinarine can adsorb on the surface of Mn-doped QDs and quenched the phosphorescence emission of the sensor. When the G-quadruplex sequences combined with the sanguinarine of the QDs-sanguinarine system, the phosphorescence intensities of the QDs sensors would be restored, and the binding abilities of the G-quadruplex DNA with the sanguinarine can be evaluated by the phosphorescence recoveries of the sensor system. Based on the developed approach, the interaction of sanguinarine and six G-quadruplex DNA with various sequences (tel24-1, tel24-2, tel22, k-ras, HIF-1α and c-kit1) has been investigated. The results showed that the binding abilities of the G-quadruplex DNA with sanguinarine were related to their number of bases and conformations. The conformational changes of the six G-quadruplex DNA, after binding with sanguinarine, have also been probed by circular dichroism. Combining the changes of the phosphorescence lifetime, the binding mechanism of the G-quadruplex DNA and sanguinarine has been discussed. The developed method was simple, rapid and specific, and can avoid fluorescence interferences of the system, and it would be prospective to evaluate the interaction of the drug with different G-quadruplexes.
研究领域:
生物化学
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分析化学
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分子生物学
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癌症研究
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DOI
高影响因子
TALANTA
·
2013
·
IF 3.498
Wei Bian,Jing Ma,Wenrong Guo,Dongtao Lu,Meng Fan,Yanli Wei,Yingfu Li,Shaomin Shuang,Martin M.F. Choi
N -Acetyl-L-cysteine (NAC) and L-cysteine (Cys) capped Mn doped ZnS quantum dots (NAC-Mn/ZnS QDs and Cys-Mn/ZnS QDs) are firstly prepared by hydrothermal methods . These QDs display strong phosphorescence emission peaks at 583 and 580 nm upon excitation at 315 and 306 nm, respectively. Since their room-temperature phosphorescence is efficiently quenched by L-ascorbic acid (AA), they have been employed as phosphorescence probes for detecting AA. The linear working ranges are 2.5–37.5 and 2.5–47.5 µM and the limits of detection are 0.72 and 1.38 µM for NAC-Mn/ZnS QDs and Cys-Mn/ZnS QDs, respectively. The possible quenching mechanisms have been discussed in detail. The QDs probes are highly selective to AA over other common ions, amino acids , glucose and bovine serum album. Finally, they have been applied successfully for detection of AA in human urine samples with satisfactory results. The recoveries are 98–104%. Our work provides a simple and convenient phosphorescence method to determine AA in real samples.
研究领域:
分析化学
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生物医学
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产品关联
DOI
PubMed
高影响因子
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