ANALYTICA CHIMICA ACTA
·
2023
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IF 6.2
Kezhen Zhang,Xiaoyong Tian,Peipei Xu,Li Peng,Shanyi Guang,Jihong Feng,Hongyao Xu
Background Mg 2+ has long been recognized as one of the most vital cations due to its diverse physiological and pathological roles, making it indispensable in both biomedical and biological research. Organic fluorescent sensors are commonly employed for Mg 2+ detection, but they often lack high selectivity and exhibit poor hydrophilicity , limiting their biomedical applications. Results Herein, we introduced a novel organic-inorganic hybrid fluorescence sensor, PFHBS, constructed on the POSS nanoplatforms. The efficient connection between PEGylated POSS and the small molecule sensor FHBS through Click chemistry enhances the selectivity and reduces interference, making this chemical sensor ideal for the accurate detection of Mg 2+ . Furthermore, the incorporation of POSS amplifies the ligand field effect of FHBS, making it more conducive to Mg 2+ capture. The modification of PEG chains enhances the sensor's amphiphilicity, facilitating efficient cell penetration and effective Mg 2+ detection at the biological level. Significance Finally, relying on spontaneous permeation, coupled with its strong ligand field effect and excellent cell permeability , the chemosensor demonstrates the capability to intelligently remove excess Mg 2+ from the body. It has been successfully applied to mitigate renal overload resulting from acute Mg 2+ poisoning.
研究领域:
生物化学
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医学检测
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材料科学
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产品关联
DOI
PubMed
高影响因子
Advanced Healthcare Materials
·
2024
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IF 10
Weisin Chen,Hongwei Lu,Wenhao Yu,Lei Huang,Mengxuan Bian,Ning Wang,Xingdong Xiang,Guokang Mo,Cheng Zhang,Yulin Li,Libo Jiang,Jian Zhang
Autograft has long been the gold standard for various bone surgeries. Nevertheless, the increasing usage of synthetic implants is taking over the operation rooms due to biosafety and standardized protocols. To fulfill such tremendous needs, a magnesium-impregnated membrane is devised that steadily releases magnesium ions to stimulate osteogenesis. The compatibility of Magnesium oxide (MgO) particles is enhanced through hydration and grafting, characterized by scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). With detailed degradation profiles, an in-depth investigation of Magnesium transporter 1 (MagT1) for magnesium intake is carried out and engaging in the N-linked glycosylation by using RNAi and inhibitors. The glycosylation of secreted protein acidic and rich in cysteine (SPARC) affected extracellular secretion and mineral deposition, demonstrated by immunostaining and density-dependent color-SEM (DDC-SEM). Skull defects are treated by implanting magnesium-impregnated membranes in rats and evaluated them by micro-CT and histological exams. This study revealed the compatible integration of grafted magnesium hydroxide (g-MH) particles is the key to functional performance and critical to applicability in vivo; meanwhile, it opens the door to a biological rationale for designing biomimetic materials.
研究领域:
生物医学工程
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分子生物学
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2019
·Vol. 54
·期 20
·13247-13254
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IF 3.442
Liu Hao,Chen Bochao,Liao Libing,Fan Peng,Hai Yun,Wu Yuanyuan,Lv Guocheng,Mei Lefu,Hao Huiying,Xing Jie,Dong Jingjing
Metallic 1T MoS 2 greatly benefits the supercapacitance of MoS 2 due to its considerably higher conductivity as compared to semiconducting 2H MoS 2 . Alkali metals, such as Li, Na and K, are always used to prepare 1T MoS 2 through intercalation of alkali metal ions into the interlayer of 2H MoS 2 . Nevertheless, the influences of the alkali-earth metals as the guest in the interlayer of MoS 2 on its structure and electrochemical capacitor performance are rarely investigated. Herein, we introduced hydrated Mg ions as the guest into MoS 2 nanosheets. The interlayer spacing was increased to 1.144 nm after the introduction of hydrated Mg ions, larger than that of the pristine MoS 2 (0.620 nm) and restacking MoS 2 (0.626 nm). The enlarged interlayer spacing can accommodate more ions during intercalation process. Moreover, the 1T phase concentration after the introduction of hydrated Mg ions was as high as ~ 90%, which benefits the charge transfer during the charging/discharging processes. Consequently, the specific capacitance of the MoS 2 with Mg guest ions as well as the energy densities and power densities was greatly improved as compared to those of the restacking MoS 2 or pristine MoS 2 counterparts. The present work not only demonstrated a new strategy for engineering the physical properties and improving the electrochemical performance of MoS 2 supercapacitor electrode through pre-intercalation of alkali-earth metal ions in the interlayer of MoS 2 , but also has directive significance for the design of other layered electrode materials for energy storage systems.
研究领域:
材料科学
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电化学
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产品关联
DOI
高影响因子
ACS Nano
·
2022
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IF 18.027
Xiaoke Wang,Xixi Zhang,Gang Zhao,Hu Hong,Zijie Tang,Xijin Xu,Hongfei Li,Chunyi Zhi,Cuiping Han
Magnesium ion batteries have potential for large-scale energy storage. However, the high charge density of Mg2+ ions establishes a strong intercalation energy barrier in host materials, causing sluggish diffusion kinetics and structural degradation. Here, we report that the kinetic and dissolution issues connected to cathode materials can be resolved simultaneously using a tetraethylene glycol dimethyl ether (TEGDME)–water hybrid electrolyte. The lubricating and shielding effect of water solvent could boost the swift transport of Mg2+, contributing to a high diffusion coefficient within the sodium vanadate (NaV8O20·nH2O) cathode. Meanwhile, the organic TEGDME component can coordinate with water to diminish its activity, thus providing the hybrid electrolyte with a broad electrochemical window of 3.9 V. More importantly, the TEGDME preferentially amassed at the interface, leading to a robust cathode electrolyte interface layer that suppresses the dissolution of vanadium species. Consequently, the NaV8O20·nH2O cathode achieved a specific capacity of 351 mAh g–1 at 0.3 A g–1 and a long cycle life of 1000 cycles in this hybrid electrolyte. A mechanism study revealed the reversible interaction of Mg2+ during cycles. This organic water hybrid electrolyte is effective for overcoming the difficulty of multivalent ion storage.
研究领域:
储能
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电化学
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材料科学
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电池技术
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
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2025
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IF 6.9
Heng Yu,Wei Sun,Chenyang Zhang,Zechao Huangfu,Fuchao Fan
Due to the limitations of existing flotation technologies, the resource development of talc-containing molybdenum ores remains an urgent issue that must be addressed. The development of effective talc depressants has become a significant research focus. Studies indicate that the combination of sodium carboxymethyl starch (CMS) and magnesium ion (Mg 2+ ) can effectively inhibit talc, achieving high selective flotation of molybdenite. However, the interaction mechanism between CMS and Mg 2+ , as well as its depressing mechanism on the anisotropic surface of talc, remains unclear. To address this issue, this study employed multiple testing methods and combined micro-flotation tests to systematically compare the differences in adsorption and bonding mechanisms between the mixed dosing system and the sequential dosing system on various crystal surfaces of talc and molybdenite, while also exploring their impact on flotation behavior. The research results indicate that in the mixed dosing system, CMS and Mg 2+ interact with the surface of talc through complex formation, which enhances its hydrophilicity. When the concentration of CMS is 1 × 10 -3 mol/L, the average recovery rate of talc decreases to 14.82 %, while the recovery rate of molybdenite reaches 84.85 %, thereby facilitating the selective separation of talc and molybdenite.
研究领域:
矿物加工工程
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表面化学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2025
·
IF 19
Wei Yu,Xinru Zhang,Muge Gu,Yihui Zhang,Xiangqi Zhang,Jiayu Wang,Genjiang Zheng,Wei-En Yuan
Peripheral nerve injuries, often caused by trauma and tumor resection, severely impair motor and sensory functions. While autologous nerve grafting remains the gold standard, its efficiency is hindered by limited donor tissue availability, donor site morbidity, and neuropathic pain. Tissue-engineered nerve grafts, emerging as promising alternatives, still face challenges due to the lack of essential biochemical and biophysical cues for comprehensive nerve regeneration. This study introduces a Janus Mg 2+ /H 2 pump conduit, constructed with a MgH 2 @PLGA middle layer, polycaprolactone (PCL) outer layers, and a polydopamine-coated PCL (PCL@PDA) inner layer. The PCL provides structural support, while the MgH 2 @PLGA layer continuously releases Mg 2+ and H 2 as biochemical cues, driven by an acidic microenvironment and the MgH 2 -water reaction. PDA modification of the inner layer, serving as biophysical cues, further increases cell adhesion. Mg 2+ released from the conduit mitigates oxidative stress in Schwann cells and increases their expression of neurotrophic factors, while the H 2 attenuates inflammation, aiding nerve regeneration. In a rat sciatic nerve defect model, the conduit shows enhanced functional, electrophysiological, and histological recovery. These findings highlight the potential of Janus Mg 2+ /H 2 pump conduit as a promising approach for peripheral nerve defect repair by offering a conducive microenvironment.
研究领域:
神经科学
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生物材料学
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再生医学
✓ 已验证
产品关联
DOI
高影响因子
ACS ES&T Water
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2020
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IF 0
Huihui Zhao,Linyan Yang,Xueming Chen,Lankun Cai,Yejin Li,Mei Sheng,Guomin Cao,Qianhong She
The co-presence of haloacetic acids (HAAs) and Mg2+ in swimming pool waters and the potential interaction among Mg2+, HAAs, and membranes prompted a systematic investigation of membrane performance affected by Mg2+. The rejection behavior of the tight NF90 was not significantly affected by Mg2+ due to the predominant role of size exclusion. For loose NF270, HAA rejection and water flux were reduced by 27% and 12%, respectively, after the addition of 5 mM Mg2+. The notable magnesium content in NF270 exposed in Mg2+ indicated the binding of Mg2+ to membranes. The interaction between Mg2+ and membranes resulted in a less negatively charged and hydrophilic surface and a smaller effective pore radius for membranes. The reduction of the effective pore size by Mg2+ was verified as a result of competing effects between “-COO–-induced conformational change” and “cation-induced pore shielding”. The increased permeability for charged HAAs and NaCl in the presence of Mg2+ was mainly attributed to charge neutralization, while the reduced permeability for neutral surrogates and water was due to the reduced effective pore size and hydrophilicity. The underlying mechanism for resolving the interaction among different divalent cations, trace contaminants, and polyamide membranes may have significant implications for practical water purification by membrane technologies.
研究领域:
环境科学
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膜技术
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水处理工程
✓ 已验证
产品关联
DOI
Journal of Environmental Sciences
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2022
·
IF 6.796
Linjun Li,Jinsuo Lu,Heliang Pang,Zhiqiang Zhang,Jing Yang,Pengpeng Li,Xiaoyu Yan,Miaomiao Fan
Scale not only affects the taste and color of water, but also increases the risks of osteoporosis and cardiovascular diseases associated with drinking it. As a popular beverage, tea is rich many substances that have considerable potential for scale inhibition, including protein, tea polyphenols and organic acids. In this study, the effect of tea brewing on scale formation was explored. It was found that the proteins, catechins and organic acids in tea leaves could be released when the green tea was brewed in water with sufficient hardness and alkalinity. The tea-released protein was able to provide carboxyl groups to chelate with calcium ions (Ca 2+ ), preventing the Ca 2+ from reacting with the carbonate ions (CO 3 2− ). The B rings of catechins were another important structure in the complexation of Ca 2+ and magnesium ions (Mg 2+ ). The carboxyl and hydroxyl groups on the organic acids was able to form five-membered chelating rings with Ca 2+ and Mg 2+ , resulting in a significant decrease in Ca 2+ from 100.0 to 60.0 mg/L. Additionally, the hydrogen ions (H + ) provided by the organic acids consumed and decreased the alkalinity of the water from 250.0 to 131.4 mg/L, leading to a remarkable reduction in pH from 8.93 to 7.73. It further prevented the bicarbonate (HCO 3 − ) from producing CO 3 2− when the water was heated. The reaction of the tea constituents with the hardness and alkalinity inhibited the formation of scale, leading to a significant decrease in turbidity from 10.6 to 1.4 NTU. Overall, this study provides information to help build towards an understanding of the scale inhibition properties of tea and the prospects of tea for anti-scaling in industrial applications.
研究领域:
食品科学
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化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DESALINATION
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2017
·
IF 5.527
Hai-Zhen Zhang,Zhen-Liang Xu,Hao Ding,Yong-Jian Tang
High water permeability and good separation property are greatly desired in water production due to energy concerns. To explore nanofiltration (NF) membrane with high permeability for cations separation, a positively charged NF membrane was fabricated via interfacial polymerization using polyethersulfone (PES) three-channel capillary ultrafiltration (UF) membrane as substrate, polyethyleneimine (PEI) as the aqueous precursor. The NF membrane preparation conditions were optimized. To enhance the permeability of the prepared NF membrane, modified hydroxyl contained multi-walled carbon nanotubes (MWCNTs-OH), grafting with piperazine (PIP), were utilized. The resultant NF membrane showed increased water flux from 20.8 L·m − 2 ·h − 1 to 56.1 L·m − 2 ·h − 1 at 4 bar after adding 0.01 wt% modified MWCNTs-OH in aqueous solution. Interestingly, MgCl 2 rejection of the membrane also increased from 94.2% to 96.9%. The positively charged NF membrane exhibited above 97% rejection for divalent cations (Mg 2 + and Ca 2 + ) and low rejection (< 70%) for monovalent cations (Na + and Li + ), and it also showed long durability and good separation for Mg 2 + and Li + when the membrane was used to separate mixed salts solution simulated the composition of salt lake brine. The fabricated membrane would have potential for effective water softening and for reclamation of lithium from brine or seawater with high Mg 2 + /Li + ratio.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Zhiyuan Zhang,Zhihao Sun,Shibo Sun,Jinyu Liu,Jiqiong Jiang,Wei Shang,Yuqing Wen
As a kind of clean energy, magnesium batteries have become the main research direction of next-generation batteries. A long voltage lag time and irreversibility in aqueous electrolytes are problems faced by magnesium aqueous batteries. For the first time, we modified the anode of a magnesium aqueous battery with MXene . The modified battery not only reduced the voltage lag time of the battery but also improved the reversibility, cycle stability, and intermittent discharge performance of the magnesium aqueous battery. The calculation results of density functional theory showed that there is a high adsorption energy between MXene film and magnesium alloy . The calculation results of the ion diffusion energy barrier indicated that magnesium ions have a lower migration barrier on the surface of the MXene film layer. This research is of great significance to the development and application of magnesium batteries.
研究领域:
材料科学
·
能源存储技术
✓ 已验证
产品关联
DOI
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2021
·
IF 4.158
Wentai Zhang,Sheng Zhao,Xiaoshan Mo,Peng Xian,Shuai Tang,Junyu Qian,Gang Shen,Chao Zhou,Nan Huang,Haijun Zhang,Guojiang Wan
In this study, Mg ions incorporated phytic acid (PA) and zoledronic acid (ZA) of metal-organic complex coating was built on Mg substrate. This coating aims to fulfill the corrosion controlling and differential regulation on osteoblast vs. osteoclast responses simultaneously. PA and ZA molecules were co-immobilized on the alkaline pretreated Mg by a facile one-step dip-coating method. Such immobilization process was executed by the chelation reaction between PA/ZA molecules and in-situ released Mg ions. This coating showed a homogeneous structure with metal-organic like framework. The electrochemical corrosion resistance and long-term degradation behavior of coated samples were remarkably improved. Consequently, the well-controlled Mg ion release, as well as the osteo-compatible PA molecule, promoted the proliferation of pre-osteoblast cells (MC3T3-E1). Moreover, this coating significantly suppressed both the proliferation and differentiation of osteoclast cells owing to the nature of ZA. This metal-organic complex coating offers a promising modifying strategy for Mg-based orthopedic implants for osteoporotic fracture healing.
研究领域:
材料科学
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生物材料
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骨科
·
生物医学工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Guoshen Yang,Xianqi Xu,Gangrui Qu,Jie Deng,Yachao Zhu,Chi Fang,Olivier Fontaine,Pritesh Hiralal,Jiaxin Zheng,Hang Zhou
The earth-abundant magnesium resource and aqueous electrolyte make aqueous magnesium-ion batteries (AMIBs) a promising post-lithium-ion battery technology to synchronously address cost and safety concerns. Nonetheless, the freeze issue of aqueous electrolytes is curbing the development of AMIBs working at low-temperature conditions. Here, we report an MgCl 2 solution having a great low-temperature property via anion and concentration adjustment, which roots in the variation of the pristine hydrogen bond reticulation. Consequently, a 4 M MgCl 2 aqueous electrolyte endows a low freezing point (−62 °C) as well as ultra-high ionic conductivity (2.77 mS/cm at −50 °C). By using 4 M MgCl 2 as an electrolyte, the MnO 2 //VO 2 battery is capable of working in a wide temperature range from +25 to −50 °C, achieving a high discharge capacity of 97.9 mAh/g (0.1 A/g) and a high cycling capability of 1000 cycles (∼90 % capacity retention at −20 °C). Furthermore, MgCl 2 can be well compatible with polyacrylamide into an outstanding hydrogel electrolyte (in terms of mechanical property, anti-freeze performance, and high ionic conductivity) for a flexible quasi-solid-state MIBs application. The assembled flexible device attains appealing electrochemical properties across a broad temperature region, while the constructed pouch cell demonstrates superior flexibility and reliable safety. Our current exploration depicts an expeditious but productive paradigm for devising the high-performing AMIBs for low-temperature energy storage sectors.
研究领域:
电化学
·
材料科学
·
能量存储
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）