Nanomaterials
·
2022
·Vol. 12
·期 19
·3403
·
IF 5.719
Dandan Yan,Zhi Yu,Tingting Zou,Yucai Lin,Wenchi Kong,Jianjun Yang
The acquiring of superhydrophilic surfaces attracts the strong interest in self-cleaning, anti-fogging and anti-icing fields based on the unique features. However, the persistent time of superhydrophilic surfaces is still facing a big challenge because of easily adsorbing hydrophobic groups. Here, we propose a strategy to achieve a superhydrophilicity persisting for an unprecedently long time on sapphire surfaces, by compounding the femtosecond laser-induced hierarchical structures and the subsequent varnish of TiO2. The superhydrophilic effect (with a contact angle of CA = 0°) created by our method can be well prolonged to at least 180 days, even for its storage in air without additional illumination of UV lights. Based on comprehensive investigations, we attribute the underlying mechanisms to the coordination of laser-induced metal ions on the material surface via TiO2doping, which not only prevents the adsorption of the nonpolar hydrocarbon groups, but also modulates the photo-response properties of TiO2. In addition, further experiments demonstrate the excellent anti-fogging properties of our prepared samples. This investigation provides a new perspective for further enhancing the durability of superhydrophilicity surfaces.Keywords:femtosecond laser;long-time superhydrophilicity;sapphire;TiO2
研究领域:
材料科学
·
表面工程学
✓ 已验证
DOI
PubMed
高影响因子
Frontiers in Chemistry
·
2021
·
IF 5.221
Han Yubing,Zhang Zhimin,Liu Wenjie,Yao Yuanfa,Xu Yingke,Liu Xu,Kuang Cuifang,Hao Xiang
Despite the urgent need to image living specimens for cutting-edge biological research, most existing fluorescent labeling methods suffer from either poor optical properties or complicated operations required to realize cell-permeability and specificity. In this study, we introduce a method to overcome these limits—taking advantage of the intrinsic affinity of bright and photostable fluorophores, no matter if they are supposed to be live-cell incompatible or not. Incubated with living cells and tissues in particular conditions (concentration and temperature), some Atto and BODIPY dyes show live-cell labeling capability for specific organelles without physical cell-penetration or chemical modifications. Notably, by using Atto 647N as a live-cell mitochondrial marker, we obtain 2.5-time enhancement of brightness and photostability compared with the most commonly used SiR dye in long-term imaging. Our strategy has expanded the scientist's toolbox for understanding the dynamics and interactions of subcellular structures in living specimens.
研究领域:
分子生物学
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细胞生物学
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生物物理学
·
成像科学
✓ 已验证
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Haotian Jiang,Yanxiang Wang,Chengjuan Wang,Xiaodan Xu,Mengfan Li,Zhenhao Xu,Hongxue Tan,Yapeng Wang
Carbon nanotubes (CNTs)/carbon fiber (CF) reinforcements were prepared by chemical vapor deposition after electrochemical anodization and catalyst impregnation. The results showed that after the electrochemical anodization, the CFs were oxidatively etched and the surface roughness increased, which is helpful to form a uniform catalyst coating on the surface of CF. Under the current of 0.4 A and 0.6 A, CNTs can grow evenly on the surface of CF. Within a certain range, with the increase of growth time, the density and length of CNTs are improved. The CNTs/CF reinforcement prepared at the current intensity of 0.4 A and the growth time of 8 min has the best comprehensive performances compared with other as-fabricated samples. The tensile strength of the sample can reach a high value of 4.56 GPa, and the wettability of resin has an effective improvement.
研究领域:
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Microbiome
·
2025
·Vol. 13
·期 1
·1-17
·
IF 12.7
Liu Youhua,Liu Jiaqi,Ren Ruiti,Xin Zimeng,Luo Yaojun,Chen Yushi,Huang Chaoqun,Liu Yuxi,Yang Tongyudan,Wang Xinxia
Background Although short-term high-fat diet (S-HFD) and long-term high-fat diet (L-HFD) induce metabolic disorder, the underlying epigenetic mechanism is still unclear. Results Here, we found that both 4 days of S-HFD and 10 weeks of L-HFD increased mRNA m 6 A level in epididymal white adipose tissue (eWAT) and impaired metabolic health. Interestingly, S-HFD activated transposable elements (TEs), especially endogenous retroviruses (ERVs) in eWAT, while L-HFD activated long interspersed elements (LINEs). Subsequently, we demonstrated that both S-HFD and L-HFD increased m 6 A level of Ehmt2 and decreased EHMT2 protein expression and H3K9me2 level, accounting for activation of ERVs and LINEs. Overexpression of EHMT2 in eWAT or inhibition of ERVs and LINEs by antiviral therapy improved metabolic health under HFD feeding. Notably, we found that both short-term and long-term HFD feeding increased Fimicutes/Bacteroidota ratio and decreased the gut microbiome health index. Fecal microbiota transplantation (FMT) experiments demonstrated that gut microbiota from S-HFD and L-HFD was responsible for increased m 6 A level in eWAT, resulting in glucose intolerance and insulin insensitivity. Furthermore, we identified that both S-HFD and L-HFD increased the abundance of the gut microbial metabolite homogentisic acid (HGA), and HGA level was positively correlated with unclassified_f__Lachnospiraceae which was both increased in S-HFD and L-HFD feeding mice. Administration of HGA increased the m 6 A level of Ehmt2 and decreased the EHMT2 protein expression and H3K9me2 level in eWAT, leading to metabolic disorder in mice. Conclusions Together, this study reveals a novel mechanism that S-HFD and L-HFD induce metabolism disorder through gut microbiota-HGA-m 6 A- Ehmt2 -ERV/LINE signaling. These findings may provide a novel insight for prevention and treatment of metabolism disorder upon short-term or long-term dietary fat intake.
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研究领域:
分子生物学
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营养学
·
微生物学
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产品关联
DOI
PubMed
高影响因子
InfoMat
·
2025
·
IF 22.3
Mingxuan Zhang,Mingming Hao,Guoqiang Ren,Yinchao Zhao,Chujie Lv,Yizhang Xia,Wei Wang,Wei Chen,Yi Chen,Lianhui Li,Qifeng Lu,Ting Zhang
Prolonged sitting is a major risk factor for lumbar spine disorders, significantly affecting both physical and mental health. However, conventional clinical diagnosis primarily relies on imaging evaluations conducted after symptom onset, often missing opportunities for early intervention and allowing for disease progression. To address this, this paper presents a diagnostic method based on electromyography (EMG) using an adaptive flexible electromyography sensor (FES). The FES consists of a thermo-responsive in situ gelation hydrogel and flexible mesh electrode patch. The hydrogel undergoes a sol–gel transition at body temperature, enabling conformal skin contact and strong adhesion. As a result, the adhesion of the FES is 15 times stronger than that of conventional EMG electrodes. Consequently, the contact impedance is significantly reduced to 40 kΩ/cm 2 at 10 Hz, and a high signal-to-noise ratio of 23.28 dB is achieved, allowing for the effective monitoring of subtle electrophysiological signals during prolonged sitting. Overall, this research provides a foundation for the early-stage diagnosis of lumbar disorders, facilitating the transition of lumbar disease management from reactive treatment to proactive prevention.
研究领域:
生物医学工程
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康复医学
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神经电生理学
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可穿戴传感器
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脊柱健康监测
✓ 已验证
产品关联
DOI
高影响因子
Nature Energy
·
2023
·
IF 56.7
Lei Jiafeng,Zhang Yaqin,Yao Yanxin,Shi Yang,Leung Ka Lok,Fan Jun,Lu Yi-Chun
Aqueous redox flow battery (RFB) is one of the most promising technologies for grid-scale energy storage systems. Polysulfides are particularly attractive active materials owing to their low cost and high capacity, but the low energy efficiency and low operating current density limit their practical applications. Here we report an active and durable molecule catalyst, riboflavin sodium phosphate (FMN-Na), to transform sluggish polysulfide reduction reactions to fast redox reactions of FMN-Na via homogeneous catalysis. The FMN-Na catalyst substantially reduces the overpotential of a polysulfide–ferrocyanide RFB (S-Fe RFB) from more than 800 mV to 241 mV at 30 mA cm − 2 . A catalysed S-Fe flow cell was demonstrated for 2,000 cycles at 40 mA cm − 2 with a low decay rate of 0.00004% per cycle (0.0017% per day). A catalysed polysulfide–iodide RFB operated for 1,300 cycles under 40 mA cm − 2 without capacity decay. This work addresses the bottleneck of polysulfide-based RFBs for long-duration energy storage applications.
研究领域:
储能技术
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电化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2016
·
IF 3.993
Yichuan Hu,Bo Liang,Lu Fang,Guanglong Ma,Guang Yang,Qin Zhu,Shengfu Chen,Xuesong Ye
In this study, a versatile fabrication method for coating enzyme-based biosensors with ultrathin antifouling zwitterionic polymer films to meet the challenge of the long-time stability of sensors in vivo was developed. Electrochemically mediated atom transfer radical polymerization (eATRP) was applied to polymerize zwitterionic sulfobetaine methacrylate monomers on the rough enzyme-absorbed electrode surfaces; meanwhile, a refined overall bromination was developed to improve the coverage of polymers on the biosensor surfaces and to maintain the enzyme activity simultaneously for the first time. X-ray photoelectron spectroscopy and atomic force microscopy were used to characterize the properties of the polymer layers. The antifouling performance and long-time stability in 37 °C undiluted bovine serum in vitro were evaluated. The results showed that the polymer brush coatings diminished over 99% nonspecific protein adsorption and that the sensitivity of the evaluated sensor was maintained at 94% after 15 days. The overall sensitivity deviation of 7% was nearly 50% lower than that of the polyurethane-coated ones and also much smaller than the current commercially available glucose biosensors. The results suggested that this highly controllable electrodeposition procedure could be a promising method to develop implantable biosensors with long-time stability.
研究领域:
生物传感器
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聚合物化学
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材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2021
·Vol. 12
·期 1
·1-12
·
IF 14.919
Zhao Yan,Zhang Song,Yu Tianhao,Zhang Yan,Ye Guo,Cui Han,He Chengzhi,Jiang Wenchao,Zhai Yu,Lu Chunming,Gu Xiaodan,Liu Nan
Accurate and imperceptible monitoring of electrophysiological signals is of primary importance for wearable healthcare. Stiff and bulky pregelled electrodes are now commonly used in clinical diagnosis, causing severe discomfort to users for long-time using as well as artifact signals in motion. Here, we report a ~100 nm ultra-thin dry epidermal electrode that is able to conformably adhere to skin and accurately measure electrophysiological signals. It showed low sheet resistance (~24 Ω/sq, 4142 S/cm), high transparency, and mechano-electrical stability. The enhanced optoelectronic performance was due to the synergistic effect between graphene and poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), which induced a high degree of molecular ordering on PEDOT and charge transfer on graphene by strong π-π interaction. Together with ultra-thin nature, this dry epidermal electrode is able to accurately monitor electrophysiological signals such as facial skin and brain activity with low-motion artifact, enabling human-machine interfacing and long-time mental/physical health monitoring.
研究领域:
可穿戴技术
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生物医学工程
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电生理学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Lina Ning,Xianhu Liu,Min Deng,Zhengzheng Huang,Aimei Zhu,Qiugen Zhang,Qinglin Liu
The excellent catalyst need to meet low cost, long-time stability and high electrocatalytic activity in direct ethanol fuel cells (DEFC). Here, carbon nanotube-supported Pd-based (Pd/CNT, PdSn/CNT, PdNi/CNT and PdSnNi/CNT) catalysts were synthesized by microwave-assisted polyols and in-situ reduction. Compared with commercial Pd/C (JM), the as-prepared Pd-based catalysts have higher electrocatalytic activity and outstanding long-time durability toward ethanol electro-oxidation reaction in alkaline media. The enhanced electrocatalytic activity of Pd-based catalysts are owning to high electrochemically active surface area (ECSA) and modified electronic structure of Pd. After chronoamperometric test, the current densities of Pd-based catalysts can be reactivated by simple cycle potential scan in 1 M NaOH, which indicated that all of them have excellent resistance to CO poisoning.
研究领域:
材料科学
·
电化学
·
催化
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
DALTON TRANSACTIONS
·
2024
·
IF 3.5
Ziyi Chen,Xiaomin Zhang,Qiwei Duan,Guangming Wang,Shuchun Li,Kaihua Yu,Changsheng Cao,Zailai Xie
Non-metallic heteroatom-doped carbon materials are promising catalysts for the oxidative dehydrogenation of propane (ODHP), but their controlled synthesis remains challenging. Herein, a novel three-dimensional N, P co-doped carbon nanosheet (NPC-NS-T) catalyst is prepared, which shows an impressive catalytic performance in the ODHP reaction with high propane conversion (20.0%) and high selectivity for propene (62.1%) and olefins (64.5%) at 500 °C along with good long-time stability. Comprehensive experimental characterizations revealed that incorporation of appropriate P can not only help to form more CO species on the surface of NPC-NS-T but also inhibit the consumption of CO species under ODHP conditions, thereby remarkably improving the catalytic performance. This work could pave the way for developing efficient biomass-derived carbon catalysts for the oxidative dehydrogenation reactions of propane.
研究领域:
催化
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Ye Zhang,Yajing Shen,Xiyao Teng,Manqing Yan,Hong Bi,Paulo Cesar Morais
In this study, a biocompatible nanoplatform has been constructed on the basis of magnetic mesoporous silica nanoparticles (Fe3O4@mSiO2) via surface modification of triphenylphospine (TPP) and then conjugation with fluorescent carbon dots (CDs). The as-prepared Fe3O4@mSiO2–TPP/CDs nanoplatform shows a very low cytotoxicity and apoptosis rate in various cell lines such as A549, CHO, HeLa, SH-SY5Y, HFF, and HMEC-1. More importantly, this nanoplatform integrates long time cell imaging, mitochondria-targeting, and magnetic field-enhanced cellular uptake functionalities into an all-in-one system. Time-dependent mitochondrial colocalization in all of the cell lines has been proved by using confocal laser scanning microscopy and flow cytometry, while the multicolored fluorescence of the Fe3O4@mSiO2–TPP/CDs could remain bright and stable after coincubation for 24 h. In addition, the cellular uptake efficiency could be enhanced in a short time as a static magnetic field of 0.30 T was applied to the coincubation system of A549 and HFF cell lines. This bionanoplatform may have potential applications in targeted drug delivery for mitochondria diseases as well as early cancer diagnosis and treatment.
研究领域:
纳米技术
·
生物材料
·
细胞生物学
·
癌症研究
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2015
·Vol. 39
·期 5
·4020-4025
·
IF 3.086
Di Wu,Lingling Song,Zhenping Qi,Dapeng Qu
Multi-modal imaging in tissue and animals has integrated the advantages of individual molecular imaging modalities and shown great potential in both pre-clinical and clinical fields. In the present work, a high-performance nanoparticulate contrast agent based on PEGylated gadolinium hydroxycarbonate nanoparticles (PEG-GdNPs) was designed and synthesized via a facile approach. Due to the outstanding X-ray absorption coefficient/K-edge value and the presence of unpaired 4f electrons of element Gd, our well-prepared nanoprobes were successfully used as dual-modal contrast agents for in vivo synergistic magnetic resonance and X-ray computed tomography imaging. Bio-distribution of the nanoparticles was further studied via in vivo long-term tracking during the imaging process, revealing that most of the nanoprobes could accumulate in the liver and therefore act as a liver-targeted imaging agent. Moreover, toxicity including cell viability, blood biochemical assay, as well as changes in body weight and histology indicated the low systemic toxicity of our nanoprobes. Taken together, we believe that PEG-GdNPs with their excellent imaging capability and high biocompatibility may find widespread application in the field of biomedicine.
研究领域:
医学影像
·
纳米技术
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）