Colloid and Interface Science Communications
·
2018
·
IF 0
Jindan Wu,Chong Zhang,Shuting Xu,Xiaoyu Pang,Guoqiang Cai,Jiping Wang
Recently, antibacterial textiles have gained interest from scientists due to their potential to provide protection and high-quality life to people. In this study, zwitterionic poly(sulfobetaine methacrylate) (pSBMA) brushes were grafted onto cotton fabrics via reactive dye intermediate reaction and surface-initiated atom transfer radical polymerization (SI-ATRP) technology. Two bacterial species (Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli ) was used for bacterial attachment experiments. The capability of resisting nonspecific protein adhesion, short-term bacterial attachment (24 h) and long-term biofilm formation (120 h) of pSBMA-grafted cotton fabrics were studied. The results suggested that the pSBMA-grafted cottons exhibited an excellent non-fouling performance. Different from the studies on two-dimensional surfaces, our study provides an insight into the long-term biofilm resisting properties of porous textiles grafted with zwitterionic polymers.
研究领域:
材料科学
·
生物学
·
纺织工程
✓ 已验证
产品关联
DOI
INDUSTRIAL CROPS AND PRODUCTS
·
2022
·
IF 6.449
Xiaoming Song,Luyao Zhang,Yan Wang,Rui Zhao,Xiuxiu Sun,Yue Tian,Ruru Sun,Chenghao Hua,Rujin Bai,Chuansheng Wang,Shanshan Gao
Cellulose products such as textile, paper, package and so on are apt to breed bacterial. In this study, AA-PHMB antibacterial agent was synthesized innovatively. It was grafted onto cellulose by the addition polymerization of carbon carbon double bonds and hydroxyl groups to prepare cellulose antibacterial film with excellent performance. The structures, elements, mechanical properties and antibacterial activities of films were studied. The results showed that C N absorption at 1631 cm −1 of guanidine and the amide group absorption peak at 1554 cm −1 appeared on cellulose graft copolymers ; employing SEM-EDS, a great quantity of deposited materials, with the elements of C, O and N, were observed on the grafted cellulose. The graft percentage of cellulose-AA-PHMB was about 62%. Compared with unmodified cellulose films , the mechanical properties of PHMB-AA-cellulose film were lower, and the crystallinity of the PHMB-AA-cellulose film was lower than that of original cellulose film. The modified film as a raw material had a good inhibitory effect on Escherichia coli and Staphylococcus aureus was proved by bacteriostatic experiments. Under the condition of continuous culture for 15 days, it still had a good bacteriostatic effect on the above strains, and therefore the cellulose-AA-PHMB films were long term antibacterial effect materials.
研究领域:
材料科学
·
生物学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Shuang Chen,Si Chen,Xuming Liu,Xin Liu,Qin Zhang,Guanghui Gao
Moisture-electric generators (MEGs) are an emerging clean and accessible next generation of green power generation equipment. However, most hygroscopic materials used for MEGs still face challenges of low moisture absorption capacity and lack of anti-bacterial properties, resulting in low output voltage and poor long-term stability. In this work, a liquid-free antibacterial ionic conductive elastomer-based MEG was designed using L-carnitine/glycerol deep eutectic solvent with outstanding mechanical properties and great self-healing ability. Benefiting from the superb hygroscopic ability and ion transport capability, the assembled MEGs can spontaneously generate electricity over a wide relative humidity (RH) range from 30 % to 90 %, which can continuously output 0.83 V of voltage and 57.82 µA of current under 90 % RH for 6 h without obvious electrical performance degradation. Moreover, the MEGs can be directly used for breath monitoring and touch sensing. In addition, the ionic conductive elastomers exhibit long-term antibacterial ability, which ensures that the MEGs work stably for a long time. This work provides a feasible and efficient strategy to construct a green and high-performance energy source for sustainable and long-term applications.
研究领域:
材料科学
·
能源技术
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Chaoqun Liu,Shan Feng,Longyu Ma,Mengyao Sun,Zhihong Wei,Jiaqi Wang,Zhaowei Chen,Yuheng Guo,Jiahua Shi,Qiang Wu
Biofilms formed on urinary catheters remain a major headache in the modern healthcare system. Among the various kinds of biocide-releasing urinary catheters that have been developed to prevent biofilm formation, Ag nanoparticles (AgNPs)-coated catheters are of great promising potential. However, the deposition of AgNPs on the surface of catheters suffers from several inherent shortcomings, such as damage to the urethral mucosa, uncontrollable Ag ion kinetics, and unexpected systematic toxicity. Here, AgNPs-decorated amphiphilic carbonaceous particles (ACPs@AgNPs) with commendable dispersity in solvents of different polarities and broad-spectrum antibacterial activity are first prepared. The resulting ACPs@AgNPs exert good compatibility with silicone rubber, which enables the easy fabrication of urinary catheters using a laboratory-made mold. Therefore, ACPs@AgNPs not only endow the urinary catheter with forceful biocidal activity but also improve its mechanical properties and surface wettability. Hence, the designed urinary catheter possesses excellent capacity to resist bacterial adhesion and biofilm formation both in vitro and in an in vivo rabbit model. Specifically, a long-term antibacterial study highlights its sustainable antibacterial activity. Of note, no obvious toxicity or inflammation in rabbits was triggered by the designed urinary catheter in vivo. Overall, the hybrid urinary catheter may serve as a promising biocide-releasing urinary catheter for antibacterial and antibiofilm applications.
研究领域:
材料科学
·
生物材料
·
生物医学工程
·
微生物学
·
医疗器械
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2023
·
IF 6.6
Xinlei Wu,Jun Yao,Yingjie Guo,Sijia Zheng,Zhihai Cao
Construction of long-term antibacterial surfaces is highly challengeable but of great academic and social significance. Herein, a strategy integrating the foulant-release property with synergistically bactericidal action is designed to endow the surfaces with long-term antibacterial ability. To fulfill this design principle, quaternized fluoropolymer/Ag composite films (FP-Q x /Ag CFs) were conveniently fabricated via sequential miniemulsion polymerization and squeegeeing techniques. The crucial effect of the alkyl chain length of quaternary ammonium (QA) units on the particle properties and antibacterial ability of quaternized fluoropolymer/Ag nanocomposite particles (FP-Q x /Ag NCPs), as well as the surface properties, surface energy, underwater surface reconstruction, and antibacterial ability of FP-Q x /Ag CFs was disclosed. The long-term antibacterial performance of the FP-Q x /Ag CFs against both regular and multi-drug resistant bacteria depended on the alkyl chain length of QA units. The respective role of surface energy and surface rearrangement, as well as the synergistic bactericidal ability of FP-Q x /Ag CFs that could be manipulated by the alkyl chain length of QA units in the long-term antibacterial performance was decoupled to propose a comprehensive long-term antibacterial mechanism. Our work may guide the design of long-term antibacterial surfaces and provide an effective method to manipulate the property and performance of antibacterial surfaces via alkyl side chain engineering.
研究领域:
材料科学
·
化学工程
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2018
·
IF 5.089
Liming Ge,Mingjin Zhu,Xinying Li,Yongbin Xu,Xiaonan Ma,Rong Shi,Defu Li,Changdao Mu
It is significant to develop new approaches to incorporate naturally active agents into gelatin-based edible films for effective antioxidant and long-term antibacterial activities. Here the naturally active compound rosmarinic acid (RosA) was firstly conjugated onto gelatin backbone via EDC/NHS chemistry. Then the conjugates were plasticized by glycerol and crosslinked by dialdehyde xanthan gum to fabricate active RosA-gelatin edible films. The results indicate that the RosA-gelatin edible films present good water resistance property, strong mechanical property and excellent ultraviolet light barrier ability. The conjugation of RosA confers gelatin-based edible films with effective antioxidant and antibacterial activities as expected. It is interesting that RosA-gelatin edible films after 3 months of storage still show good antibacterial activity as that of newly prepared ones, demonstrating the long-term antibacterial activity. Overall, the fabricated RosA-gelatin edible films may have promising application in the fields of food and pharmaceutical packaging.
研究领域:
材料科学
·
食品科学
·
药学
·
生物技术
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Xinlei Wu,Jun Yao,Yingjie Guo,Sijia Zheng,Yifang Mi,Zhihai Cao
Durable antibacterial surfaces are often required high bactericidal ability and low bacterial adhesion property, but the potent bactericidal surfaces, especially based on the contact bactericidal mechanism, are often paradoxically intended to attract bacteria to adhere. In this work, a delicate balance between the potent contact bactericidal action and low bacterial adhesion was successfully achieved in quaternized fluoropolymer/SiO 2 composite films (QFP/SiO 2 CFs) through judicious selection of a common fluorinated monomer, a common quaternary ammonium monomer, and a common inert inorganic nanoparticle, to acquire suitable surface energy and chain mobility to ensure low bacterial adhesion, as well as to allow appropriate surface-exposed quaternary ammonium units to synergistically enhance the contact bactericidal action with the specific fluorinated side chains. The QFP/SiO 2 CFs were conveniently fabricated through miniemulsion polymerization and followed squeegeeing technique. The QFP/SiO 2 CF with an optimized composition exhibited extremely low initial adhesion of bacteria, potent contact bactericidal action, superior long-term antibacterial performance, easy sonication-assistant regeneration for multiple usage, and low cytotoxicity with non-leachable attribute. This work may guide the design and efficient fabrication of leaching-free durable antibacterial surfaces for biological applications, as well as provide an effective strategy to balance contact bactericidal action and low bacteria adhesion for durable antibacterial performance.
研究领域:
材料科学
·
高分子科学
·
生物医学工程
·
表面化学
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2020
·Vol. 31
·期 12
·125101
·
IF 3.551
Jingchen Li,Jie Zheng,Yadong Yu,Zhen Su,Lihui Zhang,Xiaojun Chen
The abuse of antibiotics has led to the emergence of numerous super resistant bacteria, which pose a serious threat to public health. Developing nanomaterials with novel modes of bactericidal activity offers the promise of fighting pathogens without the risk of causing drug resistances. Here, we used reduced graphene oxide (rGO), bulk molybdenum disulfide (MoS2) and silver nitrate (AgNO3) to synthesize a ternary nanocomposite, rGO–MoS2–Ag, via a simple one-pot method. The resulting rGO–MoS2–Ag presented as crumpled and sheet-like structures decorated with Ag nanoparticles. The minimum inhibitory concentration and minimum bactericidal concentration of rGO–MoS2–Ag against Escherichia coli were 50 and 100 μg ml−1, while Staphylococcus aureus reacted only to twice higher concentrations of 100 and 200 μg ml−1, respectively. Notably, rGO–MoS2–Ag exhibited better antibacterial activity towards E. coli and S. aureus than rGO, MoS2, or rGO–MoS2. This result can be attributed to the excellent performance of rGO–MoS2–Ag in destroying the bacterial cell membrane and inducing the generation of reactive oxygen species. The Ag+ ion release of rGO–MoS2–Ag was delayed, endowing the nanocomposite with long-term antibacterial capabilities and better biosafety. Our results indicate that the as-prepared rGO–MoS2–Ag has promising potential for application in biomedicine and public health.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）