CARBOHYDRATE POLYMERS
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2023
·
IF 11.2
Suning Zhang,Tongshu Wang
In this paper, a natural composite wall material sunscreen microcapsule was prepared, which significantly improved the SPF value and photostability of the embedded sunscreen agents. Using modified porous corn starch and whey protein as wall materials, the sunscreen agents 2-[4-(diethylamino)-2-hydroxybenzoyl] benzoic acid hexyl ester and ethylhexyl methoxycinnamate were embedded by adsorption, emulsion, encapsulation and solidification. The embedding rate of the obtained sunscreen microcapsules was 32.71 % and the average size was 7.98 μm; the enzymatic hydrolyzed starch formed a porous structure, its X-ray diffraction pattern did not change significantly, and the specific volume and oil absorption rate increased by 39.89 % and 68.32 %, respectively, compared with those before enzymatic hydrolyzed; The porous surface of the starch after embedding the sunscreen was covered and sealed with whey protein. 120 h sunscreen penetration rate was lower than 12.48 %; Compared with the lotion containing the same amount of sunscreen but not encapsulated, the SPF value of the lotion containing sunscreen microcapsules increased by 62.24 %, and the photostability of sunscreen microcapsules increased by 66.28 % within 8 h under the irradiation intensity of 25 w/m 2 . The wall material and the preparation method are natural and environmentally friendly, and have a good application prospect in low-leakage drug delivery system.
研究领域:
材料科学
·
生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Ying Wu,Jie Gao,Jian-Hui Li,Bo-Kun Chen
Lignin has potential to serve as promising sunscreen agents as it has good ultraviolet (UV) absorption and antioxidant properties. However, the weak absorption capacity of lignin in the long-wave UV region (UVA, 320–400 nm) limits its further development. In this work, a spiropyran-modified lignin (DLSP) with photo-responsive property was prepared by in-situ construction of spiropyran (SP) structure in the demethylated lignin (DL). Due to the presence of SP moiety, the absorption of DLSP in the UVA region was significantly improved. Under UV irradiation, its absorption peak was redshifted as unconjugated SP form isomerized to conjugated merocyanine (MC) form, and the UVA/UVB ratio increased from 0.62 to 0.74. The free-radical scavenging ability of lignin could protect SP from photodegradation , which provided DLSP excellent fatigue resistance. DLSP were blended into creams to investigate its sunscreen performance. Results indicated that DLSP exhibited radiation-enhanced sunscreen performance, the sun protection factor (SPF) of cream containing 10 wt% of DLSP improved from 20 to 67 after 8 h of UV irradiation. Moreover, DLSP showed low skin penetration and good biocompatibility. These results provide a useful guideline for the rational design of sunscreens with special functionalities.
研究领域:
材料科学
·
生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Ying Wu,Meng Guo,Jie Gao,Jian-Hui Li,Bo-Kun Chen
The active ingredients most commonly employed in sunscreens are compounds containing one or two aromatic rings. Lignin is the most abundant renewable aromatic polymer that has the potential to yield low molecular weight aromatic chemicals when strategically depolymerized. Here, the UV absorbance of a series of monomeric and dimeric lignin model compounds (LMCs) were studied. Specifically, vanillin and ferulic acid demonstrated good absorption in the UVB (280–320 nm) range, while the 5–5 dimer showed efficient absorption in the UVA (320–400 nm) range. Based on this, vanillin, ferulic acid and 5–5 dimer were mixed in pairs and dispersed in the oily isoeugenol to prepare LMC hybrid dispersions. Subsequently, demethylated lignin (DL) was synthesized and used to encapsulate the LMC hybrid dispersions via ultrasonic cavitation to prepare DL-based nano-capsules (DLNCs). The DLNCs were used as the only active ingredient in sunscreens, whose sun protection factor (SPF) value could be up to 55 with a dosage of 10 wt%. Due to anti-photolysis property of DL, the SPF value of DLNCs-based sunscreens increased initially and maintained >8 h under UV irradiation. Additionally, the prepared DLNCs exhibited excellent anti-permeability, antioxidant capacity and biocompatibility, making them a potential substitute for conventional petroleum-based sunscreen agents.
研究领域:
化学工程
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材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2020
·
IF 3.573
Ying Wu,Yong Qian,Aicheng Zhang,Hongming Lou,Dongjie Yang,Xueqing Qiu
To solve the poor absorbance on ultraviolet A (UVA) radiations and dark color, alkali lignin (AL) was modified via atom transfer radical polymerization (ATRP) grafting of 2-4-benzoyl-3-hydroxyphenyl acrylate (BHA). The color of AL was whitened 86% and the UVA/UVB absorbance ratio of AL-g-BHA improved to 1.2, while the reported highest value was 0.9. The excellent UV-blocking performance of AL-g-BHA was demonstrated in sunscreen. Sun protection factor (SPF) value of the sunscreen containing 10 wt % of optimal AL-g-BHA reached 59. Nanoscale AL-g-BHA normal and reverse micelles (LBNM and LBRM) were fabricated to investigate the effect of microstructure on the sunscreen performance. When BHA chains were packed inside, the SPF value of sunscreen containing 10 wt % of LBNM decreased to 28. In contrast, the SPF value of sunscreen containing 10 wt % of LBRM with BHA chains distributing on the surface was up to 244. Both AL-g-BHA and corresponding micelles exhibited good biocompatibility.
研究领域:
材料科学
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生物学
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化学工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2016
·
IF 5.31
Xiaoling Zhang,Mingbao Feng,Liansheng Wang,Ruijuan Qu,Zunyao Wang
Recently, the toxicity of sunscreen has received extensive attention due to their potential endocrine disrupting effect. In the present study, nitrogen and sulfur co-doped multi-walled carbon nanotubes loaded CuFe 2 O 4 (NS-CNTs/CuFe 2 O 4 ) catalyst was rationally designed and synthesized by co-precipitation method for the degradation of 2-phenylbenzimidazole-5-sulfonic acid (PBSA, a typical sunscreen addition). The catalyst was fully characterized by scanning electron microscope, transmission electron microscope, X-ray diffraction, Fourier transform infrared spectroscopy, nitrogen gas uptake, and X-ray photoelectron spectroscopy. Then the kinetics, pathways and mechanisms of catalytic degradation of PBSA were studied in NS-CNTs/CuFe 2 O 4 activated peroxymonosulfate (PMS) solution. The catalyst showed high catalytic activity, stability and reusability in PBSA removal. The results of electron paramagnetic resonance (EPR) and quenching experiments suggested that sulfate radicals (SO 4 − ) predominated in the activation of PMS by NS-CNTs/CuFe 2 O 4 . The synergistic effect between CuFe 2 O 4 and NS-CNTs was proposed in PMS activation. In addition, eight degradation intermediates of PBSA were identified by liquid chromatography mass spectrometry (LC–MS), and degradation pathways were further proposed. Overall, this study provides insights of PBSA removal by NS-CNTs/CuFe 2 O 4 activated PMS at ambient temperature.
研究领域:
环境科学
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材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
·
IF 9.224
Aicheng Zhang,Xuwen Wu,Xinping Ouyang,Hongming Lou,Dongjie Yang,Yong Qian,Xueqing Qiu
Inspired by the UV-blocking of lignin in plants and the adhesion of catechol in mussel dopamine, light-colored lignin-based microcapsules ((OMC + BMDM)/LS-OH3-T) with strengthened UV-blocking and good bioadhesion were obtained by demethylation modification of sodium lignosulfonate (LS) and encapsulation of chemical sunscreen actives. The results show that the adhesion between LS and skin improved from 0.158 to 0.173 mN/m due to the formation of catechol groups. When (OMC + BMDM)/LS-OH3-T was used as the unique active ingredient in the sunscreen, the sun protection factor (SPF) reached 86.67, fully meeting the daily sunscreen requirement. In addition, the color of microcapsule-based sunscreen was close to pure white, which effectively solves the dark color problem of the existing lignin-based sunscreens. As it demonstrates good biocompatibility, this new light-colored lignin-based sunscreen agent has good application potential in the skincare field.
研究领域:
材料科学
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生物学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2021
·Vol. 13
·期 6
·866
·
IF 4.329
Chuntao Xu,Xuemin Zeng,Zujin Yang,Hongbing Ji
Octyl methoxycinnamate (OMC) is widely used as a chemical sunscreen in sunscreen cosmetics. However, its direct contact with the skin would bring certain risks, such as skin photosensitive reaction. How to improve the effect of skin photodamage protection has become a current research hotspot. Encapsulating ultraviolet (UV) filters into microcapsules is an interesting method to increase the photostability of filters. In this study, sodium caseinate (SC) and arabic gum (GA) are chosen as wall materials to prepare synergistic sunscreen microcapsules by complex coacervation technology. A series of experiments are conducted to investigate the effects of pH, wall material concentration, and wall/core ratio on the formation of OMC microcapsules. The morphology, composition, and stability of OMC microcapsules are characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The OMC microcapsule is uniform in size distribution, smooth in surface morphology, and has good thermal stability. The results show that the ultraviolet absorption of the OMC microcapsules is better than that of the uncoated OMC for the ultraviolet-B (280–320 nm). Moreover, the OMC microcapsule released 40% in 12 h, while OMC released 65%, but the sun protection factor (SPF) of the OMC microcapsule sunscreen is 18.75% higher than that of OMC. This phenomenon may be attributed to the hydrophobic interaction between SC and OMC and the electrostatic interaction between SC and GA.Keywords:octyl methoxycinnamate;sunscreen;microcapsule;complex coacervation;synergistic effects
研究领域:
生物学
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材料科学
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化妆品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2023
·Vol. 33
·期 43
·2303889
·
IF 19
Ying Wu,Xuwen Wu,Aicheng Zhang,Xinping Ouyang,Hongming Lou,Dongjie Yang,Yong Qian,Xueqing Qiu
Lignin exhibits a long-active UV-blocking property due to its macromolecular aromatic structure and unique semiquione-quione-hydroquione transition. However, its poor absorbance in UVA region (320–400 nm) and irregular aggregation are still the obstacles. Herein, active spirapyrane (SP-Br) is synthesized and covalently introduced into alkali lignin (AL) to construct photo-stimulated UV-absorbing enhancement sunscreen actives (AL-SP n ). The introduction of SP significantly improved the absorbance of AL in UVA region and its aggregation is effectively eased. When the optimal AL-SP 3 solution is exposed to UV irradiation, the color turned purple, and the absorbance in UVA region further improved as the unconjugated SP transformed into conjugated merocyanine (MC) structure. When the light is removed, the solution recovered light yellow. The antioxidant property of AL endow the reversible SP-MC transformation with good cyclic stability. As-prepared AL-SP 3 based sunscreen exhibit obvious photo-stimulated enhancement effect. The sun protection factor (SPF) improved from 23 to 89 after 4 h irradiation, and can maintain the high performance for another 8 h. In addition, it exhibit low permeation and good biocompatibily in vitro and vivo, demonstrating its good potential in practical use.
研究领域:
材料科学
·
化学工程
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）