APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Chitengfei Zhang,Liuyi Cai,Rong Tu,Yingqiu Zheng,Bao-Wen Li,Song Zhang
Due to its nontoxicity, suitable bandgap, high defect tolerance and high electron mobility, layered BiI 3 has been gaining attention in photoelectric device and nonlinear optics field. However, the growth of large-size single crystal 2D BiI 3 has not been achieved. Herein, the synthesis of single crystal 2D BiI 3 on mica substrate via a cooling-induced growth method is reported, with the thickness of 8 ∼ 1000 nm and a lateral dimension of 110 ∼ 1000 μm. X-ray diffraction and selected area electron diffraction demonstrate the single crystal nature of 2D BiI 3 flakes. The high temperature during heat preservation step prevents the deposition of BiI 3 vapor, and then, when proceeding to cooling-induced growth step, single crystal 2D BiI 3 flakes start to nucleate on colder mica substrate and grow up to ∼ 1000 μm (lateral dimension) rapidly. The stability test indicates the 2D BiI 3 flake decomposes with the present of both O 2 and water. Finally, the cooling rate, height of crucible, holding temperature and type of substrate have also been investigated to show the structural evolution of 2D BiI 3 flakes.
研究领域:
材料科学
·
凝聚态物理
·
纳米材料
·
晶体生长
·
光电器件
✓ 已验证
DOI
高影响因子
Small Methods
·
2024
·
IF 10.7
Chen-Yan Zheng,Hai-Long Qian,Cheng Yang,Xiu-Ping Yan
Nanochannel membranes are promising materials for enantioselective sensing. However, it is difficult to make a compromise between the selectivity and permeability in traditional nanochannel membranes. Therefore, new types of nanochannel membranes with high enantioselectivity and excellent permeability should be explored for chiral analysis. Here, asymmetric catalysis strategy is reported for interfacial polymerization synthesis of chiral covalent-organic framework (cCOF) nanochannel membrane for enantioselective sensing. Chiral phenylethylamine ( S / R -PEA) and 2,4,6-triformylphloroglucinol (TP) are used to prepare chiral TP monomer. 4,4′,4″-triaminotriphenylamine (TAPA) is then condensed with chiral TP to obtain cCOF nanochannel membrane via a C═N Schiff-base reaction. The molar ratio of TP to S/R -PEA is adjusted so that S/R -PEA is bound to the aldehyde only or both the aldehyde and hydroxyl groups on TP to obtain chiral-induced COF (cCOF-1) or both chiral-induced and modified COF (cCOF-2) nanochannel membrane, respectively. The prepared cCOF-2 nanochannel membrane showed two times more selectivity for limonene enantiomers than cCOF-1 nanochannel membrane. Furthermore, cCOF-2 nanochannel platform exhibited excellent sensing performance for other chiral molecules such as limonene, propanediol, methylbutyric acid, ibuprofen, and naproxen (limits of detection of 19–42 ng L −1 , enantiomer excess of 63.6–86.3%). This work provides a promising way to develop cCOF-based nanochannel enantioselective sensor.
研究领域:
材料科学
·
分析化学
·
生物传感
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Huiping Yang,Yinning Lin,Qian Mo,Zhaoquan Li,Fan Yang,Xinchun Li
Enzyme-mediating biotransformations commonly occur in micro- and nanospace, which is crucial to maintain the essential biochemical processes and physiological functions in living systems. Probing enzyme-catalytic reactions in a biomimetic fashion remains challenging due to the lack of competent tools and methodology. Here, we show that studying enzymatic reaction kinetics can be readily achieved by a well-designed solid-state nanopore. Using tyrosine as a classical substrate, we quantitatively characterize the catalytic activity of tyrosinase (TYR) and tyrosine decarboxylase (TDC) in a nanoconfined space. Tyrosine was first immobilized in the nanopipette, wherein the active sites of tyrosine were left unoccupied. When successively exposed to TYR and TDC, a two-step cascade reaction can spontaneously take place. In this process, the surface wettability and charge of the nanopipette stemming from the catalytic products can sensitively regulate ion transport and ionic current rectification behavior, which were monitored by ionic current signal. In this biomimetic scenario, we obtained the enzymatic reaction kinetics of monophenyl oxidase that were not previously actualized in the conventional macroenvironment. Significantly, TYR showed higher enzyme activity, with a Km value of 1.59 mM, which was lower than that measured in a free and open space (with a Km of 3.01 mM). This suggests that tyrosine should be the most appropriate substrate of TYR, thus improving our understanding of tyrosine-associated biochemical reactions. This work offers an applicable technical platform to mimic enzyme-mediated biotransformations and biometabolisms.
研究领域:
生物技术
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生物化学
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纳米技术
·
酶学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2019
·Vol. 15
·期 52
·1905451
·
IF 10.856
Lijun Ji,Mindong Gong,Tong Xu,Jun Gu,Xu Jiang,Taotao Liang,Yu Chen,Qingren Liu
The interactions of ions and molecules with material surface are highly dependent on the surface properties of the material. Therefore, the distribution of ions or molecules near the material surface may be affected by the surface properties. This phenomenon can be significant enough for controlling the structure of a material synthesized in the sub-micrometer scale confinement space of a template. This work confirms that inverse opals are perfect templates for offering confinement space, while their different surface properties can strongly affect ion and block copolymer distribution in the confinement space. This surface effect principle can be used for the controlled synthesis of colloids with complex composition. As an example, four kinds of mesoporous magnetic bioactive glass colloids with ordered mesopores, core–shell structure, open surface pores, or disordered mesopores are prepared by using polystyrene and carbon inverse opal templates. This work reveals that inverse opal templates possess great advantage in controlled synthesizing colloidal structures due to their surface effect on ions and molecules and confinement space.
研究领域:
生物材料学
·
纳米医学
·
组织工程
·
药物递送
·
生物矿化
·
胶体化学
✓ 已验证
DOI
高影响因子
Small
·
2017
·Vol. 13
·期 44
·1702011
·
IF 8.643
Chan Cao,Jie Yu,Meng-Yin Li,Ya-Qian Wang,He Tian,Yi-Tao Long
Direct, low-cost, label-free, and enzyme-free identification of single nucleobase is a great challenge for genomic studies. Here, this study reports that wild-type aerolysin can directly identify the difference of four types of single nucleobase (adenine, thymine, cytosine, and guanine) in a free DNA oligomer while avoiding the operations of additional DNA immobilization, adapter incorporation, and the use of the processing enzyme. The nanoconfined space of aerolysin enables DNA molecules to be limited in the narrow pore. Moreover, aerolysin exhibits an unexpected capability of detecting DNA oligomers at the femtomolar concentration. In the future, by virtue of the high sensitivity of aerolysin and its high capture ability for DNA oligomers, aerolysin will play an important role in the studies of single nucleobase variations and open up new avenues for a broad range of nucleic-acid-based sensing and disease diagnosis.
研究领域:
分子生物学
·
基因组学
·
生物传感
·
纳米孔技术
·
精准医学
·
核酸检测
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2015
·
IF 4.772
Xianying Zheng,Jixi Zhang,Jie Wang,Xueqiang Qi,Jessica M. Rosenholm,Kaiyong Cai
A composite nanocarrier system integrating the porous structure of mesoporous silica nanoparticles (MSNs) and the adhesive property of polydopamine (PDA) for loading and release of hydrophilic drugs is reported. Amino group functionalization facilitates the oxidant-induced surface polymerization of dopamine in the confined space of mesopores by Schiff base/Michael addition reaction in a mild synthesis. As a consequence, MSN@PDA particles have an average pore size of 4.0 nm, a particle diameter of ∼70 nm, as well as a thin layer of polydopamine coating on the surfaces of MSNs. The MSN@PDA nanocarriers can effectively adsorb hydrophilic drugs with high loading capacities (380 μg/mg for doxorubicin hydrochloride (DOX) and 320 μg/mg for calcein), facilitated by the π–π stacking interactions between the abundant aromatic rings of PDA and the aromatic backbones of drugs. Interestingly, sustained and pH-dependent drug release was observed for these drug-loaded MSN@PDA particles, owing to the adhesive property of polydopamine like “molecular glue”. Moreover, a catechol–metal–drug coordination system can be easily constructed on the basis of the coordination bonding between catechols in polydopamine and transition metal ions (Fe3+, Zn2+) as well as that between metal ions and anthracycline drugs (i.e., DOX), resulting in an acid-triggered drug release.
研究领域:
药剂学
·
纳米医学
·
生物材料
·
药物递送系统
·
肿瘤治疗
·
分子影像
·
化学生物学
✓ 已验证
DOI
高影响因子
Science Advances
·
2017
·Vol. 3
·期 5
·
IF 0
Jiancong Liu,Ning Wang,Yue Yu,Yan Yan,Hongyue Zhang,Jiyang Li,Jihong Yu
Thermally activated delayed fluorescence (TADF) materials are inspiring intensive research in optoelectronic applications. To date, most of the TADF materials are limited to metal-organic complexes and organic molecules with lifetimes of several microseconds/milliseconds that are sensitive to oxygen. We report a facial and general “dots-in-zeolites” strategy to in situ confine carbon dots (CDs) in zeolitic matrices during hydrothermal/solvothermal crystallization to generate high-efficient TADF materials with ultralong lifetimes. The resultant CDs@zeolite composites exhibit high quantum yields up to 52.14% and ultralong lifetimes up to 350 ms at ambient temperature and atmosphere. This intriguing TADF phenomenon is due to the fact that nanoconfined space of zeolites can efficiently stabilize the triplet states of CDs, thus enabling the reverse intersystem crossing process for TADF. Meanwhile, zeolite frameworks can also hinder oxygen quenching to present TADF behavior at air atmosphere. This design concept introduces a new perspective to develop materials with unique TADF performance and various novel delayed fluorescence–based applications.
研究领域:
材料科学
·
光电子学
·
纳米技术
·
荧光材料
·
无机化学
✓ 已验证
DOI
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Danqing Shen,Yulin Song,Xuping Chen,Yongquan Zhou,Hao Li,Jianming Pan
The fluoride pollution in environmental water can cause serious health problems, and the fluoride removal by sorbent is an effective strategy, and challenges by its poor selectivity and low capacity. Herein, we reported a new insight into the fabricating ultrafine zirconium oxide (ZrO 2 ) based composite sorbents (E-ELP-Zr) in “soft confined space” and efficient fluoride removal from water. It relies on the confined aqueous phase of Oil-in-Water (O/W) high internal phase emulsions (HIPEs) as droplet reactor, and ultrafine ZrO 2 particles (<10 nm) were achieved via the controllable in situ growth onto lipase immobilized poly(styrene-co-glycidyl methacrylate) nanospheres. E-ELP-Zr exhibited outstanding capacity for defluorination (135.8 mg g −1 at 298 K), quick adsorption rate in the first 10 min, and the superior selectivity against co-occurring anions (Cl - , SO 4 2− , NO 3 – and CO 3 2– ). The adsorption mechanism of fluoride on E-ELP-Zr was strong electrostatic attraction as well as the specific affinity of zirconium. After five regeneration cycles, the adsorption capacity of E-ELP-Zr slightly decreases to 88.55% of the initial value, and the excellent interfacial stability was benefited from covalently attached lipases. More importantly, this hybrid sorbent can be successfully applied for low level (7.15 mg L -1 ) of fluoride decontamination from actual sample of fluorinated wastewater, which endowed a distribution coefficient ( K d ) as high as 6.3 L g −1 .
研究领域:
环境科学
·
材料科学
·
化学工程
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）