Peng Yang,Zhaoqi Liu,Siyao Qin,Jun Hu,Songmei Yuan,Zhong Lin Wang,Xiangyu Chen
Tissue imaging is usually captured by hospital-based nuclear magnetic resonance. Here, we present a wearable triboelectric impedance tomography (TIT) system for noninvasive imaging of various biological tissues. The imaging mechanism relies on the obtained impedance information from the different soft human tissues. A high-precision signal source is designed on the basis of a composite triboelectric nanogenerator, which exhibits a minimal total harmonic distortion of 0.03% and a peak output signal-to-noise ratio up to 120 decibels. The current density injected into human skin is around 79.58 milliamperes per square meter, far below the safety threshold for medical devices. The TIT system achieves time-resolved tomography of human limbs’ soft tissues, and many appealing functions can be realized by using this wearable system, including the observation of muscle movement, the motion intention recognition, and the identification of pathological changes of soft tissue. Hence, this TIT system with excellent biocompatibility can be integrated with various devices, such as medical-assistive exoskeletons and smart protective suit.
Acupuncture, as an effective external treatment method, has been widely used in various clinical diseases, but the research on its mechanism still needs to be further deepened. Functional near-infrared spectroscopy (fNIRS) technology, as an emerging non-invasive neuroimaging technique, has the advantages of high timeliness, wide application scenarios, good portability and low cost. Currently, it is widely used in the mechanism research of acupuncture. This paper reviewed all the studies on the application of fNIRS in acupuncture, analyzed and summarized the current application status of fNIRS technology in acupuncture research. Firstly, we elaborated on the working principle of fNIRS and highlighted its advantages in acupuncture research and application. Secondly, we detailed the specific applications of fNIRS in acupuncture research. Finally, we discussed the existing problems of fNIRS in acupuncture research at present and the improvement directions for future research.
Yingli Wang,Xiao Wu,Yun Liu,Jincheng Zhang,Lei Wang,Xiliang Luo
Wearable systems for health monitoring are highly desired in personal diagnostics and precision medicine while challenges remain in constructing such wearable systems with reliability and high performance. Herein, we report a wearable platform for non-invasive monitoring biomarkers in sweat. The device is composed of a butterfly-shaped like microfluidic platform in which responsive photonic crystal hydrogels are embedded in each butterfly wing as sensors. Sweat lactate concentration and pH can be obtained via the color variation of the sensor with naked eyes. Accurate quantitative analysis of the two target analytes can be obtained via the image analysis on a mobile phone by integrating the linear range response to analytes within the physiological range. Moreover, the sensor exhibits good reproducibility, excellent selectivity and long-term stability. On-body trials have been conducted by attaching the device on volunteers’ body, and the obtained results are consistent with those analyzed through standardized methods, demonstrating its potentiality in real-time and continuous monitoring sweat biomarkers. This non-invasive wearable sensor provides a new strategy for personal health monitoring and sports performance assessment.
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