MOLECULES
·
2024
·Vol. 29
·期 16
·3799
·
IF 4.2
Yuying Zhang,Xiaoyu Wang,Dejun Zhou
Allergies are one of the diseases whose incidence rates have increased in recent years due to the greenhouse effect and extreme climate change. Therefore, the development of new antiallergic drugs has attracted the interest of researchers in chemistry and pharmacy fields. Dicoumarin is a coumarin derivative with various biological activities, but its antiallergic activity has not been evaluated. In this study, 14 different dicoumarin derivatives were synthesized by diethylamine-catalyzed condensation reactions of 4-hydroxycoumarin with 14 different aldehydes, and they were identified on the basis of their spectral data. The dicoumarin derivatives were subjected to studies on the degranulation of rat basophilic leukemia cells (RBL-2H3 cells) and mouse bone-marrow-derived mast cells (mBMMCs), and some of them showed good inhibitory effects on the degranulation of the two types of mast cells, demonstrating their good antiallergic activity. This study presents a new method of developing new antiallergic drugs.
研究领域:
药理学
·
有机化学
✓ 已验证
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2018
·Vol. 316
·期 1
·49-59
·
IF 1.181
Ji Guojia,Zhu Guiru,Wang Xingjun,Wei Yulin,Wu Hui,Yuan Junsheng,Gao Congjie
In order to reduce the loss of particles during the cycling operation, a technology for the granulation of short channel SBA-15 adsorbent was developed. The adsorption behavior of obtained granules was studied under various factors including initial pH value, contact time in different initial concentration and acid stability by batch experiments. A continuous packed column loaded with granules was performed to remove U(VI) from aqueous solution. The uranium concentration was highly enriched than feed solution. The granules packed in column exhibited excellent reusability through cycling test. The result showed promising application prospect in the uranium extraction from aqueous solution.
研究领域:
材料科学
·
环境科学
·
核化学
✓ 已验证
产品关联
DOI
高影响因子
Water
·
2024
·Vol. 16
·期 12
·1690
·
IF 3
Jingjing Yang,Jie Zhang,Jintong Liu,Quanxin Yang,Bingdang Wu,Xiaoyi Xu,Tianyin Huang
In order to recover the antimony from wastewater, a custom-designed fluidized-bed reactor (FBR) was employed to treat antimony-containing wastewater. By single-factor experiments, the effects of the solution pH, the molar ratio of [TA]/[Sb3+], the seed size and dosage, the up-flow velocity (U), and the hydraulic retention time (HRT) on antimony recovery were investigated based on the antimony removal and granulation efficiency. The optimum conditions for antimony recovery were obtained at pH 9.0, the molar ratio of [TA]/[Sb3+] of 2, 6 g/L of 13–38 μm Sb2O3as the fluidized seed, and the U and HRT of 42 m/h and 40 min, respectively; the antimony removal and granulation efficiency reached 95% and 91%, respectively. The granular products were analyzed by an X-ray polycrystalline diffractometer (XRD) and scanning electron microscopy (SEM) as cubic Sb2O3, widely used in various industries. The fluidized-bed reactor was operated continuously for 7 days, during which the antimony removal and granulation efficiency were stable at 96% and 93%, respectively. This study demonstrated the feasibility of the fluidized-bed granulation process for the recovery of antimony from wastewater. It provides a novel approach for retrieving and managing antimony-containing wastewater.
研究领域:
环境工程
·
材料科学
✓ 已验证
DOI
高影响因子
Bioresource Technology Reports
·
2019
·
IF 0
Fansheng Meng,Dongfang Liu,Wenli Huang,Zhongfang Lei,Zhenya Zhang
The effects of salinity (0–3%) on algal-bacterial granulation, nutrients removal and lipid production were studied in four identical sequencing batch reactors . Results demonstrated that high salinity (1–3%) enhanced biomass growth and granular settleability with little impact on organics removal and a slightly lower total P removal (57%) obtained. On the other hand, the activity of nitrifying bacteria was found to decrease with the increase of salinity, which was completely inhibited at the salinity of 3%, resulting in nitrite accumulation. No obvious change in lipid content was detected under the tested salinity levels, while its productivity was significantly increased under higher salinity conditions. The dominant lipid component, hexadecenoic acid at the salinity of 0%, shifted to oleic acid when the salinity was increased from 0% to 3%. In addition, high salinity favored the enrichment of Nitzschia rather than Stigeoclonium .
研究领域:
环境科学
·
微生物学
·
生物技术
✓ 已验证
DOI
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Guo-Wen Fang,Zhang-Min Li,Jian-Fei Li,Dan-Dan Cai,Yu-Jie Xiong,Yan Zhou,Wei Hui,Duan-Jian Tao
Lignin is the largest natural reservoir of aromatic compounds while its intricate polymeric structure complicates the reuse of lignin-derived waste. Herein, we report the development of lignin-based NH 3 adsorbents by upcycling sodium lignosulfonate (SLS) from spent paper pulp liquor. The demethylation of SLS was carried out to obtain the demethylated SLS (DSLS) and subsequently the pelletized DSLS@binder adsorbents were prepared using DSLS and three binders. The results indicate that the optimized 95% DSLS@PVA pellets with binder dosage of 5 wt% PVA (polyvinyl alcohol, PVA) exhibit the NH 3 adsorption capacity of 11.5 mmol g −1 , along with remarkable selectivity uptake for NH 3 /N 2 (3573) and NH 3 /CO 2 (1380). Moreover, the 95% DSLS@PVA pellets demonstrate ultra-fast adsorption kinetics (half-capacity uptake time of merely 38 s). Column breakthrough tests showed that the 95% DSLS@PVA pellets achieved NH 3 retention time of 370 min g −1 in a ternary gas mixture of NH 3 /N 2 /CO 2 (1 %/98 %/1%), with a dynamic adsorption capacity of 2.07 mmol g −1 . In addition, the 95% DSLS@PVA has a good balance between mechanical strength and NH 3 uptake cycle performance. This work provides a sustainable strategy for valorizing lignin waste into high-performance NH 3 adsorbents.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2025
·
IF 8.4
Lianjie Wang,Siyi Jing,Jie Gao,Pengcheng Xia,Tongtong Dou,Weiwei Wang,Ming Zhang,Weichuan Qiao
The addition of exogenous quorum sensing signaling molecules to the activated sludge system enables rapid sludge granulation. However, signaling molecules exposed to the environment are easily degraded, and their quorum sensing effects cannot be maintained in the long term. Therefore, they must be frequently added, which leads to an increase in operational costs. In this study, signaling molecules, acylated homoserine lactones (AHLs), were packaged into biomimetic bacterial extracellular vesicles—lipid vesicles (AHLs@ZZT), and the mediating role of lipid vesicles for AHLs was utilized to improve the utilization efficiency of signaling molecules. The results show that packaging of AHLs into vesicles slowed down the release of AHLs and protected them from degradation by porcine renal acylase. Moreover, the chemical properties of lipid vesicles are similar to the structure of bacterial cell walls, making it easier for the packaged AHLs to bind to target bacteria, thereby generating more EPS and accelerating the aggregation of microorganisms. After adding the lipid vesicles loaded with AHLs into the activated sludge system, the sludge granulation process was accelerated. Furthermore, the frequency of AHLs@ZZT addition was reduced by three times compared to that of unpackaged AHLs, resulting in a granular sludge with a smoother and denser surface. High-throughput sequencing of the sludge genome in the system indicated that adding AHLs@ZZT could promote microbial diversity and enrich functional microorganisms. Three-dimensional fluorescence spectra further revealed that the tryptophan and tyrosine proteins in extracellular polymeric substances secreted by these microorganisms facilitated sludge granulation. In summary, the lipid vesicle-mediated signaling molecular strategy can promote the rapid formation of granular sludge and maintain the long-term stability of the granular sludge structure, representing an economic and feasible regulation strategy.
研究领域:
环境生物学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENERGY
·
2022
·
IF 8.857
Yudong Ding,Lijiao Ma,Fengqi Zeng,Xingxing Zhao,Hong Wang,Xun Zhu,Qiang Liao
As a promising CO 2 adsorbent, Aluminum Fumarate (AlFu) metal organic frameworks (MOFs) were explored for pelletizing technology and CO 2 adsorption characteristics. The effects of binder type (sodium carboxymethylcellulose (CMC), aluminum sol (AS)) and content (2.5 wt%-20 wt%), CO 2 partial pressure (0.3 bar–1 bar) and temperature (35 °C–65 °C) on the mechanical performance and adsorption process were investigated. The results revealed that with the increase of binder mass, the pellet mechanical strength rose while the CO 2 adsorption amount decreased. The AlFu pellet with 2.5 wt% CMC could retain the powder porosity and adsorption capacity . The mechanical strength of AlFu@CMC-2.5 wt% achieved 1.486 MPa, and the maximum adsorption capacity was 1.26 mmol/g at 35 °C and 1.0 bar. The CO 2 adsorption capacity was increased with lower adsorption temperature and higher CO 2 partial pressure. Compared with pseudo second order model and pseudo first order kinetic model , Avrami kinetic model could better describe the CO 2 adsorption behavior of AlFu pellet. It indicated that the adsorption process was not a single physical or chemical adsorption . The rate-limiting kinetic analysis showed that the CO 2 adsorption rate was determined by film diffusion and intraparticle diffusion rather than inter-particle diffusion.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Qinglong Luo,Mingzhe Dong,Guoliang Nie,Zhong Liu,Zhijian Wu,Jun Li
Hierarchical meso- and macro-porosity increases the adsorption capacity of lithium adsorbents and the granulation of powder lithium adsorbents raises the applicability of lithium adsorbents. Granulated lithium adsorbents consisting of porous mixtures of Li-Al-LDHs (layered double hydroxide) and NH 4 Al 3 (SO 4 ) 2 (OH) 6 by crosslinking sodium alginate were successfully prepared, and adsorption-desorption performance of granulated adsorbents was evaluated. The adsorption capacity of granulated lithium adsorbents reached 9.66 mg/g (at the loading capacity of 83.3% by mass, 25 ℃, and pH=6). The granulated lithium adsorbents were prepared in three steps. First, porous precursors of NH 4 Al 3 (SO 4 ) 2 (OH) 6 and γ-AlOOH were synthesized hydrothermally using Al 2 (SO 4 ) 3 ·18H 2 O and Urea. The porous powder precursors were then lithiated in aqueous LiOH solution to give mixed porous powders of NH 4 Al 3 (SO 4 ) 2 (OH) 6 and Li-Al-LDHs of Li 2 Al 4 (OH) 12 SO 4 ·xH 2 O. Lithiated powder precursors were finally granulated by ionic crosslinking sodium alginate in CaCl 2 aqueous solutions and deintercalated using water. The precursors and lithiated precursors were characterized by IR spectroscopy , powder XRD , XPS spectroscopy , SEM, TEM, thermal analyses, particle size analysis , and BET surface area. The adsorption isotherm , adsorption kinetics , the effects of pH, temperature, initial lithium concentration, and the anions and cations interference on lithium adsorption-desorption performance of granulated lithium adsorbents were studied. The adsorption isotherm and adsorption kinetics were best fitted with the Langmuir model and pseudo-second-order rate equation , respectively. Lithium adsorption was an endothermic process. The granulated lithium adsorbents were applied to real East Taigener salt lake brine. The lithium adsorption capacity dropped slightly to 9.16 mg/g; the adsorption equilibrium reached within 180 min; the dissolution rate was 0.54% after 10 cycles of adsorption and desorption. The granulated lithium adsorbents prepared show the potential in industrial application.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Pu Huang,Xinzheng Wei,Xinmei Wang,Zhengjun Gu,Yafei Guo,Chuanwen Zhao
Amine-based adsorbents show promise for removing low-concentration CO 2 from environmental control and life support systems (ECLSSs), while the powder adsorbents are facing the challenges of reaction non-uniformity, pressure drop and material elutriation. To solve the problems, amine-based adsorbent pellets are fabricated by the extrusion–spheronization (ES), agar-assisted moulding (AM) and graphite-casting (GC) methods. The adsorbent pellets are further modified with pore-forming template for improved CO 2 adsorption performance. The influences of granulation and pore-forming template modification on the structure-performance relationships of the adsorbent pellets are investigated. Granulation exerts adverse effect on the pore structure of tetraethylenepentamine supported on silica gel (TEPA-SG) adsorbent, which is not conducive to the bulk diffusion of CO 2 , and the CO 2 adsorption capacity and kinetics thus have been impaired. The TEPA-SG-ES adsorbent pellets prepared by the extrusion–spheronization method show a relatively higher CO 2 capture capacity of 1.01 mmol CO 2 /g due to better textural parameters and uniform dispersion of amine species. Thanks to the extrusion process, the adsorbent pellets also exhibit good mechanical properties with a high compressive strength of 10.90 MPa and low abrasion index of 0.36%. Both the textural properties and CO 2 uptakes of the pellets can be restored upon template modification, and the promoting effect depends on the different templates employed due to their distinct pyrolysis rates and pathways. Mechanical properties will be adversely affected by the doped pore-forming template. The TEPA-SG-ES-UA pellets prepared with urea modification exhibit a great CO 2 capture capacity of 1.48 mmol CO 2 /g and good mechanical properties with a high compressive strength of 4.90 MPa and a low abrasion index of 0.87%, and it could be a nice adsorbent candidate for removing low-concentration CO 2 from ECLSSs.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Shuangchun Jiang,He Tao,Yingjuan Shao,Yao Fu,Wenqi Zhong
The pressurization can significantly enhance the thermochemical energy storage performance of Ca-based materials. In this study, detailed experimental investigations were conducted in both fixed bed and fluidized bed on the performance of TiO 2 modified Ca-based materials ranged from 700 °C to 900 °C under pressurized conditions (0.1 MPa to 0.8 MPa) from powder to pellet, including the influence of inert dopants on the properties of CaO powder, the optimization of biomass pore-former agents' selection and the enhancement of pressurized fluidization states on the performance of pelletized materials. The findings indicated that the pressure intensity has a positive correlation with the energy storage density and cyclic stability of TiO 2 modified Ca-based materials. The results demonstrated that the properties of CaO powder intensified with the pressure and the energy storage density was increased by 31.4 % with 5 % TiO 2 doped at 0.8 MPa. And the energy storage performance of the pelletized CaO-5TiO 2 with 10 % bagasse added was also significantly improved at a higher-pressure condition. The energy storage performance of the determined 10B-CaO-5TiO 2 pellet under fluidization conditions at 0.8 MPa was 38.9 % higher than that of atmospheric pressure after 10 cycles. As the carbonation pressure increased, the average grain size of CaO exhibited a decline of 7.0 %, a slighter sintering and deeper reaction region were observed into the determined pellet. Furthermore, the specific surface area and pore volumes of the 10B-CaO-5TiO 2 pellets under high carbonation pressure were 382.8 % and 460.0 % higher than that of atmospheric pressure in the fluidized bed, respectively.
研究领域:
材料科学
·
能源化学
·
化学工程
·
多相催化
·
储能技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2022
·
IF 14.224
Mingyan Zhao,Jingfeng Gao,Haoran Zhang,Yingchao Cui,Zhiqi Wang,Yifan Zhao,Yi Zhang,Ying Liu
Surfactants could influence sludge morphology and disinfectants were linked to antibiotic resistance genes (ARGs). Thus, the response of activated sludge and ARGs to long-term quaternary ammonium compounds (QACs) exposure required further investigation, which is a popular surfactant and disinfectant. Here, three sequencing batch reactors were fed with 5 mg/L most frequently detected QACs (dodecyl trimethyl ammonium chloride (ATMAC C12), dodecyl benzyl dimethyl ammonium chloride (BAC C12) and didodecyl dimethyl ammonium chloride (DADMAC C12)) for 180 d. The long-term inhibitory effect on denitrification ranked: DADMAC C12 > BAC C12 > ATMAC C12. Besides, obvious granular sludge promoted by the increase of α-Helix/(β-Sheet + Random coil) appeared in DADMAC C12 system. Moreover, intracellular ARGs increased when denitrification systems encountered QACs acutely but decreased in systems chronically exposed to QACs. Although replication and repair metabolism in ATMAC C12 system was higher, ATMAC C12 significantly promoted proliferation of extracellular ARGs. It was noteworthy that the propagation risk of extracellular ARGs in sludge increased significantly during sludge granulation process, and intracellular sul2 genes in sludge and water both increased with the granular diameter in DADMAC C12 system. The universal utilization of QACs may enhance antibiotic resistance of bacteria in wastewater treatment plants , deserving more attention.
研究领域:
环境科学
·
微生物学
·
水处理工程
✓ 已验证
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Dan Li,Su Yan,Xiaoyu Yong,Xueying Zhang,Jun Zhou
Coal chemical wastewater (CCW) containing toxic and hazardous matters requires to be treated prior to discharge. Promoting the in-situ formation of magnetic aerobic granular sludge (mAGS) in continuous flow reactor process has a great potential for CCW remediation. However, long granulation time and low stability limit the application of AGS technology. In this study, Fe 3 O 4 /sludge biochar (Fe 3 O 4 /SC) with biochar matrix derived from coal chemical sludge were applied to facilitate the aerobic granulation in two-stage continuous flow reactors, containing separated anoxic and oxic reaction units (abbreviated as A/O process). The performance of A/O process was evaluated at various hydraulic retention times (HRTs) (42 h, 27 h, and 15 h). Magnetic Fe 3 O 4 /SC with porous structures, high specific surface area (BET = 96.69 m 2 /g), and abundant functional groups was successfully prepared by ball-milled method. Adding magnetic Fe 3 O 4 /SC to A/O process could promote aerobic granulation (85 days) and the removal of chemical oxygen demand (COD), ammonia nitrogen (NH 4 + -N) , and total nitrogen (TN) from CCW at all tested HRTs. Since the formed mAGS had high biomass, good settling ability, and high electrochemical activities, mAGS-based A/O process had high tolerance to the decrease of HRT from 42 h to 15 h for CCW treatment. The optimized HRT for A/O process was 27 h, at which Fe 3 O 4 /SC addition can result in the increase of COD, NH 4 + -N and TN removal efficiencies by 2.5 %, 4.7 % and 10.5 %, respectively. Based on 16S rRNA genes sequencing, the relative abundances of genus Nitrosomonas , Hyphomicrobium / Hydrogenophaga and Gaiella in mAGS accounting for nitrification, denitrification as well as COD removal were increased during aerobic granulation. Overall, this study proved that adding Fe 3 O 4 /SC to A/O process was effective for facilitating aerobic granulation and CCW treatment.
研究领域:
环境工程
·
污水处理
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）