SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Xin Xu,Danyang Nan,Huan Yang,Shuang Pan,Hui Liu,Xiaoli Hu
Quercetin is a nature polyphenolic flavonoid compound, which act as antioxidant and radical scavengers in cells. However, such activities strongly depend on the intracellular microenvironment, which has become an urgency to develop a more stable method for better use of quercetin. Herein, we report a facile approach to fabricate Quercetin@ZIF-90 (QZ) with a narrow size distribution about 100 nm, the synthesized QZ exhibits considerable antioxidant and radical scavenger ability comparing to bare quercetin. Moreover, the experiment results indicated that QZ was sensitive to adenosine 5′-triphosphate (ATP) and pH, thus QZ was applied as a novel antioxidant for the determination of ATP. In brief, though 3, 3′, 5, 5′-tetramethylbenzidine (TMB) could be oxidized to blue cation radical complex by oxidase-like BSA-MnO 2 nanosheets (MNs) at neutral pH, QZ could sufficiently protect against MNs-induced TMB cation radicals reaction, which means no obvious color change in MNs-TMB system after the addition of QZ. However, ATP could induced collapse of QZ due to the interaction between ATP and Zn 2+ allowing the release of quercetin from ZIF-90 shell, and the inhibition effect to the MNs was weakened, leading to the recovery of blue oxTMB. In this way, a novel “Off-On” colorimetric method for ATP sensing was established, and the method displayed a good linear relationship ranging from 2.0 μ mol L −1 to 80.0 μ mol L −1 . The reported strategy is also capable of ATP sensing in MCF-7 cell lysates, which illustrated our method exhibited high sensitivity and selectivity.
研究领域:
生物化学
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
DYES AND PIGMENTS
·
2014
·
IF 3.468
Hong-mei Nie,Cheng-bin Gong,Qian Tang,Xue-bing Ma,Cheuk-fai Chow
A novel colorimetric chemodosimeter for cyanide (CN − ) and 1-allyl-4-[2-(4-hydroxyphenyl)ethenyl)]-quinolinium bromide (AHPEQB) was designed and synthesized by condensation and terminal N alkyl reaction. AHPEQB exhibited highly selective and sensitive recognition properties toward CN − over other competing anions in ethanol, a protic solvent, with a 1:1 binding stoichiometry and a detection limit of 1.7 × 10 −6 mol L −1 . AHPEQB also displayed rapid colorimetric response that could be readily observed by the naked eye and good reversibility . The sensing mechanism of the proposed chemodosimeter was studied by UV–Vis, 1 H NMR titration, and comparison 1-allyl-4-[2-(4-acetoxyphenyl)ethenyl)]-quinolinium bromide (AAPEQB). The colorimetric chemodosimeter showed high accuracy in determining the concentration of CN − in real water samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2020
·Vol. 12
·期 14
·1919-1925
·
IF 2.596
Yuan Qu,Heng Qian,Yiduo Mi,Jingjing He,Haixiang Gao,Runhua Lu,Sanbing Zhang,Wenfeng Zhou
A new, simple colorimetric aptasensor based on the aggregation-induced color change of citrate-stabilized AuNPs was designed for the specific and sensitive determination of ametryn. Citrate-stabilized AuNPs with negative surface charges were synthesized via an easy one-pot reaction. Because of the electrostatic interaction between the three-nitrogen hybrid ring of ametryn and gold nanoparticles, the citrate-stabilized AuNPs easily undergo aggregation in the presence of ametryn. Thus, with a color change from wine red to gray, ametryn was visually detected by a colorimetric aptasensor. In addition, the detection result can also be measured quantitatively using a UV-vis spectrophotometer. The aptasensor has good selectivity and sensitivity to ametryn in the linear range of 0–80.0 μg L−1. According to the IUPAC criteria (3σ rule), the detection limit of ametryn is 0.15 μg L−1. Moreover, the aptasensor was successfully applied to the detection of ametryn in Yongding River from Zhaocun, Yizhuang Jingkai Sewage Treatment Plant and Yizhuang Nokia Factory water samples. The recovery reached 98.9–101.6%, 95.7–101.3% and 100.0–103.3%, respectively. The excellent performance of the colorimetric aptasensor in the detection of ametryn indicates its potential applications in the detection of ametryn in more complex environmental samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2019
·
IF 6.35
Xinfeng Zhang,Xiaoya Fan,Yanying Wang,Fengjie Lei,Lin Li,Juewen Liu,Peng Wu
Aggregation of plasmonic gold nanoparticles (AuNPs) has been widely used for label-free colorimetric sensing. Adding salt is a commonly used method to induce a color change, but salt-induced aggregation by charge screening is a slow kinetic process, making quantitative and reproducible measurement difficult. Herein, we explored an alternative method by charge neutralization using positively charged molecules, such as a DNA-staining dye, SYBR Green I (SG), for efficient and stable assembly of AuNPs. Even submicromolar SG effectively triggered the aggregation of AuNPs in less than 1 min, and the resulting intense blue color was stable for over 10 h. The charge neutralization effect of SG was confirmed with zeta potential measurements. Besides, pH-dependent aggregation of AuNPs by SG agreed well with the pKa of the nitrogen atoms responsible for the positive charges in the SG structure. Moreover, the charge neutralization effect was also observed from polycations such as polyamines. The SG-induced assembly of AuNPs was developed into a label-free colorimetric sensing platform. Benefiting from the intense blue color, this new sensing strategy allowed visual detection of as low as 0.1 nM DNA, 50-fold lower than that by salt. Such a charge neutralization strategy may inspire further thinking on fundamental colloidal science and its applications in analytical chemistry. This work itself significantly improved AuNP-based colorimetric sensors in terms of detection time, signal stability, and sensitivity.
研究领域:
分析化学
·
胶体科学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2018
·Vol. 10
·期 47
·5679-5686
·
IF 2.073
Jia Zheng,Ping Yang,Jiawei Li,Pan Li,Jingzhou Hou,Danqun Huo,Changjun Hou,Suyi Zhang
In the present study, we fabricated a 3 × 3 colorimetric sensor array using nanomaterials/dyes as sensing dots to discriminate 8 commercial baijiu samples. Sensing dots can cross-respond to baijiu samples, enabling color changes of the sensor array and subsequently providing special fingerprints. Eight baijiu samples were successfully discriminated using principal component analysis (PCA), linear discriminant analysis (LDA) and hierarchical cluster analysis (HCA) without misclassification. A radial basis function neural network (RBFN) was employed to determine the fitting relationship between the predicted samples and the actual samples. From all the evidence, we draw the conclusion that this 3 × 3 NP-dye colorimetric discrimination system can perform successful distinction of baijiu. Moreover, a separation tendency of different baijiu samples was shown via alcoholic-strength (38° and 52°) without detection of alcoholic-strength. This effort may benefit quality control of baijiu in the market and in mass-production in the factory.
研究领域:
分析化学
·
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 71
·66963-66970
·
IF 3.289
Haiguan Yang,Junqi Zha,Peng Zhang,Yuhao Xiong,Linjing Su,Fanggui Ye
CoS, which was prepared using a facile solvothermal method, and characterized using various analytical techniques, was demonstrated for the first time to exhibit intrinsic peroxidase-like activity. CoS catalyzed the oxidation of the peroxidase substrate 3,3′,5,5′-tetramethylbenzidine in the presence of H2O2 rendering the reaction solution blue, which is the principle used for H2O2 sensing. The mechanism of the CoS catalysis was also investigated. Under optimal conditions, the linearity of H2O2 detection ranged from 0.05 to 0.8 mM (R2 = 0.9965). More importantly, using the reducibility of glutathione and the strong affinity to thiol compounds exhibited by mercury ions (Hg2+), a novel “off–on” colorimetric sensor for Hg2+ determination was designed using CoS as a peroxidase mimics. The analytical platform for Hg2+ determination was developed, ranging from 0.25 to 3 μM (R2 = 0.9965). The limit of detection was 0.1 μM. CoS exhibited several advantageous features including good chemical stability, ease of preparation, simple purification, and excellent reproducibility.
研究领域:
生物化学
·
分析化学
·
材料科学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Guangzhi Wang,Yuchen Guo,Yang Yu,Yan Shi,Yuxiang Ying,Hong Men
Pork freshness is crucial for flavour, nutrition and consumer health. The current colorimetric sensor array (CSA) detection systems face challenges related to high sensor development costs, low recognition accuracy and limitations in the platform use. Herein, we developed a CSA and ColorNet framework to detect pork freshness. The 53-point CSA was designed by selecting sensitised pH indicators and aldehyde/ketone indicators. To optimize the sensor, the Euclidean distance method was used to identify 24 array points with dyes that exhibited more sensitive responses. The ColorNet captured the color information of pork freshness, allowing real-time detection with a 99.5 % accuracy. For practical deployment and mobile applications, a refined 12-point CSA was developed using gradient activation mapping, maintaining a 99 % recognition rate, which is comparable with the 24-point CSA. The proposed CSA and model ensure consumer health and safety, providing strong technical support for quality monitoring and control in the pork industry.
研究领域:
食品科学
·
人工智能
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Hang Ren,Qianqian Zhang,Zhao Meng,Rui Ling,Weidong Qin,Zhenglong Wu
Gold triangular nanoplates (AuTNPs) and gold nanorods (AuNRs) have been widely used in colorimetric sensing due to their shape-dependent localized surface plasmon resonance properties. Herein, we report new colorimetric detection strategies based on a low-cost RGB colorimetry system equipped with an industrial-grade color sensor and provide two demonstrations for the potential applications. The first is the online detection of cadmium ions (Cd2+) through the Cd2+-promoted etching of glutathione-stabilized AuTNPs that was initialized by H2O2 and iodide. For the first time, the etching time corresponding to the inflection point of the first derivative of the Red channel transmission curve was used for calibration. The method was finally applied in the detection of Cd2+ in fortified rice samples. In the second demonstration, the RGB values continuously acquired using the instrument were converted to HSV (hue, saturation, and value) space, which was successfully employed in pH detection via etching of AuNRs. Importantly, the overaged AuNRs with poor homogeneity could be discerned by the method at the beginning of analysis, which is helpful in achieving reliable measurements. Our results suggest that integration of the low-cost portable instrument and the new strategies has the promising potential for sensitive, accurate, precise, and good-linearity detection.
研究领域:
分析化学
·
纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2019
·
IF 2.433
Lixia Liu,Xuefang Shang,Ruiqi He,Jie Li,Yanmei Chen,Hongli Chen,Tianyun Wang
A zinc(II) complex–based selective colorimetric chemosensor for H 2 S was synthesized. The ligand and complex crystals were obtained, and the molecular structures were confirmed by single-crystal X-ray diffraction analysis in addition to electrospray ionization high resolution mass spectrometer, as well as elemental analysis . The photo-physical and recognition properties toward HS – were examined. The complex indicated the presence of HS – with an obvious color change from yellow to red, based on zinc ion displacement mechanism. However no obvious changes were observed in the presence of other anions (AcO − , H 2 PO 4 − , F − , Cl − , Br − , I − and SO 3 2− ). In addition, the chemosensor was applied to assess HeLa cell cytotoxicity. Our inorganic-reaction based sensor for HS – is simple, easily prepared and efficient. The complex has many potential chemical and analytical applications for the sensing of H 2 S.
研究领域:
化学
·
生物学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2016
·
IF 4.035
Yan Zhang,Jingjing Jiang,Min Li,Pengfei Gao,Ying Zhou,Guomei Zhang,Shaomin Shuang,Chuan Dong
Herein, a novel, high sensitive, and specific colorimetric sensor for cysteine (Cys) based on pectinase protected gold nanoparticles (P@AuNPs) has been demonstrated for the first time. The P@AuNPs were synthesized by “MW-assisted heat method” and were characterized by UV–vis, TEM , FT-IR and zeta potential techniques. Cys could cause the aggregation of P@AuNPs due to formation of the strong covalent Au-S bond and electrostatic binding. As the Cys concentration increased, the color of the solutions gradually changed from wine-red to blue as well as the large absorption band shifted from 523 to 650 nm upon P@AuNPs aggregation. In addition, various experimental parameters such as pH, the amount of P@AuNPs and incubation time were investigated for the optimum sensing conditions. The concentration of Cys could be determined by monitoring with the naked eye or a UV–vis spectrometer. The proposed colorimetric sensor showed an extreme selectivity toward the determination of Cys in the presence of 20-fold all other different interferents. Under optimum conditions, this method exhibited two good linear ranges from 4.85×10 −9 to 3.02×10 −4 M (R 2 =0.996) and 3.25×10 −3 to 1.03 × 10 −2 M (R 2 =0.999), with a low detection limit of 4.6×10 −9 M. Moreover, this colorimetric sensor was successfully applied to the detection of Cys in human urine samples, demonstrating its great value for practical application in biological systems.
研究领域:
分析化学
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2016
·Vol. 9
·期 1
·141-148
·
IF 1.915
Li Jia-wei,Hou Chang-jun,Huo Dan-qun,Yang Mei,Zhang Su-yi,Ma Yi,Lin Yang
The components of Chinese liquor are influenced by geographical origins and raw materials. Currently, Chinese liquor identification systems are limited and have a single application that can distinguish only one nature of flavor type and production area. Four chemical reagents were successfully used to build this 3 × 1 simple colorimetric sensor array. This is the first time that a highly accurate colorimetric Chinese liquor sensor array was fabricated using only a few array points. It could distinguish four types of Chinese base liquors from Luzhou Laojiao, nine types of Chinese liquors with different flavor types, and seven types of Chinese liquors from different geographical origins. In order to ensure the accuracy, seven parallel samples were analyzed with water used as a control. PCA proved this sensor array to be effective. In LDA and HCA, every group was clearly classified. The “leave-one-out” cross-validation method was applied with 100% prediction ability in the three experiments. According to the results of the PCA, HCA, LDA, and the “leave-one-out” method, we can deduce that this colorimetric sensor array with multiple applications has great performance in discriminating Chinese liquors.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2017
·
IF 3.034
Xiaoliang Zeng,Yajun Zhang,Jinyi Zhang,Hao Hu,Xi Wu,Zhou Long,Xiandeng Hou
A new colorimetric sensor for Pb 2 + based on bimetallic (Eu-Tb) lanthanide (Ln) metal-organic frameworks (MOFs) was developed for field screen analysis of lead-polluted environmental water. The Ln-MOFs were prepared by using a simple and fast synthetic method, with Tb 3 + /Eu 3 + and 1,4-benzenedicarboxylate (BDC) as precursors. The color of the luminescent Ln-MOFs could be fine-tuned from green to red by doping the MOFs with different ratios of Tb 3 + /Eu 3 + , and a specific MOFs Tb 1.7 Eu 0.3 (BDC) 3 ·(H 2 O) 4 was synthesized and employed as the sensing probe. With the existence of Pb 2 + in an appropriate concentration range with a certain amount of Tb 1.7 Eu 0.3 (BDC) 3 ·(H 2 O) 4 , the emission color of the MOFs changed from red-orange to green, which could be visually observed by the naked eyes. This colorimetric sensing method turned out to be simple, rapid, cost-effective and highly selective, without any requirement for complicated instrumentation. Furthermore, lead-polluted environmental water samples were analyzed for Pb 2 + , illustrating the promising perspective of the developed method for field screen analysis.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）