ANALYST
·
2015
·Vol. 140
·期 15
·5251-5256
·
IF 4.107
Xiao-Qing Lin,Hao-Hua Deng,Gang-Wei Wu,Hua-Ping Peng,Ai-Lin Liu,Xin-Hua Lin,Xing-Hua Xia,Wei Chen
A facile approach is proposed for the growth of platinum nanoparticles on graphene oxide (PtNPs/GO). The resulting PtNPs/GO hybrid has been proved to function as peroxidase mimics that can catalyze the oxidation of peroxidase substrates in the presence of hydrogen peroxide (H2O2). Kinetic studies indicate that the PtNPs/GO nanocomposite has a considerably higher affinity for both 3,3′,5,5′-tetramethylbenzidine (TMB) and H2O2 than those of other platinum-based peroxidase mimics. Furthermore, colorimetric recognition and sensing of L-cysteine with high sensitivity and selectivity is presented based on target-induced shielding against the peroxidase-like activity of PtNPs/GO. We envision that this material will be an ideal candidate for a wide range of potential applications in the fields of biomedicine and environmental chemistry.
研究领域:
生物医学
·
环境化学
·
纳米材料科学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2020
·Vol. 8
·期 48
·17202-17210
·
IF 7.059
Xin Zhang,Yumei Ran,Qianqian Fu,Jianping Ge
Amorphous photonic crystals (APCs) assembled by mesoporous SiO2 particles were first used to develop thin layer chromatography (TLC) with high separation efficiency and convenient colorimetric recognition. The m-SiO2 APC film has a large number of micron-scale pores, which significantly accelerate the solvent diffusion and address the problem of the short-distance development. Meanwhile, the abundant mesopores in m-SiO2 particles intensify the adsorption–desorption between analytes and APC film. Although the critical micron-scale pores were introduced by the sacrifice of long-range ordered structure, the APC film still has uniform structural colors due to its short-range ordered structure. Therefore, the APC film retains the advantage of colorimetric recognition, where the loaded chemicals cause an increased refractive index and a structural-color change. Compared to traditional SiO2 gel TLC, the sample recognition in APC TLC was simplified because chemical compounds, which must be dyed, can be directly recognized now. Meanwhile, the separation resolution achieved by m-SiO2 APC TLC was also improved due to the enhancement of adsorption–desorption.
研究领域:
材料科学
·
分析化学
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产品关联
DOI
高影响因子
Advanced Science
·
2022
·Vol. 9
·期 22
·2202123
·
IF 17.521
Ying Li,Jiahui Wang,Qing Yang,Guozhen Shen
Optoelectronic synapses combining optical-sensing and synaptic functions are playing an increasingly vital role in the neuromorphic computing systems development, which can efficiently process visual information and complex recognition, memory, and learning. Metal halides are considered promising candidates for synaptic devices due to their excellent optoelectronic properties. However, the toxicity of lead and the further development of device functions are the recognized problems at present. Herein, a flexible optoelectronic synapses system based on high-quality lead-free Cs 3 Bi 2 I 9 nanocrystals is demonstrated, in which the carrier confinement caused by the band mismatching between the Cs 3 Bi 2 I 9 and the organic semiconductor layer provides the possibility to simulate synaptic behaviors. The synaptic functions including long/short-term memory and learning-forgetting-relearning are demonstrated in this device and visual perception, visual memory, and color recognition functions are successfully implemented. Additionally, the flexible device exhibits excellent robustness and can realize imaging of light distribution under curved hemispheres similar to the human eye. Finally, through the simulation based on an artificial neural network algorithm, the device successfully realizes the high-precision recognition of handwritten digital images and possesses a strong fault tolerant capability even in bending states. These results are expected to drive the practical progress of metal halide for neuromorphic computing.
研究领域:
材料科学
·
神经科学
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人工智能
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DOI
PubMed
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 5
·736
·
IF 5.719
Yarong Xue,Mingfen Wei,Dingyi Fu,Yuqing Wu,Bo Sun,Xianghui Yu,Lixin Wu
We report a unique phenomenon, the opposite color response of a giant polyoxometalate, (NH4)42[Mo132O372(CHCOO)30] (H2O)72([Mo132]), to the existing states of human papillomavirus (HPV) major capsid protein, L1-pentamer (L1-p), and virus-like particles (VLPs). The color responses originate from the different assembly forms between [Mo132] and the capsid protein. The latter were inspected and separated by using CsCl gradient centrifugation, and validated in detail by sodium dodecyl sulfate-polyacrylamide gel-electrophoresis (SDS-PAGE), dynamic light scattering (DLS), and transmission electron microscopy (TEM) imaging. Furthermore, the intrinsic mechanisms were investigated in-depth by using XPS-based semi-quantitative analysis and well-designed peptides, revealing the critical points of L1 that determine the charge–transfer ratio between Mo(V) to Mo(VI), and consequently, the levels of [Mo132] hypochromic in different assemblies. Such a unique phenomenon is significant as it supplies a colorimetry approach to distinguish the existing states of the HPV capsid protein and would be significant in the quality assay of the HPV vaccine and existing states of other viruses in the future.Keywords:colorimetric discrimination;giant polyoxometalate;HPV capsid protein;hypochromic of molybdate clusters;opposite color response
研究领域:
化学
·
病毒学
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材料科学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 11
·1-10
·
IF 6.408
Bu Yiming,Yin Ranhao,Yu Long,Su Pengchen,Li Zibiao,Ye Enyi,Loh Xian Jun,Zhu Houjuan,Wang Suhua
An enhanced ratiometric fluorescence sensor was built for on-site visual detection of doxycycline (DOX) through the interaction with bovine serum albumin on the surface of red emissive copper nanoclusters. Upon the addition of weakly fluorescent DOX, the red fluorescence from copper nanoclusters gradually decreased through the inner-filter effect (IFE), while a green fluorescence appears and significantly increases, forming an interesting fluorescent isosbestic point, which was assigned to DOX due to sensitization effect of bovine serum albumin. On the basis of this ratiometric fluorescence, the system possessed good limit of detection (LOD) of 45 nM and excellent selectivity for DOX over other tetracyclines. Based on these findings, a paper-based sensor has been fabricated for distinct visual detection of trace DOX and combined with smartphone color recognizer for quantitative detection of DOX (LOD = 83 nM). This method shows broad application prospects in environmental monitoring and food safety. Graphical abstract
研究领域:
分析化学
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环境科学
·
材料科学
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生物技术
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DOI
PubMed
高影响因子
MACROMOLECULAR RAPID COMMUNICATIONS
·
2025
·
IF 4.3
Rumeng Gao,Yayu Feng,Yunfei Liu,Lin Wang,Kuilin Deng
In this study, poly( 2, 4 -thiazolidinedione) (PTD) is prepared by oxidative polymerization using 2,4 -thiazolidinedione (TD) as monomer. PTD exhibits significant polymerization-induced emission (PIE) at 540 nm, resulting from the intramolecular aggregation of thiazole heterocycles and the formation of electron-space conjugation. The PIE-active PTD demonstrates simultaneously specific detection of Cu 2 ⁺/Co 2 ⁺ with detection limits as low as 0.47 µ M and 68.9 nM, respectively, even in the presence of 14 common metal ions and 11 anions. Fluorescence quenching experiments reveal that Cu 2 ⁺/Co 2 ⁺ coordinates with PTD to form a 1:2 non-fluorescent complex through a static quenching mode. Most importantly, the efficient differentiation between Cu 2 ⁺ and Co 2 ⁺ is achieved using dynamic color recognition technology based on smartphone APP and UV–vis absorption spectroscopy. This approach innovatively combines solution color gradient change with smartphone RGB to establish a semi-quantitative and convenient detection method. The lower detection limits of Cu 2 ⁺/Co 2 ⁺ reached 36.2 and 37.8 nM m with naked eye recognition, which provides a technological solution for the rapid detection of Cu 2 ⁺/Co 2 ⁺ ions without the aid of large-scale instruments. In brief, the successful preparation and detection application of PIE-active PTD open up a straightforward and feasible path for molecular design of fluorescent non-conjugated polymers from non-fluorescent monomers.
研究领域:
高分子化学
·
分析化学
·
荧光材料
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传感器与生物传感器
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环境监测
·
光学传感
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）