CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2022
·
IF 3.898
Zhaofeng Zhang,Juanjuan Ding,Min Wu,Bochao Liu,Huiwen Song,Shengping You,Wei Qi,Rongxin Su,Zhimin He
γ-Aminobutyric acid (GABA), a natural non-protein amino acid, plays an irreplaceable role in regulating the life activities of organisms. Nowadays, the separation and purification of food-grade GABA from fermentation broth is still a great challenge. This research utilized monosodium glutamate as a substrate for the production of high-purity GABA via an integrated process incorporating fermentation, purification, and crystallization. Firstly, 147 g·L −1 GABA with a yield of 99.8% was achieved through fed-batch fermentation by Lactobacillus brevis CE701. Secondly, three integrated purification methods by ethanol precipitation were compared, and crude GABA with a purity of 89.85% was obtained by the optimized method. Thirdly, GABA crystals with a purity of 98.69% and a yield of 60% were further obtained through a designed crystallization process. Furthermore, the GABA industrial production process model was established by Superproper Designer V10 software, and material balance and economic analysis were carried out. Ethanol used in the process was recovered with a recovery of 98.79% through Aspen simulated extractive distillation. Then the fixed investment (equipment purchase and installation costs) for an annual production of 80 t GABA will be about 833000 USD; the total annual production cost (raw material cost and utility cost) will be about 641000 USD. The annual sale of GABA may be at the range of 2400000–4000000 USD and the payback period will be about 1–2 year. This integrated process provides a potential way for the industrial-scale production of food-grade GABA.
研究领域:
生物工程
·
食品科学
✓ 已验证
DOI
高影响因子
Results in Chemistry
·
2021
·
IF 0
Yetao Jiang,Xiaoyu Wang,Zhen Wu,Jiaxing Xu,Lei Hu,Lu Lin
Food grade xylooligosaccharides (XOS) have a high application value, but most of the reported purification methods of XOS use organic solvents, which has significant problems such as large amount of solvent, residual solvent, and difficulty in solvent recovery. In addition, although there are many reported methods of separation and purification, quantitative analysis is lacking for each specific treatment step, such as sugar loss rate, decolorization rate, protein removal rate, and desalination rate. Therefore, purification of XOS from bamboo with non-organic solvent to prepare food grade functional sugars was presented by this study. What’s more, quantitative analysis and optimization was made for each step of separation, which was of great significance for guiding the actual production. Overall, through activated carbon adsorption, ion exchange and membrane filtration comprehensive treatments, food grade XOS were obtained from bamboo with 7.5% yield, a purity of 92.3%, and a total sugar proportion as high as 98.9%.
研究领域:
食品科学
·
生物化学
✓ 已验证
DOI
FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Ting Du,Shaochi Wang,Xiang Li,Lizhi Liu,Jianlong Wang,Wentao Zhang
The implementation of innovative packaging solutions in fresh food is playing an increasingly important role in driving the global transformation towards sustainability. Here, we demonstrated a novel GRAS preservative coating driven by intermolecular hydrogen bond self-assembly between food-derived tannic acid (TA) and gelatin (Gel). The reported TA/Gel coatings feature desirable antibacterial and antioxidant effects and good adhesion ability. Furthermore, the TA/Gel coatings demonstrate excellent performance in different packaging scenarios, demonstrating desirable preservation performance as sprayable coatings. For fresh-cut apples at 4 °C preservations, the shelf life was extended to 14 days with good commercial quality (including preferable color, protective hardness, sugar content, and weight). For fresh lettuce and beef stored at room temperature, the bactericidal rate reached more than 99% and the sensory quality are maintained well. More importantly, the green and minimalist synthesis process we proposed was expected to achieve scale-up production. Therefore, this work represents a technological solution that inspires the application of food-derived GRAS components to solve food safety problems, guiding an innovative trend for future food development.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2024
·
IF 11
Xiaolong Li,Zihao Wei
Janus droplets exhibit an asymmetric structure, where one droplet has two compartments with different properties. However, food-grade Janus droplets are rarely reported. In this work, food-grade Janus droplets composed of alcohol-soluble protein and alginate were fabricated for the first time by the one-step in-situ method. Segregative phase separation and interfacial equilibrium of zein and alginate solutions were the prerequisites for the formation of food-grade Janus droplets. Segregative phase separation occurred when the concentration of zein and alginate solutions was increased. The zein in the aqueous phase synergistically reduced the oil-water interfacial tension with polyglycerol polyricinoleate (PGPR), but the alginate weakened the interfacial ability of PGPR, resulting in an increase of oil-water interfacial tension. Therefore, the interfacial tension difference between zein/oil and alginate/oil could be regulated by changing the concentration of zein and alginate solutions, which was beneficial to the interfacial equilibrium. The droplet size of food-grade Janus droplets could be adjusted by the concentrations of zein and alginate solutions. In addition, the Janus droplet structure could be further controlled by the volume ratio of zein and alginate solutions. The destabilization of food-grade Janus droplets was dominated by coalescence and sedimentation. The construction of food-grade Janus droplets is expected to provide a structural basis for the construction of food-grade Janus particles and promote the development of food technology.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2018
·
IF 4.946
Nataliya A. Gavrilenko,Dmitrii A. Fedan,Nadezhda V. Saranchina,Mikhail A. Gavrilenko
A novel colorimetric sensor has been proposed for sensitive and accurate detection of iodine forms using polymethacrylate matrix, which also has the outlook for use with samples without pre-treatment and is suitable to fit in a portable instrument for in situ iodine analysis. This determination method is based on interaction of polymethacrylate matrix with iodine forms followed by measurement of absorbance at 370 nm. The principle of this colorimetric sensor is not ordinary colorimetry , but a new colorimetric strategy that combines solid phase extraction and spectrophotometric determination of a target substance following completion of the color change processes. This method ensures determination of 0.05–80.0 µg·g −1 of iodine with the detection limit of 0.02 µg·g −1 . The testing results show that this polymethacrylate matrix can be used for determination of iodine in solutions, food grade salt and iodinated mineral water.
研究领域:
分析化学
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Fundamental Research
·
2022
·
IF 0
Hongguang Liao,Yanji Chu,Shenglong Liao,Yonglin He,Yingchao Ma,Yapei Wang
Photothermal therapy has aroused great attention and showed promising potential in minimally invasive tumor ablation, but the clinical translation is still stifled by the concerns of unwanted injury to normal tissues. The safety concerns might be completely solved only when the two security obstacles of “material-toxicity” and “photo-toxicity” were overcome simultaneously. Herein, a completely non-toxic food-grade photothermal transduction agent (PTA) with double safety guarantees was invented, which shows an absolute transformation of the photothermal effect from “0” to “1” after being triggered by an acidic tumor microenvironment. Inspired by the classical starch-iodine test, a preprogrammed [starch-KI-KIO 3 ] complex was prepared in large quantities through a modified wet-milling procedure. It's demonstrated that a macroscopic consecutive reaction could be triggered by low pH to produce the starch-iodine complex which can generate lethal temperature under the near-infrared light irradiation. Meanwhile, the PTA shows excellent biocompatibility with no “material-toxicity” owing to the raw materials drawn from our daily food. Animal experiments reveal that the tumor microenvironment can activate the switch of photothermal effect from “0” to “1” successfully, which is thus responsible for the discriminative photo-damage to the tumor region while no “photo-toxicity” to normal tissue. The good treatment efficacy confirms the feasibility of such photothermal transduction agents with double safety guarantees in clinical applications.
研究领域:
医学
·
生物材料科学
✓ 已验证
DOI
Journal of Inorganic and Organometallic Polymers and Materials
·
2024
·
IF 3.9
Sando Muna Sarhan,Jawad Ali H.,Farhan Ahlam M.
A quaternary composite adsorbent of chitosan-polyvinyl alcohol/food grade algae/ montmorillonite clay (CS-PVA/FGA/MMT) was synthesized by hydrothermal process to be a promising adsorbent for the removal of cationic methyl violet 2B dye (MV 2B). The adsorption working variables including CS-PVA/FGA/MMT dosage (A: 0.02–0.1 g/100 mL), pH of the dye solution (B: 4–10) and contact duration (C: 20–480 min) were optimized using response surface methodology with Box-Behnken design (RSM-BBD). The optimal conditions of the adsorption key parameters were confirmed by desirability function test and identified to be CS-PVA/FGA/MMT dosage of 0.099 g/100 mL and solution pH of 8. The equilibrium adsorption studies revealed that the adsorption of MV 2B dye on CS-PVA/FGA/MMT surface follows the Langmuir isotherm model and the pseudo-second-order kinetic model. The highest adsorption capacity of CS-PVA/FGA/MMT towards MV 2B was determined to be 105.7 mg/g at 25 ⁰C based on the Langmuir isotherm model parameters. The suggested mechanism of MV 2B adsorption by CS-PVA/FGA/MMT can be assigned to the various possible interactions such as electrostatic forces, n-π stacking, and H-bonding. This study shows that the synthesized CS-PVA/FGA/MMT material possesses a unique structure and preferable adsorption capabilities towards cationic dye. Therefore, it offers a practical solution for removing harmful cationic dyes from contaminated wastewater.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Huan Gong,Ye Zi,Guangyi Kan,Li Li,Cuiping Shi,Xichang Wang,Jian Zhong
Herein, a safe desolvation and crosslinking method was developed to prepare food-grade bovine bone gelatin (BBG) nanoparticles for Pickering emulsion stabilization. The nanoparticle-like structures were formed by adjusting pH 9.0 and adding ethanol, and then stable nanoparticles were formed by using N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) and N -hydroxysuccinimide (NHS) as crosslinker. Compared with other pH (2.5, 5.0, 7.0, and 12.0), pH 9.0 was the appropriate pH to prepare BBG nanoparticles. Individual nanoparticles (6.50 nm in height), oligomeric nanoparticles (13.42–22.52 nm in height), and polymeric nanoparticles (obvious liquid-precipitate separation) were formed at EDC·HCl/NHS concentrations of 6, 9–12, and 15–20 mg/mL, respectively. The oligomeric nanoparticles induced the highest emulsion creaming stability. The emulsion creaming ability increased with the increase of BBG nanoparticle concentrations. Low NaCl concentration (e.g., 100 mmol/L) could increase the emulsion creaming stability. Finally, 4 °C was the best storage temperature for fish oil-loaded Pickering emulsions.
研究领域:
食品科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2024
·Vol. 105
·期 2
·1080-1090
·
IF 3.3
Yingshan Xie,Hongyan Li,Zeyuan Deng,Han Peng,Yanfang Yu,Bing Zhang
BACKGROUND Food-grade Pickering particles, particularly plant proteins, have attracted significant interest due to their bio-based nature, environmental friendliness, and edibility. Mulberry-leaf protein (MLP) is a high-quality protein with rich nutritional value and important functional properties. It has special amphoteric and emulsifying characteristics, making it valuable for use in Pickering emulsions. This study aimed to investigate the feasibility of using MLP nanoparticles as solid particles to stabilize Pickering emulsions. RESULTS The particle size of MLP nanoparticles was less than 300 nm under neutral and alkaline conditions. At pH 9, the zeta potential value reached −34.3 mV, indicating the electrostatic stability of the particles. As ion concentration increased, the particle size of MLP nanoparticles increased, and the zeta potential decreased. Throughout the storage process, no obvious aggregation or precipitation was observed in the dispersion of MLP nanoparticles, indicating strong stability. The particle size of the Pickering emulsion decreased with the increase in protein concentration. When the protein concentration was low, the particles on the oil–water interface became sparse, resulting in poor stability of the prepared emulsion and making it susceptible to aggregation and thus larger particle sizes. Increasing the oil-phase ratio to 70% (v/v) promotes the formation of Pickering emulsions, which exhibit exceptional stability when MLP nanoparticles are fixed at a concentration of 20 mg mL −1 . CONCLUSION The overall findings indicated that MLP nanoparticles have potential as food-grade materials for Pickering emulsions, marking a novel application of these nanoparticles in the food industry. © 2024 Society of Chemical Industry.
研究领域:
食品科学
·
生物化学
·
胶体化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
AICHE JOURNAL
·
2024
·
IF 3.5
Nan Wang,Yi Li,Xiujie Cheng,Ruiqi Zhang,Qing Zhou,Jiayu Xin,Dongxia Yan,Junli Xu,Xingmei Lu
This study employed titanium catalysts to degrade low-quality PET (polyethylene terephthalate) bottle flakes and subsequently re-polymerized the degradation solution to investigate whether the titanium catalyst could restore the physical and chemical properties of the degraded PET bottle flakes. The reaction process of property restoration was characterized using GPC, DSC, ICP, NMR, and so forth. The mechanism of titanium catalyst-catalyzed PET polymerization was explored through simulation calculations. The results indicate that the waste PET bottle flakes have been restored to the standard of first-grade PET bottle flakes under the degradation and re-polymerization processes with the aid of dibutyl ethylene glycol titanate catalysts. The Ti ion in the recycled PET is stable and the metal ion leached from the restored PET in the strong acid environment meets food-grade safety requirements. This study is expected to provide a new way for recycling waste PET bottle flakes.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Jun Li,Jie Zhang,Xianling Yang,Ao Kong,Nan Wang,Jie Tang,Xiaoqi Yu
Accurate on-site analysis of food quality is of great significance for ensuring public health. Among them, ascorbic acid (AA) is an essential micronutrient widely used as an additive in juices and drugs to improve food quality and human health. In this work, we developed food-grade Fe-β-Cyclodextrin(Fe-β-CD) nanozymes based on inexpensive and readily available β-cyclodextrin and iron ions for the detection of AA. Fe-β-CD confirmed excellent peroxidase-like activity and oxidized colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to oxide TMB. AA could inhibit the oxidation reaction and cause blue to fade. Based on the above principles, Fe-β-CD nanozymes exhibited a low detection limit (3.4 μM) for detecting AA, with a wide linear range (10–300 μM). This method had been successfully used for the detection of AA in fruits and vitamin C tablets, and the results were consistent with the specified values. More importantly, an integrated smartphone-assisted Fe-β-CD@test strip colorimetric application platform constructed by one-pot method, the test strip also had better stability, and could be combined with smartphones to achieve convenient AA detection without using any instruments, which showed enormous potential for rapid and low-cost colorimetric detection of AA.
研究领域:
食品科学
·
生物化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2020
·
IF 3.557
Manyu Lan,Yuan Song,Shiyi Ou,Jie Zheng,Caihuan Huang,Yong Wang,Hua Zhou,Wenzhong Hu,Fu Liu
Water-in-oil (W/O) Pickering emulsions were successfully synthesized by water-dispersible phytosterol (PS) particles formed through simple antisolvent precipitation. The effects of the organic/aqueous ratio on the particle morphology, crystallinity, and contact angle were investigated. Sheet-like PS particles with reduced crystallinity were further used as W/O Pickering emulsion stabilizers. The properties of the formed W/O emulsions could be transformed by changing the oil type, water-phase fraction, or particle contents. Results showed that emulsions with 80% water fraction could be stabilized by 3% particles in the aqueous phase, where dodecane was used as the oil phase. W/O Pickering emulsions stabilized by PS particles showed temperature responsiveness. When dried, PS particles could be well dispersed either in the water or oil phase to stabilize W/O Pickering emulsions. Therefore, this kind of PS particles could not only enrich the family of food-grade Pickering stabilizers, especially the W/O type, but also provide a smart Pickering stabilizer to fabricate environmental-responsive emulsion products.
研究领域:
食品科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）