Nutrients
·
2022
·Vol. 14
·期 15
·3095
·
IF 6.706
Zhi Huang,Ping Guo,Ying Wang,Ziming Li,Xiaochen Yin,Ming Chen,Yong Liu,Yuming Hu,Bo Chen
Objective: The present study aims to measure docosahexaenoic acid (DHA) in both the plasma and erythrocyte of a child population and compares them with respect to their associations with dietary and metabolic risk patterns. Methods: A cross-sectional study was conducted, and a total of 435 children ages 5–7 years old were recruited. Diet information was collected using a food frequency questionnaire (FFQ). The physical indicators, blood pressure, and glycolipid metabolic indicators were determined. The plasma and erythrocyte DHA were analyzed using a gas chromatography mass spectrometer. Principal component analysis was used to identify dietary and metabolic risk patterns. Multivariate regression analyses were used to investigate the associations of DHA status with dietary and metabolic risk patterns. Results: A significant correlation between plasma and the erythrocyte DHA concentration was found (r = 0.232,p< 0.001). A diversified dietary pattern characterized that a high intake of diversified foods had a positive association with the plasma DHA level (β = 0.145, 95% CI: 0.045~0.244,p= 0.004). Children of obesity risk patterns with a high weight, pelvis breadth, BMI, upper arm circumference, and chest circumference had lower plasma DHA concentrations (OR = 0.873, 95% CI: 0.786~0.969,p= 0.011). Children with higher plasma and erythrocyte DHA concentrations were adhered to blood lipid risk patterns with high CHOL and LDL-C levels. The plasma DHA (OR = 1.271, 95% CI: 1.142~1.415,p< 0.001) had a stronger association with a blood lipid risk pattern than erythrocyte (OR = 1.043, 95% CI: 1.002~1.086,p= 0.040). Conclusions: The diversified dietary pattern had a higher plasma DHA concentration. Lower levels of plasma DHA were positively associated with obesity in children. DHA in plasma appears to be more strongly associated with blood lipid metabolism than erythrocyte. Plasma DHA may be a more sensitive bidirectional biomarker to evaluate the recently comprehensive diet intake and metabolic risk of children.Keywords:docosahexaenoic acid;plasma;erythrocyte;dietary patterns;metabolic risk patterns
研究领域:
营养学
·
儿科医学
·
代谢研究
✓ 已验证
DOI
PubMed
高影响因子
Revue Francaise d Allergologie
·
2021
·
IF 0.288
H. Rezapour,M. Fereidouni,Z. Asadi,M. Saharkhiz,M. Ayadilord,S. Mahmoudzadeh,M.R. Shadmand Foumani Moghadam,G.A. Ferns,A. Bahrami
The prevalence of allergic disorders has been increasing globally, and it may be useful to identify the modifiable factors associated with it. Diet has been identified as one possible lifestyle factor implicated in the pathogenesis of allergic diseases. The goal of this study was to evaluate the associations between dietary patterns and the presence of allergies in a group of young women in eastern Iran. In all, 181 female students were enrolled. Screening for presence of allergic diseases, including allergic rhinitis (AR), asthma and eczema, was performed by an expert allergist. Information about dietary intake was collected using a validated 65-item food frequency questionnaire. Exploratory factor analysis was used to evaluate the relationships between food/nutrition variables. Serum immunoglobulin (Ig)E levels were significantly higher in the group in the third tertile (highest adherence) for a Western dietary pattern compared to the group in the first tertile (lowest adherence). The multivariate odds ratio for presence of allergic rhinitis (AR) was 2.5 (95% CI:1.1-5.1) for the highest compared to lowest tertile of the Western dietary pattern score. However, no significant relationship was found between a traditional dietary pattern and AR, asthma or eczema. Our findings indicate a potential role in the development of AR of the Western dietary pattern, which is characterized by high intake of dairy products, snacks, nuts and sugar. Since diet is a modifiable factor, the relationship between AR and a Western dietary pattern may have clinical implications, particularly in subjects with other risk factors for developing AR. Résumé La prévalence des troubles allergiques a augmenté à l’échelle mondiale, et il peut être utile d’identifier les facteurs modifiables qui y sont associés. L’alimentation a été identifiée comme un facteur de style de vie possible impliqué dans la pathogenèse des maladies allergiques. Le but de cette étude était d’évaluer les associations entre les habitudes alimentaires et la présence d’allergies dans un groupe de jeunes femmes de l’est de l’Iran. Au total, 181 étudiantes se sont inscrites. La présence de maladies allergiques dont la rhinite allergique (RA), l’asthme et l’eczéma a été identifiée par un allergologue expert. Les informations sur l’apport alimentaire ont été recueillies à l’aide d’un questionnaire de fréquence alimentaire validé de 65 éléments. Une analyse factorielle exploratoire a été utilisée pour évaluer les relations entre les variables alimentaires/nutritionnelles. Les taux sériques d’immunoglobulines (Ig) E étaient significativement plus élevés dans le groupe du troisième tertile (adhérence la plus élevée) pour un régime alimentaire occidental par rapport au groupe du premier tertile (adhérence la plus faible). L’odds ratio multivarié d’avoir une rhinite allergique (RA) était de 2,5 fois (IC à 95 % : 1,1 à 5,1) pour le tertile le plus élevé par rapport au tertile le plus bas du score de modèle alimentaire occidental. Mais, aucune relation significative n’a été trouvée entre un régime alimentaire traditionnel et la RA, l’asthme ou l’eczéma. Nos résultats indiquent un rôle potentiel du modèle alimentaire occidental, caractérisé par sa teneur élevée en produits laitiers, en collation, en noix et en sucre, dans le développement de la RA. Étant donné que le régime alimentaire est un facteur modifiable, la relation entre la RA et un modèle alimentaire occidental peut avoir des implications cliniques, en particulier chez ceux qui ont d’autres facteurs de risque de développer une RA.
研究领域:
营养学
·
过敏性疾病研究
·
公共卫生
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）