JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
·
2018
·
IF 0.827
Huihui Wu,Hanying Jin,Guangxin Yuan,Jacques Crommen,Jing Zhang,Qiqin Wang
Urea and allantoin are two important additives in cosmetic products for the treatment of dry skin as well as for skin protection and regeneration. In this research, a highly hydrophilic monolith prepared by co-polymerization of N,N-dimethyl-N-acryloyloxyethyl-N-(3-sulfopropyl)ammonium betaine (SPDA) and N,N’-methylenebisacrylamide (MBA) was first exploited for the simultaneous quantification of urea and allantoin in cosmetic products by nano-HPLC in the HILIC mode. The whole separation process could be completed within six minutes using isocratic elution. Due to the extremely high hydrophilicity of this monolithic column, a relatively low content (80%) of ACN in the mobile phase was required to achieve satisfactory separation, and therefore the solubility problems for polar compounds was also avoided in comparison with previously reported results on the commercial columns. Method validation was also accomplished with respect to linearity, reproducibility, selectivity, recovery, stability, LOD and LOQ. The recoveries of urea and allantoin from spiked cosmetic samples were 95.6%-100% and 94.1%-99.9%, respectively. Validation results indicate that this HILIC method based on the miniaturized poly(SPDA-co-MBA) monolith can be applied successfully to the fast and efficient determination of urea and allantoin in cosmetic samples. The miniaturized column format, the low sample consumption (20 nL), and excellent separation efficiency could make this highly hydrophilic monolith an attractive choice for the detection of trace polar analytes from complex samples in future.
研究领域:
分析化学
·
化妆品科学
✓ 已验证
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
·
2025
·
IF 2.8
Zhuo Mi,Wenkang Zhang,Han Wang,Xingyi Qi,Shuo Wang,Jiayi Song,Ping Su,Yi Yang
Glycopeptides are an important biomarker, which play a crucial role in various biological processes. Due to their low abundance and the presence of interfering macromolecular proteins, enrichment of glycopeptides is necessary before testing. However, most materials for enriching glycopeptides have high site resistance, relatively low surface area, and limited recognition sites. Herein, a highly hydrophilic two-dimensional (2-D) covalent organic framework (NUS-10) loaded with chitosan (CS) (denoted as NUS-10@CS) had been synthesized. After enrichment with NUS-10@CS, a total of 34 glycopeptides from horseradish peroxidase (HRP) tryptic digests were detected, demonstrating a high enrichment efficiency for glycopeptides from model glycoprotein digestion. Meanwhile, the material exhibited ultra-high adsorption capacity (1 fmol/μL HRP), excellent selectivity (HRP tryptic digest/bovine serum albumin (BSA) tryptic digest = 1:2000), macromolecular protein anti-interference ability (HRP tryptic digest/BSA = 1:2000) and good binding capacity (200 mg/g). Additionally, 712 glycopeptides corresponding to 200 glycoproteins were identified from 3 µL human serum. NUS-10@CS was promising for glycopeptide analysis, helping to identify potential disease biomarkers more efficiently, and leading to easier and more accurate diagnosis of diseases, which was essential for early intervention and treatment.
研究领域:
生物化学
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蛋白质组学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Soft Matter
·
2021
·Vol. 17
·期 12
·3346-3357
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IF 3.679
Kangle Jia,Yongshun Guo,Yue Yu,Junjie Zhang,Longfei Yu,Wu Wen,Yuliang Mai
Using solely highly hydrophilic particles to stabilize emulsions, especially high internal phase emulsions, has always been an important challenge. Here pH-responsive Pickering emulsions stabilized by a low concentration of bare highly hydrophilic Ludox CL nanoparticles without surface modification or addition of surfactants are developed at neutral pH. The dispersed nanoparticles can be transformed into an aggregate state with a network-like structure near the isoelectric point, which contributes to the stabilization of the emulsions. Moreover, the vdW attraction between particles and droplets also plays a key role in the formation of emulsions, which can make the aggregated nanoparticles adsorb tightly around the droplets rather than penetrate the oil–water interface. The formed protective armor and network-like aggregates separate droplets from each other to prevent coalescence. At a low nanoparticle concentration (0.5 wt%), a high internal phase emulsion can be formed and can last up to half a year. This system can emulsify not only the hydrocarbon oil but also the fluoroalkane oil phase. Finally, organic–inorganic composite particles are fabricated using the template action of the Pickering emulsions. The method of preparing composite particles is more convenient than the traditional Pickering emulsion polymerization which often requires the modification of the surface of the hydrophilic particles or the addition of auxiliary monomers. This study provides a simple green strategy for the preparation of a more stable Pickering emulsion stabilized by surface-inactive nanoparticles and will broaden the scope of applications.
研究领域:
材料科学
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化学工程
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Xiaoyan Yu,Hua Lai,Hongjun Kang,Yuyan Liu,Youshan Wang,Zhongjun Cheng
Directional self-transportation of tiny droplets is significant in many fields. However, almost all existing studies focus on the phenomenon in air, and to realize similar performance in complex environments, such as oil, is still extremely rare. Here, we report a TiO2-coated conical spine (TCS) and demonstrate underoil directional self-transportation of water droplets on its surface. It is found that high surface hydrophilicity resulting from UV irradiation is necessary to achieve the self-transportation of water in oil. The critical water contact angle in oil is about 57°, and the maximal transport velocity can reach 1.4 mm/s. Mechanism analysis reveals that the excellent self-transportation property is ascribed to the combined effect between the Laplace force (FL) caused by the conical gradient structure and the hysteresis reduction resulting from the high hydrophilicity. Moreover, based on the special underoil self-transportation performance, a droplet-based microreaction and demulsification of water-in-oil emulsions were demonstrated using the TCS. This work reports the self-transportation of water in oil, which could provide some fresh ideas for designing new superwetting self-transportation materials.
研究领域:
材料科学
·
界面化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Chao Liu,Yawei Liu,Yongqiang Guo,Chao Wang,Zhen Hu,Chunhua Zhang
In this study, a novel PA-g/co-PVP reverse osmosis (RO) composite membrane with high-hydrophilic, antifouling, high salt rejection properties, was prepared according to the principle of sand-fixing grass effect for pharmaceutical wastewater treatment. N-vinyl-2-pyrrolidone (NVP) was used as a “seed agent” that was seeped into a low cross-linked polyamide (PA) film. A hydrophilic molecular brush of polyvinylpyrrolidone (PVP) grafted on the PA surface (PA-g-PVP) similar to grass growing on sand and a cross-linked copolymer layer of PA and NVP (PA-co-NVP) similar to grass roots distributed in sand, as well as an interlayer cross-linking between PA separation layer and PES ultrafiltration membrane with a highly stable interfacial structure, synchronously occurred through γ-ray radiation. Upon incorporation of 1.0% of NVP, the resultant PA-g/co-PVP membrane achieved 18.8° water contact angle and high flux recovery ratio (FRR) values of 91.23%, 96.28%, and 93.67% for the foulants of bovine serum albumin (BSA), sodium alginate (SA), and sodium dodecyl sulfate (SDS), respectively. The FRR value of pharmaceutical wastewater-polluted membrane after cleaning was 94.30%. The PA-g/co-PVP RO membrane showed outstanding separation stability due to the radiation cross-linking reactions, which limit matrix swelling and interface delamination similar to the action principle of sand-fixing grass. These merits prove that the RO membrane developed in this study can be used in many applications, including small organic molecular wastewater separation.
研究领域:
环境科学
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材料科学
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药学
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产品关联
DOI
高影响因子
ANALYST
·
2018
·Vol. 144
·期 5
·1555-1564
·
IF 3.864
Yiqiong Chen,Dandan Zhu,Xinyue Ding,Guomin Qi,Xucong Lin,Zenghong Xie
A novel polyhedral oligomeric silsesquioxane (POSS)-containing aptamer-modified hybrid affinity monolith with excellent hydrophilicity and unique architecture without Si–OH groups is presented herein, and the nonspecific adsorption caused by the hydrophobic nature of the monolithic column or polar interaction with silanol groups is minimized. Via a simple “one-pot” procedure, hydrophilic monomers were facilely polymerized with the POSS-methacryl substituted (POSS-MA) and aptamer; a highly hydrophilic nature was obtained and the lowest contact angle of 11° was achieved. By using ochratoxin A (OTA) as the model analyte, highly selective recognition of OTA in the mixture was achieved and the control of nonspecific interactions and the cross-reactivity of OTB and AFB1 were significantly improved. The recovery yield of OTB caused by nonspecific adsorption in the resultant monolith was only about 0.1% and remained steady even with the coexistence of a high OTB content (OTA : OTB = 1 : 50), which reached the best level to date and was obviously less than the 6.1% occurring in the hydrophobic POSS-containing control monolith, 8.3% in the POSS-PEI@AuNPs@aptamer affinity monolith and 18.7% in the silica-hybrid affinity monolith. When applied to wine and wheat samples, the nonspecific adsorption was significantly reduced and efficient discrimination of OTA was obtained with better results than that of the hydrophobic POSS-containing affinity column. This provides an attractive tool for minimizing the nonspecific adsorption for highly selective on-column recognition.
研究领域:
分析化学
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材料科学
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Longxiang Qian,Hao Xu,Yiwei Lu,Zezhong Chen
In response to the adverse events caused by the detachment of coatings during coronary guidewire interventions, this research investigates and optimizes the preparation process of a polyvinyl alcohol (PVA)/polyvinylpyrrolidone (PVP) coating with high adhesion and hydrophilicity. Using thermoplastic polyurethane (TPU) as the substrate, the coating was prepared via polydopamine (PDA) deposition and UV curing technology. The amounts of PVA, PVP, and polyethylene glycol diacrylate (PEGDA), as well as the proportion of the photoinitiator, were optimized through orthogonal experiments, significantly enhancing the hydrophilicity and adhesion of the coating. The optimized hydrophilic coating achieves a minimum water contact angle of 7.4°. The coating with the optimized formulation has a water contact angle of 12.2°, reaches grade 0 adhesion in the cross-cut test, and maintains a stable friction coefficient of 0.16. After water exposure, the water contact angle was 22.6°, and the friction coefficient remained below 0.2. Cytotoxicity tests showed cell viability between 90 % and 110 %, and the hemolysis rate was less than 5 %. These results indicate that the coating exhibits excellent hydrophilicity, adhesion, water resistance, and stability, offering significant potential to improve the safety and operability of coronary interventional guidewires, reduce coating-related adverse events, and enhance surgical quality and safety.
研究领域:
生物医学工程
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材料科学
·
表面工程
·
医疗设备
✓ 已验证
产品关联
DOI
高影响因子
Polymer Chemistry
·
2021
·Vol. 12
·期 40
·5803-5814
·
IF 5.582
Xiao-han Pan,Jian-hua Zu
Novel cation exchange nonwoven PP-g-SSS/GMA containing epoxy and sulfonic groups was successfully prepared via radiation-induced simultaneous grafting polymerization by attaching glycidyl methacrylate (GMA) and styrene sulfonic sodium (SSS) monomers onto nonwoven polypropylene (PP). The ion exchange capacity of the obtained PP-g-SSS/GMA reached more than 1.5 mmol g−1 and the content of the epoxy groups with potential modifiable properties was above 3 mmol g−1. The relative content of the two functional groups could be adjusted via changing the initial monomer concentration ratio. Scanning electron microscope (SEM) images showed that the polymer surface was fully covered with grafts after modification and those amorphous grafts diluted the crystallinity of the matrix, as revealed via differential scanning calorimetry (DSC). Attenuated total reflection spectroscopy (ATR) confirmed the successful grafting of GMA and SSS onto PP nonwovens. Water contact angle measurements showed that the contact angle decreased from 100.94° for the PP matrix to 0° for PP-g-SSS/GMA with a 56% degree of grafting, indicating the outstanding hydrophilicity of PP-g-SSS/GMA upon the introduction of SSS. Besides this, the epoxy groups on PP-g-SSS/GMA could be further modified via reacting them with chemical compounds with selective adsorption groups. Ag(I) adsorption tests proved that PP-g-SSS/GMA@EDA obtained via the ethanediamine (EDA) modification of epoxy groups on PP-g-SSS/GMA shows excellent selectivity towards Ag(I), and the hydrophilicity brought about by sulfonic groups also ensured a fast adsorption rate. The novel cation exchange nonwoven PP-g-SSS/GMA fabric has potential applications in water treatment, as its strong hydrophilicity could speed up the diffusion rates of adsorbed ions, and further functionalization of the epoxy groups could enable it to selectively adsorb ions in aqueous solutions.
研究领域:
材料科学
·
环境工程
·
高分子化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）