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Applied Sciences-Basel · 2018 ·Vol. 8 ·期 9 ·1481 · IF 1.689

Processing and Prebiotics Characteristics of β-Glucan Extract from Highland Barley

Yao Ren,Haoyu Xie,Li Liu,Dongying Jia,Kai Yao,Yuanlong Chi

β-glucan extract (GE) was obtained from highland barley bran using alkaline–acid–alcohol extraction method. The stability, solubility, foaming ability, and prebiotics characteristics of GE were assessed consecutively. GE demonstrated excellent heat stability (hardly degraded at 220 °C) and pH stability, especially at neutral or alkaline condition, and its solubility was significantly influenced by temperature instead of pH or NaCl, achieving 0.91 g/100 g at 100 °C. Good foaming ability and foam stability of GE were observed during low temperatures (≤40 °C), neutral or alkaline condition. GE indicated a strong anti-digestibility capacity of resisting the hydrolysis of α-amylase and simulated human gastric acid. Interestingly, GE could effectively promote the growth ofLactobacillus bulgaricusandBifidobacterium adolescentis, which was close to fructooligosaccharide. The results of this study could offer valuable information for the application of β-glucan from highland barley as prebiotics in promoting human intestinal health metabolism.Keywords:β-glucan;highland barley;processing characteristics;prebiotics

CAS / MDL: 9000-90-2 573-58-0
研究领域: 食品科学 · 营养学
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Heliyon · 2024 · IF 3.4

Synergistic Adsorption and Photocatalysis Study of TiO2 and Activated Carbon Composite

Yihang Yue,Xiaoju Yue,Xiaofeng Tang,Lin Han,Jinnong Wang,Shifeng Wang,Chun Du

The discharge of organic pollutants by the textile and dyeing industries presents an escalating threat to aquatic environments, necessitating the development of effective remediation strategies. This study introduces the utilization of graphite-like structured activated carbon (AC), derived from highland barley straw—a biomass unique to the Plateau regions of China, including Tibet, Qinghai, and Gansu—as a support material for the TiO 2 catalyst. TiO 2 /AC composites with different TiO 2 loadings were synthesized by ultrasonic impregnation. The TiO 2 /AC composites were found to be polycrystalline materials composed of anatase and rutile phases. The TiO 2 nanoparticles are well-dispersed over the surface of the AC. The photocatalytic activity of these composites was evaluated through their capacity to degrade a methylene blue (MB) solution upon irradiation. It was observed that the inclusion of TiO 2 increases the number of adsorption sites and active sites for methylene blue, with the photocatalytic activity being notably higher at a 3-wt% TiO 2 loading, achieving a remarkable 99.6 % degradation efficiency for 100 mg/L MB within 100 min. The experimental kinetic data for the photocatalytic process follow the pseudo-first-order kinetic model. Furthermore, TiO 2 /AC retains high photocatalytic activity after five reaction cycles. This research provides valuable insights into the application of biomass-derived materials for the purification of water, offering a sustainable solution to both pollution and agricultural waste challenges in Plateau areas of China.

研究领域: 环境科学 · 材料科学
✓ 已验证 DOI PubMed 高影响因子
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2021 · IF 6.953

Comparison of distribution and physicochemical properties of β-glucan extracted from different fractions of highland barley grains

Yao Li,Maolan You,Haibo Liu,Xiong Liu

Highland barley grains were roller-milled to produce five different fractions (B-1, B-2, B-3, B-4, and B-5). The distribution and physicochemical properties of β-glucans from five roller-milled fractions were investigated. The B-4 fraction contained the highest concentration of β-glucan (4.40%), and the outermost bran (B-1) had the lowest β-glucan content (1.01%). Besides, β-glucans from inner core B-5 (BG-5) had higher M w (6.482 × 10 5  g/mol), whereas β-glucans from outer bran B-1 (BG-1) showed lower M w (5.859 × 10 4  g/mol) than those from other fractions. Accordingly, the viscosity of BG-5 was highest (0.038-0.365 Pa·s), and the water solubility index of BG-1 was highest (50.43–90.71%). BG-5 showed stronger foam stability and emulsifying properties but weaker foaming capability, while BG-1 exhibited stronger foaming capability. The foaming capability and emulsifying properties of β-glucan samples were better under the neutral condition (pH = 7). The foam capabilities of all β-glucan samples displayed higher values at 65 °C, and emulsifying properties exhibited higher values at 45 °C. This study is expected to promote the application of highland barley β-glucans in food industry.

CAS / MDL: 9000-90-2
研究领域: 食品科学 · 植物化学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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International Journal of Low-Carbon Technologies · 2023 · IF 2.3

Activated carbon derived from highland barley straw for removing heavy metals and organic pollutants

Yue Yihang,Yu Zexu,Yue Xiaoju,Zhou Wenkai,Wang Saiyu,Yang Yanxi,Lao Youliang,Yang Mengdi,Du Chun,Wang Shifeng

Biomass activated carbon has been widely used in the field of wastewater treatment because of its unique properties, such as high specific surface area and porosity, good adsorption capacity, good mechanical strength, rich functional groups and thermal stability. In this work, highland barley straw is recycled and made into activated carbon using hydrothermal carbonization and alkaline activation processes in which the dependence of the product properties on the activation temperature, as one of the critical parameters, is intensively investigated. Under the optimum conditions at an activation temperature of 1100 °C, activated carbon in the form of mesoporous structure and polycrystalline graphite was produced with a specific surface area as large as 1906 m2/g, which is superior to that of commercial products. To investigate the absorption capacity of the prepared samples for pollutants in water, such as heavy metals and organics, potassium dichromate and methylene blue were utilized as the simulated pollutants. The removal efficiency of Cr6+ and methylene blue in water reached 90.3 % within eight hours and 87.7 % within four hours, respectively, and this demonstrated an excellent absorption capacity for activated carbon converted from agricultural waste. Th e successful fabrication of activated carbon with a super large specific surface area and remarkable adsorption ability derived from highland barley straw through a hydrothermal carbonization and alkaline treatment demonstrated the feasibility of the “turning waste into wealth” recycling strategy. It has also shown great potential for use in environmental protection applications, especially for water purification.

研究领域: 环境科学 · 材料科学
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JOURNAL OF FOOD SCIENCE · 2024 · IF 3.2

Ultrafine grinding improves the nutritional, physicochemical, and antioxidant activities of two varieties of whole-grain highland barley

Lu Liu,Jingwen Xu,Ge Zhang,Nisi Gao,Xuebing Xu,Renyong Zhao

Effects of ultrafine grinding on the nutritional profile, physicochemical properties, and antioxidant activities of whole-grain highland barley (HB) including white highland barley (WHB) and black highland barley (BHB) were studied. Whole-grain HB was regularly ground and sieved through 80 mesh get 80 M powder, and HB was ultrafine grounded and sieved through 80 mesh, 150 mesh, and 200 mesh get 80UMM, 150UMM, and 200UMM samples. Particle size of WHB and BHB reduced significantly after ultrafine grinding. As the particle size decreased, moisture content of WHB and BHB decreased significantly, whereas fat content increased significantly. Redistribution of fiber components in WHB and BHB from insoluble to soluble fractions was also observed. Wherein, content of soluble pentosan of WHB and BHB increased significantly from 0.56% and 0.78% (80 M) to 0.91% and 1.14% (200UMM), respectively. Damaged starch of WHB and BHB increased significantly from 8.16% and 8.21% (80 M) to 10.29% and 10.07% (200UMM), respectively. Content of phenolic acid and flavonoid of WHB and BHB and associated antioxidant capacity were increased after ultrafine grinding. Color of L * value increased significantly, a * and b * values decreased significantly, indicating the whiteness of WHB and BHB was increased after ultrafine grinding. Pasting temperature of WHB and BHB decreased, whereas peak viscosity increased. X-ray diffraction patterns of HB showed typical A- and V-style polymorphs and the relative crystallinity of HB decreased as the particle size decreased. Taken together, ultrafine grinding has shown great potential in improving the nutritional, physiochemical, and antioxidant properties of whole-grain HB. Our research findings could help better understand the ultrafine grinded whole grain HB in food industry.

CAS / MDL: 64-19-7 53188-07-1
研究领域: 食品科学 · 植物学 · 营养学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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JOURNAL OF CEREAL SCIENCE · 2025 · IF 3.7

Modification of highland barley starch properties via germination-induced amylase activation and amylopectin reduction

Yongliang Bai,Junwei Yin,Zuanhao Liang,Yu Xia,Shuyan He,Ming Yu,Haiqiang Chen

To investigate the impact of germination on the development of deep-processed products from highland barley starch, this study systematically examined changes in the structure, composition, physicochemical properties, and related enzyme activities of starch during germination. After 72 h of germination, the contents of total starch and amylopectin in highland barley starch decreased significantly ( p  < 0.05). The activities of α-amylase and β-amylase increased dramatically by 19.6-fold and 6.3-fold, respectively. Concurrently, the gelatinization enthalpy ( ΔH ) of the starch decreased significantly, whereas the syneresis rate showed a significant increase ( p  < 0.05). Correlation analysis revealed that the germination treatment enhanced the activities of α-amylase and β-amylase in highland barley, which promoted the enzymatic degradation of amylopectin. This led to a significantly increased starch solubility, syneresis rate, and initial gelatinization temperature( T 0 ), while decreasing starch transparency, termination gelatinization temperature ( T c ), peak temperature ( T p ), and Δ H . The results demonstrate that germinated highland barley starch is suitable for noodle products.

✓ 已验证 DOI 高影响因子
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Nutrients · 2024 ·Vol. 16 ·期 20 ·3518 · IF 4.8

Highland Barley Alleviates High-Fat Diet-Induced Obesity and Liver Injury Through the IRS2/PI3K/AKT Signaling Pathway in Rats

Xiaodong Shi,Wei Song,Boyue Jiang,Jie Ma,Wanyang Li,Mingyao Sun,Hongyuan Cui,Wei Chen

Objectives:Highland barley (HB) consumption offers numerous health benefits; however, its impact on glycolipid metabolism abnormalities induced by a high-fat diet remains unclear. Consequently, this study aimed to investigate the therapeutic effects and underlying molecular mechanisms of HB in the context of obesity;Methods:Rats were fed either a high-fat diet (HFD) to induce obesity or a standard diet (SD) for six weeks. The rats in the HFD group were randomly assigned into five groups: HFD+HFD, HFD+SD, and low (30%), medium (45%), and high (60%) doses of the HB diet for an additional ten weeks. Analyses of serum lipid profiles, liver histology, transcriptomes, and untargeted metabolomes were conducted;Results:HB intake resulted in decreased weight gain, reduced feed intake, lower serum triglyceride and cholesterol levels, and diminished hepatic lipid accumulation. It also improved insulin and fasting blood glucose levels, and antioxidant capacity in the HFD-fed rats. Transcriptome analysis revealed that HB supplementation significantly suppressed the HFD-induced increase in the expression of Angptl8, Apof, CYP7A1, GDF15, Marveld1, and Nr0b2. Furthermore, HB supplementation reversed the HFD-induced decrease in Pex11a expression. Untargeted metabolome analysis indicated that HB primarily influenced the pentose phosphate pathway, the Warburg effect, and tryptophan metabolism. Additionally, integrated transcriptome and metabolome analyses demonstrated that the treatments affected the expression of genes associated with glycolipid metabolism, specifically ABCG8, CYP2C12, CYP2C24, CYP7A1, and IRS2. Western blotting confirmed that HB supplementation impacted the IRS2/PI3K/AKT signaling pathway;Conclusions:HB alleviates HFD-induced obesity and liver injury in an obese rat model possibly through the IRS2/PI3K/Akt signaling pathway.

CAS / MDL: 329-98-6
研究领域: 营养学 · 分子生物学 · 代谢组学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2023 · IF 8.2

The role of guar gum in improving the gel and structural characteristics of germinated highland barley starch

Wentao Pan,Wenmeng Liu,Jinwang Li,Yi Chen,Qiang Yu,Jianhua Xie

Germinated highland barley has been shown to have many health benefits, but the weakening of the starch gel properties during the germination limits its further application. In this study, germinated highland barley starch (GBS) was obtained after germination treatment. Guar gum (GG) was added to explore the effects of gelatinization on the rheology, gel and structural characteristics of GBS, and the potential of preparing gel-based products was also evaluated. The results showed that the addition of GG significantly increased the viscosity, gel strength and viscoelasticity of GBS, which was beneficial to the formation of gel, and promoted its formation of an ordered and compact gel network structure. The study provides a theoretical reference for the preparation of gel-based food with highland barley starch, and increases the application range of highland barley.

CAS / MDL: 7681-52-9
研究领域: 食品科学 · 淀粉化学 · 生物聚合物
✓ 已验证 产品关联 DOI PubMed 高影响因子
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FOOD RESEARCH INTERNATIONAL · 2024 · IF 7

Comprehensive assessment of the anti-obesity effects of highland barley total, insoluble, and soluble dietary fiber through multi-omics analysis

Bing Zheng,Tianxiang Ao,Xiaole Zhao,Yi Chen,Jianhua Xie,Xingcai Gao,Li Liu,Xiaobo Hu,Qiang Yu

The impact of different forms of dietary fiber (total, insoluble or soluble) derived from the same source on health remains incompletely understood. In this study, the effects of total, insoluble, and soluble dietary fiber extracted from highland barley (HDF, HIDF, and HSDF) on combating obesity were evaluated and compared. A high-fat diet (HFD) was used to induce obesity in a murine model, followed by gavage administration of HDF, HIDF, or HSDF, and a comprehensive multi-omics approach was utilized to assess and compare the effects of these dietary fibers on obesity-related parameters. The results showed that all three dietary fibers significantly reduced body weight, modified blood lipid profiles, and ameliorated tissue damage in HFD-fed mice. Additionally, 16S rRNA sequencing analysis of mice feces showed that three types of dietary fiber exerted varying degrees of impact on the composition and abundance of gut microbiota while simultaneously promoting the biosynthesis of short-chain fatty acids. Specifically, HDF supplementation remarkably enhanced the abundance of Coprococcus , while HIDF and HSDF supplementation elevated the levels of Akkermansia and Allobaculum , respectively. Transcriptomic and proteomic results suggested the PPAR signaling pathway as a central regulatory mechanism influenced by these fibers. HDF and HIDF were particularly effective in modulating biological processes related to triglyceride and fatty acid metabolism, identifying Abcc3 and Dapk1 as potential targets. Conversely, HSDF primarily affected processes related to membrane lipids, ceramides, and phospholipids metabolism, with Pck1 identified as a potential target. Collectively, HDF, HIDF, and HSDF demonstrated distinct mechanisms in exerting exceptional anti-obesity properties. These insights may inform the development of personalized dietary interventions for obesity.

研究领域: 营养学 · 分子生物学 · 微生物学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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FOOD SCIENCE AND TECHNOLOGY RESEARCH · 2023 · IF 0.6

Protective role of polyphenol extract from highland barley against cisplatin-induced renal toxicity and mitochondrial damage in rats

Yunfan Liu,Jiazhou Zhai,Fei Qin,Liping Gao,Yongxin She,Mengqiang Wang

The aim of this study was to investigate the protective effect of polyphenol extract from Highland barley (HBPE) on cisplatin (CDDP)-induced oxidative damage and mitochondrial damage in rat kidney. The experimental rats were divided into control group, CDDP group, HBPE (600 mg/kg) group, CDDP+HBPE (150 mg/kg) group, CDDP+HBPE (300 mg/kg) group and CDDP+HBPE (600 mg/kg) group. Rats in each group were intragastrically fed with normal saline and corresponding dose of HBPE for 21 d. On the 16th day, CDDP group and CDDP+HBPE group were injected intraperitoneally with CDDP (7.5 mg/kg), and the other groups were injected with the same amount of normal saline. On the 22nd day, the rats were killed and blood samples were taken to detect the contents of blood urea nitrogen (BUN) and creatinine (CrE) in serum, and calculate the kidney index. The kidney samples were used for the measurement of malondialdehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), lactate dehydrogenase (LDH), malate dehydrogenase (MDH), hexokinase (HK), and processed for histopathological examinations. The results showed that HBPE improved the abnormalities of serum CrE, BUN, antioxidant and carbohydrate metabolic enzymes in kidney induced by CDDP. HBPE can also reduce the degeneration of renal tubules and glomerular atrophy. Therefore, HBPE has a significant protective effect on oxidative stress injury and mitochondrial damage induced by CDDP in rats.

CAS / MDL: 15663-27-1
研究领域: 药理学 · 毒理学 · 肾病学 · 生物化学
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LIFE SCIENCES · 2023 · IF 6.1

Highland barley attenuates high fat and cholesterol diet induced hyperlipidemia in mice revealed by 16S rRNA gene sequencing and untargeted metabolomics

Xiang Li,Li Wang

Aims In this study, highland barley (HB), HB bran (HBB) and whole grain HB (WGHB) alleviating hyperlipemia and liver inflammation in high fat and cholesterol diet (HFCD) mice was investigated. Methods All 50 ICR mice were randomly allocated to 5 treatment groups: Normal control group, HFCD group, HB group, HBB group and WGHB group. The serum lipid profiles, liver and epididymal adipocyte histology, gut microbiota and untargeted metabolomics were adopted. Key findings The results suggested that HB especially HBB supplement could obviously decrease BW and BWG. Serum lipid profiles showed that HB especially HBB decreased TG , TC, LDL-C, ALT and AST levels while increased HDL-C level. Liver and epididymal adipocyte H&E staining also confirmed that hepatic injury and adipose accumulation were alleviated by HB especially HBB. Gut microbiota analysis indicated that HBB increased Bacteroidetes/ Firmicutes ratio, Lactobacillus and Akkermansia muciniphila abundances while decreased Proteobacteria and Shigella abundances. Untargeted metabolomics results showed that HBB significantly increased deoxycholic acid levels compared with HFCD mice and HBB regulated arachidonic acid metabolism pathway. Significance The obtained results provided important information about the processing of highland barley to retain its hypolipidemic effect and improve its acceptability and biosafety, and had a guiding effect on the development of HB products.

研究领域: 营养学 · 微生物学 · 代谢组学
✓ 已验证 DOI PubMed 高影响因子
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JOURNAL OF CEREAL SCIENCE · 2022 · IF 4.075

Effects of hypoxia stress germination on nutrients, physicochemical properties and cooking characteristics of highland barley

Yan Du,Zhengxing Chen,Feng Liang,Wenju Zhou,Tingyu Li,Zhaoxin Tu,Youjin Tan,Juan Li

The aim of this study was to explore the impact of hypoxia stress germination on qualities of highland barley (HB). The main functional components, physicochemical properties, and cooking qualities of HB were investigated after hypoxia stress germination. Results showed that γ-aminobutyric acid, total phenols, total flavonoids , essential amino acids , and fragrance components of HB were significantly increased ( P  < 0.05) after germination. The relative crystallinity, pasting viscosity, breakdown, setback and enthalpy of hypoxia stress germinated highland barley was decreased as compared to ungerminated HB. However, gelatinization temperature, onset temperature, peak temperature and conclusion temperature of HB increased after germination. The micro-cracks presented on the surface of kernel might be the main reason for improvement of cooking characteristics of HB. To conclude, hypoxia stress germination improved the functional nutrients, physicochemical properties, texture, flavor and taste of HB, which might be an effective method to improve the cooking and edible quality of whole grains .

研究领域: 食品科学 · 植物生理学
✓ 已验证 DOI 高影响因子
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