DESALINATION
·
2025
·
IF 9.8
Shiqiang Liang,Wenbin Wang,Tongyao Wu,Jinkai Zhang,Qindong Wang,Shu Bi,Fan Yang,Chi Wang,Zhi Geng,Zhongmin Su
Nanofiltration (NF) membrane technology, distinguished for high separation performance and energy efficiency, has been extensively employed in desalination and wastewater treatment. Herein, high-precision 3D printing is used to fabricate robust support layers featuring ideal straight-through micropores, effectively minimizing permeation resistance. To ensure the generation of a high-quality PA selective layer, electrospinning deposits a thin nanofiber layer that divides the support layer surface into fine grids. Finally, interfacial polymerization (IP) forms a PA selective layer on the membrane substrate, which is integrated by 3D-printed support layer and nanofiber layer, yielding a highly permeable composite NF membrane. With reduced permeation resistance and enhanced mechanical strength, the novel 3D-printed composite NF membrane maintains a long-term water permeance of above 22.5 L m −2 h −1 bar −1 , about double that of commercial NF270 membranes. Meanwhile, it achieves exceptional Na 2 SO 4 rejection of 97.8 % and superior anti-fouling performance. This study offers a promising approach to fabricating high-performance NF membranes using high-precision 3D printing, providing an innovative and scalable strategy for developing next-generation functional membranes.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
SENSORS
·
2019
·Vol. 19
·期 11
·2442
·
IF 3.031
Jianpeng Zhang,Yuhang Li,Yufeng Xing
Epidermal electronic sensors (EESs) possess great advantages in the real-time and enduring monitoring of human vital information compared to the traditional medical device for intimately making contact with human skin. Skin strain is a significant and effective routine to monitor motion, heart rate, wrist pulse, and skin growth in wound healing. In this paper, a novel skin sensor combined with a ternary conductive nanocomposite (Carbon black (CB)/Decamethylcyclopentasiloxane (D5)/Silbione) and a two-stage serpentine connector is designed and fabricated to monitor skin strain. The ultrasoft (~2 kPa) and adhesive properties of the ternary conductive nanocomposite ensure the capacity of the EES to intimately couple with human skin in order to improve accuracy with a relative error of 3.39% at strain 50% as well as a large strain range (0~50%) and gauge factor (GF ~2.5). The millimeter scale EES (~5 mm × 1 mm × 100 μm), based on the micro-nano fabrication technique, consisted of a two-stage serpentine connector and screen print of the ternary conductive nanocomposite. EESs with high comprehensive performance (electrical and mechanical properties) are fabricated to confirm the analytical results and monitor the motion of a human hand. The good agreement between experimental and analytical results paves the way for bettering monitoring of skin growth during wound healing in order to avoid necrosis and scarring. This EES in monitoring the motion of a human exhibit presents a promising application for assisting prosthetic movement.Keywords:epidermal electronic sensors;skin strain;high accuracy;millimeter scale
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Chu Cheng,Qingzhou Cheng,Wei Zhou,Yulong Chen,Wenbin Liu,Zhiling Zhang,Jingsi Ye,Pengfeng Xiao
Eliminating errors in next-generation sequencing has proven to be challenging. Here we present a novel strategy for DNA sequencing, called correctable two-color fluorogenic DNA decoding sequencing, which can significantly improve sequencing accuracy and throughput by employing a dual-nucleotide addition combined with fluorogenic sequencing-by-synthesis (SBS) chemistry. This sequencing method involves introducing a mixture of natural nucleotide X, labeled unblocked nucleotide X′, 3′ blocked nucleotide Y*, and labeled 3′ blocked nucleotide Y* into each reaction cycle. By cyclically interrogating a template twice with different nucleotide combinations, two sets of base-encoding are sequentially obtained, enabling accurate deduction of base sequence. We demonstrate the remarkable efficacy of this approach in detecting and correcting sequencing errors, achieving a theoretical error rate of 0.0005%, which is twice as accurate as Sanger sequencing. Furthermore, we show the capability to detect known mutation sites using information from only a single sequencing run. The correctable two-color fluorogenic DNA decoding sequencing approach should enable accurate identification of extremely rare genomic variations in diverse applications in biology and medicine.
研究领域:
分子生物学
·
基因组学
·
医学遗传学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2024
·
IF 11.2
Mei-Ling Yang,Guo-Xiang Zhou,Ning Xie,Kun-Peng Lin,Yan-Zhao Zhang,Zhe Zhao,Yun-Peng He,Yu-Hang Zhang,Zhi-Hua Yang,De-Chang Jia,Yu Zhou
Electronic 3D printing possesses a remarkable molding ability and convenience in integrated circuits, flexible wearables, and individual automobile requirements. However, traditional 3D printing technology still struggles to meet the demands of high precision and high efficiency in the process of fabricating a curved surface circuit, particularly achieving precise silver circuit molding on irregular substrates. Here, a high-precision and muti-scaled conformal manufacturing method for silver circuits is presented through the digital light processing (DLP) of ultraviolet-curable silver paste (UV-SP) with adjustable photocuring properties, enabling the successful preparation of micro-scaled conductive structure on the sharply skewed hook face. The minimum modeling depth and width of the cured silver paste can be well controlled to 10 and 88 µm, respectively. Compared with traditional printing technology, the printing efficiency of complex patterns has increased by over 70 %. The printed silver circuit demonstrates an exceptionally high electrical conductivity, reaching as high as 1.16 × 10 7 S/m. Additionally, the UV-SP exhibits significant manufacturing efficiency and superior molding resolution compared to conventional direct ink writing and inkjet printing techniques, thereby contributing to the attainment of high precision and efficiency of conformal and micro-molding manufacturing in sensors, communication antennas, and other electronic devices based on curved substrates.
研究领域:
电子制造
·
材料科学
·
3D打印技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2024
·
IF 6.2
M. Irfan Hussain,Min Xia,Xiao-Na Ren,Changchun Ge,Yunsong Zhao,Zhen Shen
High-precision microfabrication of functional ceramics with complex shapes and tailored properties currently arouse significant attention, but maintaining dimensional accuracy is still a research challenge. Herein, an innovative digital light processing (DLP) 3D technology is employed to fabricate calcined kaolin (Al 2 O 3 ·2SiO 2 ) ceramic with intricate structures, achieving high precision and densification. To illustrate the potential of different solid content slurries (43, 45, 46.2, and 47.5 vol%), and the curing thickness with tuned exposure time (8s, 10s, and 12s), we investigated their impact on physical properties and microstructures. The results show that the optimal sintering at 1200 °C achieved an exceptionally high density 2.38 g/cm 3 , with low shrinkage (17.35 %) along XY-direction and porosity reaching up to 15.53%. The highest level of solids slurry at 47.5 vol% increased the densification and open porosity. For all solid contents, the shrinkage along the Z-direction was exceeded compared to the XY-direction. A comprehensive evaluation of sintered morphologies, including their topography and chemical composition. The EDX mapping showed that kaolin ceramics have excellent stability at high temperatures. The highest flexural strength of DLP printed specimen at temperature (1200 °C) is 71.60 MPa, whereas that of the diamond porous structure is 6.66 MPa. Our work sheds light on high-precision microfabrication of complex shapes with unparalleled accuracy and efficiency, paving the way for high-performance functional ceramic materials.
研究领域:
材料科学
·
陶瓷工程
✓ 已验证
产品关联
DOI
高影响因子
Nano Research
·
2024
·Vol. 17
·期 6
·5595-5603
·
IF 9.5
Zhou Runhui,Huang Jiaoya,Li Zemin,Wang Yushu,Chen Ziyu,Pan Caofeng
Stretchable hybrid systems have been attracting tremendous attention for their essential role in soft robotics, on-skin electronics, and implantable devices. Both rigid and soft functional modules are typically required in those devices. Consequently, ensuring stable electrical contact between rigid and soft modules is a vital part. Here, we propose a simple, universal, and scalable strategy for the stretchable hybrid system through a highly precise printable liquid metal particle-based conductor and adhesive fluorine rubber substrate. The properties of liquid metal particle-based conductors could be easily tuned to realize high-precision patterning, large-scale printing, and the ability to print on various substrates. Additionally, the fluorine rubber substrate could form strong interfacial adhesion with various components and materials through simply pressing and heating, hence enabling stable electrical contact. Furthermore, we prepared a stretchable hybrid light-emitting diode (LED) display system and employed it in on-skin visualization of pressure levels, which perfectly combined rigid and soft modules, thus demonstrating the promising potential applications in complex multifunctional stretchable hybrid systems for emerging technologies.
研究领域:
材料科学
·
柔性电子
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 45
·24928-24938
·
IF 11.9
Zhihao Yang,Ying Yuan,Bin Wang,Xiaojun Shen,Xiluan Wang,Tong-Qi Yuan
In recent years, flexible electronics have developed rapidly in wearable and intelligent devices. There are still great challenges in the development of high-precision flexible strain sensors. Here, an ultra-precise strain sensor of solely biobased materials was realized by a surface graphitization strategy, which cleverly gives the biobased film excellent conductivity to ensure the original flexibility. The strain sensors have an ultra-precise response (gauge factor of 46.65 and linear fitting R2 as high as 0.99903) and high tensile strength (1.2 MPa). The as-assembled strain sensors can not only accurately detect human body movement, but also be completely dissolved in water after use. The green, precise strain sensors have enabled application cases of human–computer interaction and the internet of things and have great development prospects in the field of intelligent applications. This will promote the development of biobased materials in the fields of flexible electronics and human–machine interaction in ultra-precise sensing.
研究领域:
材料科学
·
柔性电子
·
生物工程
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Yaming Liu,Chen Zhang,Youyou Chen,Rui Yin,Peng He,Weiwei Zhao
Highly sensitive and conformal sensors are essential for the implementation of human–machine interfaces, health monitoring, and rehabilitation prostheses. The proper adjustment of conductive pathways in the sensing materials is essential for their sensitive transduction of mechanical stimuli into electrical signals. However, the rational, precise, and wide-range control of electrical networks within traditional conductive composites is difficult due to the randomly distributed fillers. Herein, we adopt an indirect 3D-printing method to fabricate pressure sensors with various microchannels for liquid metal (LM) to form consistent and tunable conductive pathways. LM is highly conductive, fluidic, and incompressible at ambient conditions, which guarantees the reliable regulation and function of our pressure sensor. Additive manufacturing provides a facile way to construct complicated microchannels with different lengths, different orientations, cross-sectional sizes, depth-width ratios, and shapes, which can effectively modulate the sensitivity and the sensing range. Under the optimized structural configurations, our sensor achieves a high sensitivity of 1.139 kPa–1, a detection range of 0–68 kPa (loading process), and stability of over 5000 cycles, whose sensing performance is better than most microchannel-filled LM sensors. It can achieve high-accuracy monitoring of pulse, speaking and gestures, and exhibit a full recognition of objects under the assistance of machine learning. This work can provide new ideas on the design of conductive pathways in flexible electronics and expand the application of recyclable LM in human–machine interfaces.
研究领域:
材料科学
·
生物医学工程
·
电子工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-11
·
IF 14.7
Zhou Xuefan,Zhang Jun,Luo Hang,Zhang Yan,Tang Shiyu,Huang Houbing,Yuan Xi,Song Miao,Qi He,Zhang Dou
The trade-off between electrostrain and strain hysteresis for piezo/ferroelectric materials largely restrains the development of high precision actuators and remains unresolved over the past few decades. Here, a simple composition of (Bi 0.5 Na 0.5 ) 1- x /100 Sr x /100 TiO 3 in the ergodic relaxor state is collaboratively designed through the segregated domain structure with the ferroelectric core, local polarization heterogeneity, and defect engineering. The ferroelectric core can act as a seed to facilitate the field-induced nonpolar-to-polar transition. Together with the internal bias field caused by defect dipoles and adjusted through electric field cycling and heat treatment technology, a giant unipolar strain of 1.03% is achieved in the x = 30 ceramic with a low hysteresis of 27%, while the electric-field-independent large-signal piezoelectric strain coefficient of ~1000 pm/V and ultralow hysteresis of <10% can be obtained in the x = 35 ceramic. Intriguingly, the low-hysteresis high strain also exhibits near-zero remnant strain, excellent temperature and cycling stability.
研究领域:
材料科学
·
电子工程
✓ 已验证
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2017
·
IF 6.32
Huixia Di,Huiqiao Liu,Mingmin Li,Jin Li,Dingbin Liu
Precise profiling of the sialic acid (SA) expression on the membrane of cancer cells is critical for early identification of cancers and assessment of cancer metastasis. However, the complex physiological environments often result in false positives with currently available imaging technologies. Herein, we have established a background-free surface-enhanced Raman scattering (SERS) imaging platform that allows high-precision profiling of SA expression in cancer cells and differentiation of clinically relevant cancer tissues with various metastasis degrees. Three-dimensional Raman imaging technique provided a deeper insight into visualizing the probe distribution and thus the SA expression at the single-cell level, without destructing the cells. This noninvasive, high-precision imaging technique could favor early diagnosis, staging, and monitoring therapeutic responses of cancers that are highly essential in clinical settings.
研究领域:
生物医学
·
分子影像学
·
癌症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Anqi Yang,Yan Huang,Songbao Fu,Haodong Zhang,Sailing He
A high-precision pH monitoring system over a wide pH range is introduced. The system comprises a cavity-enhancement module constructed by two high-reflectivity mirrors, a microfluidic pH sensing chip based on a binary-indicator membrane of Congo red and m-cresol purple, and a hyperspectral transmission module. This structure extends the effective absorption optical path of the sensing chip, significantly amplifying the spectral differences at various pH values. The spectrum of the transmitted light is recorded by a self-developed hyperspectral module and then converted to broadband cavity-enhanced absorption spectrum (BBCEAS) via the Beer-Lambert law. An artificial neural network (ANN) is employed to predict pH values of the solution. With such a design, this system exhibits a wide detecting range of 2 M [H + ] − 2 M [OH – ] (corresponding to pH −0.3–14.3) with a response time of about 120 s. The system can achieve a higher detection accuracy with root mean square error (RMSE) of 0.073, as compared to 0.137 without the cavity enhancement. The system also possesses good properties of repeatability, long-term stability, ion resistance, and organic corrosion resistance. These excellent properties make the proposed system a promising candidate technology for harsh environments, such as seawater acidification warning, chemical plant sewage monitoring, and biological sample detection.
研究领域:
分析化学
·
环境科学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
FORENSIC SCIENCE INTERNATIONAL
·
2016
·
IF 1.95
Shisheng Chen,Yanyi Lv,Dian Wang,Xiaojun Yu
Aspartic acid racemization in teeth has been increasingly used to estimate chronological age with a considerably high accuracy in forensic practice. The Chaoshan population in South China is relatively isolated in geography, and has specific lifestyle and dietary inhibits. It is still unknown whether this method is suitable for this population. The aim of this study was to analyze the relationship between chronological age and the d / l aspartic acid ratio in dentin in the third molar tooth of the Chaoshan population. Fifty-eight non-carious third molar teeth (31 mandibles and 27 maxillae), from 58 living individuals of known age (24 males and 34 females), were retrieved. Dentin was extracted from these teeth. The d - and l -aspartic acids in dentins were separated and detected by high performance liquid chromatography (HPLC). Linear regression was performed between the d / l aspartic acid ratio of dentins and chronological age. Results showed that the correlation coefficient (r) was 0.969, and the mean absolute error (MAE) was 2.19 years, its standard deviation (SD) was ±1.53 years, indicating excellent correlation. There was no significant difference in racemization rates of dentin between sexes ( P = 0.113, F = 2.6), or between mandibles and maxillae ( P = 0.964, F = 0.000). Results indicate that the ratio of the d and l forms of aspartic acid of dentins, in the third molar, is closely correlated with chronological age, special lifestyle do no obviously affect the accuracy of the age estimations by aspartic acid racemization of the dentin in the third molar and that aspartic acid racemization in the third molar dentin can be used as an accurate method to estimate chronological age in the Chaoshan population in South China.
研究领域:
法医学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）