JOURNAL OF PHYSICAL CHEMISTRY B
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2024
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IF 2.8
Xiufeng Zhang,Xiaoying Ma,Buyue Zhang,Dawei Yang,Ruiyang Bai,Yuexing Gao,Hongxia Sun,Yalin Tang,Lei Shi
Viscosity, at the subcellular level, plays a crucial role as a physicochemical factor affecting microenvironment homeostasis. Abnormal changes in mitochondrial viscosity often lead to various diseases in the organism. Based on the twisted intramolecular charge transfer mechanism, four hemicyanine dye fluorescent probes (HT-SA, HT-SA-S, HT-Bzh, and HT-NA) were designed and synthesized for viscosity response. The single bond between the nitrogen-containing heterocycle and the carbon–carbon double in the structure of the probe bond served as the viscosity response site. Finally, the probe HT-Bzh was screened as the optimal mitochondrial viscosity probe according to its responsiveness, targeting, and interference resistance. The fluorescence intensity of the probe HT-Bzh increased 22-fold when the viscosity was increased from 13.75 to 811.2 cP. In summary, all four viscosity probes we have developed can be used in different applications depending on the external environment, providing a valuable reference for the design of potential tools to address viscosity monitoring in biological systems.
研究领域:
化学
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生物学
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材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2020
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IF 5.065
Yu Dong,Tiantian Ping,Xiaoqin Shi,Shufeng Shen
Nonaqueous amine-based blends have great potential for energy-efficient CO 2 absorbent. In this work, densities and viscosities were measured for liquid binary mixtures of 2-(ethylamino)ethanol (EAE) and 2-(butylamino)ethanol (BAE) with 2-butoxyethanol (EGBE) at temperatures of (293.15–353.15)K over the entire concentration range and atmospheric pressure. Intermolecular interactions between EGBE and two secondary amines with different carbon chain length were discussed. The excess molar volume ( V E ), viscosity deviations ( ∆η ) and excess Gibbs free energy ( ∆G ⁎ E ) were calculated from the experimental data and also correlated with the Redlich-Kister equation to estimate the binary interaction parameters. The experimental data and the calculated from the proposed correlations for the studied binary mixtures matched well each other, with AADs within 0.01% and 1.45% for density and viscosity respectively. The variation of excess properties was also discussed in terms of intermolecular interactions. Weak interactions on mixing these binary mixtures with different mass fractions were observed from the FTIR spectra analysis.
研究领域:
化学工程
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热力学
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流体物理化学
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气体吸收
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分离科学
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2021
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IF 4.098
Lingling Zhang,Mengwen Yi,Shilong Zhong,Jing Liu,Xiangjun Liu,Tao Bing,Nan Zhang,Yongbiao Wei,Dihua Shangguan
Viscosity of cell microenvironment plays a significant role in maintaining the normal life activities of cells. Particularly, the abnormal viscosity in mitochondria is closely associated with lots of diseases and cellular dysfunctions. Herein, we developed a group of p-aminostyryl thiazole orange derivatives with different amino side chains. These probes showed good fluorescence response to viscosity with twisted intramolecular charge transfer mechanism, among them, the probes with diethylamino ( TOB ), dibutylamino ( TOC ) and pyrrolidin ( TOE ) side chains showed better response to the viscosity with 78-fold, 55-fold, and 88-fold fluorescence enhancement in 95% glycerol solution respectively. TOB , TOC , and TOE could enter live cells and mainly located in mitochondria. Treatment HeLa cells with nystatin, lipopolysaccharide or oleic acid caused significant fluorescence enhancement of these probes, suggesting the good potential for monitoring the variation of mitochondrial viscosity, as well as for investigating the related physiological process of inflammation and lipid metabolism.
研究领域:
细胞生物学
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生物化学
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分子生物学
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药理学
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产品关联
DOI
PubMed
高影响因子
LANGMUIR
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2024
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IF 3.7
Mingwei Zhao,Ying Li,Caili Dai,Yingpeng Chen,Ziteng Yang,Kaiwen Liu,Zhenfeng Ma
Hydrolyzed polyacrylamide (HPAM) is commonly used in polymer flooding, however, it is prone to viscosity reduction at high temperatures and high salinities, weakening its ability to improve oil recovery. In this work, sulfonated modified silicon quantum dots (S-SiQDs) were synthesized and then added to HPAM to study the improvement of rheological properties and enhanced oil recovery performance of HPAM at high temperatures and salinities. It is found that the S-SiQDs with a concentration of only 0.1 wt % can significantly increase the viscosity of HPAM from 28.5 to 39.6 mPa·s at 60 °C and 10,000 mg/L NaCl. Meanwhile, the HPAM/S-SiQDs hybrid solution always possessed higher viscosity and viscoelastic moduli than HPAM, attributed to the hydrogen bonding between HPAM and S-SiQDs. Notably, HPAM/S-SiQDs still maintained elastic behavior at harsh conditions, indicating that they formed a strong network structure. Through oil displacement experiments, it was found that the oil recovery of HPAM/S-SiQDs was higher (28.3%), while that of HPAM was only 17.2%. Thereafter, the utilization sequence of oil during the displacement process was studied with nuclear magnetic resonance experiments. Ultimately, the oil displacement mechanism of HPAM/S-SiQDs was deeply analyzed, including viscosity thickening and wetting reversal.
研究领域:
石油工程
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材料科学
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化学工程
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
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IF 6.953
Yao Li,Maolan You,Haibo Liu,Xiong Liu
Highland barley grains were roller-milled to produce five different fractions (B-1, B-2, B-3, B-4, and B-5). The distribution and physicochemical properties of β-glucans from five roller-milled fractions were investigated. The B-4 fraction contained the highest concentration of β-glucan (4.40%), and the outermost bran (B-1) had the lowest β-glucan content (1.01%). Besides, β-glucans from inner core B-5 (BG-5) had higher M w (6.482 × 10 5 g/mol), whereas β-glucans from outer bran B-1 (BG-1) showed lower M w (5.859 × 10 4 g/mol) than those from other fractions. Accordingly, the viscosity of BG-5 was highest (0.038-0.365 Pa·s), and the water solubility index of BG-1 was highest (50.43–90.71%). BG-5 showed stronger foam stability and emulsifying properties but weaker foaming capability, while BG-1 exhibited stronger foaming capability. The foaming capability and emulsifying properties of β-glucan samples were better under the neutral condition (pH = 7). The foam capabilities of all β-glucan samples displayed higher values at 65 °C, and emulsifying properties exhibited higher values at 45 °C. This study is expected to promote the application of highland barley β-glucans in food industry.
研究领域:
食品科学
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植物化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2017
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IF 2.323
Yingying Shan,Behnaz Asadzadeh,Weidong Yan
Thermophysical properties including densities and viscosities of naringenin in aqueous solutions of ethanol/1-propanol with alcohol concentrations of (24.00 to 40.00) mol·kg–1 have been measured as a function of concentration of naringenin at temperatures from (293.15 to 323.15) K and atmospheric pressure. Also, refractive indices for studied systems have been determined at 298.15 K. The measured data were used to calculate the apparent molar volume (Vϕ), standard partial molar volume (Vϕ0), partial molar volume (V̅), viscosity B-coefficients, and molar refractions (Rm). The viscosity and refractive index data have been analyzed by Jones–Dole and Lorentz–Lorenz equations, respectively. The trends of variation of experimental and calculated parameters have been discussed according to the interactions between solvents and solute. The obtained results imply that naringenin acts as a structure maker in the studied system.
研究领域:
物理化学
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药物化学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
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2014
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IF 3.259
Jianyong Wu,Jun Chen,Wei Liu,Chengmei Liu,Yejun Zhong,Dawen Luo,Zhongqiang Li,Xiaojuan Guo
Understanding how aleurone layer (AL) affects rice cooking behaviour is important for rice processing. Individual effects of AL on rice cooking behaviour were evaluated and histological characters of AL before and after cooking were investigated. AL slightly affected rice cooking quality (optimum cooking time, water absorption, volume expansion ratio and total solids loss) while remarkably affected rice texture (hardness and adhesiveness) and peak viscosity. Histological investigation showed that channels were formed in AL during cooking. The channels facilitated the penetration of water, which could explain why AL exhibited slight effects on rice cooking quality. In addition, thick cell walls and thermally stable aleurone grains were widely distributed in AL. Leached components accumulated on them and formed a reinforced coated film on rice surface during cooking, which may be a possible mechanism accounting for the remarkable effect of AL on rice texture. Histological characters of AL are closely related with rice cooking behaviour.
研究领域:
食品科学
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植物解剖学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Jiawu Wu,Yingjiao Tang,Wenxue Chen,Haiming Chen,Qiuping Zhong,Jianfei Pei,Tao Han,Weijun Chen,Ming Zhang
In this study, monosodium glutamate (MSG) was used to improve the viscosity of coconut milk and the underlying mechanism was explored by investigating the changes in structures of coconut milk protein and physicochemical properties of coconut milk. Firstly, the effect of MSG on the properties of coconut milk was studied. The results showed that MSG increased the pH and zeta potential , reduced the particle size, thus enhancing the droplet interaction and increasing the viscosity of coconut milk. Subsequently, the effects of MSG on the structure and properties of coconut proteins (CP) were investigated. FTIR spectroscopy and circular dichroism spectroscopy showed that MSG was able to change the secondary structure of CP. The results of SDS-PAGE showed that MSG was able to bind to CP to form a larger molecular weight protein, thus improving the viscosity of coconut milk. Moreover, MSG was also able to increase the water-binding capacity of CP. In addition, molecular docking and driving force analysis revealed that hydrogen bonds , electrostatic forces, disulfide bonds , and hydrophobic interactions are the main interactions between MSG and CP. Studying the effect of MSG on the viscosity of coconut milk provides theoretical support to improve the viscosity of other plant protein emulsions.
研究领域:
食品科学
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蛋白质化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2015
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IF 2.037
Daofan Ma,Xiaofeng Jiang,Guoqiang Wei,Chunying Zhu
The densities and viscosities of glycine, l-alanine, l-valine, l-threonine, and l-arginine in (0.1 to 0.4) mol·kg–1 vitamin B6 aqueous solutions were measured and studied over the entire molality range at (293.15, 303.15, 313.15, and 323.15) K and atmospheric pressure. The apparent molar volume (Vϕ), limiting partial molar volume (Vϕ0), and limiting partial molar volume of transfer (ΔtrVϕ0) were obtained according to the experimental density data. The viscosity data were employed to determine the viscosity B coefficients, the free energies of activation per mole of solvent (Δμ10⇌) and solute (Δμ20⇌). The influences of temperature, molality, and solute structure on these parameters were discussed in terms of molecular interactions. The contributions of the charged end group (NH3+, COO–) and CH2 group to the limiting partial molar volumes and viscosity B coefficients were obtained through their linear correlation as a function of the number of carbon atoms in the alkyl chains of the studied amino acids.
研究领域:
生物化学
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物理化学
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产品关联
DOI
高影响因子
Food Chemistry-X
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2025
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IF 8.2
Xilu Zhang,Yongxia Fu,Han Wang,Qun Shen,Zhenyu Liu,Yuanlong Chi
The effect of deproteinized Tremella olysaccharide (DTP) on the in vitro digestion of potato starch (PS) was investigated. DTP reduced the hydrolysis rate of PS in a concentration-dependent manner, with digestion rates of 76.99 %, 72.03 %, and 29.73 % after 180 min for 0.3, 0.6, and 1.2 mg/mL DTP, respectively. DTP delayed digestion by shifting the kinetics from single-phase to biphasic behavior. It significantly inhibited pancreatic α-amylase (IC 50 = 5.76 mg/mL) by modifying the enzyme's secondary structure and reducing substrate binding. Additionally, DTP enhanced digesta viscosity, which may have contributed to the reduction in postprandial glucose release, thereby supporting its role as a potential hypoglycemic agent. However, DTP exhibited minimal glucose adsorption, binding only 1.2 % of 100 mM glucose at 1.2 mg/mL. These findings suggest that DTP reduces starch digestion primarily by inhibiting α-amylase activity and increasing digestive viscosity, providing insights into its hypoglycemic potential.
研究领域:
食品科学
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生物化学
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药理学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2019
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IF 4.561
Weibiao Du,Xiaopo Wang
In this work, the volumetric and viscometric properties of the mixtures of methyl decanoate with 1-propanol, 1-butanol, and 1-pentanol were investigated from 298.15 K to 333.15 K. The density data of the mixtures were obtained based on the vibrating-tube densimeter , and the kinematic viscosities of the mixtures were measured using the Ubbelohde capillary viscometer . Based on the experimental data, the excess molar volumes and viscosity deviations were calculated and correlated with the Redlich–Kister equation. In addition, the McAllister four-body model, Frenkel model, Grunberg-Nissan model, and Heric's model were used to correlate the viscosities of the mixtures.
研究领域:
物理化学
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热力学
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流体性质
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燃料化学
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溶液化学
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DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2021
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IF 6.165
Tao Yang,Yukun Sun,Xianyang Meng,Jiangtao Wu,J. Ilja Siepmann
This work reports new experimental data for the density and viscosity of n -decane + CO 2 binary mixtures. A simultaneous density and viscosity measurement apparatus was redesigned using a vibrating–wire viscometer coupled with a vibrating–tube densimeter. The measurements for the pure component ( n -decane) and three different binary mixtures ( n -decane + CO 2 ), with mole fractions of n -decane of (0.4026, 0.2225, 0.1262), were carried out at temperatures ranging from (303.15 to 373.15) K and pressures up to 80 MPa. The expanded relative uncertainties ( k = 2, level of confidence = 0.95) were estimated to be 0.2% for density and 3.0% for viscosity over the entire measurement range, respectively. Densities were correlated as a function of temperature and pressure through a modified Tait–type equation with an average absolute percentage deviation less than 0.05%. To model the viscosity of the binary mixtures as a function of temperature, density, and composition, the extended hard–sphere method combined with simple quadratic mixing rules were used to describe our experimental data. Good agreement is found between experiments and correlations, which attests to the predictive capabilities of semi–empirical equations. In addition, Monte Carlo simulations in the isobaric-isothermal ensemble with the Transferable Potential for Phase Equilibria–United Atom (TraPPE–UA) force field were carried out to characterize the microscopic structure of the studied systems.
研究领域:
化学工程
·
流体力学
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DOI
高影响因子
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