CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Huilan Zhuang,Lun Wang,Sijie Shao,Haitong Jing,Panpan Xue,Tingjie Bai,Jinpeng Deng,Xuemei Zeng,Xian Qin,Shuangqian Yan
Ferroptosis has emerged as a novel approach to suppress tumor growth through the iron-dependent accumulation of lipid peroxides, providing new opportunities for cancer therapy. However, the effectiveness of ferroptosis is impeded by the substantial neutralization of reactive oxygen species (ROS), generated through the Fenton reaction, by the high level of glutathione in cancer cells. Here we report a titanium metal–organic frameworks (MOFs)-derived method to create black TiO 2 nanoparticles with excellent photocatalytic performance. The nanoparticle has a narrow bandgap of 1.02 eV, multiple discrete gap states, and a high density of oxygen vacancies (46.2 %), facilitating ROS generation under 1064-nm light irradiation. When coated with a tannic acid/Fe 3+ layer, the resulting nanocomposite possesses the ability to deplete glutathione concentration, preventing the newly generated ROS from being neutralized and promoting ferroptotic cancer cell death. Complemented by photothermal and chemodynamic effects, in vivo experiments demonstrate a high tumor inhibition rate of 89.8 %. The utilization of MOF-derived nanomaterials represents a universal strategy, offering a solution for ferroptosis-based therapy in solid tumors and contributing to the development of smart, optically active materials with diverse applications in biological contexts.
研究领域:
生物医学
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材料科学
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肿瘤学
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 24
·10399-10411
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IF 3.553
Yang Wangyang,Shen Honglie,Min Huihua,Ge Jiawei
The application of TiO 2 acetone monitor is highly limited by the high operating temperature and poor sensitivity. In this work, black TiO 2 (B-TiO 2 ) is produced by Ti 3+ self-doping and is followed by Ag modification to form B-TiO 2 @Ag. It is first demonstrated that the operating temperature and sensitivity of TiO 2 to acetone can be promoted evidently. By introducing a Ti 3+ self-doped layer on the surface of TiO 2 , as observed in TEM images, the band gap of TiO 2 is reduced to 3.01 eV. Ag surface decoration is carried out for the enhancement of electron generation. Optical absorption and the Hall effect results prove that B-TiO 2 @Ag exhibits highest photoelectrical properties. As a result, the B-TiO 2 @Ag gas sensor with a low operating temperature at 250 °C and high response of 68.19 to 50 ppm acetone is realized. The low detection limit of B-TiO 2 @Ag sensor reaches 887 ppb, which provides an applicable way for non-invasive detection of blood glucose.
研究领域:
材料科学
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传感技术
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生物医学工程
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DOI
高影响因子
ELECTROCHIMICA ACTA
·
2020
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IF 6.215
Tong Wu,Guiru Sun,Wei Lu,Liping Zhao,Alain Mauger,Christian M. Julien,Liqun Sun,Haiming Xie,Jinghai Liu
The inhibition of the shuttle of lithium polysulfides (LiPSs) and enhancement of the electrical conductivity of the cathodes are desirable to improve the performance of lithium-sulfur batteries. In the present work, we report a cathode acting simultaneously as a highly efficient LiPSs immobilizer and sulfur host. It is composed of sulfur embedded inside a hollow sphere, the shell of which is made of hollow black TiO 2 (b-TiO 2 ) spherical nanoparticles . The particles of the composite are then coated with a polypyrrole (PPy) layer to form the active cathode element (b-TiO 2 /S@PPy). The particular topology of the b-TiO 2 layer provides enough space to alleviate the volume expansion of LiPSs. Equally, the PPy coating layer can not only improve the conductivity of the cathodes, but also restrain the shuttle of LiPSs by chemical adsorption . With the sulfur content of 59.6 wt% corresponding to a sulfur loading of 1.5–1.8 mg cm −2 , the lithium-sulfur batteries with the b-TiO 2 /S@PPy cathode exhibits a high initial discharge capacity (1374 mAh g −1 at 0.1C), a superior cycling stability (910 mAh g −1 after 200 cycles at 0.1C), and a good rate performance (725 mAh g −1 at 2C).
研究领域:
材料科学
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能源存储技术
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
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2022
·Vol. 33
·期 27
·275712
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IF 3.953
Yangchun Feng,Wangyang Yang,Yufang Li,Honglie Shen
In recent years, high-performance acetone gas sensors have attracted great attention for their potential in noninvasive blood glucose monitoring. In this work, black TiO2 (B-TiO2) was introduced as an electron trapping layer between TiO2 and ZnO to form TiO2@B-TiO2@ZnO core–shell nanoparticles, through a simple and safe method. The acetone sensing performance of TiO2@B-TiO2@ZnO varied with the thickness of ZnO. Because of the electron trapping effect of the introduced B-TiO2 layer, the best performing sample exhibited a low optimal operating temperature of 275 °C and a high response of 49.25–50 ppm acetone. In addition, a low detection limit of 170 ppb was obtained. The pretty selectivity of the sample was also been proved. The mechanism of enhanced acetone response was explained by the energy band-based model of TiO2@B-TiO2@ZnO core–shell nanoparticle and depletion layer theory.
研究领域:
材料科学
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传感技术
✓ 已验证
DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
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2017
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IF 4.164
Wenjun Ni,Meng Li,Jiayi Cui,Zipeng Xing,Zhenzi Li,Xiaoyan Wu,Erlin Song,Mancheng Gong,Wei Zhou
The black TiO 2 nanoparticles are synthesized via a facile calcination method combined with an in-situ controllable solid-state reaction approach. The results indicate that the photocatalyst with a narrow band gap of ~ 2.32 eV extends the photoresponse to visible light and near infrared region. And thus more reactive oxygen species can be obtained to induce the cell-killing under 808 nm light triggering. The as-obtained black TiO 2 nanoparticles exhibiting low toxicity, good biocompatibility and high anticancer effect in vitro, is demonstrated as efficient photosensitizers for phototherapy to kill the bladder cancer cells. These findings suggest that the facile synthetic black TiO 2 nanomaterials will have broad application in biomedicine.
研究领域:
纳米技术
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癌症研究
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生物医学工程
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材料科学
✓ 已验证
DOI
PubMed
高影响因子
Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2025
·
IF 4.6
Wenbin Huang,Ningran Hou,Han Yang,Zhen Xu,Tianyu Bai,Fan Shao,Yasong Zhou,Qiang Wei
Series g-C 3 N 4 /Cu/B-TiO 2 (x) composites with different mass ratio of g-C 3 N 4 to Cu/B-TiO 2 were prepared and tested for photocatalytic reduction of CO 2 . The structure–function relationship of the photocatalysts was investigated through various characterization methods and photocatalytic experiments. The results show that g-C 3 N 4 can be uniformly distributed on the surface of Cu/B-TiO 2 and formed a stable heterojunction structure, which effectively reduced the band gap width of the catalyst, thus significantly improving the visible light absorption capacity of the catalyst. The modulation of the composite material properties can be realized by regulating the composite ratio of g-C3N4 and Cu/B-TiO 2 . The rate and selectivity of photocatalytic reduction of CO 2 to produce CO reached the maximum when the mass ratio of g-C 3 N 4 to Cu/B-TiO 2 was 3:7, and the rate of CO production was as high as 32.65 μmol∙g −1 ∙h −1 , which was about 12.87 percentage points higher than that of Cu/B-TiO 2 .
研究领域:
材料科学
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光催化
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环境化学
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能源化学
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纳米材料
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 6
·8689-8702
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IF 0
Song Xiaojie,Meng Ying,Zhou Xin,Cheng Kang,Liang Yu,Yang Zhihong
In this work, black TiO 2 (BTiO 2 ) loaded on black red mud (BRM) was successfully prepared with the conversion of Fe 2 O 3 into magnetic Fe 3 O 4 in red mud and the reduction of partial Ti 4+ to Ti 3+ in TiO 2 via the facile sol–gel method and H 2 reduction treatment. The obtained low-cost BRM/BTiO 2 composites exhibit remarkable photocatalytic degradation toward rhodamine B (91.2%) and tetracycline (83.6%) under visible light irradiation, much better than pristine TiO 2 . This enhancement is attributed to the narrow bandgap with the desired solar-light excitation, the black color with good solar-light absorption, and the heterojunctions with the efficient separation of photogenerated electron–hole pairs. Moreover, the desired magnetic separation of BRM/BTiO 2 composites realizes the recycle and recovery of photocatalysts, favoring practical applications in environment. This work provides a cost-efficiency way to prepare RM-supported TiO 2 composites for treating organic pollutants in the wastewater, which is of great significance to the comprehensive utilization of RM waste, the cost saving of the photocatalyst, and the visible-light active enhancement of TiO 2 .
研究领域:
环境科学
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材料科学
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化学工程
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纳米技术
✓ 已验证
DOI
Scientific Reports
·
2017
·Vol. 7
·期 1
·1-11
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IF 4.259
Shen Liyan,Xing Zipeng,Zou Jinlong,Li Zhenzi,Wu Xiaoyan,Zhang Yuchi,Zhu Qi,Yang Shilin,Zhou Wei
Black TiO 2 nanobelts/g-C 3 N 4 nanosheets laminated heterojunctions (b-TiO 2 /g-C 3 N 4 ) as visible-light-driven photocatalysts are fabricated through a simple hydrothermal-calcination process and an in - situ solid-state chemical reduction approach, followed by the mild thermal treatment (350 °C) in argon atmosphere. The prepared samples are evidently investigated by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, N 2 adsorption, and UV-visible diffuse reflectance spectroscopy, respectively. The results show that special laminated heterojunctions are formed between black TiO 2 nanobelts and g-C 3 N 4 nanosheets, which favor the separation of photogenerated electron-hole pairs. Furthermore, the presence of Ti 3+ and g-C 3 N 4 greatly enhance the absorption of visible light. The resultant b-TiO 2 /g-C 3 N 4 materials exhibit higher photocatalytic activity than that of g-C 3 N 4 , TiO 2 , b-TiO 2 and TiO 2 /g-C 3 N 4 for degradation of methyl orange (95%) and hydrogen evolution (555.8 μmol h −1 g −1 ) under visible light irradiation. The apparent reaction rate constant (k) of b-TiO 2 /g-C 3 N 4 is ~9 times higher than that of pristine TiO 2 . Therefore, the high-efficient laminated heterojunction composites will have potential applications in fields of environment and energy.
研究领域:
材料科学
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光催化
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纳米材料
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环境功能材料
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能源材料
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半导体物理
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表面化学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 8
·4302-4309
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IF 11.9
Menghan Yu,Nan Wang,Kuo Lin,Dongxue Song,Jie Chen,Teng Liang,Jianhui Sun,Kai Pan,Honggang Fu
Photocatalytic selective oxidation of benzyl alcohol into benzaldehyde at normal temperature and pressure is one of the important topics in the catalysis field. Here, a lead-free double perovskite Cs2AgBiBr6 nanocrystal/mesoporous black TiO2 composite was prepared by a vacuum-assisted method, and then it was applied for photocatalytic selective oxidation. The photocatalytic oxidation of benzyl alcohol to benzaldehyde was found to occur with 75% conversion and 99% selectivity with the Cs2AgBiBr6 nanocrystal/black TiO2 composite, which were better than those of single Cs2AgBiBr6 nanocrystals and black TiO2, respectively. This was due to the formation of a Z-type heterogeneous structure between Cs2AgBiBr6 nanocrystals and black TiO2, which effectively promoted the separation and transfer of electrons and holes, ultimately leading to excellent photocatalytic activity. During the whole catalytic process, carbon-centered radicals were the key intermediates for the dehydrogenation of benzyl alcohol. This work may provide some practical suggestions for the fabrication of benzyl alcohol selective oxidation photocatalysts.
研究领域:
催化
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材料科学
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化学工程
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2018
·Vol. 7
·期 2
·210-223
·
IF 4.776
Madiha Saeed,M. Zubair Iqbal,Wenzhi Ren,Yuanzhi Xia,Waheed S. Khan,Aiguo Wu
The development of a simplified theranostic system with high-efficiency for multifunctional imaging-guided photodynamic therapy/photothermal therapy (PDT/PTT) is a great challenge. Therefore, a versatile fabrication strategy was introduced to design new Fe3O4-black TiO2 nanocomposites (Fe–Ti NCs). The Fe–Ti NCs exhibit an intense broad light absorption, high photothermal conversion efficiency, inherited phototherapy, and favorable magnetic resonance imaging (MRI) properties. The in vitro results demonstrate synergistic PTT and PDT capability of Fe–Ti NCs under 808 nm irradiation at low concentration and power density. Fe–Ti NCs also show superior phototherapy performance (PTT/PDT) under 671 nm laser irradiation. The confocal microscopy analysis demonstrates reactive oxygen species (ROS)-mediated synergistic phototherapy. Hematological and histological analysis confirms no evident toxicity of Fe–Ti NCs. The in vivo photoinduced tumor ablation capability of Fe–Ti NCs was assessed and monitored, and a rapid increase in temperature (60 ± 2 °C) after being exposed to 808 nm laser at 0.7 W cm−2 for 5 min was observed. Then, the same change in temperature is observed under 671 nm laser at 0.5 W cm−2. Thus, in vitro and in vivo dual-wavelength laser tumor ablation ability of Fe–Ti NCs verified excellent synergistic phototherapy efficacy against tumors. Moreover, Fe–Ti NCs exhibit superparamagnetic behavior, high magnetization value (48 emu g−1), good r2 relaxivity value (38.2 mM−1 s−1), and excellent T2 imaging capability to monitor therapeutic performance.
研究领域:
生物医学工程
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肿瘤学
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纳米医学
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影像医学
✓ 已验证
DOI
PubMed
高影响因子
Biomaterials Science
·
2018
·Vol. 6
·期 8
·2209-2218
·
IF 5.831
Siqi Wang,Wenzhi Ren,Jianhua Wang,Zhenqi Jiang,Madiha Saeed,Lili Zhang,Aiguo Li,Aiguo Wu
At present, transmembrane glycoprotein CD133 highly expressed pancreatic cancer stem cells (PCSCs), with the features of chemotherapeutic/radiotherapeutic resistance and exclusive tumorigenic potential, are considered as the primary cause of metastasis and recurrence in pancreatic cancer, and therefore are an effective target in the disease treatment. Furthermore, with the launch of precision medicine, multifunctional nanoprobes have been applied as an efficient strategy for the magnetic resonance imaging (MRI)-guided photothermal therapy (PTT) of pancreatic cancer. In this research, with the aim of achieving precise MRI-guided PTT in CD133 highly expressed PCSCs, novel bTiO2-Gd-CD133mAb nanoprobes were designed and successfully prepared by loading Gd-DOTA and CD133 monoclonal antibodies on black TiO2 nanoparticles. It was very interesting to find that the r1 relaxivity value of the nanoprobes was 34.394 mM−1 s−1, about 7.5 times that of commercial Magnevist (4.5624 mM−1 s−1), which indicates that the nanoprobes have good potential as MRI T1 contrast agents with excellent performance. Herein, CD133 highly expressed PANC-1 cells were selected and verified as PCSCs model. In vitro experiments demonstrated that the nanoprobes exhibited active-targeting ability in PANC-1 cells, and consequently could specially enhance T1-weighted MR imaging and 808 nm near-infrared (NIR)-triggered PTT efficiency in the PCSCs model. Our study not only provides a new strategy for the effective treatment of pancreatic cancer and its’ stem cells, but also further broadens the application of black TiO2 in the field of cancer theranostics.
研究领域:
癌症研究
·
纳米技术
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医学成像
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诊疗一体化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Energy
·
2022
·Vol. 7
·期 11
·1042-1051
·
IF 67.439
Zhang Lili,Liu Le,Pan Ziye,Zhang Rui,Gao Zhuoyang,Wang Guangming,Huang Keke,Mu Xiaoyue,Bai Fuquan,Wang Yan,Zhang Wei,Cui Zhonghua,Li Lu
Direct non-oxidative dehydrogenation of alkanes produces useful carbon feedstocks and hydrogen fuel. However, breaking the C–H bonds in alkanes typically requires high temperature, stoichiometric oxidants or high-energy ultraviolet light; processes that operate under milder conditions are attractive but tend to have poor efficiency. Here we report Pt/black TiO 2 photocatalysts in which Pt species are close to each other but not directly bonded, exhibiting high performance for alkane dehydrogenation in visible to near-infrared light at room temperature. For cyclohexane dehydrogenation, the turnover number for H 2 production exceeded 100,000 without any deactivation over 80 reaction cycles, far beyond thermal reactions. For methane, 8.2% conversion was achieved with 65% selectivity to propane, rather than the more common ethane. We propose that methane undergoes intramolecular dehydrogenation to produce a methylene intermediate. For C2+ alkanes, fast dehydrogenation (up to 1,440 µmol g −1 h −1 ) to the corresponding olefins was realized. Distinct from isolated Pt + monomers, the collections of Pt + monomers give better photocatalytic activity and selectivity.
研究领域:
化学
·
催化
·
材料科学
·
能源
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）