CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE
·
2009
·
IF 2.976
Chao Yang,Tingmei Wang,Peng Liu,Huigang Shi,Desheng Xue
Composites consisting of conducting polypyrrole (PPy) and fly ash (FA) or amino-functionalized fly ash (A-FA) were prepared by the in situ chemical oxidative polymerization method, respectively. The surface functionalization of fly ash (FA) with amino groups was found to play an important role in the formation of the well-defined blackberry morphology. The scanning electron microscopy (SEM) analysis showed that the well-defined blackberry-like morphology of the polypyrrole/amino-functionalized fly ash (PPy/A-FA) composites with size range of 0.3–5 μm and the surface of the composites became smoother with more A-FA charged in the in situ chemical oxidative polymerization. X-ray diffraction (XRD) analysis of the PPy/A-FA composites showed the similar patterns as FA, which revealed that the crystal structure of FA was well-maintained after the surface functionalization and the in situ chemical oxidative polymerization. Thermogravimetric analysis (TGA) showed that the thermal stability of PPy/A-FA composites was enhanced and this could be attributed to the retardation effect of amine-functionalized fly ashes as barriers for the degradation of polypyrrole. The composites possess high electrical conductivity at room temperature, weak temperature dependence of the conductivity and good magnetic properties .
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2018
·
IF 3.52
Vemana Gowd,Tao Bao,Wei Chen
Beneficial properties attributed to the intake of blackberry fruit are associated with the presence of high content of anthocyanins. However, their low absorption and accumulation in the gut have generated the belief that gut metabolites of anthocyanins are probably reason for their protective effects. In this study, blackberry anthocyanins were prepared and subjected to in vitro human gut microbiota fermentation at different time intervals (0–48 h) to study their gut metabolites and antioxidant properties. The content of cyanidin-3- O -glucoside was found highest in blackberry and it degraded completely after 6 h fermentation. Gut metabolites of blackberry anthocyanins were found to improve the glucose consumption and glycogen content significantly in HepG2 cells. Furthermore, gut metabolites significantly ameliorated high glucose plus palmitic acid (HG + PA)-induced ROS, mitochondrial membrane collapse, and glutathione depletion in HepG2 cells. Overall, this study reveals that blackberry anthocyanins subjected to gut microbiota fermentation resulted in the formation of active metabolites with potential antioxidant activity against HG + PA-induced oxidative stress.
研究领域:
食品科学
·
微生物学
·
营养学
✓ 已验证
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Hao Zhang,Antonio Dario Troise,Yajing Qi,Gangcheng Wu,Hui Zhang,Vincenzo Fogliano
Polyphenols bound to insoluble fibre may scavenge reactive carbonyl species by surface chemical reactions. In the present study, this hypothesis was tested by investigating the ability of bound-polyphenol rich insoluble dietary fibre (BP-IDF) isolated from blackberry pomace, red cabbage, and wheat bran in scavenging carbonyl compounds. Three BP-IDF showed high scavenging efficacy for glyoxal, methylglyoxal, acrolein and malondialdehyde. Upon in vitro digestion, trapping capacity was retained by the insoluble fraction suggesting that carbonyl trapping activity and physiological relevance needs to be extended to undigestible materials. The removal of bound polyphenols from the polysaccharide backbones through alkaline and acidic treatment reduced by up to 90% of trapping capacity of BP-IDF. Moreover, methylglyoxal-polyphenol adducts were detected bound to blackberry pomace BP-IDF after hydrolysis. These findings demonstrated that polyphenols bound to IDF scavenged reactive carbonyl species and highlighted the physiological relevance of BP-IDF in limiting carbonyl stress along all the gastrointestinal tract.
研究领域:
营养学
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食品科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Chenyang Liu,Yuchi Zhou,Weirong Feng,Yuying Wang,Xiaobei Zhan,Yun Jiang,Xiaonan Zhu,Qingyu Wang,Qijun Pan,Liping Xu,Jun Kang,Guoan Zhu,Houjun Xu,Minjie Gao,Zhitao Li
Blackberry seed polysaccharides (BSPs) are commonly considered to be a beneficial living substance. The digestive mechanism and functional properties of BSPs in the human gastrointestinal tract were investigated by simulating chronological digestion and dynamic fermentation in vitro . SEM and FT-IR analyses demonstrated that the dynamic digestion of BSPs resulted in solely morphological changes, with no effect on structural characteristics. The results of the alpha diversity and beta diversity analyses suggested that BSPs had the capacity to enhance the diversity of intestinal microorganisms to a certain extent. In terms of species composition, after fermentation, BSPs led to an increase of 6.3 % and 8 % respectively in the probiotic genera Bacteroides and Bifidobacterium , and a reduction of 3 % in the proportion of the harmful genus Megamonas . In contrast to the control group, BSPs significantly enhanced the production of SCFAs and intestinal gases, which were positively correlated with the composition of intestinal microorganisms such as Smithella and Thermovirga . It was concluded that BSPs have the capacity to induce changes in the structure and composition of the intestinal microorganisms, which in turn leads to the production of beneficial products. This study offers novel concepts for the innovative application of BSPs in the development of functional foods and accumulates significant experience for the development of in vitro simulated digestion and efficacy evaluation of foods.
研究领域:
食品科学
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微生物学
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营养学
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生物技术
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胃肠病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Xuemei Li,Jianxin Gan,Peng Cao,Wenling Guo,Rongmin Wang,Pengfei Song,Yufeng He
The antibacterial materials are rapidly emerging as a primary component in mitigation of bacterial pathogens, and functional polymers play a vital role for the preparation of antibacterial coatings. In this study, using one-pot soap-free emulsion polymerization, we synthesized blackberry-shape cationic copolymer particles (BsCCP) with broad-spectrum antibacterial activity, and the BsCCP emulsion was added to the coating of the interior walls, which afforded BsCCP-based coating (BsCCP-C). The effects of surfactants, initiators, temperature, and monomer ratio on the synthesis of BsCCP were investigated. Besides, BsCCP was characterized by Fourier Transform infrared spectra (FT-IR), scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). The antibacterial activities of BsCCP and BsCCP-C against Escherichia coli and Staphylococcus aureus were evaluated. BsCCP showed positive charge, high specific surface area and rough surface, which presented strong bactericidal activity. Its antibacterial mechanism was also discussed and demonstrated. To sum up, the BsCCP and BsCCP-C with high antibacterial activity showed great potential and was expected to be a candidate of antibacterial coating materials, which are able to use for rapidly and effectively resisting to the bacterial propagation.
研究领域:
材料科学
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生物学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Yuanyuan Rao,Fang Ni,Yun Sun,Benwei Zhu,Zhi Zhou,Zhong Yao
Uniform zeolitic imidazolate framework (ZIF-8) nanoparticles were synthesized then dispersed into a rubbery polydimethylsiloxane (PDMS) matrix to prepare ZIF-8/PDMS hybrid membranes. The performance of the ZIF-8/PDMS hybrid membrane was evaluated in ethanol-water and aromatic-water model systems. The ZIF-8/PDMS hybrid membranes, loaded with 6 wt% of the nanoparticles, separated of ethanol and the characteristic compounds in blackberry juice, linalool, benzaldehyde and ethyl acetate more effectively than a pure PDMS membrane. Based on these results, a ZIF-8/PDMS hybrid membrane was used to separate the volatile aromatic compounds (VACs) from natural blackberry juice. The total volatile aromatic compounds in the blackberry juice decreased significantly after pervaporation treatment. The recovery of linalool, benzaldehyde and ethyl acetate at 50 °C were 93.8%, 92.1% and 75.2%, confirming the high performance of ZIF-8/PDMS hybrid membrane.
研究领域:
化学工程
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材料科学
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食品科学
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2017
·Vol. 9
·期 17
·2535-2545
·
IF 1.9
Jun Sang,Qun Ma,Cui-qin Li
This study was aimed at developing and validating a green HPLC-DAD method to determine anthocyanins using ethanol and an alpha-hydroxy acid aqueous solution as a mobile phase. The effects of alpha-hydroxy acids on the chromatographic behaviors of cyanidin-3-O-glucoside, the most predominant anthocyanin in nature, in a C18 column were investigated. Among seven selected alpha-hydroxy acids, tartaric acid exhibited potential for improving the chromatographic separation of cyanidin-3-O-glucoside. Cyanidin-3-O-glucoside was the main anthocyanin in haskap berry, mulberry, and blackberry, and the three berries were selected for further method development and validation. The optimized mobile phase was a mixture of ethanol and a 0.25 mol L−1 tartaric acid aqueous solution at the 20 : 80 (v/v) ratio. The retention time of cyanidin-3-O-glucoside was less than 1.8 min, and an optimum separation of anthocyanins was achieved in 4 min. The developed method was validated in terms of linearity, limits of detection and quantification, precision, repeatability, stability, and recovery. The calibration curve revealed good linearity (R2 = 0.9999), and the limits of detection and quantification were 0.038 mg L−1 and 0.125 mg L−1, respectively. The relative standard deviations of intra- and inter-day precision, repeatability, and stability were less than 5%. The recoveries of cyanidin-3-O-glucoside from the berry samples were between 99% and 101%, a satisfactory level. Additionally, the optimized mobile phase had a negligible effect on the C18 column stability. Therefore, the developed method was safe, rapid, and valid for anthocyanin analysis.
研究领域:
分析化学
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食品科学
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植物科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2018
·Vol. 99
·期 7
·3343-3349
·
IF 2.379
Hongxia Liu,Huifang Zhao,Lianfei Lyu,Zhengjin Huang,Sufan Fan,Wenlong Wu,Weilin Li
BACKGROUND Blackberry postharvest diseases are caused by fungal pathogens, and treatment of fruits with edible, natural products could reduce the postharvest losses and contribute to food sustainability. Based on the hypothesis that inhibition of fungal pathogens will significantly extend the shelf-life of food products, the effects of natural antifungal agents on fungal pathogens were tested. RESULTS Two pathogenic fungal isolates, Aspergillus japonicus and Gilbertella persicaria , from infected blackberry fruits were identified morphologically using scanning electron microscopy and confirmed by DNA sequence analysis. The inhibitory effects and synergistic action of natural antifungal agents against the two fungal isolates were investigated. The results obtained demonstrated that the natamycin, chitosan and ferulic acid exhibited significant antifungal activities against the tested strains based on the calculated minimum inhibitory concentration. The best antifungal activity was obtained using a combination of ferulic acid and natamycin, which generated a total synergistic effect on both tested strains with a fractional inhibitory concentration index of 0.281. Application of the selected agents on postharvest blackberry fruits reduced the rot ratio and weight loss and also increased fruit firmness. In addition, the shelf-life of fresh blackberry fruits was extended up to 12–15 days at 4 °C and 90 ± 5% relative humidity. CONCLUSION The combined utilization of ferulic acid and natamycin showed synergistic antifungal activity against two pathogenic fungal isolates, and extended the shelf life of fresh blackberry fruits up to 12–15 days. © 2018 Society of Chemical Industry
研究领域:
食品科学
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植物病理学
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药理学
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产品关联
DOI
PubMed
高影响因子
Food & Function
·
2021
·Vol. 12
·期 12
·5451-5464
·
IF 5.396
Zu-Man Dou,Chun Chen,Qiang Huang,Xiong Fu
A novel heteropolysaccharide fraction (BBP-24-3) with a relative molecular weight of 145.1 kDa was isolated from blackberry fruits. The BBP-24-3 was mainly composed of arabinose, glucose, and galacturonic acid with a ratio of 5.30 : 3.60 : 91.10 mol%. Structural analysis showed that BBP-24-3 possessed a 1,6-linked β-D-Glcp, 1, 2, 3, 5 linked α-L-Araf, and 1, 4 linked α-D-GalpA backbone with branches substituted at the C-2 and C-5 positions of arabinose units, which included 1, 2, 3, 4 linked β-D-Glcp and T-linked β-D-GalpA. The conformation analysis indicated that BBP-24-3 exhibited a solid spherical structure with a uniform distribution in 0.1 M NaCl solution. The BBP-24-3 exhibited excellent α-glucosidase inhibitory activity with an IC50 value of 3.70 mg mL−1, which was due to the structural change, including α-helix and random coil of α-glucosidase caused by BBP-24-3. The current work suggests the potential utilization of BBP-24-3 as an α-glucosidase inhibitor in healthy food for reducing the postprandial blood glucose level.
研究领域:
食品科学
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药理学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOELECTROCHEMISTRY
·
2022
·
IF 5.76
Sasan Radfar,Reza Ghanbari,Ali Attaripour Isfahani,Halimeh Rezaei,Majid Kheirollahi
Determination of microRNAs (miRNAs) as valuable blood-borne biomarkers has attracted many scientific attentions. However, analytical methods are still restricted by miRNAs intrinsic characteristics. In this study, for the first time, novel blackberry-like magnetic DNA/FMMA nanospheres were synthesized and mounted on a gold stir-bar as signal amplification probes. To produce this strong electrochemical signal label, double strand DNAs were immobilized on gold coated magnetic nanospheres through a hybridization chain reaction followed by reversible addition-fragmentation chain-transfer polymerization, which brought a great quantity of the electroactive tags (FMMA) on the nanosphere surface. These nanospheres were then fixed on the gold stir-bar as signal probes. The magnetic DNA/FMMA nanosphere probes can be released by substituting with the newly emerging DNA fragments of catalyzed hairpin assembly products. Eventually, these signal probes were magnetically enriched on the electrode surface to produce electrochemical signal and finally, the biosensor was developed to detect miRNA-106a (model target). The suggested aptamer-based biosensor demonstrated considerable selectivity, acceptable storage stability, high specificity, and excellent performance in real sample analysis without any pretreatments. As a result, current study reveals that the developed strategy has a great potential for the early diagnosis of gastric cancer and additionally the clinical monitoring of any miRNA sequences.
研究领域:
生物化学
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纳米技术
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生物医学工程
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癌症研究
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Zhengjie Gong,Tao Ma,Feng Liang
Organic dyes and nitrophenols in the textile industry are wastewater pollutants. In order to develop an efficient nanocatalysts to remove organic pollutants in wastewater, the trimetallic Ni@Cu@Pd nanoparticles (Ni@Cu@Pd NPs) with a blackberry-like structure was successfully prepared by a seed mediated growth method for the first time. The blackberry-like structure and the presence of Ni, Cu and Pd have been confirmed through TEM, SEM, EDS and XPS characterizations. Owing to the charge interaction between metal species along with blackberry-like structure, trimetallic Ni@Cu@Pd NPs delivered a record high catalytic activity toward the reduction of rhodamine B (RhB), with an apparent rate constant of 7.20 min −1 . Ni@Cu@Pd NPs also exhibited high activity for the catalytic reduction of methylene blue (MB) and 4-nitrophenol (4-NP). Moreover, the Ni@Cu@Pd NPs catalyst showed excellent stability and reusability.
研究领域:
环境科学
·
纳米技术
·
催化
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2018
·
IF 4.946
Vemana Gowd,Tao Bao,Liling Wang,Ying Huang,Shenghuizi Chen,Xiaodong Zheng,Sunliang Cui,Wei Chen
Blackberry fruit contains high levels of polyphenols particularly anthocyanins which contribute to its biological activities. Bioavailability of polyphenols especially anthocyanins is generally low, it has been proposed that metabolites from polyphenol biotransformation under colonic fermentation are components that exert health benefits. In this study, blackberry was subjected to simulated gastrointestinal digestion and gut microbiota fermentation at different time intervals (0–48 h) to study the changes in bioactive components, its antioxidant and antidiabetic activities. Phenolic compounds, during digestion and fermentation were also analysed. Gut metabolites of blackberry significantly increased the glucose consumption and glycogen content in HepG2 cells. Furthermore, gut metabolites ameliorated high glucose plus palmitic acid-induced ROS overproduction, mitochondrial membrane collapse, and glutathione depletion in HepG2 cells. The mechanism of antidiabetic activity of blackberry was via its potent antioxidant activity. Therefore, our results suggest that blackberry could be recommended as a functional food due to potential antioxidant and antidiabetic activity.
研究领域:
食品科学
·
营养学
·
微生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）