JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Ruijuan Duan,Meiling Qi
This work presents the investigation of two new pentiptycene (PP)-functionalized triblock copolymers (PEPE1, PEPE2) for gas chromatographic (GC) analyses with an aim to address the separation problems toward analytes of high resemblance in properties and a wide variety of components in complex samples. Up to date, these two materials are not reported in any fields. The PEPE1 and PEPE2 columns showed close column efficiency (above 4000 plates/m) but differed in polarity, morphology and separation performance. As testified by the challenging Grob test mixture, the PEPE1 column exhibited comprehensively higher separation capability than the PEPE2 column and the commercial reference columns. Also, the PEPE1 column achieved high-resolution performance for both apolar and polar isomers of high resemblance, such as xylenes, phenols and anilines. Moreover, it displayed high inertness towards carboxylic acids and excellent separation repeatability and reproducibility tested by the aniline isomers with the RSD values in the range of 0.01–0.04% for run-to-run, 0.09–0.13% for day-to-day and 1.2–2.0% for column-to-column, respectively. Its application to GC–MS analysis of the essential oil from tea flowers demonstrated its advantageous separation performance towards a wide range of components and proved its feasibility for practical analyses of complex samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Tao Sun,Qiuchen Huang,Wei Zhang,Ruonan Chen,Wei Li,Haipeng Chen,Shaoqiang Hu,Zhiqiang Cai
Pillar[ n ]arenes possess highly symmetrical and rigid pillar-shaped architecture with π -electron rich cavity that afford their reliable host-guest recognition interactions towards matched guests. In this work, a novel amphiphilic pillar[5]arene (P5A-C10-2NH 2 ) was designed, synthesized and employed as the stationary phase for capillary gas chromatography. To date, they have not been reported in the field of chromatography. The P5A-C10-2NH 2 capillary column (10 m × 0.25 mm i.d.) was prepared by static coating method. Its capillary column exhibited moderate polarity and column efficiency of 2265 plates/m determined by naphthalene at 120 °C. As evidenced, the P5A-C10-2NH 2 column achieved advantageous separation performance for a mixture of 24 analytes of diverse types and exhibited different chromatographic selectivity from two pillar[5]arene derivatives columns and commercial HP-35 column with 35%-phenyl-methylpolysiloxane. Moreover, the P5A-C10-2NH 2 column baseline resolved more than a dozen positional and cis - trans isomers. Furthermore, the separation mechanism of P5A-C10-2NH 2 column was discussed by quantum chemical calculations. In addition, the P5A-C10-2NH 2 column had high thermal stability and excellent separation repeatability 0.01–0.04% for run-to-run, 0.03–0.17% for day-to-day and 3.2–3.9% for column-to-column. The special amphiphilic structure and high resolution for various analytes reveal the good potential of pillararenes as a new class of stationary phases for chromatographic analyses. Moreover, the TPG column achieved improved thermal stability over the GIL column and excellent repeatability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Xiaomin Shuai,Zhiqiang Cai,Yujie Chen,Xinyu Zhao,Qianqian Song,Kaixin Ren,Xingxing Jiang,Tao Sun,Shaoqiang Hu
Here we report the first example of employing p- nitro-octadecyloxy-calix[8]arene (C8A-NO 2 ) as stationary phase for capillary gas chromatographic (GC) separations. The statically coated C8A-NO 2 column provided column efficiencies of 2554 plates/m and showed moderate polarity. Its selectivity and retention behaviour were investigated by a number of mixtures of diverse analytes and their isomers. It was found that the C8A-NO 2 column exhibited high resolving capability for aliphatic and aromatic analytes from apolar to polar nature, especially for positional and structural isomers. Among them, advantageous resolving capability over the commercial polysiloxane DB-1701 and DB-17 columns was obtained for chloroaniline and bromoaniline isomers. In addition, the C8A-NO 2 column was applied for the determination of isomer impurities in commercial reagents of geraniol, cis -decahydronaphthalene, and trans -decahydronaphthalene.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2019
·
IF 3.858
Tiantian Shi,Meiling Qi,Xuebin Huang
Developing highly selective stationary phases is essential to address the issues for separation of analytes with similar properties and various components in complex samples. Herein, we report a new triptycene-based material functionalized with polycaprolactone moieties (TP-PCL) as the stationary phase with high-resolution performance for gas chromatography (GC). The TP-PCL capillary column exhibited column efficiency of 5555 plates/m and moderate polarity. On the column, dozens of mixtures of positional and structural isomers can be well resolved, involving benzene derivatives with varying substituents (alkyl, halo, nitro, hydroxyl, amino), naphthalene derivatives, alkanes and alcohols. It exhibits advantageous performance for high resolution of the critical pairs of alkylbenzenes, phenols, anilines and alkanes over the PCL column and commercial DB-35 MS column with similar polarity. Moreover, the TP-PCL column showed excellent separation repeatability and reproducibility with RSD values of 0.02%−0.07% for run-to-run ( n = 4), 0.11%−0.18% for day-to-day ( n = 4) and 2.1%−4.7% for column-to-column ( n = 4). In addition, it exhibited distinctly enhanced thermal stability in contrast to the PCL column. Its application to analysis of the essential oil from Artemisiae argyi proves its good potential for practical use.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Wen-Chao Deng,Hai-Long Qian,Cheng Yang,Shu-Ting Xu,Xiu-Ping Yan
Covalent organic frameworks (COFs) are promising as stationary phases for gas chromatography (GC). The successful anchoring of COFs to the inner walls of the capillary with good uniformity is an important prerequisite to ensure the excellent separation performance of columns. However, current methods for the fabrication of COF-based capillary columns cannot always meet this requirement when faced with different COFs, which hampers the further development of COF-based GC stationary phases. Here, we show a general two-step method for the fabrication of COF-bound capillary column. The first step enables the formation of uniform amorphous polymer layer on the inner walls of capillary, while the second step allows the facile transformation of the amorphous polymer layer into a highly crystalline COF layer. COF-bound capillary columns with different framework structures were fabricated successfully by the developed two-step method. Impressively, the COF layers bound on the inner walls of these capillary columns showed good uniformity and high crystallinity. More importantly, as an example, the fabricated Tab-DHTA-bound capillary column showed good resolution (R > 1.5) and high column efficiency (700–39,663 plates m–1) for the tested isomers of ethylbenzene, xylene, dichlorobenzene, chlorotoluene, pinene, 1,3-dichloropropene, and propylbenzene with good precision (RSD, run-to-run, n = 5) (retention time, 0.2–0.6%; peak area, 0.5–1.1%; and peak height, 0.5–1.4%). In general, the fabricated Tab-DHTA-bound capillary column exhibited better performance for the separation isomers than commercial columns DB-5 and HP-FFAP. These results indicate that the two-step method is an efficient way to fabricate the COF-bound capillary column with excellent separation performance.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2018
·
IF 3.716
Jianlin Peng,Meiling Qi
This work describes the investigation of utilizing a chain-typed thiophene-based π-conjugated polymer, i . e ., poly(3-hexylthiophene) (P3HT), as the stationary phase for gas chromatography (GC). The P3HT column was statically prepared and investigated for its column efficiency, polarity, separation performance, repeatability and thermal stability. As a result, it showed moderate polarity and column efficiencies of 3260, 3310 and 3790 plates/m for 1-octanol, naphthalene and n -dodecane, respectively. As evidenced, it exhibited high-resolution performance for aliphatic and aromatic isomers, including those critical pairs such as phenanthrene/anthracene and p -/ m -benzenediol isomers. Moreover, it displayed stronger retention for alkanes, alcohols and phenols in comparison to the polysiloxane stationary phase with close polarity. Also, the P3HT column had good repeatability and reproducibility with the RSD values less than 0.05% for run-to-run, 0.17–0.54% for day-to-day and 2.7–5.2% for column-to-column, and good thermal stability up to 260 °C. This work demonstrates the promising future of the thiophene-based polymer and its derivatives in separation science.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2016
·
IF 3.926
Yunzhong Zheng,Meiling Qi,Ruonong Fu
This work presents the first example of utilization of graphitic carbon nitride (g-C 3 N 4 ) as stationary phase for capillary gas chromatographic (GC) separations. The statically coated g-C 3 N 4 column showed the column efficiencies of 3760 plates/m and weak polarity. Its resolving capability and retention behaviours were investigated by using the Grob test mixture, and mixtures of diverse types of analytes, and structural and positional isomers. The results showed superior separation performance of the g-C 3 N 4 stationary phase for some critical analytes and preferential retention for aromatic analytes. Specifically, it exhibited high-resolution capability for aromatic and aliphatic isomers such as methylnaphthalenes and dimethylnaphthalenes , phenanthrene and anthracene and alkane isomers. In addition, g-C 3 N 4 column showed excellent thermal stability up to 280 °C and good repeatability with relative standard deviation (RSD) values less than 0.09% for intra-day, below 0.23% for inter-day and in the range of 1.9–8.4% for between-column, respectively. The advantageous separation performance shows the potential of g-C 3 N 4 and related materials as stationary phase in GC and other separation technologies.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2016
·
IF 3.926
Jianlin Peng,Yan Zhang,Xiaohong Yang,Meiling Qi
Efficient separation of xylenes, phenols and anilines is a big issue in chemical and petroleum industries. This work presents the first example of employing poly (caprolactone) diol (PCL-Diol) as stationary phase for high-resolution gas chromatographic (GC) separations of these tough isomer mixtures. It showed medium polarity and stronger H-bonding basicity than H-bonding acidity. Impressively, PCL-Diol column exhibited extremely high resolving capability for the isomer mixtures of xylenes, cresols/xylenols, and toluidines/xylidines with good peak shapes. Moreover, it exhibited preferential retention for analytes of a linear alkyl chain, suggesting its shape fitting selectivity for specific analytes. In addition, its separation performance has good repeatability with RSD values on retention times below 0.01% for run to run ( n = 6), 0.67–0.80% for day to day ( n = 4) and 3.2–4.4% for column to column ( n = 4) repeatability, respectively. Furthermore, it was applied for the determination of isomer impurities in real samples, showing good potential for practical use. This work demonstrates the advantageous high-resolution separation performance for challenging isomers and shows its promising future of PCL-Diol-based materials in separation science.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2016
·
IF 3.926
Jianlin Peng,Yonggang Shi,Zhishuai Yang,Meiling Qi,Feng Wang
Dicyanuric-functionalized polycaprolactone (DPCL) was explored for its separation performance in gas chromatography (GC). The statically coated DPCL capillary column (0.25 mm, i.d.) showed column efficiency of 3460 plates/m determined by naphthalene at 120 °C. McReynolds constants and Abrahaḿs system constants were also determined to evaluate the polarity and possible molecular interactions of the stationary phase. As a result, DPCL column exhibited excellent separation performance for diverse types of analytes with good peak shapes. Most interestingly, it shows unique amphiphilic selectivity and high-resolution capability for both apolar to polar isomers. In addition, DPCL column had good column repeatability with the RSD values below 0.06% for run-to-run, 0.09–0.40% for day-to-day and 1.7–3.6% for column-to-column, and good thermal stability up to 280 °C. The high selectivity and resolving capability demonstrate the great advantages of the DPCL stationary phase for simultaneous determination of analytes of great variety in complex samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Qiaochu Zhang,Meiling Qi,Jinliang Wang
This work reports oligothiophene-functionalized truxene-based stationary phases (TTT, TDT and TFT) with a unique star-shaped π-conjugated architecture for gas chromatographic (GC) separations. They exhibited medium polarity and column efficiency of 3340–3760 plates/m determined by naphthalene at 120 °C. Among them, the TTT stationary phase displayed advantageous resolving capability over the TDT and TFT phases for a wide ranging analytes from apolar to polar, particularly for structural and positional isomers, including alcohols, phenols, halogenated and alkylated benzenes and naphthalenes. Moreover, the TTT column exhibited good thermal stability and repeatability with relative standard deviation (RSD) values of 0.02%–0.07% for run-to-run, 0.10%–0.53% for day-to-day and 2.1%–2.9% for column-to-column, respectively. In addition, it was applied for the determination of isomer impurities in real samples, proving its good potential for practical GC analysis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）