EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Yirong Fan,Tao Wang,Hui Sun
Metal ion coordination has critical influence on the self-assembly behavior of amphiphilic polymers and the morphology of the obtained assemblies. Herein, an amphiphilic homopolymer with 2,2′-bipyridine (BPy) as side chain is synthesized (noted as PBPyAA), which can self-assemble into bowl-shaped nanoparticles (BNPs) in tetrahydrofuran (THF)/water. Taking advantage of the coordination interaction between BPy and metal ions, Fe 2+ is chosen to regulate the self-assembly behavior and the morphology of the assemblies of PBPyAA in two pathways. (Ⅰ) The aqueous solution of Fe 2+ with various concentrations is added to the THF solution of PBPyAA during self-assembly. (Ⅱ) Fe 2+ is added into the THF solution of PBPyAA before self-assembly, followed by the addition of deionized water to promote the self-assembly. The results show that the pathway Ⅰ facilitates the coordination of BPy and Fe 2+ . With the increase of the concentration of Fe 2+ aqueous solution, the coordination efficiency of BPy increases from 0.419 % to 7.789 %, leading to the transformation of BNPs to vesicles. Though the coordination efficiency of BPy also increases with the concentration of Fe 2+ in pathway Ⅱ, which is still quite low of 0.274 % to 0.366 %, and the morphology of the BNPs barely changes. In addition, ethylene diamine tetraacetic acid (EDTA), a strong chelating agent, is also added to promote the competitive complexation with BPy, resulting in the dissociation of BPy and Fe 2+ and the reversible transformation from vesicles to BNPs. Overall, the effect of Fe 2+ coordination on the self-assembly behavior of PBPyAA in two pathways is investigated and the reversible transformation of BNPs to vesicles is also achieved.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF INVERTEBRATE PATHOLOGY
·
2018
·
IF 2.511
Tongxiang Song,Huijie Liu,Tengteng Lv,Xuelin Zhao,Yina Shao,Qingxi Han,Chenghua Li,Weiwei Zhang
Under low iron bioavailability environment, many bacteria acquire iron for growth and survival through siderophore-mediated iron acquisition systems. However, until now, little research on the growth, siderophore production and siderophore receptors of Vibrio splendidus Vs under iron limited conditions has been reported. In our present study, V. splendidus Vs could survive in media supplemented with 160 µM 2,2′-dipyridyl (DIP), but 74.5% of the growth was suppressed at 48 h, while the siderophore production of V. splendidus Vs increased by 35.9%. As the OD 600 of V. splendidus Vs decreased when the concentration of DIP was increased from 40 to 80 µM, the siderophore production of V. splendidus Vs increased from 34.0% to 43.4% at 24 h, and it was further determined to be a hydroxamate siderophore. To explore the potential siderophore receptors anchored on the outer membrane of V. splendidus Vs, outer membrane proteins from cells grown with and without 80 µM DIP were extracted and the differentially expressed proteins were identified by SDS-PAGE and MALDI-TOF/TOF MS. Five proteins, aerobactin siderophore receptor IutA, enterobactin receptor protein FepA, ATP synthase subunit A, ATP synthase subunit B and the ATP synthase F0F1 subunit beta were identified. Real-time reverse transcriptase PCR showed that mRNA levels of iutA , fepA, atpA , atpB and atpβ - F0F1 were upregulated 271.5-, 15.1-, 1.1-, 2.5- and 67.9-fold respectively, after 6 h in cells treated with 80 µM DIP. In addition, the promoters of the siderophore receptor genes of iutA and fepA had apparent ferric uptake regulator (Fur) binding sites. Combined with the simultaneous production of both the hydroxamate siderophore and its corresponding aerobactin siderophore receptor IutA, these results suggested that there might be a hydroxamate siderophore-IutA mediated iron uptake pathway in V. splendidus Vs.
研究领域:
微生物学
·
海洋生物学
·
分子生物学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yujie Chen,Rui Sun,Wenhui Zhu,Zhen Zhang,Yali Chen,Shuo Wang,Qiliang Deng
Covalent organic frameworks (COFs) with predesigned bipyridine recognition sites (donated as BPD-COFs) were prepared by using 2, 2’-bipyridine-5, 5’-diamine and benzene-1, 3, 5-tricarbaldehyde as monomers, and the corresponding small molecule model compound (2, 2’-bipyridine-5, 5’-diiminebenzene, donated as BPDB) was synthesized by using benzaldehyde and 2, 2’-bipyridine-5, 5’-diamine. The fluorescence sensing property between BPD-COFs and BPDB were compared as the fluorescence sensing platform for the sensitive, selective and rapid detection of Ni 2+ . The unique structure characteristics such as large conjugated structure, high surface area, regularity pore canals and predesigned bipyridine link endow BPD-COFs with prominent fluorescence emission, enough space and strong specificity for Ni 2+ . The fluorescence quenching degree of BPD-COFs is four times more than that of BPDB. Besides better selectivity, BPD-COFs also displays the prominent advantages, such as the wider concentration range (4.20 × 10 −10 ∼1.26 × 10 -6 M) and lower limit of detection (6.80 × 10 -11 M) compared to that of BPDB (1.00 × 10 -7 ∼5.00 × 10 -7 M, 4.50 × 10 -8 M). Good spiked recoveries (>92.0 %) in chocolate and tea support that BPD-COFs is competent to detect Ni 2+ in real samples. All these results indicate that BPD-COFs is potential as a fast, sensitive, and accurate fluorescence sensing platform for the selective detection of Ni 2+ in complex system.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Ya-Nan Zhang,Shuai Feng,Shi-Hua Zhao,Bo-Wen Gao,Cheng-Xiang Wang
Perovskite solar cells (PSCs) have emerged as a leading photovoltaic technology due to their high efficiency and low cost. Even though they have developed rapidly since their inception, with efficiencies of over 26%, inverted PSCs face challenges such as nonradiative recombination and ion migration. Surface treatment, especially the utilization of organic compounds, has improved efficiency and stability by optimizing the perovskite–charge transport layer interface. Herein, we report a facile and effective strategy by introducing 2,2′-bipyridyl to modify the surface of perovskite, achieving a power conversion efficiency of 24.43% with increasing open-circuit voltage and fill factor and good repeatability on multiple devices. We reveal that the 2,2′-bipyridyl molecule can chelate lead ions on the surface of perovskite, effectively suppressing nonradiative recombination. Furthermore, this modification can induce surficial n-doping to refine the energy level alignment, thereby minimizing charge transport losses. Additionally, the device maintained over 92% of the initial efficiency after 1000 h of operation at the maximum power point under continuous illumination. This surface chelation and defect passivation strategy employing 2,2′-bipyridyl offers a promising avenue for exploring the details of potential long-term degradation mechanisms and the development of commercially viable high-performance p-i-n PSCs.
研究领域:
材料科学
·
光伏技术
·
化学工程
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Ala’a Mhmoued Abdllh Alboull,Hao Jiang,Tasneem Omda Edrees Isaa,Zhiyong Dong,Tadele Eticha,Guobao Xu
Sugar alcohols are low-calorie sugar substitutes commonly used in sugar-free products. In this study, we report for the first time Ru(bpy)32+ electrochemiluminescence (ECL) of sugar alcohols. Ru(bpy)32+ ECL of sugar alcohols, including sorbitol, mannitol, isbitol (also called isomalt, isomaltitol, and palatinitol), maltitol, lactitol, xylitol, and erythritol, was investigated. The applicability of the Ru(bpy)32+ ECL system for sugar alcohol detection was demonstrated by using sorbitol as a representative analyte. The optimized system exhibited excellent analytical performance, with a wide linear detection range from 0.5 μM to 5 mM and a low detection limit of 0.026 μM (S/N = 3). In practical applications, the system demonstrated outstanding accuracy in detecting sorbitol in pharmaceutical samples, with recovery rates ranging from 97.75 to 104.00%. These findings establish the Ru(bpy)32+ ECL as an effective and sensitive method for the detection of sugar alcohols.
研究领域:
分析化学
·
电化学
·
食品科学
·
药物分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS RESEARCH INNOVATIONS
·
2020
·
IF 0
Wenyan Huang,Haiyan Wu,Yi Fan,Xiaoqiang Xue,Hongjun Yang,Li Jiang,Qimin Jiang,Bibiao Jiang
Self-designed bis(4-vinylbenzyl)-oxalate (DBE) was synthesized successfully. The branched polystyrene was prepared by using an atom transfer radical polymerization method with copper bromide (CuBr)/2,2'-bipyridine (Bpy) as a catalyst, the DBE as a branched monomer and tert-butyl α-bromoisobutyrate (t-BBiB) as an initiator. The structure of the synthesized branched monomer was determined by nuclear magnetic resonance (NMR) spectroscopy. The conversion of monomer during the polymerization was measured by gas chromatography (GC) while the molecular weight, molecular weight distribution and degree of branching of the polystyrene were characterized by three-detection volume exclusion chromatography (TD-SEC). The results show that bis(4-vinylbenzyl)-oxalate with electron-rich double bond and styrene with electron-rich double bond can be successfully obtained branched polystyrene. The branched structure developed as the reaction proceeded. At the same time, the molecular weight of the branched polystyrene gradually increased as the reaction progressed, and the molecular weight distribution widened consistent with the increased degree of branching.
研究领域:
高分子化学
·
材料科学
✓ 已验证
DOI
ANALYTICAL CHEMISTRY
·
2021
·
IF 6.986
Xinyang Zhu,Huanhuan Xing,Yuan Xue,Jing Li,Erkang Wang,Shaojun Dong
A chemical fixation strategy originating from single-atom-anchoring with metal–organic frameworks as a carrying matrix was proposed for solid-state electrochemiluminescence (ECL). Herein, UiO-67(N) with the exposure of 2,2′-bipyridine (bpy) ligands could coordinate with Ru2+ to form a local structure of [Ru(bpy)3]2+ (Ru-UiO). The influence of the steric effect induced with different Ru sources was discussed. The as-obtained Ru-UiO exhibits high ECL intensity and outstanding stability in the presence of a coreactant at low concentrations. The proposed synthesis strategy may hold great potential for the synthesis of solid-state ECL materials and their further utilization in ECL analysis.
研究领域:
材料科学
·
分析化学
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2019
·
IF 6.35
Muhammad Saqib,Shahida Bashir,Haijuan Li,Chuanping Li,Shanshan Wang,Yongdong Jin
Developing rapid, specific, and low-cost electrogenerated chemiluminescence (ECL) systems remains a compelling goal for many applications including environmental analysis, clinical diagnostics, and food safety. In this study, N-hydroxysuccinimide (NHS) esters, especially N-hydroxysulfosuccinimide (NHSS), was exploited for the first time as an efficient coreactant for anodic Ru(bpy)32+ ECL in neutral medium. Among the three tested NHS esters (NHS, NHSS, NHPI), the NHSS exhibited much higher ECL intensity and stability than the sulfonate-free esters, suggesting the essential role of both the N-hydroxy (NOH) and sulfonate (SO3H) moieties in the developed Ru(bpy)32+ ECL system. The ECL generation process is rather straightforward, not requiring time-consuming fabrication/modification steps of electrodes. The anodic Ru(bpy)32+–NHSS system achieved ECL detections with high selectivity and sensitivity toward l-proline (LOD = 50 nM) and Hg2+ (LOD = 10 nM), with a linear range of 0.5–200 μM and 0.1–25 μM, respectively. The method showed good recoveries (95.2–104.8%) for l-proline and Hg2+ detection in real samples. This study is a successful step toward the development of new coreactants and may open new avenues for the applications of N-hydroxy compounds in ECL sensing.
研究领域:
分析化学
·
环境科学
·
临床诊断
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食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2012
·Vol. 5
·期 4
·982-986
·
IF 1.547
Mao Deng,Fu-nan Chen,Xing-yu Long
In the present work, a new method of chemiluminescence detection coupled with high performance liquid chromatography for three organic acids—tartaric, malic and citric acids is described. The detection is based on the enhancement of the organic acids for the chemiluminescence reaction between cerous sulfate (Ce(SO4)2) and tris (2,2′-bipyridyl)ruthenium(II) (Ru(bipy)32+). The latter was immobilized on the cationic ion-exchange resin for obtaining high sensitivity and reducing consumption of expensive reagent. Under the optimal conditions, the linear ranges were 7.5 × 10−7 g mL−1 to 7 × 10−6 g mL−1 for tartaric acid, 4.0 × 10−7 g mL−1 to 1.0 × 10−5 g mL−1 for malic acid and 1 × 10−7 g mL−1 to 1.5 × 10−6 g mL−1 for citric acid, and the detection limits were 1.5 × 10−7 g mL−1, 2.0 × 10−7 g mL−1, 4.0 × 10−8 g mL−1 for tartaric, malic and citric acid, respectively. The proposed method had been successfully applied to the determination of three organic acids in fruit juice – with only filtration and dilution steps.
研究领域:
分析化学
·
食品科学
·
色谱学
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 9
·1-11
·
IF 6.408
Zhai Hongguo,Wang Yue,Yin Jiaqi,Zhang Yuhao,Guo Qi,Sun Xia,Guo Yemin,Yang Qingqing,Li Falan,Zhang Yanyan
MXene@Au as the base and Au@SiO 2 as signal amplification factor were used for constructing an ultrasensitive “on–off” electrochemiluminescence (ECL) biosensor for the detection of Pb 2+ in water. The use of MXene@Au composite provided a good interface environment for the loading of tris(2,2-bipyridyl)ruthenium(II) (Ru(bpy) 3 2+ ) on the electrode. Based on resonance energy transfer, the Au (core) SiO 2 (shell) (Au@SiO 2 ) nanoparticles stimulate electron transport and promote tripropylamine (TPrA) oxidation. The luminescence effect of Au@SiO 2 was five times that of AuNPs and SiO 2 nanomaterials alone, and the ECL intensity was greatly improved. In addition, Pb 2+ activated the aptamer to exert its endonuclease activity, which realized the signal cycle amplification in the process of Pb 2+ detection. When Pb 2+ was added, the ECL signal weakened, and the Pb 2+ concentration was detected according to the decreased ECL intensity. Under optimized experimental conditions, this aptamer sensor for Pb 2+ has a wide detection range (0.1 to 1 × 10 6 ng L −1 ) and a low detection limit (0.059 ng L −1 ). The relative standard deviation (RSD) of the sensor is 0.39–0.99%, and the recovery of spiked standard is between 90.00 and 125.70%. The sensor shows good selectivity and high sensitivity in actual water sample analysis. This signal amplification strategy possibly provides a new method for the detection of other heavy metal ions and small molecules. Graphical abstract
研究领域:
分析化学
·
环境科学
·
材料科学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yusheng Wu,Dongmiao Qin,Juan Yang,Shenglan Hu,Lixin Xu,Biyang Deng
Drug imaging detection is of great significance for pharmacokinetic studies and for guiding clinical treatment. Electrochemiluminescence microscopy (ECLM) is an emerging technology for drug imaging. This study reports the embedding of tris(2,2′-bipyridyl)ruthenium (Ru-bpy) in a zinc-based metal–organic framework (Zn-MOF). Due to the excellent emission and repeatability of Zn-MOF@Ru, we used it for visual drug detection. To demonstrate this concept, we established a new drug imaging detection method using a smartphone-based ECLM (SECLM) to capture images. We used a molecularly-imprinted polymer to ensure the selectivity of the method using captopril (CTP) as a model compound. The concentration of CTP showed a linear relationship to the quenching efficiency within the range of 1–1 × 10 5 μmol/L, with a detection limit of 0.29 μmol/L. This method is expected to be widely used for pharmacokinetic research, drug molecular dynamics, drug mechanism research, and drug toxicology research. It provides a new strategy for promoting pharmacological research and drug screening.
研究领域:
分析化学
·
药学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE
·
2019
·Vol. 645
·期 23
·1341-1348
·
IF 1.337
Xiong He,Fang Chen,Dan Zhang,Yan Li,Hong-Li Yang,Xiu-Qing Zhang
Based on an asymmetric 1,2,4-benzenetricarboxylic acid (H 3 btc) and 2,2′-bipyridine (bpy), a new Cu II complex, Cu 2 (H 2 btc) 4 (bpy) 2 · 8H 2 O ( 1 ), was synthesized and structurally characterized by single-crystal X-ray diffraction, hirshfeld surface (HS) analysis, IR spectroscopy, powder X-ray analysis, thermal gravimetry analysis (TGA), magnetic susceptibility, EPR measurement, and UV/Vis spectrometry. Complex 1 shows a dinuclear copper structure. The Cu II of each dinuclear moiety are in a slightly distorted square-pyramidal environments. Magnetic susceptibility of 1 shows a ferromagnetic coupling between both metal atoms. The interaction of 1 with bovine serum albumin (BSA) is investigated using UV/Vis, fluorescence spectroscopic methods. The Cu II complex shows strong binding propensity in albumin binding study.
研究领域:
无机化学
·
材料科学
·
生物物理化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）