SCIENCE OF THE TOTAL ENVIRONMENT
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2022
·
IF 10.753
Xiaoxuan Zhou,Tao Liu,Shengyi Zhang,Bo Kang,Xu Duan,Yuanyuan Yan,Leiyu Feng,Yinguang Chen
Fluorene (Flu) occurs widely in various environments and its toxicity to organisms is well-known. However, the impact of Flu on complicated biochemical processes involving functional microbial community has been reported rarely. In this study, the facilitation of Flu on the volatile fatty acids (VFAs) generation executed by acidogenic microbial population during sludge acidogenic fermentation (37 °C, SRT = 8 d, pH = 10.0) was investigated. The accumulation of VFAs (particularly acetic acid) increased initially and then declined with the increasing of Flu concentration (0‐500 mg/kg dry sludge), which reached a maximum (3211.1 mg COD/L) as Flu content was 200 mg/kg dry sludge . The Flu-enhanced VFAs production was primarily attributed to the shift of hydrolysis/acidification, as well as the corresponding functional microbial community and the activity of enzymes. Based on the metagenomics analysis, the conversion of organic substrates, i.e. amino acid and monosaccharide , into VFAs embraced in hydrolysis/acidification shaped by Flu was constructed at the genetic level. The relative abundances of genes included in aminotransfer and deamination process of amino acid and glycolysis of monosaccharide into VFA-precursors (pyruvate, acetyl-CoA and propionyl-CoA), and the further formation of VFAs were improved due to the Flu presence. This study shed light on the Flu-affected microbial processes at the molecular biology level during acidogenic fermentation and was of great significance in resource recovery of sludge containing persistent organic pollutants.
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CHEMOSPHERE
·
2023
·
IF 8.8
Zhe Zhao,Shumin Lin,Zhendong Yu,Ming Su,Bolong Liang,Shu-Xuan Liang,Xue-Hai Ju
Flumequine (FLU) and nadifloxacin (NAD), as emerging contaminants , have received extensive attention recently. In this study, a triazine-based microporous organic network (TMON) was synthetized and developed as an excellent adsorbent for FLU and NAD. The adsorption behavior and influence factors were investigated in both single and binary systems. Insight into the adsorption mechanisms were conducted through experiments, models, and computational studies, from macro and micro perspectives including functional groups, adsorption sites, adsorption energy and frontier molecular orbital. The results showed that the maximum adsorption capacities of TMON for FLU and NAD are 325.27 and 302.28 mg/g under 30 °C higher than records reported before. TMON exhibits the better adaptability and anti-interference ability for influence factors, leading to the preferable application effect in kinds of real water samples. TMON also shows the application potentials for the adsorption of other quinolone antibiotics and CO 2 capture. Hydrogen-bonding interaction played the most critical role compared to π-π stacking effect, π-π electron-donor-acceptor interaction, CH-π interaction, and hydrophobic interaction during the adsorption. TMON could be regarded as a promising environmental adsorbent for its large surface area, stable physical and chemical properties, excellent recyclability , and wide range of applications.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2022
·
IF 10.753
Yue Cai,Binbin Yuan,Xiaoyue Ma,Guodong Fang,Dongmei Zhou,Juan Gao
Nano-enabled foliar-application could be an ideal strategy for advancing agricultural productivity. However, it remains largely unknown whether they inhibit or promote the uptake of pollutants. Here, we systematically examined how foliar applying SiO 2 nanoparticles (nSiO 2 ) and ZnO nanoparticles (nZnO) (20 nm, 100 mg·L −1 ), influence polycyclic aromatic hydrocarbons (PAHs) uptake in 4-week-old amaranth ( Amaranthus tricolor L.). Results showed that foliar application of nSiO 2 or nZnO enhanced amaranth biomass by 20.2–26.4% but decreased PAHs bioaccumulation in leaves by 20.4–54.9% after 7-d incubation. Changes regarding amino acid-related pathways (alanine/aspartate/glutamate metabolism and arginine biosynthesis) and energy maintenance pathways (TCA cycle) were observed in amaranth leaves after foliar application of nSiO 2 and nZnO. Specific PLS-DA analyses with total PAHs uptake as the biological endpoint showed that the contents of PAHs positively correlated with valine ( R 2 = 0.799) and tyrosine ( R 2 = 0.789), but negatively correlated with D-tagatose ( R 2 = 0.805) and L-gulonolactone ( R 2 = 0.877), indicating greater oxidant stress under higher PAHs level. We propose that mechanisms of declined uptake of PAHs involve the biomass-dependent dilute effect and activation of biological response against PAHs accumulation. These findings provide a prospective vision on how nano-enabled foliar-application alleviates PAH-enriched environmental burden while producing higher-yield agricultural products, especially for low toxic and biocompatible nSiO 2 .
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Yingnan Liu,Wanqi Jiang,Zan Yang,Fei Tong,Lei Wang,Lu Zhu,Zhenyu Yu,Mingming Zheng,Yaqing Xiao,Yibin Zhou
A zein-based film functionalized with fluorescent dyes was constructed for visual, real-time monitoring of seafood freshness. The addition of fluorescent dyes had no significant effect on the mechanical property or water sensitivity of the zein-based film, and the fluorescent film exhibited dual emission response. When exposed to ammonia, fluorescein fluorescence increased whilst the fluorescence of rhodamine B was undisturbed. The fluorescent film presented a clearly distinguishable color transition from pink to green. Sample detection tests showed the fluorescent film served successfully as a response label for on-site visual detection of seafood freshness. Development of this intelligent fluorescent film provides a new platform for food safety and quality monitoring, benefiting economic value and public health.
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ENVIRONMENTAL POLLUTION
·
2021
·
IF 8.071
Xiao-Yong Liao,Xue-Gang Gong,Li-Li Zhang,Daniel P. Cassidy
Interactive effects of inorganic arsenic (As) species and polycyclic aromatic hydrocarbons (PAHs) on their uptake, accumulation and translocation in the hyperaccumulator Pteris vittata L. ( P. vittata ) were studied hydroponically. The presence of PAHs hindered As uptake and acropetal translocation by P. vittata , decreasing As concentrations by 29.8%–54.5% in pinnae, regardless of the initial As speciation. The inhibitive effect of PAHs was 1.6–8.7 times greater for arsenite [As(III)] than for arsenate [As(V)]. Similarly, inorganic As inhibited the uptake of fluorene (FLU) and benzo[a]pyrene (BaP) by P. vittata roots by 0.4%–21.7% and by 33.1%–69.7%, respectively. Interestingly, coexposure to As and PAHs slightly enhanced the translocation of PAHs by P. vittata with their concentrations increased 0.3 to 0.8 times in shoots, except for the As(III)+BaP treatment. The antagonistic interaction between As and PAHs uptake is likely caused by competitive inhibition or oxidative stress injury. By using synchrotron radiation micro X-ray fluorescence imaging, high concentrations of As were found distributed throughout the microstructures far from main vein of the pinnae when coexposed with PAHs, the opposite of what was observed with exposure to As only. PAHs could also significantly inhibit the accumulation and distribution of As in vascular bundles in rachis treated with As(III). The results of two-photon laser scanning confocal microscopy revealed that PAHs were mainly distributed in the vascular cylinder, epidermal cells, vascular bundles, epidermis and vein tissues, and this was independent of As speciation and treatment. This work offers new positive evidence for the interaction between As and PAHs in P. vittata , presents new information on the underlying mechanisms for interactions of As and PAHs affecting their uptake and translocation within P. vittata L., and provides direction for future research on the mechanisms of PAHs uptake by plants.
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PLASMA CHEMISTRY AND PLASMA PROCESSING
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2020
·Vol. 40
·期 6
·1539-1553
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IF 2.178
Yuan Hao,Yang Dezheng,Jia Zixian,Zhou Xiongfeng,Wang Hongli,Xu Qingnan,Wang Wenchun,Xu Yong
In this paper, a nanosecond pulsed discharge was employed to modify activated carbon (AC) adsorbents for the purpose of detecting gas-phase polycyclic aromatic hydrocarbons (PAHs). The raw and modified AC were characterized by helium ion microscopy, N 2 adsorption/desorption, and X-ray photoelectron spectroscopy. The treatment time, gas composition, and pulse peak voltage of discharge were optimized to improve the adsorption capacity of AC. And the adsorption kinetics of AC was investigated. It is found that the pore structure of AC is changed and the oxygen-containing groups on AC surface are increased after plasma treatment. As a result, the roles of physisorption and chemisorption are promoted, and the adsorption rate of naphthalene is improved by about 10%. More importantly, modified AC adsorbing PAHs obeys Pseudo-first-order model and Langmuir isotherm model, and the corresponding adsorption coefficients are fitted, which contributes to detecting PAHs more accurately. After modified AC enriching, the gas-phase PAHs can be detected with the limit of detections in the range of 20–120 μg/m 3 .
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INTERNATIONAL IMMUNOPHARMACOLOGY
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2020
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IF 3.943
He-Tao Bian,Gao-Hua Wang,Jun-Jie Huang,Liang Liang,Ling Xiao,Hui-Ling Wang
Depression is a complex and heterogeneous mental disorder. Yet, the mechanisms behind depression remain elusive. Increasing evidence suggests that inflammatory reaction and microglia activation are involved in the pathogenesis of depression. Scutellarin has been found to have anti-inflammatory and antioxidant effects in various diseases. The aim of the present study was to investigate the anti-depressant effects and potential mechanism of scutellarin in the lipopolysaccharide (LPS)-induced depression animal model. The behavioral tests showed that scutellarin administration ameliorated LPS-induced depressive-like behaviors. Additionally, the scutellarin treatment inhibited reactive oxygen species (ROS) generation. Western blot analysis results showed that scutellarin pretreatment suppressed LPS-induced the protein levels of NLRP3 , caspase-1, and IL-1β. Furthermore, immunostaining results showed that scutellarin pretreatment inhibited LPS-induced microglia activation in the hippocampus of rats. These findings suggest that scutellarin effectively improves LPS-induced inflammation-related depressive-like behaviors by inhibiting LPS-induced neuroinflammation and microglia activation, possibly via regulation of the ROS/NLRP3 signaling pathway and microglia activation. Thus, scutellarin may serve as a potential therapeutic strategy for depression.
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Journal of Neuroinflammation
·
2020
·Vol. 17
·期 1
·1-13
·
IF 5.793
Bian Hetao,Wang Gaohua,Huang Junjie,Liang Liang,Zheng Yage,Wei Yanyan,Wang Hui,Xiao Ling,Wang Huiling
Background Recently, depression has been identified as a prevalent and severe mental disorder. However, the mechanisms underlying the depression risk remain elusive. The neuroinflammation and NLRP3 inflammasome activation are known to be involved in the pathology of depression. Dihydrolipoic acid (DHLA) has been reported as a strong antioxidant and exhibits anti-inflammatory properties in various diseases, albeit the direct relevance between DHLA and depression is yet unknown. The present study aimed to investigate the preventive effect and potential mechanism of DHLA in the lipopolysaccharide (LPS)-induced sickness behavior in rats. Methods Adult male Sprague–Dawley rats were utilized. LPS and DHLA were injected intraperitoneally every 2 days and daily, respectively. Fluoxetine (Flu) was injected intraperitoneally daily. PD98059, an inhibitor of ERK, was injected intraperitoneally 1 h before DHLA injection daily. Small interfering ribonucleic acid (siRNA) for nuclear factor erythroid 2-like (Nrf2) was injected into the bilateral hippocampus 14 days before the DHLA injection. Depression-like behavior tests were performed. Western blot and immunofluorescence staining detected the ERK/Nrf2/HO-1/ROS/NLRP3 pathway-related proteins. Results The DHLA and fluoxetine treatment exerted preventive effects in LPS-induced sickness behavior rats. The DHLA treatment increased the expression of ERK, Nrf2, and HO-1 but decreased the ROS generation levels and reduced the expression of NLRP3, caspase-1, and IL-1β in LPS-induced sickness behavior rats. PD98059 abolished the effects of DHLA on preventive effect as well as the levels of Nrf2 and HO-1 proteins. Similarly, Nrf2 siRNA reversed the preventive effect of DHLA administration via the decreased expression of HO-1. Conclusions These findings suggested that DHLA exerted a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Thus, DHLA may serve as a potential therapeutic strategy for depression.
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BRAIN RESEARCH BULLETIN
·
2020
·
IF 3.37
Zuotian Wu,Gaohua Wang,Huiling Wang,Ling Xiao,Yanyan Wei,Can Yang
Background Recent studies indicate that antidepressants treatment restores neuronal plasticity. In contrast, some researchers claim that serotonergic antidepressants, including fluoxetine (FLU), may exacerbate neuronal plasticity, which is contradictory and rarely studied. Since almost those studies exposed cells with drugs for 1–2 days as treatment models of antidepressants, it is possible that FLU exposure for longer periods would have opposite effects on neuronal plasticity. Results In the present study, we examined the effects of FLU exposure (up to 3 days) on the neuronal plasticity in differentiated PC12 cells. The cell viability shown a slight decrease at day 2 (93.5 ± 3.5 %), followed by a highly significant decrease at day 3(71.4 ± 4.4 %). As previously reported, neuronal plasticity was significantly upregulated by FLU exposure at day 1. However, the neurite length, activity-regulated cytoskeleton-associated protein (Arc) and c-Fos mRNA were inhibited with FLU exposure at day 3. Similarly, the expression of tubulin, which play important roles in the neuronal plasticity, was the same result. Furthermore, we found α-tubulin interacted with collapsing response mediator protein 2(CRMP2), which is related to neuronal plasticity, and the regulation of CRMP2 activity influenced the neurite length, Arc, c-Fos and tubulin expression. Conclusions The results demonstrated that neuronal plasticity was increased by FLU exposure at day 1, but exposure with FLU for more than 2 days had opposite effect on it. The reduction in neuronal plasticity with FLU exposure for more than 2 days might be involved in some aspects of the therapeutic effect of antidepressant on depression.
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JOURNAL OF MOLECULAR LIQUIDS
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2020
·
IF 5.065
Wei Zhang,Peipei Zhou,Wei Liu,Huili Wang,Xuedong Wang
Owing to matrix complexity, the development of green and convenient pretreatment methods is crucial for routine monitoring of organic contaminants in meat samples. Dicationic ionic liquids (DILs) possess two active centers, thus resulting in superior physicochemical properties over monocationic species. Herein, the hydrophilic DILs and in-situ metathesis reaction salt were introduced into NiFe 2 O 4 -based magnetic effervescent tablets for enhancing adsorption/extraction of five typical polycyclic aromatic hydrocarbons (PAHs) in meats. Also, the synthesized NiFe 2 O 4 nanoparticles displayed larger specific surface area than others (CoFe 2 O 4 , Fe 3 O 4 and ZnFe 2 O 4 ), thereby supplying higher adsorption capacity for PAHs. The integration of DILs with NiFe 2 O 4 into magnetic effervescent tablets realized highly efficient adsorption/extraction, rapid magnetic separation/retrieval and CO 2 -induced vigorous dispersion into one synchronous step. After hydrolysis of the ground meat samples using 10 μM KOH, the filtered solution was diluted and subjected to magnetic effervescent tablet-assisted microextraction procedures. Optimized experimental variables were as follows: an effervescent tablet containing 0.7 g Na 2 CO 3 and NaH 2 PO 4 with molar ratio of 1:2; 60 mg [C 4 (MIM) 2 ]Br 2 ; 20 mg NiFe 2 O 4 ; 45 mg Na[N(CN) 2 ] and 500 μL toluene as elution solvent. The effervescent reaction-enhanced microextraction was combined with high performance liquid chromatography and fluorescence detection, rendering limits of detection as low as 0.01–0.07 μg kg −1 with high recoveries (82.3–104.7%) for five PAHs in raw, boiled, charcoal-grilled and smoked meats. To the best of our knowledge, this is the first report on the additive action between DILs and NiFe 2 O 4 in an effervescent reaction-enhanced microextraction, showing great analytical potential in meat matrices.
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MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Jiayang Zhang,Xiwen Ma,Xueping Dang,Huaixia Chen,Yuling Hu
A covalent complex of 3,4-ethylenedioxythiophene (EDOT) and graphene oxide (GO) was electrodeposited on an etched stainless-steel wire to obtain a robust polymeric film. The film presents a more fluffy porous morphology and higher thermal stability, which can be acted as solid phase microextraction (SPME) coating. The adsorption isotherms of the polycyclic aromatic hydrocarbons (PAHs) on the covalent PEDOT-GO coating showed the π stacking interaction happened between them. The coating showed high extraction efficiency for four PAHs, including naphthalene, 1-methyl naphthalene, acenaphthene and fluorene, which was nearly three times that of the PEDOT coating and higher than the commercial coatings. The covalent PEDOT-GO coating was applied to headspace SPME coupled with gas chromatography for the determination of PAHs. The linear range was 0.015–15 μg/L ( R 2 >0.99) and the limit of detection was 0.005–0.01 μg/L (S/N=3). It was successfully applied for the migration determination of PAHs in three types of food contact materials and the recovery was satisfactory in the range of 70–103%.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2019
·
IF 14.229
He Guo,Nan Jiang,Huijuan Wang,Kefeng Shang,Na Lu,Jie Li,Yan Wu
A hybrid graphene-TiO 2 nanocomposites have been prepared by a facile hydrothermal method to improve the photocatalytic performance and applied for synergetic degradation of fluoroquinolone antibiotic in pulsed discharge plasma (PDP) system. The characterizations of the structure and morphology, chemical bonding state, optical property and electrochemical property show that the graphene-TiO 2 nanocomposites can be hybridized successfully. Compared to the pure TiO 2 , the light absorption range can extend to visible light (<505 nm) and the recombination rate of electron–hole pairs declines apparently in the graphene-TiO 2 samples. The degradation performance experiment manifests a significant enhancement of the removal efficiency of flumequine (FLU) when the graphene-TiO 2 samples are added in the PDP system. The highest removal efficiency can reach 99.4% in PDP/graphene-TiO 2 system with 5% graphene content, which is 23.7% and 34.6% higher than that in PDP/TiO 2 system and sole PDP system, respectively. Correspondingly, the kinetic constant is 3.5 and 4.6 times higher than that in PDP/TiO 2 system and sole PDP system, respectively. The radical species trapping test suggests that OH, h + and O 2 − play the critical role for FLU degradation in PDP/graphene-TiO 2 system. The graphene-TiO 2 samples can further decompose the O 3 and improve the generation of OH and H 2 O 2 . The degradation intermediates are determined by LC–MS and IC. The toxicity evolution of FLU reaction solutions is evaluated based on inhibition of photobacterium V. fischeri . Finally, the FLU degradation mechanism in the PDP/graphene-TiO 2 system is proposed. This research would provide a novel insight into the application of graphene-based nanocomposites in PDP system as a promising remediation methodology for organic contaminants in water.
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