PHYCOLOGIA
·
2015
·
IF 1.915
Rui Liu,Xiaofei Ran,Fang Bai,Jinzhu Xu,Songqi Yang,Junqiong Shi,Zhongxing Wu
In order to investigate the toxicity targets of the secondary metabolite from aquatic plants, N-phenyl-2-naphthylamine, on Cylindrospermopsis raciborskii photosynthetic system II (PSII), we determined chlorophyll a (Chl a), specific growth rate (μ−d), photosynthetic rapid light curves and polyphasic Chl a fluorescence transients following exposure to N-phenyl-2-naphthylamine. The results showed significant decreases in Chl a following 48 h at high concentration (0.50 mg l−1) exposure to N-phenyl-2-naphthylamine. The PSII electron transfer rate and Chl a fluorescence transients appeared to be affected after the cells were exposed to concentrations of 0.50, 1.00 and 2.00 mg l−1. Exposure to higher concentration of N-phenyl-2-naphthylamine (> 0.50 mg l−1) mainly depressed the density of reaction centers (RC/CS0) and quantum energy flux ratios (ϕP0 and ϕE0) but increased the absorption flux per RC (ABS/RC), dissipated energy flux per RC (DI0/RC) and the average redox state of QA−/QA in the time span from 0 to tFmax (Sm/tFmax). However, exposure to low concentration (≤ 0.5 mg l−1) mainly inhibited the trapping energy fluxes per reaction center (TR0/RC), electron transport energy fluxes per reaction center (ET0/RC) and energy flux ratio (ψ0). This suggested that the donor and the acceptor sides of PSII were targets of N-phenyl-2-naphthylamine in C. raciborskii. Additionally, our results indicated that the toxicity target at low concentrations of N-phenyl-2-naphthylamine was at each step of electron transport between QA− and the Cyt b6/f complex; whereas, the reduction of QA was the potential target at high concentrations. We suggest that N-phenyl-2-naphthylamine may be a potential allelochemical to control harmful cyanobacterial blooms.
研究领域:
水生生物学
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环境科学
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植物生理学
✓ 已验证
产品关联
DOI
高影响因子
REPRODUCTIVE TOXICOLOGY
·
2025
·
IF 2.8
Zhiheng Shangguan,Kaiqiang Yang,Qi Pan,Hongli Hu,Pan Wang
Endocrine disruptors are environmental chemicals that can interfere with the endocrine system. However, research on endocrine disruptors that interfere with androgen action is still limited. In this study, two new environmental androgens were identified. N-Phenyl-2-naphthylamine (PNA) and o-tolidine are dye intermediates widely used in industry to produce organic pigments. We found that both PNA and o-tolidine activated androgen receptor (AR) transcriptional activity in the luciferase reporter assay and bound to AR-ligand binding domain directly in the surface plasmon resonance analysis. In vivo studies showed that PNA and o-tolidine induced the proliferation of seminal vesicle cells and increased seminal vesicle weight in immature male rats, indicating that these two compounds had androgenic activity in vivo . In addition, in mature male rats, PNA and o-tolidine reduced sperm concentration and motility and increased sperm deformities, and caused atrophy of the seminiferous tubules of the testis and decreased testosterone levels. These results suggest that PNA and o-tolidine are novel environmental androgens, which bind and activate AR and have toxicological effects on male reproductive function.
研究领域:
环境科学
·
毒理学
·
内分泌学
✓ 已验证
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Huizhen Deng,Juanjuan Yin,Jinming Ma,Jingxin Zhou,Lexin Zhang,Lili Gao,Tifeng Jiao
A novel catalyst composed of Ag 3 PO 4 bridged by Ni/Ti LDH-graphene heterojunction structure was successfully prepared by a simple in-situ deposition method, which has excellent catalytic performance for 4-NP and 2-NA. Various characterizations to the samples such as XRD, SEM, TEM, STEM-EDS, XPS, TG–DSC, and UV–vis DRS were adopted. Because the ternary structure is mixed with each other to form more heterojunctions and higher specific surface area, the ternary composite Ag 3 PO 4 /Ni-Ti LDH/GO has excellent catalytic and cycle performance. Compared to the precursors Ag 3 PO 4 /GO and Ni-Ti LDH/GO, the finally as-obtained nanocomposite Ag 3 PO 4 /Ni-Ti LDH/GO degraded 4-NP and 2-NA solutions represented more dominant degradation efficiency. In addition, the pseudo-first-order rate constants of the composite catalyst for 4-NP and 2-NA are 0.178 min −1 and 0.089 min −1 , respectively. The complex and irregular surfaces of Ni-Ti LDH/GO provided an ideal carrier with abundant active sites for in-situ depositing and stabilizing of Ag 3 PO 4 NPs, formed the Ag 3 PO 4 /Ni-Ti LDH/GO hybrid possessed an acceptable catalytic performance on the degradation of azo dyes, which could be applied in the efficient treatment of wastewater from industries.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Gels
·
2024
·Vol. 10
·期 12
·808
·
IF 5
Feng Li,Ruoxi Yang,Jian Xu,Guohai Xu,Ye Wu
The concentration of small molecules reflects the normality of physiological processes in the human body, making the development of simple and efficient detection equipment essential. In this work, inspired by a facile strategy in point-of-care detection, two devices were fabricated to detect small molecules via photocurrent measurement. A linear response of the photocurrent against the concentration of the small molecules was found. In the first device, metal ions were introduced into gel substrates made by xanthan gum to enhance photocurrent response. N-phenyl-2-naphthylamine was measured when iron or manganese ions were used. L-Phenylalanine was measured when the gel was modified by samarium, iron, cerium, or ytterbium ions. L-(+)-Arabinose was detected via the gels modified by iron or holmium ions. D-(+)-Mannose was detected when the gel was modified by ytterbium, manganese, chromium, or sodium ions. L-Methionine was detected in the gels modified by samarium, zinc, or chromium ions. The second device was based on a paper sheet. A sugar-like molecule was first synthesized, which was then used to modify the paper. The detection was possible since the photocurrent showed a linear trend against the concentration of D-Trehalose. A linear fit was conducted to derive the sensitivity, whose value was found to be 5542.4. This work offers a novel, simple, and environmentally sustainable platform that is potentially useful in remote areas lacking medical devices.
研究领域:
生物医学工程
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分析化学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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