INDUSTRIAL CROPS AND PRODUCTS
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2023
·
IF 5.9
Shuzhen Yang,Min He,Dongmei Li,John Shi,Litao Peng,Liu Jinjing
The antifungal activity of essential oils is closely related to their components and contents. The study aimed to explore the structural activity of essential oil (EO) components against Diaporthe fusicola and modes of action. The results showed most of the tested compounds showed inhibitory effects on the growth of D. fusicola and carvacrol was the strongest one with half maximal effective concentration (EC 50 ) of 11.21 μL/L. The chemical structures of the tested compounds had great influences on their antifungal activity, in which the presence of CHO group, C C group or Ar-OH group in any EO components significantly increase the antifungal potency, but the increment of carbon chain length of saturated fatty aldehyde decreased antifungal activity. In order to analyze the antifungal action mode of EO components, the correlations between EC 50 and oxidation-reduction potential (ORP), cell-membrane permeability and respiration inhibition of the tested compounds were further evaluated. The results showed antifungal activities of these EO components seemed to be accomplished by increase of cell membrane permeability and inhibition of the respiration of D. fusicola . The levels of increased membrane permeability, inhibited respiration and ORP of chemicals were all significantly correlated with EC 50 . This results indicated the action mode of these EO components against D. fusicola may be associated with the increment of cell membrane permeability and respiration inhibition via disrupting redox homeostasis in fungal cells, and oxidation-reduction property could be used as a secondary indicator for screening the antifungal agent from EO components.
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CHEMICAL ENGINEERING JOURNAL
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2021
·
IF 13.273
Pan-Pan Zhao,Cong Deng,Ze-Yong Zhao,Xing-Yu Li,Hong Chen,Yu-Zhong Wang
More than 40% of the energy generated globally is consumed by residential and commercial buildings, so energy efficient materials for buildings are urgently needed at present. On-demand thermal energy storage/release using phase change materials (PCMs) can improve thermal energy utilization efficiency, however, they are facing low adaptability to temperature and easy flammability in the case of fulfilling high thermal management capacity. Herein, we report octadecylamine-based PCMs with tailor-made molecular firefighting and thermal energy management capability. These synthesized octadecylamine-based Schiff base-containing PCMs (SB-PCMs) may self-extinguish while encountering short-time fire and possess variable phase transition temperatures of 33, 42, 92, and 101 °C. Meanwhile, these SB-PCMs own high phase transition enthalpies of 161.4–183.4 J g −1 and excellent cyclic stability. When SB-PCMs as thermal energy management materials in wood plastic-based building materials, they show high adaptability to ambient temperature and excellent thermal management capability, achieving temperature regulation of 9.0 °C. Meanwhile, fire safety of the composite wood plastic materials is significantly improved. Detailed analysis confirms that the incorporated benzaldehyde with various positional substituted hydroxyl may induce noncovalent interactions (mainly hydrogen bond and π-π stacking) of SB-PCMs and further control their self-assembling processes, thus achieving multiple thermal responses of SB-PCMs; self-crosslinking charring of benzaldehyde-based Schiff base structure may retard fire spreading, therefore presenting molecular firefighting. Additional multistage thermochromic behaviors of SB-PCMs may extend their application in temperature-sensitive paint, intelligent fabric, etc. This work firstly represents a method for manipulating the multistage thermal and fire responses of PCM in the case of fulfilling high thermal energy management capacity and confirms its molecular-firefighting and energy efficient application in building materials.
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JOURNAL OF CONTROLLED RELEASE
·
2023
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IF 10.8
Tao Sun,Qinjun Chen,Zheng Zhou,Chao Li,Teng Yu,Chen Jiang
Precisely reporting the inflammatory microenvironment, which can provide important basis for disease diagnosis and progression determination, is always challenging. In this work, we develop a targeting peptide-conjugated chemiluminescent reporter (OFF), which can be recognized by in-situ circulated neutrophils once injected, and then transported to the inflamed tissues characterized with overexpressed superoxide anion (O 2 − ), assisted by the chemotaxis natural of neutrophils. Subsequently, the chemiluminescent probe can particularly respond to O 2 − to release the caged photons (ON) for visualizing inflammatory diseases such as subcutaneous tumor, colorectal cancer peritoneal metastasis (CCPM), ear swelling and kidney failure. The chemiluminescent probe provides a reliable tool to early detect inflammation and precisely excise micrometastatic lesions under optical guidance. This study provides a potential approach for improving the performance of luminophore in advanced bioimaging applications.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Zhen-Long Wu,Di Shi,Li Huang,Wen-Ying He,Xiang-Ying Sun,Bin Liu,Jiang-Shan Shen
A highly selective and sensitive probe 1b was successfully developed for detecting Hg 2+ ions in mixed aqueous medium with a “turn on” fluorescence mode, via a series of structural optimization of probes. These probes could be easily synthesized by one-step condensation reactions between o -phenylenediamine or 2, 3-diaminonaphthalene and o (salicylaldehyde), m , or p- hydroxybenzaldehyde. Introducing a certain amount of Hg 2+ ions the fluorescence of probes bearing one or two salicylaldehyde moieties including probes 1a, 1b, and 4 could be turned on. The fluorescent response is likely due to the well matching between Hg 2+ ions size and the geometric structure of probes, resulting in that probes bearing salicylaldehyde moiety are mostly favorable for binding with Hg 2+ ions by way of 1:1 molar ratio. These bindings likely facilitate excited state internal proton transfer (ESIPT) or ESIPT coupled aggregation-induced enhancement of emission (AIEE) process. Considering the sensitivity and the potential of practical application, probe 1b was chosen to establish a fluorescent enhancement sensing system towards Hg 2+ ions over other competing metal ions, with excellent limit of detection of 12.5 ppb.
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JOURNAL OF MOLECULAR STRUCTURE
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2017
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IF 1.753
Guanfan Chen,Mengzhuo Tang,Xiufang Fu,Fenmin Cheng,Xianghua Zou,Jingpei Wang,Rongjin Zeng
Sulfide anions are not only generated as a byproduct from industrial processes but also as a crucial kind of element in biological systems. Therefore, fluorescent probes for detecting sulfide anion with sensitive and selective characters are highly popular. In this study, we report a highly sensitive and selective fluorescent sensor M1 for detection of sulfide anion based on the steric hindrance effect, where the recognition unit, dinitrobenzenesulfonate ester group is linked to aromatic ortho -position in the porphyrin , and correspondingly the fluorescence of fluorescein is efficiently quenched. Compared with the sensors with recognition unit linked to the other aromatic positions, the fluorescent sensor M1 has a lower fluorescence background. Furthermore, the corresponding fluorescence responses ( F/F0 ) of M1 for mercapto amino-acid GSH, Hcy and Cys, were all far lower than the relative fluorescence ratio F/F0 values for S 2− . It means that M1 is sensitive and selective to detection of S 2− , and has an anti-disturbance ability to the biologically-relevant thiols, GSH, Hcy and Cys, and has the prospect of application in the exact detection of sulfide anions in living organisms. This approach offers some useful insights for realizing sensitive and selective fluorescent turn-on sensing in the detection assays for other analytes.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2017
·Vol. 409
·期 10
·2531-2537
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IF 3.431
Cheng Hao,Wu Shubin,Huang Jinbao,Zhang Xiaohua
Although o -quinonemethide (6-methylene-2,4-cyclohexadien-1-one) has been proposed as a key intermediate in char formation during the pyrolysis of guaiacol (2-methoxyphenol), direct evidence of this (e.g., spectroscopic data) has not yet been provided. Using in situ FTIR spectroscopy, the pyrolysis of guaiacol was investigated from 30 °C to 630 °C at 40 °C/min. The IR profiles showed direct evidence of o -quinonemethide production at about 350 °C, which vanished rapidly at around 420 °C in the vapor phase, indicating char formation. In addition, at 400 °C, salicyl aldehyde was observed, which decomposed slowly at about 500 °C. In combination with the known products of guaiacol pyrolysis, these results allowed the major reaction pathways of guaiacol pyrolysis to be discerned. Density functional theory calculations were performed, and the results were found to be in good agreement with the experimentally obtained IR profiles. These findings provide guidance on how to suppress secondary reactions of guaiacol during lignin pyrolysis.
On-line analysis of pyrolysis process of guaiacol using in situ FTIR
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FLUID PHASE EQUILIBRIA
·
2015
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IF 2.2
Hao Wu,Jing Zhu,Yiwei Wang,Chengwei Chang,Junsu Jin
To understand the phase behavior of 3-hydroxybenzaldehyde (3-HBA) and the solubility effect of 3-HBA and 4-hydroxybenzaldehyde (4-HBA) on each other in supercritical carbon dioxide (SCCO 2 ), the equilibrium solubility of 3-HBA and its mixture with 4-HBA, was measured in SCCO 2 binary system (comprising of a solute and SCCO 2 ) and ternary system (comprising of two solutes and SCCO 2 ) at temperature and pressure given in range of 308–328 K and 11.0–21.0 MPa respectively. Comparing the solubility of 3-HBA and 4-HBA between in the binary system and ternary system, it was found that the equilibrium solubility of both 3-HBA and 4-HBA was enhanced in the ternary system due to the molecular interaction. The experimental data were correlated by Chrastil, Mendez-Santiago and Teja (M-S-T), Sovova, their modified models, and Zhu et al. model. Also a new model was deduced and established based on the Chemistry Association Theory and was verified by 636 groups of solubility data. The correlated results indicated that the new model obtained a less deviation than other models, including the modified Chrastil model, the modified M-S-T model, the modified Sovova model, and Zhu et al. model, all of which have same adjustable parameters.
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PLoS One
·
2015
·Vol. 10
·期 9
·e0138578
·
IF 3.234
Feng Yu,Yu-Long Jia,Hui-Fang Wang,Jing Zheng,Yi Cui,Xin-Yu Fang,Lin-Min Zhang,Qing-Xi Chen
In the present study, new Schiff’s base derivatives: (Z)-4-amino-5-(2-(3- fluorobenzylidene)hydrazinyl)-4H-1,2,4-triazole-3-thiol (Y 1 ), (Z)-3-((2-(4-amino-5- mercapto-4H-1,2,4-triazol-3-yl)hydrazono)methyl)phenol (Y 2 ), (Z)-2-((2-(4-amino-5- mercapto-4H-1,2,4-triazol-3-yl)hydrazono)methyl)phenol (Y 3 ) and 3-((Z)-(2-(4- (((E)-3-hydroxybenzylidene)amino)-5-mercapto-4H-1,2,4-triazol-3-yl)hydrazono)methyl)phenol (Y 4 ) were synthesized and their structures were characterized by LC-MS, IR and 1 H NMR. The inhibitory effects of these compounds on tyrosinase activites were evaluated. Compounds Y 1 , Y 2 and Y 3 showed potent inhibitory effects with respective IC 50 value of 12.5, 7.0 and 1.5 μM on the diphenolase activities. Moreover, the inhibition mechanisms were determined to be reversible and mixed types. Interactions of the compounds with tyrosinase were further analyzed by fluorescence quenching, copper interaction, and molecular simulation assays. The results together with the anti-tyrosinase activities data indicated that substitution on the second position of benzene ring showed superior ant-ityrosinase activities than that on third position, and that hydroxyl substitutes were better than fluorine substitutes. In addition, two benzene rings connecting to the triazole ring would produce larger steric hindrance, and affect the bonding between tyrosinase and inhibitors to decrease the inhibitory effects. The anti-tyrosinase effects of these compounds were in contrast to their antioxidant activities. In summary, this research will contribute to the development and design of antityrosinase agents.
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2013
·Vol. 51
·期 11
·2425-2437
·
IF 3.543
Jie Shen,Ying Zhang,Wenqiu Chen,Wenhao Wang,Zushun Xu,Kelvin W. K. Yeung,Changfeng Yi
Novel pyridine-containing hyperbranched polyimides (HBPIs) were synthesized by using a new triamine 2,4,6-tris[3-(4-aminophenoxy)phenyl]pyridine with prolonged chain segments, ether linkage and meta -linked units as a BB′ 2 -like monomer, various commercial aromatic dianhydrides as A 2 monomers. Most of the obtained HBPIs were readily soluble in common organic solvents such as N , N -dimethylformamide, N , N -dimethylacetamide, N -methyl-2-pyrrolidone, m -Cresol, and so forth. Meanwhile, they also had good thermal stability with the glass transition temperatures ( T g s) all above 210 °C, the temperature at 10% weight loss of 537.1–574.4 °C in nitrogen atmosphere. Strong and flexible HBPI films were obtained, which had good mechanical properties with tensile strengths of 83.3–95.8 MPa, tensile modulus of 1.82–2.43 GPa and elongations at break of 4.84–6.98%. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 2425–2437
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HIGH PERFORMANCE POLYMERS
·
2017
·
IF 1.179
Xiaoli Wu,Chunlei Dong,Alvianto Wirasaputra,Haohao Huang,Shumei Liu,Jianqing Zhao,Yi Fu
High mechanical properties and flame retardancy of epoxy are important for its applications. A novel star-shaped flame-retardant 5,10-dihydro-phenohphosphazine-10-oxide functioned triazine (TRIDPPA) with high efficiency is synthesized, and its structure is characterized. TRIDPPA is used as the co-curing agent for diglycidyl ether of the bisphenol A/4,4-diaminodiphenyl methane system. The introduction of TRIDPPA greatly improves the flame retardancy of the cured epoxy resins. The epoxy resin (ER)/TRIDDPA1.0 resin acquires a limiting oxygen index value of 30.7% and UL-94 V-0 rating when the mass fraction of TRIDDPA is 1.0 wt% with only 0.086 wt% of phosphorus content. The cross-link density of ER/TRIDDPA1.0 is increased, and the glass transition temperature is improved by 5°C. Besides, tensile strength and toughness of ER/TRIDDPA1.0 are also enhanced.
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THERMOCHIMICA ACTA
·
2015
·
IF 2.184
Junsu Jin,Jiarong Sang,Xing Fan,Chengwei Chang,Hao Wu
The static flow method coupled with gas chromatography analysis was used to measure the solubilities of pure 4-hydroxybenzaldehyde, 3-hydroxybenzaldehyde and their mixture with equal molar ratio in subcritical 1,1,1,2-tetrafluoroethane (R134a) at 308, 318, 328 K and 5.0–15.0 MPa. Comparison of the solubility of each solute in the binary subcritical R134a system with that in the ternary system was made. Furthermore, the effect of molecular structure on the solubility was discussed, and the improvement effect factor ( μ ) and separation factor (SF) of each solid solute in the ternary system had been investigated. In addition, the solubility enhancement factor ( δ ) had been defined and calculated to compare the solubility of the same solute in subcritical R134a with that in supercritical carbon dioxide. The solubility data of pure solute in the binary subcritical R134a system were correlated by Chrastil and Méndez-Santiago and Teja (MST) models, while the solubility data in the ternary system were correlated by their modified models (Chrastil-G and MST-S), Sovová and its modified models. All the calculated solubility data showed satisfactory agreements with the experimental one.
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Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2025
·
IF 4.6
Wanting Li,Xilang Jin,Xuehao Ma,Bin Huang,Xinyu Zhang,Xiao Li,Qingfa Si,Weixing Chen
To minimize the harmful effects of ultraviolet (UV) radiation on the skin and eyes, the development of protective films that block UV rays and high-energy blue light (HEBL) while maintaining a high transmittance rate of visible light has become imperative. In this work, hyperbranched polyethyleneimine (hPEI) and hydroxybenzaldehyde were utilized as precursors to prepare carbon dots (CDs) with maximum absorption wavelengths in both the UV and HEBL bands, as well as excellent tolerance and acid/base resistance. In addition, CDs were incorporated into the polyvinyl alcohol (PVA) matrix to form CDs shielding films. The primary mechanism is to utilize C N in CDs to form hydrogen bonds with OH in PVA to fix CDs in PVA. These films achieved maximum UV blocking efficiencies exceeding 98.87 % and HEBL blocking efficiencies over 85.08 %, while the highest visible light transmittance reached 70 %. Furthermore, these films were applied to a light-emitting diode (LED), adjusting the color temperature from cool to warm tones by blocking the 400–470 nm blue light range. This work not only introduces a novel strategy for preparing bifunctional UV absorbers but also paves the way for the advancement of health-oriented lighting solutions.
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