ANALYTICAL LETTERS
·
2024
·
IF 1.6
Yan Chen,Yiwei Sun,Shuyan Qi,Li Zhang,Ming Yin,Xiuxia Wei,Yuting Luo,Dongpo Xu
Yolk-shell SnO2 mesoporous double-layer nanotubes were synthesized in one-step by single nozzle electrospinning. Compared with the traditional electrospinning using polyvinylpyrrolidone (PVP) as the precursor polymer to obtain the single nanotube material, two PVPs (PVPK88-96 and PVPK23-27) with different molecular weights in solution coupled with Sn2+ easily form the core-shell structure nanofiber through phase separation. The yolk-shell double-layer SnO2 nanotubes were obtained after calcination at 600 °C for 2 h. The yolk-shell SnO2 mesoporous double-layer nanotube is a promising sensing material toward 3-hydroxy-2-butanone as it shows high sensitivity, cycling stability, and selectivity. Moreover, the response and recovery times of the yolk-shell SnO2 mesoporous double-layer nanotubes toward 1 ppm 3-hydroxy-2-butanone were 122 s and 117 s.
研究领域:
材料科学
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化学传感器
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纳米技术
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DOI
高影响因子
ACS Sensors
·
2023
·
IF 8.9
Siqi Xie,Cheng Zhao,Jiabin Shen,Jing Wei,Haiquan Liu,Yingjie Pan,Yong Zhao,Yongheng Zhu
Listeria monocytogenes, which is abundant in environment, can lead to many kinds of serious illnesses and even death. Nowadays, indirectly detecting the metabolite biomarker of L. monocytogenes, 3-hydroxy-2-butanone, has been verified to be an effective way to evaluate the contamination of L. monocytogenes. However, this detection approach is still limited by sensitivity, selectivity, and ppb-level detection limit. Herein, low-cost and highly sensitive and selective 3-hydroxy-2-butanone sensors have been proposed based on the bimetallic AuPd decorated hierarchical flower-like WO3 nanospheres. Notably, the 1.0 wt % AuPd-WO3 based sensors displayed the highest sensitivity (Ra/Rg = 84 @ 1 ppm) at 250 °C. In addition, the sensors showed outstanding selectivity, rapid response/recovery (8/4 s @ 10 ppm), and low detection limit (100 ppb). Furthermore, the evaluation of L. monocytogenes with high sensitivity and specificity has been achieved using 1.0 wt % AuPd-WO3 based sensors. Such a marvelous sensing performance benefits from the synergistic effect of bimetallic AuPd nanoparticles, which lead to thicker electron depletion layer and increased adsorbed oxygen species. Meanwhile, the unique hierarchical nanostructure of the flower-like WO3 nanospheres benefits the gas-sensing performance. The AuPd-WO3 nanosphere-based sensors exhibit a particular and highly selective method to detect 3-hydroxy-2-butanone, foreseeing a feasible route for the rapid and nondestructive evaluation of foodborne pathogens.
研究领域:
材料科学
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生物医学工程
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环境监测
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产品关联
DOI
PubMed
高影响因子
CyTA-Journal of Food
·
2025
·
IF 1.7
Han Zhao,Xiaohui Duan,Siqi Xie,Lili Cheng,Fei Wang,Wenjuan Xu,Yaolei Zhang,Weiyi Zhang,Cheng Zhao
Listeria monocytogenes is a foodborne pathogenic bacterium that can survive under a wide range of temperature and pH conditions, with a mortality rate of up to 20% −30%. One emerging and validated method of indirectly assessing Listeria monocytogenes in food is detecting 3-hydroxy-2-butanone gas. In this study, WO3 nanoflowers (a diameter of 2.8 µm) and two different hierarchical structures of WO3 were successfully synthesized. XRD, BET, SEM, and TEM were applied to characterize their morphology, microstructure, catalytic structure, and specific surface area. For assessing their gas sensing performances toward 3-hydroxy-2-butanone, a series of gas sensitivity indicators were purposefully measured. The results indicated that WO3 nanoflowers had the best gas sensing performance including high sensitivity (81 @ 20 ppm), rapid response-recovery time (4 s/9 s), low LOD (1 ppm) and good stability. Moreover, by analysing the various characterization results of these materials, the sensitivity mechanism was explained in detail as well.
研究领域:
微生物学
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材料科学
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食品科学
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产品关联
DOI
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 8
·719
·
IF 4.4
Xueyan Li,Zeyi Wu,Xiangyu Song,Denghua Li,Jiajia Liu,Jiatao Zhang
Nowadays, metal oxide semiconductor gas sensors have diverse applications ranging from human health to smart agriculture with the development of Internet of Things (IoT) technologies. However, high operating temperatures and an unsatisfactory detection capability (high sensitivity, fast response/recovery speed, etc.) hinder their integration into the IoT. Herein, a ternary heterostructure was prepared by decorating WO3nanoplates with Au and SnO2nanoparticles through a facial photochemical deposition method. This was employed as a sensing material for 3-hydroxy-2-butanone (3H-2B), a biomarker ofListeria monocytogenes. These Au/SnO2–WO3nanoplate-based sensors exhibited an excellent response (Ra/Rg= 662) to 25 ppm 3H-2B, which was 24 times higher than that of pure WO3nanoplates at 140 °C. Moreover, the 3H-2B sensor showed an ultrafast response and recovery speed to 25 ppm 3H-2B as well as high selectivity. These excellent sensing performances could be attributed to the rich Au/SnO2–WO3active interfaces and the excellent transport of carriers in nanoplates. Furthermore, a wireless portable gas sensor equipped with the Au/SnO2–WO3nanoplates was assembled, which was tested using 3H-2B with known concentrations to study the possibilities of real-time gas monitoring in food quality and safety.
研究领域:
传感器技术
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食品安全
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纳米材料科学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Ding Wang,Lifeng Deng,Haijie Cai,Jialin Yang,Liping Bao,Yongheng Zhu,Xianying Wang
As a foodborne bacterium, Listeria monocytogenes (LM) can cause serious diseases and even death to weak people. 3-Hydroxy-2-butanone (3H-2B) has been proven to be a biomarker for exhalation of LM. Detection of 3H-2B is a fast and effective method for determining whether the food is infected. Herein, we present an excellent 3H-2B gas sensor based on bimetallic PtCu nanocrystal modified WO3 hollow spheres. The structure and morphology of the PtCu/WO3 were characterized, and their gas sensitivities were measured by a static testing method. The results showed that the sensor response of WO3 hollow spheres was enhanced by about 15 times after modification with bimetallic PtCu nanocrystal. The maximum response value of the PtCu/WO3 sensor to 10 ppm 3H-2B is as high as 221.2 at 110 °C. In addition, the PtCu/WO3 sensor also exhibited good selectivity to 3H-2B, fast response/recovery time (9 s/28 s), and low limit of detection (LOD < 0.5 ppm). Furthermore, the sensitivity mechanism was studied by monitoring the reaction products by gas chromatography–mass spectrometry. The excellent gas-sensing performance can be attributed to the synergy between PtCu and WO3, including the unique spillover effect of O2 on PtCu nanoparticles, the regulated depletion layer by p-type CuxO to n-type WO3, and their selective catalysis to 3H-2B. Hence, this work offers the rational design and synthesis of highly efficient sensitive materials for the detection of LM for food security.
研究领域:
材料科学
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化学传感器
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食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2017
·Vol. 7
·期 2
·25
·
IF 3.553
Xiang-Nan Xu,Xiao-Na Guan,Hui-Hua Zhou,Yue-Feng Zhu
3-Hydroxy-2-naphthoic acid hydrazide (HNH), a new reductant and modifier, was applied to reduce and modify graphene oxide (GO) in a one-step process. The obtained HNH reduced graphene oxide (HNH-rGO) was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), Raman spectroscopy, X-ray photoelectron spectroscopic (XPS) and Fourier transform infrared spectra (FTIR). The results demonstrated that GO was successfully reduced to graphene and the surface of HNH-rGO was grafted with HNH. The interlayer space was increased from 0.751 nm to 1.921 nm, and its agglomeration was much more attenuated compared with GO. HNH-rGO/polypropylene and graphene/polypropylene composites were synthesized through melt-blending method. The viscosity was enhanced with increased addition of graphene and surface modified graphene demonstrated stronger rheological behavior improving effect than the untreated graphene.Keywords:graphene;reduction;surface modification;nanocomposites
研究领域:
材料科学
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化学工程
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
·
IF 13.2
Xing-Yu Wang,Ping-Ping Liu,Hai-Jie Cai,Miao-Miao Li,Chun-Hui Deng,Yong Zhao,Zhao-Huan Zhang,Yong-Heng Zhu
Biomarkers detection of foodborne pathogens through gas sensors provides a promising method to ensure food safety. However, rapidly and accurately identifying ultra-low concentration bacterial biomarkers is still an urgent task. In this study, PdRh bimetallic-loaded α-Fe 2 O 3 nanospindles with sufficient exposed surface and high surface activity are designed to achieve sensitive detection of the Listeria monocytogene biomarker s : 3-hydroxy-2-butanone. α-Fe 2 O 3 nanospindles with high exposure surfaces were prepared by modulating the axial diameter ratio. Then PdRh bimetals were uniformly introduced to regulate the surface activity of α-Fe 2 O 3 nanospindles. Compared to pure Fe 2 O 3 , the result 1.5 wt% PdRh-Fe 2 O 3 nanospindle exhibits significantly improved sensitivity and selectivity in detecting 3-hydroxy-2-butanone, characterized by a reduced operating temperature from 240°C to 150 °C, high sensitivity (R a /R g = 148.4, 50 ppm), impressive response/recovery time (7/10 s), low detection limit (200 ppb), notable selectivity, and great stability over a test period exceeding 30 days. Mechanism studies through ex/in-situ characterization and density functional theory calculations (DFT) reveal that the dramatic sensing performance advancement is mainly due to the morphology optimization, bimetallic activation, and their synergistic effects, leading to the increased surface active species, enhanced oxygen mobility, and the reduced activation energy. Furthermore, high-sensitivity detection of Listeria monocytogenes in actual samples is also achieved by using 1.5 wt% PdRh-Fe 2 O 3 nanoneedles-based sensor, indicating its significant potential for non-destructive testing applications in the food industry and opening new avenues for the rapid detection of Listeria monocytogenes .
研究领域:
材料科学
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食品科学
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生物医学工程
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产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMISTRY
·
2022
·Vol. 40
·期 17
·2054-2060
·
IF 5.56
Mengping Chen,Lang Lang,Lei Chen,Xiaomei Wang,Cen Shi,Qiwen Sun,Yigong Xu,Juan Diwu,Shuao Wang
Comprehensive Summary The environmental contamination of uranium will occur in scenarios such as nuclear accidents and leakage from nuclear waste storage sites, which eventually leads to the internal uranium exposure of people, causing consequential injuries of renal failure, osteosarcoma, etc . The development of uranyl specific chelating agents that could sequester uranium in vivo is in urgent need and is important for the safe and efficient development of nuclear industry. Metal organic frameworks (MOFs) already serve as efficient uranium depletion materials in solutions of a wide range of pH and ionic strength for nuclear fuel recycling, uranium extraction from seawater, as well as environmental decontamination. Herein, a chromium-based nano-metal organic framework (nano-MOF) functionalized interiorly with 3,2-HOPO ligands, MIL-101-HOPO, is rationally synthesized. In vitro adsorption experiments show that MIL-101-HOPO exhibits high adsorption selectivity and fast adsorption kinetics for uranyl. The results of in vivo uranyl decorporation assays reveal that MIL-101-HOPO with the decoration of HOPO ligands on the interior wall exhibits significantly increased uranyl removal ratio in kidneys comparing to the pristine nMOFs, and is more effective than the clinically used ZnNa 3 -DTPA. All those results corroborate the interior functionalization of MOFs as an efficient strategy to develop promising uranyl decorporation agents.
研究领域:
环境科学
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材料科学
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核工程
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毒理学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2022
·
IF 5.895
Chunle Wei,Xiong Yang,Shaojie Shi,Lian Bai,Deyu Hu,Runjiang Song,Baoan Song
3-Hydroxy-2-oxindole motif constitutes a core structure in numerous natural products and imparts notable biological activities. Here, we describe the design and synthesis of four series of novel 3-substituted-3-hydroxy-2-oxindole derivatives containing sulfonamide moiety along with their antiviral activities against potato virus Y (PVY). Compound 10b displayed optimal antiviral activity and superior anti-PVY activity compared with the lead compound and commercial Ningnanmycin in terms of curative and protective effects. Additionally, 10b considerably inhibited PVY systemic infection in Nicotiana benthamiana. Physiological and biochemical analyses revealed that the activities of the four crucial defense-related enzymes increased in the tobacco plant following treatment with 10b. RNA-sequencing analysis revealed that 10b substantially induced the upregulation of 38 differentially expressed genes, which were enriched in the photosynthesis pathway. These findings suggest that 10b is a promising antiviral agrochemical that can effectively control PVY infection and trigger plant host immunity to develop virus resistance. This study provides novel molecular entities and ideas for developing new pesticides.
研究领域:
有机化学
·
药物化学
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植物病理学
·
分子生物学
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农学
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
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2021
·
IF 4.32
Yang Mu,Fuyin Zhang,Ning Li,Shanshan Pi,Ang Li,Qing Hong,Jian He,Jiguo Qiu,Jiandong Jiang
Dipicolinic acid (DPA) is a widely distributed pyridine derivative containing two carboxylate groups. However, the catabolism of DPA mediated by microorganisms are rarely reported. Alcaligenes faecalis strain JQ135, previously isolated in our lab, was able to degrade various pyridine derivatives, including nicotinic acid (NA). In this study, it was found that strain JQ135 could utilize DPA as the sole carbon and nitrogen source for growth and degrade 1.8 mM (300 mg/L) DPA to a non-detectable level within 12 h. The catabolism of DPA by strain JQ135 extracted two intermediates, i.e., 3-hydroxy-2,6-dipicolinic acid and 4-imino-pent-2-enedioic acid. Moreover, deletion of the key genes essential for NA catabolism (such as moaCDEBmoeA and maiA ) did not affect DPA catabolism, indicating that the maleamate pathway and molybdenum cofactor are not involved in the DPA catabolism by strain JQ135. This study will provide insights into the bacterial catabolism of DPA.
研究领域:
微生物学
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环境科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Shao-Kang Ju,Li-Juan Yue,Jian-Yong Yuan,Fei-Long Gong,Ke-Feng Xie,Xuan-Yu Yang,Shao-Ming Fang,Yong-Hui Zhang
Defect sites in heterostructures play a vital role in optimizing interfacial charge separation efficiency and carrier migration behavior, which enhance surface reaction dynamics. However, the effect of defect sites on modulation of electronic structure and oxygen activation is still ambiguous. Herein, we successfully construct in-plane ZnIn 2 S 4 /In 2 O 3 heterostructures by partial in-situ oxidation strategy and the surface properties can be precisely tuned by treating at individual temperatures. Notably, the in-plane ZnIn 2 S 4 /In 2 O 3 heterostructure which is treated in air at 425 °C exhibits outstanding sensing performance towards acetoin (R a /R g = 248.6 for 50 ppm acetoin at 180 °C), a biomarker of Listeria monocytogenes, with rapid response and recovery dynamic (18/183 s), along with excellent reliability and sensing stability. Detailed characterization and DFT calculation indicate that in-plane heterostructures possess numerous grain boundaries, thereby modulating the p-orbitals electronic structure of oxygen atom and promoting the formation of reactive oxygen species (O − (ad)). Moreover, the built-in electric field further also facilitates the electron transfer, further contributing to the enhanced sensing performance for 3-hydroxy-2-butanone.
研究领域:
材料科学
·
纳米技术
·
传感器
·
表面化学
·
电子器件
·
固体物理
·
分析化学
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生物传感器
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2014
·
IF 3.107
Jian Xiao,Qiang Zhang,Yu-Qi Gao,Jiang-Jiang Tang,An-Ling Zhang,Jin-Ming Gao
Two new metabolites, an α-pyridone derivative, 3-hydroxy-2-methoxy-5-methylpyridin-2(1H)-one (1), and a ceramide derivative, 3-hydroxy-N-(1-hydroxy-3-methylpentan-2-yl)-5-oxohexanamide (2), and a new natural product, 3-hydroxy-N-(1-hydroxy-4-methylpentan-2-yl)-5-oxohexanamide (3), along with 15 known compounds including chaetoglobosin C (7) and chaetoglobosin F (8) were isolated from the solid culture of the endophytic fungus Botryosphaeria dothidea KJ-1, collected from the stems of white cedar (Melia azedarach L). The structures were elucidated on the basis of spectroscopic analysis (1D and 2D NMR experiments and by mass spectrometric measurements), and the structure of 1 was confirmed by X-ray single-crystal diffraction. These metabolites were evaluated in vitro for antimicrobial, antioxidant, and cytotoxicity activities. Pycnophorin (4) significantly inhibited the growth of Bacillus subtilis and Staphyloccocus aureus with equal minimum inhibitory concentration (MIC) values of 25 μM. Stemphyperylenol (5) displayed a potent antifungal activity against the plant pathogen Alternaria solani with MIC of 1.57 μM comparable to the commonly used fungicide carbendazim. Both altenusin (9) and djalonensone (10) showed markedly DPPH radical scavenging activities. In addition, stemphyperylenol (5) and altenuene (6) exhibited strong cytotoxicity against HCT116 cancer cell line with a median inhibitory concentration (IC50) value of 3.13 μM in comparison with the positive control etoposide (IC50 = 2.13 μM). This is the first report of the isolation of these compounds from the endophytic B. dothidea.
研究领域:
药理学
·
微生物学
·
生物化学
·
有机化学
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植物科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）