BIOMACROMOLECULES
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2023
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IF 6.2
Hongyang Song,Lei Xing,Wentao Liu,Xue Wang,Zhaosheng Hou,Yue Wang,Zhenhao Zhang,Yiming Li,Tianduo Li,Xiaolong Wang,Hui Chen,Shu Xing,Jing Xu
Uncontrolled bleeding in emergency situations is a great threat to both military and civilian lives, and an ideal hemostat for effectively controlling prehospital hemorrhage is urgently needed but still lacking. Although hemostatic hydrogels are promising for emergency hemostasis, they are currently challenged by either the mutual exclusion between a short gelation time and strong adhesive network or the insufficient functionality of ingredients and complicated operations for in situ curing. Herein, an extracellular matrix biopolymer-based and multifunctional hemostatic hydrogel that simultaneously integrates rapid thermoresponsive gelation, robust wet adhesion, and ease of use in emergencies is rationally engineered. This hydrogel can be conveniently used via simple injection and achieves instant sol–gel phase transition at body temperature. Its comprehensive performance could be facilely regulated by tuning the proportions of components, and the optimal performance (gelation time 6–8 s, adhesion strength 125 ± 3.6 kPa, burst pressure 282 ± 4.1 mmHg) is established due to the coordinated enhancement of the photo-cross-linking pretreatment and the hydrophilic–hydrophobic balance among various interactions in the hydrogel system. Additionally, it exhibits significant coagulation effect in vitro and enables effective hemostasis and wound healing in vivo. This work provides a promising platform for versatile applications of hydrogel-based materials, including emergency hemostasis.
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高影响因子
ChemistrySelect
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2023
·Vol. 8
·期 34
·e202301948
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IF 2.1
Hai-Bo Wu,Xian-Tai Zhou,Xiao-Wu Zhou,Yan-Xiong Fang
Graphical Benzoic acid has been proved to be an efficient catalyst for the ring-opening polymerization of ϵ-caprolactone under mild conditions. A monomer-activated ring-opening polymerization mechanism mediated by benzoic acid was proposed. It is expected to realize the one-step preparing of poly (ϵ-caprolactone) through the direct aerobic oxidation of cyclohexanone. The development of a feasible industrial method for poly(ϵ-caprolactone) (PCL) preparation is great of significant and challenging. The bulk ring-opening polymerization of ϵ-caprolactone (ϵ-CL) using various organic acid catalysts and benzyl alcohol (BnOH) as the initiator was developed. Benzoic acid (BA) has been proved to be an efficient catalyst for the ROP of ϵ-CL under mild conditions. The conversion of ϵ-CL to PCL was 84.7 % under the optimized reaction conditions, with number-average molecular weight ( M n ) and dispersity (PDI) of 7700 g/mol and 1.25, respectively. Moreover, a monomer-activated ring-opening polymerization mechanism mediated by benzoic acid was proposed. Overall, this work is expected to provide a feasible industrial method for the preparation of PCL using benzoic acid as organocatalyst.
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ANALYTICA CHIMICA ACTA
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2018
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IF 5.123
Kunhao Yang,Zhongqiu Li,Yueguang Lv,Chuyi Yu,Peilong Wang,Xiaoou Su,Li Wu,Yujian He
An electrochemical aptasensor for ultrasensitive detection of hydroxylated polychlorinated biphenyl (OH-PCB) was developed. In this work, the sulfydryl aptamer selected for OH-PCB was easily immobilized on the surface of the modified glassy carbon electrode via Au-S bond due to incorporation of gold nanoparticles/poly dimethyl diallyl ammonium chloride-graphene composite. The fabrication process of the electrochemical aptasensor was characterized by electrochemical impedance spectroscopy and cyclic voltammetry . The peak currents obtained by differential pulse voltammetry decreased with the increasing of OH-PCB concentrations. The current responded approximately logarithmically to the OH-PCB concentration ranging from 2.9 × 10 −11 M to 2.9 × 10 −7 M with excellent linear correlation performance. The detection limit of OH-PCB was estimated as low as 5.3 × 10 −12 M. The developed method had been successfully applied to analyzing lake water. Particularly, the method of the electrochemical aptasensor opens up a new perspective in environmental monitoring by the aptamer identification.
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JOURNAL OF CHROMATOGRAPHY A
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2025
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IF 4
Fuyang Gu,Xiaoyan Wang,Jinmei Du,Yang Jiang,Dagang Miao,Yanmei Qu,Dongyan Shao,Guowei Xiao,Changhai Xu
Cationic bleaching activators can effectively achieve low-temperature bleaching in hydrogen peroxide system, but at the same time, self-hydrolysis reaction will occur to affect the low-temperature bleaching effect, and the complex hydrolysis pathways of cationic bleaching activators are still elusive. In this paper, the hydrolysis reaction pathways, mechanisms, rates and kinetics of cationic bleaching activators N-[4-(triethylaminomethyl)benzoyl]lactam chlorides (TBLCs) with different lactam leaving groups were investigated in depth by liquid chromatography-mass spectrometry (LC-MS) and high-performance liquid chromatography (HPLC). Specifically, we characterized the hydrolysis products by LC-MS and further quantified the hydrolysis products using HPLC, demonstrating that the hydrolysis can take place via two pathways, generating chain-breaking products and ring-opening products, and that both react at different rates depending on the different lactam leaving groups. Notably, the quantitative results showed that the chain-breaking products were always larger than the ring-opening products, and the chain-breaking products were ineffective for bleaching, which was the main reason for the decrease in the bleaching performance of TBLCs. The mechanism of hydrolysis is discussed and the reaction rate was determined to follow first-order kinetics using HPLC. We have successfully delineated the complete transformation pathway of the hydrolysis reaction using this method, providing valuable information for the future preparation of novel bleaching activators and the reduction of this reaction.
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MICROCHEMICAL JOURNAL
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2024
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IF 4.9
Fuyang Gu,Ziting Ma,Yannuo Liu,Xiaoyan Wang,Peng Du,Yang Jiang,Guowei Xiao,Yanmei Qu,Changhai Xu
The blend of hydrogen peroxide (H 2 O 2 ) and N-[4-(triethylaminomethyl)benzoyl]caprolactam chloride (TBCC) boosts exceptional bleaching efficacy under low temperature and weak alkaline conditions, greatly reducing energy consumption. Nevertheless, the intricate perhydrolysis pathway of TBCC within a hydrogen peroxide solution and its subsequent impact on the whiteness of fabrics during this process have remained elusive. This study presents an integrated analytical methodology that harnesses ultraviolet spectrophotometry, fluorescent probes, confocal fluorescence microscopy, and liquid chromatography-mass spectrometry (LC-MS) to examine the pivotal aspects of the cotton fabric bleaching process. Specifically, we focus on the detection and quantification of the critical product N-4-(triethylammoniomethyl)peracetic acid (TPA) in the bleaching reaction. The research detected and quantified TPA, while emphasizing that insufficient concentrations and abbreviated durations of TPA significantly compromise the bleaching efficacy. Notably, variations in the TPA generation rate under different conditions revealed why TBCC exhibits exceptional bleaching performance under low-temperature and mildly alkaline conditions. This insight provides new perspectives and valuable insights into the critical factors influencing the bleaching process. The method is also applicable to other bleaching activators, and by controlling these factors in conjunction with actual conditions, it is possible to effectively reduce energy waste and provide valuable information for optimizing future practices in the field of bleaching.
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EUROPEAN POLYMER JOURNAL
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2024
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IF 5.8
Haiyue Wang,Liying Guo,Rongrong Zheng,Hongshuang Guo,Bing Fang,Jingyu Chai
The escalating global concern surrounding lithium battery electrolyte (LBE) arises from the substantial accumulation of discarded, hazardous, and valuable materials. While there has been extensive documentation on electrolyte recovery, research on harnessing the potential of solvent carbonates remains relatively sparse. To tackle this issue, we pioneered the development of three innovative metal anion-cation coordination ionic liquid catalysts. These catalysts were meticulously crafted to facilitate the synthesis of polycarbonate from spent LBE carbonate. Our approach involved intricate reactions between organic cations and inorganic anions with various metal compounds, resulting in synergistic catalytic effects. Comprehensive characterization unequivocally verified the intended chemical structure and thermal stability. Through systematic optimization of reaction conditions, our efforts yielded exceptional outcomes. The standout performer among the 1,3-(p-toluic acid Zinc Salt)Im ZnCl 3 achieved an impressive conversion rate and a robust yield. The catalyst demonstrated exceptional efficiency, selectivity, and degree of polymerization, offering auspicious avenues for future applications.
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Journal of Environmental Chemical Engineering
·
2025
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IF 7.2
Fangfang Zhang,Yingxuan Wen,Falong Shan,Jingru Dou,Shougui Wang,Jipeng Dong,Guanghui Chen,Fei Gao
In this study, a sequence of pyridine-based hypercrosslinked ionic polymers (HIP-IBy, HIP-IByCA and HIP-IByBA) as heterogeneous catalysts were prepared using a two-step method for the CO 2 cycloaddition reaction. The synthesized pyridine-based HIPs exhibit rich and uniform mesoporous structures, and abundant nucleophilic halide ions and hydrogen bond donors are successfully integrated into the HIPs skeleton. The prepared catalysts show the superior CO 2 selective adsorption performance. In addition, the optimal catalyst HIP-IByBA(1:2) exhibits an excellent catalytic activity for the CO 2 cycloaddition without the metals, cocatalysts and solvents. Especially, under the mild condition (70 °C, 1.0 MPa), the catalyst HIP-IByBA(1:2) also maintains a satisfactory catalytic performance, effectively capturing dilute CO 2 (85 %N 2 /15 %CO 2 ) and converting it into cyclic carbonates. The excellent catalytic activity as well as good recyclability and substrate universality makes prepared pyridine-based HIPs promising heterogeneous catalysts for CO 2 cycloaddition reactions.
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GREEN CHEMISTRY
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2025
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IF 9.2
Haiyue Wang,Lili Deng,Bing Fang,Xiaolong Li,Liying Guo,Rongrong Zheng
With spent lithium batteries piling up, the green and high-value utilisation of spent lithium-ion batteries (s-LIBs) becomes increasingly crucial. To address this issue, it is essential to prepare high-value copolycarbonates using s-LIBs. In this study, a range of copolycarbonates of isosorbide (ISB), bisphenol A (BPA), and s-LIBs were synthesised using 1,3-(p-toluic acid zinc salt)Im ZnCl3 as a catalyst. In this way, high molecular weight copolycarbonates (PIBs) (Mw = 57 000–110 000 g mol−1) were obtained. By introducing thermally stable and flexible ISB units, the thermal stability of copolycarbonates was enhanced, and the flexibility of polymer chains was improved. This study showcased the potential for developing environment-friendly soft polycarbonates that can overcome the inherent brittleness of BPA polycarbonates.
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