BIORESOURCE TECHNOLOGY
·
2016
·
IF 4.917
Danlian Huang,Xingmeng Qin,Piao Xu,Guangming Zeng,Zhiwei Peng,Rongzhong Wang,Jia Wan,Xiaomin Gong,Wenjing Xue
A composting study was performed to investigate the degradation of 4-nonylphenol (4-NP) in river sediment by inoculating Phanerochaete chrysosporium ( Pc ). Pc was inoculated into composting Reactor A, C and D, while Reactor B without inocula was used as control. The results showed that composting with Pc accelerated the degradation of 4-NP, increased the catalase and polyphenol oxidase enzyme activities in contaminated sediment. The dissipation half-life (t 1/2 ) of 4-NP in Reactor A, C and D with inocula of Pc were 2.079, 2.558, 2.424 days, while in Reactor B without inocula of Pc it was 3.239 days, respectively. Correlation analysis showed that the contents of 4-NP in sediment in Reactor A and D were negatively correlated with the actives of laccase, whereas no obvious correlation was observed in Reactor B and C. All these findings also indicated that Pc enhanced the maturity of compost, and the best composting C/N ratio was 25.46:1.
研究领域:
环境科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2019
·Vol. 9
·期 4
·513
·
IF 4.034
Jian Hu,Hao Dai,Yanbo Zeng,Yiwen Yang,Hailong Wang,Xudong Zhu,Lei Li,Guobao Zhou,Ruoyu Chen,Longhua Guo
In this study, we report a cross-linker-based poly(ionic liquid) (PIL) for the sensitive detection of 4-nonylphenol (4-NP). PIL was poly(1,4-butanediyl-3,3′-bis-l-vinylimidazolium dibromide) (poly([V2C4(mim)2]Br2)). Poly([V2C4(mim)2]Br2) was prepared via one-step free-radical polymerization. The poly([V2C4(mim)2]Br2) was characterized by infrared spectroscopy, Raman spectroscopy, thermal gravimetric analyzer and scanning electron microscope. The poly([V2C4(mim)2]Br2) was then drop-cast onto a glassy carbon electrode (GCE) to obtain poly([V2C4(mim)2]Br2)/GCE. In comparison with a bare GCE, poly([V2C4(mim)2]Br2)/GCE exhibited higher peak current responses for [Fe(CN)6]3−/4−, lower charge transfer resistance, and larger effective surface area. While comparing the peak current responses, we found the peak current response for 4-NP using poly([V2C4(mim)2]Br2)/GCE to be 3.6 times higher than a traditional cross-linker ethylene glycol dimethacrylate (EGDMA) based poly(EGDMA) modified GCE. The peak current of poly([V2C4(mim)2]Br2) sensor was linear to 4-NP concentration from 0.05 to 5 μM. The detection limit of 4-NP was obtained as 0.01 μM (S/N = 3). The new PIL based electrochemical sensor also exhibited excellent selectivity, stability, and reusability. Furthermore, the poly([V2C4(mim)2]Br2)/GCE demonstrated good 4-NP detection in environmental water samples.Keywords:poly(ionic liquid);cross-linker;electrochemical detection;4-nonylphenol
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL RESEARCH
·
2023
·
IF 8.3
Jian Zhang,Yanbo Zeng,Lifen Chen,Xiaoling Lei,Yiwen Yang,Zhidong Chen,Longhua Guo,Lei Li
A novel core-shell composite of PCN-222 and molecularly imprinted poly (ionic liquid) (PCN-222@MIPIL) with high conductivity and selectivity was prepared for electrochemical sensing 4-nonylphenol (4-NP). The electrical conductivities of some MOFs including PCN-222, ZIF-8, NH 2 -UIO-66, ZIF-67, and HKUST-1 were explored. The results indicated that PCN-222 had the highest conductivity and was then used as a novel imprinted support. PCN-222@MIPIL with core-shell and porous structure was synthesized using PCN-222 as support and 4-NP as template. The average pore volume of PCN-222@MIPIL was 0.085 m 3 g -1 . In addition, the average pore width of PCN-222@MIPIL was from 1.1 to 2.7 nm. The electrochemical response for PCN-222@MIPIL sensor for 4-NP was 2.54, 2.14, and 4.24 times that of non-molecularly imprinted poly (ionic liquid) (PCN-222@NIPIL), PCN-222, and MIPIL sensors, respectively, which result from superior conductivity and imprinted recognition sites of PCN-222@MIPIL. The current response of PCN-222@MIPIL sensor to 4-NP concentration from 1 × 10 −4 to 10 μM presented an excellent linear relationship. The detection limit of 4-NP was 0.03 nM. The synergistic effect between the PCN-222 supporter with high conductivity, specific surface area and shell layer of surface MIPIL results in the outstanding performance of PCN-222@MIPIL. PCN-222@MIPIL sensor was adopted for detecting 4-NP in real samples and presented to be a reliable approach for determining 4-NP.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2017
·
IF 4.9
Panpan Diao,Qi Chen,Rui Wang,Dong Sun,Zhuoping Cai,Hao Wu,Shunshan Duan
Abtsract Three phenolic endocrine-disrupting compounds, 4-nonylphenol, 4-tert-octylphenol and bisphenol A, were determined in water, sediment and biota (fish, shrimp and mollusk) collected from sites along the Pearl River Estuary, China. The 4-nonylphenol, 4-tert-octylphenol and bisphenol A concentrations ranged from 1.20–3352.86 ng/L in the water, < 0.17–20.80 ng/g dw in the sediment and < 1.49–237.12 ng/g dw in the biota. The concentrations of 4-nonylphenol were higher than those of 4-tert-octylphenol and bisphenol A in the water, sediment and organisms. Moreover, the bioconcentration factors (BCFs) and biota-sediment accumulation factors (BSAFs) of 4-nonylphenol and bisphenol A were calculated, and were found to be higher for 4-nonylphenol and in demersal organisms. To assess co-exposure to phenolic endocrine-disrupting compounds, the 4-nonylphenol equivalent was employed to evaluate the potential risks to aquatic organisms and human health, and the results indicated a low risk.
研究领域:
环境科学
·
生态毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FISH & SHELLFISH IMMUNOLOGY
·
2023
·
IF 4.7
Pei-Hua Zheng,Yao-Peng Lu,Xiu-Xia Zhang,Ke-Er Luan,Ze-Long Zhang,Jia-Jun Li,Tong Xu,Jun-Tao Li,Jian-An Xian,Hui Guo,An-Li Wang
4-Nonylphenol (4-NP) is one of the common endocrine-disrupting chemicals (EDCs) in estuaries and coastal zones, which can exert detrimental effects on the physiological function of aquatic organisms . However, the molecular response triggered by 4-NP remains largely unknown in Pacific white shrimp ( Litopenaeus vannamei ). In this study, transcriptomic analysis was performed to investigate the underlying mechanisms of 4-NP toxicity in the hepatopancreas of L. vannamei . Nine RNA-Seq libraries were generated from L. vannamei at 0 h, 24 h, and 48 h following exposure to 4-NP. Compared with 0 h vs 24 h, 962 up- and 463 down-regulated differentially expressed genes (DEGs) were identified, indicating that many genes in L. vannamei were induced to resist adverse circumstances by 4-NP exposure. In contrast, 902 up- and 1027 down-regulated DEGs were revealed in the comparison of 0 h vs 48 h, demonstrating that prolonged exposure to the stress from 4-NP resulted in more inhibited genes. To validate the accuracy of the transcriptome data, eight DEGs were selected for quantitative real-time polymerase chain reaction (qRT-PCR), which were consistent with the RNA-Seq results. Through KEGG pathway enrichment analysis, three specific pathways related to hormonal effects and endocrine function of L. vannamei were enriched significantly, including tyrosine metabolism, insect hormone biosynthesis , and melanogenesis . After 4-NP stress, genes involved in tyrosine metabolism (Tyr) and melanogenesis pathway (AC, CBP , Wnt, Frizzled, Tcf, and Ras) were induced to promote melanin pigment to help shrimp resist adverse environments. In the insect hormone biosynthesis, ALDH , CYP15A1, CYP15A1/C1, and JHE genes were activated to synthesize juvenile hormone (JH), while Spook, Phm, Sad, and CYP18A1 were induced to generate molting hormone. There is an enhanced interaction between the molting hormone and JH, with JH playing a dominant role and maintaining its “classic status quo action”. Our study demonstrated that 4-NP exposure led to impairments of biological functions in L. vannamei hepatopancreas. The genes and pathways identified provide novel insights into the molecular mechanisms underlying 4-NP toxicity effects in prawns and enrich the information on the toxicity mechanism of crustaceans in response to EDCs exposure.
研究领域:
环境科学
·
分子生物学
·
水产养殖学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2010
·
IF 3.083
Jiadong Huang,Xiuming Zhang,Su Liu,Qing Lin,Xiaorui He,Xianrong Xing,Wenjing Lian,Di Tang
4-Nonylphenol (4-NP) was reported to affect the health of wildlife and humans through altering endocrine function. A novel electrochemical sensor for sensitive and fast determination of 4-NP was developed. Titanium oxide (TiO 2 ) nanoparticles and gold nanoparticles (AuNPs) were introduced for the enhancement of electron conduction and sensitivity. 4-NP-imprinted functionalized AuNPs composites with specific binding sites for 4-NP was modified on electrode. The resulting electrodes were characterized by cyclic voltammetry (CV). Rebinding experiments were carried out to determine the specific binding capacity and selective recognition. The linear range was over the range from 4.80 × 10 −4 to 9.50 × 10 −7 mol L −1 , with the detection limit of 3.20 × 10 −7 mol L −1 ( S / N = 3). The sensor was successfully employed to detect 4-NP in real samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
TALANTA
·
2013
·
IF 3.498
Hong-Jun Chen,Zhao-Hui Zhang,Rong Cai,Xing Chen,Yu-Nan Liu,Wei Rao,Shou-Zhuo Yao
In this work, an imprinted electrochemical sensor based on electrochemical reduced graphene covalently modified carbon electrode was developed for the determination of 4-nonylphenol (NP). An amine-terminated functional graphene oxide was covalently modified onto the electrode surface with diazonium salt reactions to improve the stability and reproducibility of the imprinted sensor. The electrochemical properties of each modified electrodes were investigated with differential pulse voltammetry (DPV). The electrochemical characteristic of the imprinted sensor was also investigated using electrochemical impedance spectroscopy (EIS) in detail. The response currents of the imprinted electrode exhibited a linear relationship toward 4-nonylphenol concentration ranging from 1.0×10 −11 to 1.0×10 −8 g mL −1 with the detection limit of 3.5×10 –12 g mL −1 (S/N=3). The fabricated electrochemical imprinted sensor was successfully applied to the detection of 4-nonylphenol in rain and lake water samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL BIOCHEMISTRY
·
2018
·
IF 2.275
Lufei Zheng,Chao Zhang,Jun Ma,Sihui Hong,Yongxin She,A.M. Abd EI-Aty,Yahui He,Hailong Yu,Haijin Liu,Jing Wang
Herein, an imprinted electrochemical sensor based on graphene-Au nanoparticles incorporated with molecularly imprinted polymer (MIP) was fabricated for determination of 4-nonylphenol (4-NP). Grafted MIP electropolymerized on nanoscale multilayer films electrode was achieved using 4-NP as a template and P-aminothiophenol as a functional monomer . The electrochemical properties of the MIP nanoscale multilayer membrances were characterized and measured by cyclic voltammetry and differential pulse voltammetry techniques; using ferrocyanide/ferricyanide-redox marker. Several important parameters were optimized and investigated to improve the performance of the sensor. Under the optimized conditions, the developed sensor showed an excellent linear response over the concentration ranges of 50–500 ng mL −1 (4-NP) with a detection limit of 0.01 ng mL −1 (S/N = 3). The developed sensor showed a good selective recognition of 4-NP compared with structural analogue, exhibited a good reproducibility and accuracy with long-term stability. At last, the feasibility of the proposed methodology was successfully applied fordetection of 4-NP in milk and its packaging materials .
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
DOI
高影响因子
CARBON
·
2018
·
IF 7.082
Yuanyuan Zhang,Peng Yan,Qijin Wan,Nianjun Yang
Metal-organic frameworks (MOFs) are attractive materials for electrochemical applications because of their large surface areas and rich pore structures . However, their poor electrical conductivity hinders these applications. In this contribution, the decoration of chromium terephthalate MOFs (MIL-101(Cr) crystals) with reduced graphene oxide (rGO) is proposed to improve the electrical conductivity of MIL-101(Cr) crystals. These nanocomposites (MIL-101(Cr)@rGO) were prepared using a simple chemical reduction method. Their morphology, interfacial properties , and electrochemical applications were investigated using electron microscopy , electrochemical, and related techniques. With an introduction of rGO into MIL-101(Cr) crystals, the conductivity of MIL-101(Cr)@rGO nanocomposites was much improved. As a case study of electrochemical applications of MIL-101(Cr)@rGO nanocomposites, the MIL-101(Cr)@rGO nanocomposite coated electrodes were employed for the voltammetric study of 4-nonylphenol. An irreversible, adsorption-controlled, one electron and one proton involved oxidation process was observed. By use of the recorded anodic peak current as the physical parameter, the sensitive and reproducible monitoring of 4-nonylphenol was realized in the range of 0.1–12.5 μM with a detection limit of 33 nM. The MIL-101(Cr)@rGO nanocomposites are thus useful electrode materials . The proposed strategy provides a simple and efficient approach to expand easily the applications of MOFs into various electrochemical fields.
研究领域:
材料科学
·
环境科学
·
电化学
✓ 已验证
DOI
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2015
·Vol. 17
·期 29
·19401-19409
·
IF 4.493
Feng Quan,Yun Hu,Xingchen Liu,Chaohai Wei
In this study, mesoporous SBA-15 bifunctionalized with cetyl and amino groups (cetyl/amino-SBA-15) was successfully prepared by a post-synthesis grafting method. Detailed characterization by XRD, FT-IR, N2 adsorption–desorption and elemental analysis confirmed that cetyl/amino-SBA-15 still retained a long-range ordered hexagonal mesostructure. Cetyl and aminopropyl groups were simultaneously functionalized on the surface of SBA-15. The adsorption capacity of cetyl/amino-SBA-15 was much higher than the arithmetic sum of those of cetyl-SBA-15 and amino-SBA-15 due to the cooperative effect of hydrogen bonding/electrostatic interaction between 4-nonylphenol (4-NP) and aminopropyl groups and hydrophobic interactions between 4-NP and cetyl groups. The effects of the dosage and mole ratio of cetyl and amino groups on the adsorption properties of cetyl/amino-SBA-15 for 4-NP were also investigated. Cetyl/amino-SBA-15 exhibited excellent adsorption capacity over a wide range of pH values and cetyl/amino-SBA-15(3.2/0.8) displayed the highest adsorption capacity up to 120 mg g−1. Furthermore, cetyl/amino-SBA-15 exhibited high adsorption selectivity for 4-NP against phenol as well as high reusability, showing great potential for applications in wastewater treatment.
研究领域:
环境科学
·
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
·
2020
·Vol. 42
·期 9
·2881-2894
·
IF 3.472
Ding Na,Wang Lu,Kang Yuan,Luo Kesong,Zeng Diya,Man Yu Bon,Zhang Qiuyun,Zeng Lixuan,Luo Jiwen,Jiang Feng
The transcriptomic response of green microalga Chlorella sorokiniana exposure to environmentally relevant concentration of cadmium(II) (Cd) and 4- n -nonylphenol (4- n -NP) was compared in the present study. Cd and 4- n -NP exposure showed a similar pattern of dys-regulated pathways. The photosystem was affected due to suppression of chlorophyll biosynthesis via down-regulation of Mg-protoporphyrin IX chelatase subunit ChlD (CHLD) and divinyl chlorophyllide a 8-vinyl-reductase (DVR) in Cd group and via down-regulation of DVR in 4- n -NP group. Furthermore, the reactive oxygen species (ROS) could be induced through down-regulation of solanesyl diphosphate synthase 1 (SPS1) and homogentisate phytyltransferase (HPT) in Cd group and via down-regulation of HPT in 4- n -NP group. Additionally, Cd and 4- n -NP would both cause the dys-regulation of carbohydrate metabolism and protein synthesis. On the other hand, there are some different responses or detoxification mechanism of C. sorokiniana to 4- n -NP stress compared to Cd exposure. The increased ROS would cause the DNA damage and protein destruction in Cd exposure group. Simultaneously, the RNA transcription was dys-regulated and a series of changes in gene expressions were observed. This included lipid metabolism, protein modification, and DNA repair, which involved in response of C. sorokiniana to Cd stress or detoxification of Cd. For 4- n -NP exposure, no effect on lipid metabolism and DNA repair was observed. The nucleotide metabolism including pyrimidine metabolism and purine metabolism was significantly up-regulated in the 4- n -NP exposure group, but not in the Cd exposure group. In addition, 4- n -NP would induce the ubiquitin-mediated proteolysis and proteasomal degradation to diminish the misfolded protein caused by ROS and down-regulation of heat shocking protein 40. In sum, the Cd and 4- n -NP could cause the same toxicological effects via the common pathways and possess similar detoxification mechanism. They also showed different responses in nucleotide metabolism, lipid metabolism, and DNA repair.
研究领域:
环境毒理学
·
分子生物学
·
微藻研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
·
2020
·
IF 2.897
Jiao Yang,Qingyi Huang,Huan Liu,Xiong Zhou,Zhuoquan Huang,Quansheng Peng,Chunhong Liu
Environmental endocrine disruptors 4-nonylphenol (NP) and 4-tert-octylphenol (OP) may cast huge harm to human health. We used a rat model to observe the influence of NP or/and OP exposure on anxiety-related behaviors and the underlying mechanisms. Eighty male Sprague-Dawley (SD) rats were randomly divided into 10 groups: control group (corn oil), NP groups [30, 90, 270 mg/kg], OP groups [40, 120, 360 mg/kg] and NO groups [(mixed with the corresponding NP, OP alone exposed low, medium and high dose according to the natural environment exists NP:OP = 4:1]. The rats were orally administered every other day for 30 days. The neurobehaviors of rats were evaluated by open-field test (OFT) and elevated plus-maze test (EPM), and the concentrations of 5-HT, monoamine oxidase (MAOA), serotonin transporter (SERT), vesicular monoamine transporter 2 (VAMT2), 5-hydroxytryptamine 1A (5-HT 1A ), 5-hydroxytryptamine 2A (5-HT 2A )，and 5-hydroxytryptamine 2C (5-HT 2C ) in the rat prefrontal cortex were analyzed by ELISA . OFT and EPM tests showed that NP or/and OP exposure induced anxiety-related behaviors in rats. 5-HT levels were significantly increased compared with the control group. The levels of MAOA, SERT, VAMT2, 5-HT 1A , 5-HT 2A, and 5-HT 2C in the prefrontal cortex reduced in different degrees by high-doses NP or/and OP exposure. In summary, NP or/and OP exposure might cause anxiety-related behaviors in rats through regulating neurotransmitter 5-HT levels by altering the expression of 5-HT decomposition enzyme MAOA, transporters SERT and VMAT2, and 5-HT receptors 5-HT 1A , 5-HT 2A, and 5-HT 2C .
研究领域:
毒理学
·
神经科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）