CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Ting Xin,Zeyu Zheng,Zuo Li,Yue Wu,Yang Liu,Binbin Zhou,Jibao Lu,Xiaoliang Zeng,Fan Yang,Gang Li,Rong Sun,Pengli Zhu
Catechol-rich lignin reconstructs native CuO during epoxy curing. • A Cu 2 O-rich interphase integrates Cu O bonding and mechanical locking. • Cu shear strength reaches 21.1 MPa with cohesive fracture. • Adhesion remains robust after 85 °C/85% RH aging and 260 °C heating. • Broad substrate adhesion and void-free underfill filling are demonstrated. Robust epoxy‑copper adhesion is widely required in Cu-based electronic devices, protective coatings, and packaging assemblies, yet it is often limited by mechanically fragile native copper oxides that act as weak boundary layers. Here, we introduce a robust epoxy adhesive that spontaneously forms chemically integrated and mechanically interlocked interphases on copper surfaces during curing. The epoxy adhesive achieves a high Cu adhesion strength of 21.1 MPa and demonstrates application-relevant performance, including adhesion to Si, Al, and steel, packaging-relevant reliability, and underfill processability. The epoxy adhesive incorporates catechol-rich demethylated lignin, whose redox-active motifs reconstruct the native CuO-rich surface into a nanostructured Cu 2 O-rich interphase. This unique interfacial architecture enables simultaneous chemical coordination, elemental interpenetration, and mechanical interlocking, thereby transforming the weak native oxide into a load-bearing functional interphase. This work provides a facile strategy for robust epoxy‑copper adhesion in Cu-based electronic and packaging applications. Download: Download high-res image (139KB) Download: Download full-size image
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CARBOHYDRATE POLYMERS
·
2025
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IF 12.5
Lan Zhao,Fengcai Lin,Haijun Li,Lingling Qian,Yingshan Shi,Zhiyi Cao,Xuan Yang,Biao Huang,Beili Lu,Hanyang Liu,Lirong Tang
Silicon (Si) is a promising anode for high-energy-density batteries, but its ~300 % volume expansion causes particle fracture and electrode instability. Effective binders are essential for maintaining electrode integrity. Inspired by the adhesion mechanism of natural ivy, we developed a small-molecule-enhanced polymer binder derived from phosphorylated cellulose nanocrystals (PCNCs) and acrylic acid rosin to enhance the electrochemical and mechanical performance of Si anodes. PCNCs, with their high aspect ratio and surface activity, construct an interconnected three-dimensional (3D) network within the polymer matrix, reinforcing structural stability. Additionally, phosphate groups promote water-based polymer compatibility and ion transport, facilitating efficient lithium-ion conduction. Acrylic acid rosin mimics the adhesion mechanism of Parthenocissus tricuspidata , establishing strong hydrogen bonds, ion-dipole interactions, and covalent crosslinking with Si particles. This incorporation also forms a unique “soft outside, rigid inside” topology, buffering stress, protecting the solid electrolyte interface (SEI), and synergizing with polyacrylic acid (PAA) to form a robust network. The binder provides an excellent electrochemical performance, achieving a high initial coulombic efficiency (86.85 %), superior ionic conductivity (18.825 mS/cm 2 ), and remarkable cycling stability at high silicon loading (maintaining 1272 mAh/g after 100 cycles at 0.2C). Its green synthesis and scalability offer a sustainable path for next-generation Si anodes.
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Arabian Journal of Chemistry
·
2023
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IF 6
Guangpeng Xu,Bingying Jia,Bang Xu,Shiyang Bai,Jihong Sun,Tallat Munir
Using poly(acrylic acid) (abbreviated as PAA) as a shell, bimodal mesoporous silicas (abbreviated as BMMs) as a core, and bipyridine-proline (abbreviated as Z) as an active species, a facile approach for preparation of the [email protected] nanocomposites with core–shell structure was proposed, which was used as a suitable pH-sensitive catalyst for asymmetric aldol reaction between p-nitrobenzaldehyde and cyclohexanone. Their microstructural features and physicochemical properties were extensively characterized by various methods, such as powder X-ray diffraction patterns, N 2 adsorption–desorption isotherms, the scanning (and transmission) electron microscopy images, the dynamic light scattering measurements, the thermogravimetric analysis, the elemental analysis, and the Fourier transform infrared spectroscopy spectra. Particularly, their fractal evolution, the pair distance distribution function, and the Porod plots were demonstrated via the small-angle X-ray scattering patterns. The results elucidated that the PAA was successfully incorporated onto the external amino-modified surfaces of the mesoporous BMMs, and the particles having PAA grafted thereon had a pH-responsive shell in thickness of around 0.97 nm for controlled release of Z species by adjusting pH value of the reaction medium. Besides, the synthesized [email protected] presented the satisfactory catalytic yields (around 80%) in comparison with the homo- and heterogeneous catalytic system using Z or [email protected] as the catalysts.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2023
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IF 6.2
Ya-Nan Zhao,Kai-Sheng Yao,Ao-Zhou Wang,Wei-Wei Lu
Developing a facile green strategy to one-step prepare anisotropic bimetallic nanomaterials with hierarchical structures is preferred choice but remains technically challenge. Here, a simple ionic liquid-directed route is developed for the fabrication of Pd 3 Cu 1 alloy nano-urchins (NUs) at room temperature in aqueous solution. To achieve the synthetic protocol, water-soluble Na 2 PdCl 4 and CuCl 2 are used as the initial raw materials, ascorbic acid as the reducing agent, and a common ionic liquid 1-butyl-3-methylimidazolium chloride ([C 4 mim]Cl) is applied to guide the growth and formation of Pd 3 Cu 1 NUs, vividly demonstrating the green and cost-saving features. The various factors affecting the shapes and sizes of products are researched. The results show that [C 4 mim]Cl is vital to the formation of thorny Pd 3 Cu 1 NUs. The Pd 3 Cu 1 NUs possess uniform morphology, lots of sharp thorns, high specific surface area and 3D freestanding structures, and exhibit outstanding catalytic activity, selectivity and durability for p -nitrobenzaldehyde hydrogenation having 100% conversion and 94.6% selectivity to p -aminobenzaldehyde. It is believed that the 3D Pd 3 Cu 1 NUs would also have hopeful prospects in electrocatalysis , sensor and beyond.
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Catalysis Science & Technology
·
2022
·Vol. 13
·期 3
·684-693
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IF 6.177
Lian Xu,Dan Nie,Bing-Mei Su,Xin-Qi Xu,Juan Lin
The synthesis of chloramphenicol, a kind of amphenicol antibiotic with broad-spectrum antibacterial activity, is challenging due to its stereochemistry. Here, we have designed a four-step chemoenzymatic strategy, including a biocatalytic step mediated by L-threonine transaldolase from Pseudomonas sp. (PsLTTA) to convert 4-nitrobenzaldehyde (1) to (2S,3R)-2-amino-3-hydroxy-3-(4-nitrophenyl)propanoic acid (2) followed by a three-step chemical reaction to obtain chloramphenicol. A rational design of PsLTTA was devised by reshaping the substrate binding pocket and substrate access channel, resulting in the best variant PsLTTA-N35A/C57I/F59A/H69F (PsLTTA-Mu9), which achieved a 7.1-fold higher yield of 2 than wild-type PsLTTA. After coupling with ScADH/CbFDH to remove the byproduct acetaldehyde and optimizing the reaction conditions, the whole-cell catalyst BL21(PsLTTA-Mu9/ScADH/CbFDH) could synthesize 200 mM of 2 in four hours with 99% conversion and 97.7% de, delivering the highest time–space yield (11.3 g L−1 h−1) ever reported. Finally, the chemoenzymatic approach was applied for the gram-scale synthesis of 5 with a high overall yield (54%). The success of this strategy demonstrates the great advantage of the chemoenzymatic approach in the asymmetric synthesis of chloramphenicol and may contribute to its industrial synthesis.
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BIOORGANIC CHEMISTRY
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2022
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IF 5.307
Shuang-Qiang Liu,Zhi-Chen Mao,Yan-Li Xu,Xiao-Man Chen,Hui-Ling Wang,Qi Wang,Jian-Hua Wei,Ri-Zhen Huang,Ye Zhang
Two biotin-polyethylene glycol (PEG)4‑diarylidenyl piperidone (DAP) prodrugs, compounds 3a and 3b , were designed as antineoplastic agents and synthesized by coupling biotin to bifluoro- and binitro-substituted DAP derivatives ( DAP-F and DAP-NO 2 ) through a PEG4 linker, respectively. The results of the MTT (3-(4, 5)-dimethylthiahiazo (-z-y1)-3, 5-di- phenytetrazoliumromide) assay and a SW480 xenograft model identified compounds 3a and 3b as candidate antitumor agents with good efficacy, limited toxicity, and low resistance, as compared to the original drugs ( DAP-F and DAP-NO 2 ), cisplatin, and doxorubicin (dox). The results of a preliminary pharmacokinetic study showed that compounds 3a and 3b slowly released their original drug DAP-F and DAP-NO 2 within 12 h after intraperitoneal injection, respectively. Western blot analysis and computer docking simulations indicated that DAP-F , DAP-NO 2 , and compounds 3a and 3b were indeed inhibitors of signal transducer and activator of transcription 3 (STAT3) and the antitumor effects of compounds 3a and 3b were exerted by sequentially interacting with the SH2-binding domain followed by the DNA-binding domain after releasing the original drugs DAP-F and DAP-NO 2 , respectively. These results suggest that the targeted prodrug model led to good antitumor efficacy with reduced toxicity, while a dual STAT3-binding model may promote antitumor efficacy and resistance.
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JOURNAL OF CHROMATOGRAPHY A
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2022
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IF 4.601
Xuejiao Xu,Lijin Huang,Qin Shuai
The ubiquitous occurrence of nonsteroidal anti-inflammatory drugs (NSAIDs) in the environmental water system has drawn significant concerns due to their adverse effects. The accurate monitoring the content of them is of great significance but challenging in terms of the complex matrix and trace concentration. In this work, a porphyrin-based magnetic porous organic polymer composite (PM-POP) was prepared through a solvent-free synthetic method. Owing to the highly porous structure and strong affinities, the as-prepared PM-POP could be utilized as a highly efficient adsorbent for the magnetic solid phase extraction (MSPE) of NSAIDs. Combining with the high-performance liquid chromatography separation with ultraviolet detector (HPLC-UV), a sensitive analytical method was established, which exhibited wide linear ranges (0.1–400 μg/L) and large enrichment factors (EFs) (39.5–82.9 folds) along with good precision (intra-day RSD ≤ 4.9%) and repeatability (inter-day RSD ≤ 8.4%). Ultimately, it was applied to determinate trace NSAIDs in practical water samples successfully, demonstrating its good application prospect in environmental analysis.
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CHEMICAL ENGINEERING JOURNAL
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2023
·
IF 15.1
Fengliang Cao,Qingshan Zhao,Debin Kong,Xiaojie Tan,Xinxin Li,Tengfei Liu,Linjie Zhi,Mingbo Wu
Atomically dispersed metal-nitrogen-carbon (M-N-C) catalysts show great potential for heterogeneous catalysis. However, recognizing and engineering the microenvironment of M-N x sites to achieve satisfactory catalytic performance remains challenging. Herein, we propose a facile g-C 3 N 4 -assisted template strategy to anchor atomic Fe-N 4 sites on highly nitrogen-doped carbon nanosheets. Through regulating the ratio and type of peripheral nitrogen species by carbonization temperature, the optimal Fe-N-C-800 catalyst showed significantly boosted catalytic activities (overall turnover frequency of 13.43 min −1 and activation energy of 19.44 kJ mol −1 ) for nitroarene reduction with extremely low reductant dosage, exceeding most reported metal catalysts. Experimental and theoretical results reveal appropriate graphitic- and pyrrolic-N dopants surrounding the Fe-N 4 center can tailor the local electronic structure and contribute to obvious upshift of the d-band center, which dramatically promotes the adsorption and conversion of reactant substrates, eventually delivering the unprecedented catalytic performance. This work provides a guide for rational coordination environment regulation of single-atom catalysts for efficient chemical transformations.
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INORGANIC CHEMISTRY COMMUNICATIONS
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2023
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IF 3.8
Feiyan Wang,Linhong Liao,Xiaohui Liu,Jie Zhang,Fengshou Wu
Glucose is regarded as a clinical biomarker, and the abnormal level of glucose in blood would cause endocrine metabolic diseases. Thus, it is of great significance to develop a simple, accurate, and sensitive method for glucose detection. In this work, we synthesized an iron porphyrin-based porous organic framework (Fe-POF) through a facile alkylation reaction between 5,10,15,20-tetra(4-aminophenyl) porphyrin (TAPP) and cyanuric chloride. Fe-POF exhibited excellent peroxidase-like activity and could be used to detect hydrogen peroxide and the molecules associated with hydrogen peroxide such as glucose. The structure of Fe-POF was confirmed through a series of methods, such as FT-IR, SEM, EDS, TEM, and XPS. Fe-POF exhibited excellent peroxidase-like activity, which could catalyze the oxidization of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) into blue product (ox-TMB) in the presence of hydrogen peroxide (H 2 O 2 ). Based on this phenomenon, a simple colorimetric assay was constructed for the detection of H 2 O 2 and glucose with high selectivity and sensitivity. The detection limit of H 2 O 2 and glucose was calculated to be 1.8 and 1.39 μM, respectively. Finally, Fe-POF was applied as a colorimetric sensor for rapid detection of glucose in diluted serum samples.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Zhiyi Huang,Huan Wang,Jiahao Du,Xiaochun Liu,Guoyi Pan,Xingshan Yin,Wenjing Lin,Xiaofeng Lin,Yingjuan Sun,Guobin Yi,Li Niu
The preparation of lignin-based polyurethanes with excellent mechanical properties and recyclability remains extremely challenging because of the poor compatibility of lignin and matrix. Inspired by the multiple structures of spider silk and pearl layers, high-strength, heat-resistant and recyclable lignin-based polyurethanes (LPUs) were prepared by introducing weak hydrogen bonds, strong hydrogen bonds and dynamic silyl ether covalent bonds. Multiple hydrogen bonds provided a large energy dissipation mechanism. The covalent linkage between lignin and matrix promoted their compatibility and formed a robust cross-linking network. Depending on the multi-level dynamic interactions, the prepared elastomer exhibited a mechanical strength of 73 MPa, which was 1.9 times higher than that of the blank sample, with an initial thermal decomposition temperature of 310.5 °C and a good recyclability. Especially, the mechanical strength of LPUs was up to 99 MPa after mechanical training. In addition, the abundant conjugated structure of lignin endowed LPUs with an excellent photothermal conversion ability. Under the irradiation of NIR light with 4000 w m −2 , the surface temperature increased to 95 °C within two minutes, exhibiting a stable photothermal performance even after 6 cycles. This work showed the application prospects of LPUs in the fields of high strength engineering materials and photo-induced actuators.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Xiaoqing Yuan,Ju Liu,Yanlei Wang,Xingming Jie,Jingyu Qin,Hongyan He
Knoevenagel condensation reaction is important for generating C C double bonds and providing various valuable intermediates in organic chemistry, which always need harsh conditions including high reaction temperature, difficult catalyst recovery, difficult product separation, etc. In this work, a novel class of dual-responsive emulsion reactor was prepared for the Knoevenagel condensation reaction between malononitrile and aromatic aldehyde, where the temperature and CO 2 -responsive ionic liquids (ILs) were used as an emulsifier, responder, and catalyst simultaneously. Driven by temperature or CO 2 , the emulsion reactor undergoes reversible and controllable transformations between emulsification and demulsification, where efficient catalytic reactions, product separation, and reactor recovery are all achieved. The isolated product yield of 2-(4-chlorobenzylidene)-malononitrile remained above 90% after 5 cycles of the emulsion reactor. NMR and molecular dynamics simulations showed that the temperature drives the reversible stretching and curling of the polyether chain on the cation, while CO 2 reacts with the –COO - group on the anion to form carbonates and carboxylic acids in water, leading to changes in the surface activity of ILs, thereby reversibly regulating the demulsification and emulsification of the emulsion. Hence, through the dual stimuli-responsive ILs, the efficient reaction can be performed in the homogeneous phase, and the products and catalysts can be easily separated in the heterogeneous phase. These results on the revisable microreactor can not only help to design the smart and efficient “homogeneous reaction-heterogeneous separation” systems but also support the development of green sustainable chemistry.
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JOURNAL OF HAZARDOUS MATERIALS
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2022
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IF 14.224
Menglan Gao,Xiaobin Liao,Jing Yu,Xinna Lin,Huan Qi,Linlu Shen,Shupo Liu,Zhimin Yang
Bromide ions (Br - ) affected non-brominated nitroso-dimethylamine (NDMA) formation during ozonation , but the mechanism is still unclear. 1,1,1′,1′-tetramethyl-4,4′-(methylene-di- p -phenylene) di-semicarbazide (TMDS) was chosen to further probe this problem. The results indicated that low levels of Br - (≤20 μM) enhanced NDMA from 3.27 to 7.56 μg/L, while its amount slightly dropped to 6.22 μg/L raising Br - to 100 μM. It was experimentally verified that intermediates 1,1-dimethylsemicarbazide (DMSC) and 1,1-dimethylhydrazine (UDMH) played important roles on promoting NDMA generation, whose contribution rates were 40.2% and 32.2%, respectively. The brominated substances with higher NDMA molar yields were detected. ∙OH reduced NDMA formation without Br - , while it played promotion role with Br - ; the corresponding contribution rates were − 26.9% and 29.2%, respectively. No matter with or without Br - , both ∙O 2 - and l O 2 brought a boost to NDMA formation, their contribution ratios were 34.9% and 58.1% without Br - , while raised significantly to 64.6% and 81.5% when Br - existed. Br - not only facilitated NDMA formation, but also benefited the degradation of TMDS. Based on the calculation results and intermediates detected, the influence mechanisms of Br - were proposed. The results would provide theoretical basis and technical guarantee for treating NDMA precursors and bromide co-existing water in the future.
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