Scientific Reports
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2021
·Vol. 11
·期 1
·1-10
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IF 4.38
Ma Yinzheng,Wang Yuanxiao,Zhou Xia,Yang Heng,Zhang Huixin,Chen Wenhan,Zhang Haiying,Zhang Yunxia,He Xiaowen
Clausena lansium (Lour.) Skeels seeds have been shown to have diverse beneficial medical value due to their unique active components. This study analysed the composition of essential oils (EOs) of C. lansium seeds and investigated their potential antifungal effects against Candida strains . A total of forty-six components were identified in all samples by gas chromatography-mass spectrometry (GC–MS). The main components were sabinene, β -phellandrene and 4-terpineol. Thirteen EOs of C. lansium seeds were classified into three clusters based on their components. Cluster analysis showed that the difference between the tropics and subtropics was the greatest. These EOs and the three main chemicals showed different antifungal activities against five Candida species ( C. albicans , C. tropicalis , C. glabrata , C. krusei and C. parapsilosis ). The antifungal activity against C. glabrata and C. krusei was higher than that against other Candida strains. EOs of C. lansium seeds displayed noteworthy antifungal activity against both sensitive and fluconazole-resistant strains, with inhibition zone diameters in the range of 9.4–23.4 mm. Comprehensive analysis illustrated the importance of sabinene, β -phellandrene and 4-terpineol to antifungal activity, and there may be some synergistic effects with other components. These results represent the first report about the correlation between the chemical composition of EOs of C. lansium seeds and antifungal activity. Taken together, the results obtained provide scientific evidence for the traditional use of C. lansium seeds waste.
研究领域:
植物化学
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微生物学
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药理学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Chuanxiang Cheng,Yujie Lei,Tiantian Min,Yushan Zhang,Jin Yue
4-Terpineol (4-TA), a typical monocyclic monoterpene essential oil compound with important biological activities, poor stability and solubility severely hamper its biological activities. To date, β-cyclodextrin (β-CD) encapsulating essential oil to form inclusion complexes (ICs) is considered as a satisfactory treatment. Nevertheless, the detailed inclusion mechanism of β-CD for 4-TA especially the behavior of 4-TA during inclusion formation have not available yet. Herein, 4-TA/β-CD ICs were successfully synthesized by the co-precipitation method, and hydrogen bonds and hydrophobic interactions played a key role in the formation of ICs, and the isopropyl of 4-TA entered the cavity through the wide rim of β-CD. Moreover, the release profile demonstrated that high RH (85 % and 99 %) triggered the release of TA from ICs. This study suggests the great potential of cyclodextrin inclusion strategy for improving the stability and sustained release of 4-TA in food preservation application.
研究领域:
食品科学
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化学
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DOI
PubMed
高影响因子
JOURNAL OF FOOD SCIENCE
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2022
·Vol. 87
·期 10
·4609-4621
·
IF 3.693
Chuan Cao,Changyue Deng,Jinwei Hu,Yibin Zhou
In the present study, the formation and structure of the inclusion compound of large-ring cyclodextrin and 4-terpineol were obtained through different experiments and molecular dynamics (MD) simulation. The analysis of FTIR, 1 H-NMR, and thermodynamic results confirmed the formation of clathrates. Analysis of molecular structure (root-mean-square deviation and radius of gyration), solubility, and interaction energy (Coul, H bond) based on MD simulations further clarified the nature of the clathrate and the conformational changes caused by guest molecules as well as inclusion complexes process trends. The inclusion complex reportedly has a new crystal structure with improved thermal stability. Practical Application This is the first work to demonstrate the complex formation between 4-terpineol and large-ring cyclodextrin by molecular dynamics simulation. Molecular dynamics simulation confirmed the formation of inclusion complexes theoretically. Conformational changes of the molecules and the formation of complexes with improved thermal stability were observed. Complexing with large-ring cyclodextrin can be used as an effective means to encapsulate the aroma/flavor compounds.
研究领域:
食品科学
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化学
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DOI
PubMed
高影响因子
Food and Bioprocess Technology
·
2026
·Vol. 19
·期 7
·351
·
IF 5.6
Sheng Jie,Song Shuxuan,Wang Wenbo,Zhang Jialong,Wang Jiaxin,Chen Ziyi,Sun Maoquan,Huang Honghua,Song Yishan
This study utilised microfibrillated cellulose (MFC) and acetylated starch (AS) as structural frameworks, with 4- terpineol (4-TA) serving as the antimicrobial agent. A multifunctional biodegradable aerogel with water absorption, antibacterial, cushioning and slow-release properties has been developed as a freshness-preserving pad for fruit and vegetables. The system analysed the effects of different mass ratios of MFC/AS on the density, porosity, mechanical properties, water absorption rate, and oil absorption rate of aerogels. Additionally, the release characteristics, antibacterial properties, and biodegradability of the aerogel were investigated. The results indicate that, the aerogel with a MFC/AS mass ratio of 1:3 has the best comprehensive performance, exhibiting a compressive strength of 0.030 ± 0.002 MPa and an springiness of 0.577 ± 0.031. It also exhibits exceptional water and oil absorption capacities, reaching 1549.40 ± 38.29% and 3887.33 ± 86.56%, respectively. Moreover, it also exhibits fine sustained-release properties, antibacterial performance and biodegradability. Following 240 h of release, more than 50% of 4-TA remained encapsulated within the aerogel. The inhibition zone diameters against Escherichia coli and Staphylococcus aureus were 30.37 ± 1.25 mm and 32.25 ± 1.04 mm, respectively. The application of aerogel to strawberry preservation extends their shelf life from 1 to 3 days, outperforming commercially available preservation pads. Therefore, this study offers a novel approach for the development of fruit and vegetable preservation pads. Graphical
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DOI
高影响因子
FOOD HYDROCOLLOIDS
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2024
·
IF 11
Chuanxiang Cheng,Xiaoyun Ma,Tiantian Min,Yuwan Luo,Yujie Lei,Ting Zhao,Jin Yue
Antibacterial active packaging enables extensive biological effects to improve food safety. However, it still remains difficult to achieve controlled and precise release of bioactive compounds to the specific target location with required quantity in food packaging applications. Here, a novel relative humidity (RH) - responsive polyvinyl alcohol/chitosan (PVA/CS) composite nanofibrous film incorporated with 4-terpineol/β-cyclodextrin inclusion complexes (4-TA@β-CD ICs) was engineered by electrospinning that can be exploited as a functional packaging materials. The characterization results showed the thermal stability of the films was enhanced after the incorporation due to the hydrogen bonds between ICs and biopolymers. Besides, the 4 wt% 4-TA@β-CD ICs/PVA/CS film exhibited optimized morphology, crystallinity, mechanical properties, and water vapor permeability. The incorporation of ICs dramatically promoted the antioxidant and inhibition activity of the film especially towards Shewanella putrefaciens . Moreover, the release behavior of 4-TA indicated that high RH accelerated the releasing rate, and the film obtained a sustained-release effect. Finally, the film with long-term antibacterial effectiveness succeeded in extending the shelf life of Litopenaeus vannamei shrimps by an additional 2 days at 4°C. This work developed a RH-responsive release packaging material, which may serve as an effective active food packaging.
研究领域:
材料科学
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食品科学
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纳米技术
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生物技术
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DOI
高影响因子
Insects
·
2022
·Vol. 13
·期 12
·1126
·
IF 3.139
Xing Huang,Linjie Du,Tiantian Liu,Rui Ma,Xing Liu,Haibin Yuan,Shuai Liu
Simple SummaryPlutella xylostella(L.) (Lepidoptera: Plutellidae) is the most destructive pest of cruciferous crops around the world. The inappropriate use of insecticides to manage it has brought the development of resistance to several pesticide active ingredients. Keeping in view the resistance problem and long-term application, essential oils of plants may provide an environment-friendly solution to manage pests. Although the essential oil ofArtemisia lavandulaefoliaDC. was proven to exhibit promising insecticidal activities againstP. xylostella, which components have insecticidal activities are unknown. In the present study, four bioactive components were identified fromA. lavandulaefoliaessential oil by GC/MS, and their insecticidal activities againstP. xylostellawere also evaluated. Among them, (-)-4-terpineol was proven to be mostly responsible for its insecticidal activity againstP. xylostella. This effect was associated with decreased activity of GST, CAT, AChE and Na+/K+-ATPase. Overall, our findings indicated that (-)-4-terpineol may offer an alternative source for the control ofP. xylostella.AbstractPlutella xylostella(L.) is one of the most serious pests of cruciferous vegetables. Our previous work demonstrated that the essential oil ofArtemisia lavandulaefoliaDC. exhibits promising insecticidal activities againstP. xylostella. This study further characterizes the key components that are responsible for the insecticidal effect. In total, 47 compounds (96.52% of the total compounds) were identified from the total oil using GC-MS, and the major compounds were eucalyptol (21.57%), D(+)-camphor (17.33%), (-)-4-terpineol (9.96%) and caryophyllene oxide (10.96%). Among them, (-)-4-terpineol showed significantly larvicidal and fumigant activities againstP. xylostella. The LD50of (-)-4-terpineol was 43.15 mg/mL at 12 h and 31.22 mg/mL at 24 h for 3rd instar larvae, and the LC50for adults was 8.34 mg/mL at 12 h and 7.35 mg/mL at 24 h. In addition, the adults treated with (-)-4-terpineol showed varying degrees of inhibitory activity toward glutathione S-transferase, catalase, acetylcholinesterase and Na+/K+-ATPase at different post-treatment intervals and concentrations. The results indicate that (-)-4-terpineol has promising insecticidal activities againstP. xylostella, and it has good inhibitory effects on the four enzymes ofP. xylostellaadults.Keywords:Plutella xylostella;bioactive compounds;(-)-4-terpineol;insecticidal activities
研究领域:
植物学
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昆虫学
·
农业科学
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产品关联
DOI
PubMed
高影响因子
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