JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2022
·
IF 5.141
Chunyue Zhao,Jinfeng Xing
In this study, a new method of photopolymerization with the dynamic exposure was developed to solve the issue of uneven laser-induced polymerization and prepare nanogels with uniform size. Dynamic exposure was used to divide the photopolymerization process into illumination period and dark period. In illumination period, free radicals were generated to induce polymerization. In the dark period, the incompletely cross-linked nanogels and oligomers were redistributed to homogenize the polymerization system. The double bond conversion of the polymerization in the dynamic exposure mode was equal to that in the conventional exposure mode. The simple dynamic exposure mode optimized the process for preparing the nanogels by laser-induced photopolymerization.
研究领域:
材料科学
·
高分子化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2020
·
IF 7.489
Xiaoying Wang,Yuanyuan Peng,Jhair Peña,Jinfeng Xing
Nanogels have been widely prepared and characterized in recent years due to their unique advantages. Here, an effective, original, and facile method of emulsion-free photopolymerization at 532 nm without surfactant was developed to prepare nanogels based on poly(ethylene glycol) diacrylate (PEGDA). The 532 nm continuous laser with symmetrical energy distribution like a three-dimensional shape of a straw hat was used to control the reaction region. The self-emulsification of PEGDA in water was studied and PEGDA micelles were directly cross-linked by controlling the laser energy. The number of micelles participating in the microreaction region and the double bond crosslinking between micellar aggregates and inside micelles were reasonably regulated. The size of the nanogels could be effectively modulated by controlling reaction parameters including laser power, monomer concentration, initiator concentration, and reaction time. Finally, ultrasmall nanogels with around 30 nm in size were prepared by balancing double bond crosslinking between micellar aggregates and inside micelles.
研究领域:
材料科学
·
纳米技术
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2023
·
IF 4.3
Siyuan Yu,Siyu Lu,Jinfeng Xing
Nanogels with a unique three-dimensional structure have wide applications in tissue engineering and drug delivery. In this study, polyethylene glycol diacrylate (PEGDA) nanogels were prepared by photopolymerization under the irradiation of 532 nm laser using a mixture of ethanol and water as the solvent. The reaction parameters including laser power and stirring speed were systematically investigated. Since the amphiphilic PEGDA self-emulsifies to form micelles in water, the regulation of ethanol content in reaction medium can tune the size and morphology of nanogels. Based on these, the photopolymerization mechanism of PEGDA in aqueous solution of ethanol was proposed.
研究领域:
材料科学
·
纳米技术
·
高分子化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2021
·
IF 4.291
Junjie Li,Yuanyuan Peng,Jhair Peña,Jinfeng Xing
Nanogels based Polyethylene glycol diacrylate (PEGDA) attracted much attention due to their promising application in drug delivery and tissue engineering. Here, PEGDA photopolymerization at 532 nm with different initiating systems was investigated. Nanogels can be obtained using single 2′,4′,5′,7′-tetrabromofluorescein disodium salt (EY) as the photoinitiator. To increase the polymerization rate, EY, triethanolamine (TEOA), and diphenyl iodonium hexafluorophosphate (DPI) were investigated as a three-component initiating system. With that initiating system, the conversion of PEGDA double bond was higher than 90 % in 1 min at extremely low irradiation energy density (P= 0.95 mW/cm 2 ). However, the conversion of PEGDA double bond was only 51.5 % in 1 min at the same irradiation energy density when using EY and TEOA as two-component initiating system. Subsequently, the corresponding mechanism of the three-component (EY-TEOA-DPI) initiating system was illustrated. DPI might participate in two ways of photooxidation and reduction, which dramatically improved the polymerization rate. The EY-TEOA-DPI initiating system is promising to be applied in the preparation of multifunctional hydrogels.
研究领域:
材料科学
·
高分子化学
·
生物医学工程
·
药学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2021
·
IF 5.268
Qing Liu,Jhair Peña,Jinfeng Xing
The strategy of laser beam expansion was used to rapidly prepare nanogels by photopolymerization at 532 nm under low monomer concentration. According to the unique micellar morphology formed by amphiphilic polyethylene glycol diacrylate (PEGDA) in water, the monomer concentration was largely decreased to increase the distance of micellar aggregates. In this case, the photo-crosslinking could prefer to occur inside the micelles instead of crosslinking between the micellar aggregates. The variations of double bond content with reaction time in different beam expansion experiments were investigated. Finally, nanogels with uniform size could be rapidly prepared by regulating the reaction parameters, including monomer concentration, reaction time and power density.
研究领域:
材料科学
·
高分子化学
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
PHOTOCHEMISTRY AND PHOTOBIOLOGY
·
2021
·Vol. 98
·期 1
·132-140
·
IF 3.421
Yuanyuan Peng,Zhipeng Wang,Jhair Peña,Zhiming Guo,Jinfeng Xing
Nanogel is an important kind of biomaterials applied for wound dressings, drug delivery, medical diagnostics and biosensors. The properties of nanogels closely depend on the density of the crosslinking network. In this study, the role of triethanolamine (TEOA) in the effect on the crosslinking degree of nanogels based on poly(ethylene glycol) diacrylate (PEGDA) was investigated and illustrated. The effect of TEOA on the process of photopolymerization at 532 nm and properties of the nanogels was systematically investigated by using UV-vis spectroscopy, FT-IR spectroscopy, 1 H NMR, DLS, SEM, AFM and DSC. In brief, the double-bond conversion of photopolymerization and the crosslinking degree of nanogels can be effectively regulated by TEOA.
研究领域:
材料科学
·
高分子化学
·
生物材料
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2023
·Vol. 106
·期 8
·5078-5085
·
IF 3.9
Bingjun Liu,Bin Han,Na Yan,Min Sun,Guowu Tang,Hao Huang,Qi Qian,Zhongmin Yang
Single-crystal core multimaterial fibers have a wide range of applications in optics. Though some multimaterial fibers with single-element crystal cores have been manufactured successfully, the preparation of binary and multielement crystals is limited by segregation or stoichiometry deviation during the thermal drawing and recrystallization process. This paper presents a new method, several times recrystallization by laser, to solve the crystal segregation problem of binary or multielement crystal core multimaterial fibers.
研究领域:
光学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2026
·
IF 3.1
Peng Zhu,Miaomiao Wang,Dongdong Li,Chang Liu,Zhengbo Qin,Zefeng Hua,Zhong-Fa Sun,Xinyan Yang,Xianfeng Zheng
Plasma amplification laser-induced breakdown spectroscopy (Plasma amplification LIBS) has shown great potential in N elements in water due to high sensitivity, precision, and accuracy. To further reduce interferes of the atmospheric nitrogen, the effect of laser wavelength on the quantitative determination of nitrogen in water was investigated. With short laser wavelength, stronger spectral line intensity, lower interference from atmospheric nitrogen, and superior analytical performance were obtained. The linear coefficient of determination (R²) of the calibration curve improved from 0.2147 to 0.9732, the limit of detection (LOD) was reduced from 18.98 ppm to 3.41 ppm, and the spectral stability, expressed as average relative standard deviation (RSDAV), was reduced from 10.49% to 5.45%. Moreover, the average relative error (REAV) and the root mean square error of cross-validation (RMSECV) for the predicted concentrations were improved by approximately 56.82% and 71.79%, respectively. These results demonstrate that the 532 nm wavelength in plasma amplification LIBS can significantly enhance both the detection sensitivity and the accuracy of quantitative analysis for nitrogen in water.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Yuanyuan Peng,Xinjing Du,Daolian Zhu,Yu Nie,Shengbin Shi,Jinfeng Xing
Drug-loaded nanogels have attracted extensive research interest and shown great potential for many biomedical applications. A facile preparation method for drug-loaded nanogels is desirable to be developed. In this study, a range of nanogels were prepared by combining thiol-ene click reaction and photopolymerization at 532 nm for in situ loading 5-Fluorouracil (NG-S). The drug loading amount was improved by introducing mercaptosuccinic acid (MCA) to trigger thiol-ene click reaction. The drug loading capacity and swelling ratio characteristics of NG-S could be tuned by changing the proportion of PEGDA/MCA and the initial dose of drug. Especially, the drug release performance of the NG-S showed that 5-Fluorouracil presented the relatively excellent behavior of controlled release with a sustained release time up to 20 h in PBS (pH 7.4) at 37 °C. The fitting results of NG-S based on R 2 were consistent with the First order, Weibull and Biexponential kinetic models .
研究领域:
药学
·
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）