APPLIED CATALYSIS B-ENVIRONMENTAL
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2021
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IF 19.503
Xue Ma,Guowei Wang,Lifan Qin,Jue Liu,Bing Li,Yuanan Hu,Hefa Cheng
The transfer rate of photo-generated electrons is a critical factor that determines the photocatalytic efficiency of Z-scheme photocatalytic systems. Here, a novel Z-scheme g-C 3 N 4 -AQ-MoO 3 photocatalyst with anthraquinone (AQ) serving as an e – transfer channel for hydrogen production was proposed. Its enhanced photocatalytic activity is due to the accelerated transfer of e – in the form of charge inside AQ, which also suppresses the recombination of photo-generated e – and h + . In addition, the reduction area is significantly increased by the exfoliation of g-C 3 N 4 into thin layers. Due to the synergistic effect of rapid e – transfer and large reduction area, Z-scheme g-C 3 N 4 -AQ-MoO 3 has a high hydrogen production efficiency that can reach 2018 μmol/g with the presence of triethanolamine as a hole sacrificial agent after 180 min of simulated sunlight illumination. This work provides a new strategy to design and develop Z-scheme photocatalytic systems with excellent electron migration rates and high charge separation efficiency.
研究领域:
材料科学
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能源化学
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产品关联
DOI
高影响因子
Journal of Environmental Sciences
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2025
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IF 6.3
Aiyu Niu,Xin Li,Shanshan Yang,Fei Liu
The chemical reduction of pollutants by Fe 2+ aq -iron oxides heterogeneous systems is an important component of abiotic natural attenuation. A linear free energy relationship (LFERs) can be established between the reduction potential ( E H ) of the heterogeneous system and the kinetic parameter ( k ) of pollutant degradation. However, this relationship was limited to a single iron oxide. The difference in iron oxides particle size and the coexisting anions and cations in groundwater should also be considered. Here, this study investigated the effect of coexisting ions on the nitrobenzene reduction in the Fe 2+ aq -goethite systems with different particle sizes, and explored the response of LFERs. The results indicated that the standard reduction potential ( E 0 H) of Gt-200 was highest among Gt-200, Gt-700 and Gt-1000. However, the nitrobenzene reduction rate exhibited the highest in the Fe 2+ aq -Gt-200 heterogenous systems, which was ascribed to the best adsorption affinity of Fe 2+ aq on Gt-200. Besides, the presence of cations and anions inhibited the reduction rate of nitrobenzene. As for LFERs, the slopes were the same for the Fe 2+ aq -goethite systems with different particle sizes and coexisting ions. The intercept terms were different. The maximum difference in intercept terms was reduced from 0.98 to 0.37 by correcting the LFERs based on the saturated adsorption capacity of Fe 2+ aq . The adsorption performance of Fe 2+ aq on goethite was an important factor affecting the reduction of nitrobenzene. These findings would provide theoretical support for accurately predicting the abiotic natural attenuation rate of nitrobenzene in the presence of coexisting ions in actual groundwater.
研究领域:
环境化学
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地球化学
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水污染与治理
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物理化学
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环境科学
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DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2019
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IF 2.29
Yanfei Fan,Dongdong Li,Dandan Gao,Dewen Zeng,Wu Li
Specific heat capacity of Rb 2 SO 4 (aq) and Cs 2 SO 4 (aq) solutions was determined using a Calvet-type calorimeter from 288.15 K to 338.15 K and from about 0.25 mol·kg −1 to concentration near room temperature solubility limits. For both Rb 2 SO 4 (aq) and Cs 2 SO 4 (aq) solutions, the specific heat capacity decreases with the increase of molality at constant temperature. Combining the heat capacity data determined in this study and other thermodynamic properties ( i.e. water activity, osmotic coefficient, mean ionic activity coefficient, enthalpy of dilution and solubility) reported in literature, thermodynamic and phase equilibria properties of the binary Rb 2 SO 4 + H 2 O and Cs 2 SO 4 + H 2 O systems were modelled using a comprehensive thermodynamic framework, in which a Pitzer-Simonson-Clegg model was applied to represent the non-ideality of aqueous phases. The models can represent all the properties over wide temperature and concentration ranges. This study forms a basis for solubility prediction in multi-component systems containing Rb and Cs sulfates.
研究领域:
物理化学
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热力学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2016
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IF 2.196
Dandan Gao,Dongdong Li,Wu Li
Solubility of RbCl(cr) and CsCl(cr) in pure water were determined at subzero temperatures. The solubility of RbCl(cr) and CsCl(cr) decreased with temperature increment. Specific heat capacity of RbCl(aq) and CsCl(aq) solutions were determined at 298.15 K and concentration to near saturation. The specific heat capacity of RbCl(aq) and CsCl(aq) solutions decreased with concentration increment and for the same molality the specific heat capacity of CsCl(aq) is smaller than that of RbCl(aq). A temperature dependent thermodynamic model based on the Pitzer-Simonson-Clegg activity coefficient equations was used to represent the activity, thermal and solid-liquid equilibria properties of RbCl + H 2 O and CsCl + H 2 O systems. The obtained models can reproduce and predict the thermodynamic properties and phase diagram of the two binary systems well for the temperature range from 200 K to 370 K. The present models have an advantage especially at subzero temperatures due to the utilization of low temperature solubility experimental data in parameterization.
研究领域:
物理化学
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热力学
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN JOURNAL OF PHARMACOLOGY
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2020
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IF 3.263
Bi-Yun Lin,Wen-Lin Liu,Hui Huang,Ya-Guang Hu,Sha Gong,Yu-Hua Meng,Jun Yan,Yuan-Zhi Lu,Hua-Lin Chen
The important physiological function of microtubules makes them an indispensable and clinically effective target of anti-tumor agents. Herein, we sought to design, synthesize, and evaluate a novel 4-anilinoquinazoline derivative and identify its anti-tumor activity in vitro and in vivo. The novel compound, N -(4-methoxyphenyl)- N -methyl-2-(methyl- d 3 )quinazolin-4-amine ( AQ-4 ), was identified as a representative scaffold and potent microtubule-targeting agent. As a promising antimitotic agent , AQ-4 displayed remarkable anti-tumor activity with an average IC 50 value of 19 nM across a panel of 14 human cancer cell lines. AQ-4 also exhibited nearly identical potent activities against drug-resistant cells, with no evidence of toxicity towards normal cells. A further target verification study revealed that AQ-4 targets the tubulin-microtubule system by significantly inhibiting tubulin polymerization and disrupting the intracellular microtubule spindle dynamics. According to the results of mechanism study, AQ-4 induced cell cycle arrest in the G 2 /M phase, promoting evident apoptosis and a collapses of mitochondrial membrane potential . The superior anti-tumor effect of AQ-4 in vivo suggests that it should be further investigated to validate its use for cancer therapy.
研究领域:
肿瘤学
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药理学
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药物化学
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Wei Sun,Mushan Xie,Bo Shi,Zhixuan Zhu,Jian Zhang,Ying Wang,Jing Bian,Haibo Wang,Chun Zhao
The selective and simultaneous removal of antibiotics (ABs), antibiotic-resistant bacteria (ARBs), and antibiotic resistance genes (ARGs) from complex water matrices is crucial but remains challenging. Herein, relatively pure nonradical oxidation systems of singlet oxygen ( 1 O 2 ) and reactive trivalent manganese (Mn( III ) aq ) were established through electrofiltration-activated peroxymonosulfate and permanganate processes, respectively. Both systems simultaneously removed ABs, ARBs, and > 99 % of 20 selected ARGs within 15 min, while the addition of anions and nature organic matter slightly inhibited ARB inactivation. A multiperspective investigation confirmed that 1 O 2 demonstrated superior efficacy in ARB inactivation and protein damage compared to Mn( III ) aq , whereas Mn( III ) aq destroyed the ARB cell membrane, induced oxidative stress, and damaged almost all ARGs more rapidly than 1 O 2 . In particular, 1 O 2 exhibited selectivity toward four ARGs, which was attributed to a positive dependence on the 5′-GG-3′ doublet content. Moreover, 1 O 2 and Mn( III ) aq significantly reduced the risks of ARB regrowth and horizontal gene transfer of ARGs while providing resilience in real water matrices with improved energy-effectiveness. The findings of this study offer new insights into nonradical reactive species dominated advanced oxidation processes for controlling antibiotic resistance in real water.
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2020
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IF 2.369
Liuying Ye,Dongdong Li,Ya-Ping Dong,Baoming Xu,Dewen Zeng
The specific heat capacity of NaBO2(aq) solution was determined using a Calvet-type calorimeter at a temperature from 288.15 to 338.15 K and at a concentration from about 0.25 mol·kg–1 H2O to near room temperature solubility limit. Combining these specific heat capacity data and thermodynamic and solid–liquid equilibrium data reported in the literature, a temperature-dependent thermodynamic model was developed for the NaBO2 + H2O system based on Pitzer–Simonson–Clegg activity coefficient equations. The model represents all of the properties over a wide temperature and concentration ranges. Combining the binary models of NaCl + H2O and Na2SO4 + H2O systems published in the previous studies of our group, multitemperature thermodynamic models of the NaBO2 + NaCl + H2O and NaBO2 + Na2SO4 + H2O systems were constructed. These ternary models reproduce the experimental solubility isotherms reported in the literature in general, but some significant inconsistency is still present. More accurate solubility data for these ternary systems at various temperatures are urgent.
研究领域:
物理化学
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热力学
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溶液化学
✓ 已验证
DOI
高影响因子
FOOD CONTROL
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2022
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IF 6.652
Jie-Qiong Wang,Yan-Qing Fu,Daniel Granato,Peigen Yu,Jun-Feng Yin,Liang Zeng,Yong-Quan Xu
The effects of pH (2.2–8.0) and temperature (25–100 °C) on the instrumental color of a model beverage containing (−)-epigallocatechin-3-gallate (EGCG) were investigated. As the pH and temperature increased, the lightness ( L *) decreased while the redness and yellowness ( a* and b* , respectively) increased. Using spectral scanning, it was possible to verify that color changes might be related to the structural rearrangement of the EGCG aqueous solution in the system under alkaline and heating conditions. There were 6 key substances identified in the EGCG solutions, among which (2R)-2-Hydroxy-3-(2,4,6-trihydroxyphenyl)-1-(3,4,5-trihydroxyphenyl)-1-propanone 2- O -gallate ( m/z 473.0720) and theacitrin C/dehydrotheasinensin AQ ( m/z 911.1340) were identified as key coloring substances. Color changes did not decrease antioxidant activity of the beverage model. These results provide new insights on the mechanism of color change during storage of green tea beverages, and enable the understanding of key contributors to the browning of infusions color in tea beverages for the first time.
研究领域:
食品科学
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化学
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饮料技术
✓ 已验证
产品关联
DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2023
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IF 6.8
Qian Ye,Hanbin Wu,Jin Li,Yinyin Huang,Mingliang Zhang,Qianqian Yi,Bin Yan
Anthraquinone is a redox mediator that can effectively catalyze the degradation of azo dyes by promoting the electron transfer. In this study, a mediator membrane with poly (vinylidene fluoride) (PVDF) as the membrane support and 1,8-dichloroanthraquinone (1,8-AQ) and graphene oxide (GO) as the additives was prepared and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), mercury intrusion porosimetry (MIP), atomic force microscopy (AFM) and water contact angle. The introduction of GO increases the pure water flux of the membrane to 258.56 ±12.93 L/(m 2 ·h). Its catalytic performances for the biodegradation of azo dyes were evaluated. Under the optimized conditions, the 1,8-AQ/GO/PVDF composite membrane is able to improve the dye degradation efficiency 2.2 times for reactive red X-3B and 1.1 times for acid red B, as compared with PVDF membrane. In addition, the mediator membrane maintains stable and high catalytic efficiency in the cyclic test and over 90 % dye degradation efficiency is still obtained after 5 cycles of decolorization. These results suggest the great application potentials of the 1,8-AQ/GO/PVDF membrane in the dye wastewater treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2013
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IF 3.535
Zhenning Xu,Mo Wang,Tingting Zhou,Huanshun Yin,Shiyun Ai
In this article, we presented an electrochemical method for detection of DNA methylation and assay of DNA methyltransferase (MTase) activity using methylene blue (MB) as electrochemical indicator. After the DNA hybrid was methylated by T. aq I MTase, it could not be cleaved by Hinc II endonuclease. On the contrary, the double DNA without methylation could be cleaved, which would decrease the amount of intercalated MB. Thus, the DNA methylation status and MTase activity could be determinated based on the voltammetric signal change of MB. The methylation site could be found based on this method. The electrochemical signal of MB increased linearly with increasing T. aq I MTase concentration from 0.1 to 100 U/mL. Moreover, the inhibition investigation demonstrated that fisetin could inhibit the T. aq I MTase activity with the IC 50 value of 280 μM. Therefore, the screening of the inhibitors of MTase could be accomplished using the novel method.
研究领域:
生物化学
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分子生物学
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分析化学
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2024
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IF 12.2
Ying Ren,Yue Wang,Yang Wang,Xia Ning,Guangke Li,Nan Sang
Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are a class of emerging environmental contaminants that exhibit high toxicity compared to parent PAHs. In addition to carcinogenic, teratogenic and mutagenic effects, recent studies show their potential to cause endocrine disruption, but the reports are controversial. In this study, we employed hormone receptors (ERα/AR/GRα/TRβ)-mediated dual luciferase reporter gene assay and molecular docking, and found that five typical OPAHs exhibited agonistic activity towards hormone receptors, and hydrogen bonding and hydrophobic interactions are the primary binding forces involved in OPAHs-receptor interactions. Then, we developed a weighted scoring system coupled with computerized screening and clarified that 1,2-benzanthraquinone (BAQ) had the strongest hormonal effects, while anthraquinone (AQ) exhibited the weakest effects. Using the in vivo exposure-response model, we clarified that BAQ induced hormone receptor-coupled developmental toxicity in zebrafish larvae, evidenced by increased expression of androgen receptors and key genes involved in hormone synthesis, pericardial edema, and reduced body length. Importantly, we successfully constructed androgen response element-enhanced green fluorescent protein (ARE-EGFP) transient transfection zebrafish embryos, and confirmed the androgenic potency of BAQ, but not AQ. These findings highlight the endocrine-disrupting effects in the risk management of OPAHs.
研究领域:
环境毒理学
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分子生物学
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内分泌学
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发育生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Xiaoqing Zhao,Jing Wang,Hou Chen,Hui Xu,Liangjiu Bai,Wenxiang Wang,Huawei Yang,Donglei Wei,Baiqing Yuan
A novel electrochemical immunoassay platform for multi-signal amplification has been constructed and applied to the simultaneous detection of three tumor markers (TMs). The platform was successfully developed by polyethyleneimine (PEI)-polydopamine (PDA)/reduced graphene oxide (rGO) nanocomposites. PDA/rGO as the substrates can simultaneously load with detection antibodies (Ab 2 ) and large amounts of PEI, which PEI were further used to immobilize different signal labels. Three TMs of carcinoembryonic antigen (CEA), prostate specific antigen (PSA) and alpha fetoprotein (AFP) were employed as potential factors. Ferrocenecarboxylic acid (Fc), anthraquinone-2-carboxylic acid (Aq) and acetylsalicylic acid (ASA) were employed as distinguishable signal labels. Electrochemical responses of designed sandwich-type immunosensor were successfully investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The multiplexed immunoassay displayed excellent linear response in the range of 0.102 pg/mL–112 ng/mL for CEA and PSA, 0.117 pg/mL–117 ng/mL for AFP. The detection limit of three TMs were 91 fg/mL, 101 fg/mL and 83 fg/mL for CEA, PSA and AFP, respectively. Moreover, this electrochemical immunoassay platform exhibited excellent reproducibility, sensitivity and selectivity for the simultaneous detection of multiple biomarkers.
研究领域:
生物医学工程
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分析化学
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纳米技术
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电化学
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生物传感器
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）